Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice

The 5-HT3 receptor for serotonin is expressed within limbic structures and is known to modulate neurotransmitter release, suggesting that this receptor may influence learning and memory. Perturbations in serotonergic neurotransmission lead to changes in the ability to attend, learn, and remember. To examine the role of 5-HT3 receptors in learning, memory, and attention, 5-HT3 receptor overexpressing (5-HT3-OE) transgenic mice and their wild-type littermates (WT) were tested in Pavlovian contextual and cued fear conditioning, fear extinction, and latent inhibition (LI) paradigms. Prepulse inhibition (PPI) was assessed to reveal changes in sensorimotor gating. Additionally, anxious behaviors, shock sensitivity, and reactions to novel stimuli were evaluated. 5-HT3-OE mice displayed enhanced contextual conditioning, whereas cued conditioning remained the same as that of WT mice. 5-HT3-OE mice did not differ from WT in extinction rates to either the context or cue. LI was enhanced for 5-HT3-OE mice compared to WT. PPI remained unchanged. No differences in sensitivity to footshock or startle were found. However, 5-HT3-OE mice demonstrated heightened exploratory behavior in response to novel environmental stimuli and decreased anxiety as measured in the elevated plus-maze. Results indicate that overexpression of the 5-HT3 receptor in mouse forebrain results in enhanced hippocampal-dependent learning and attention. Enhanced inspective behavior in response to novelty may contribute to the observed improvements in learning, memory, and attention due to 5-HT3 receptor overexpression.     

Motivated to Forgive? Partisan Scandals and Party Supporters

In this study, we investigate how partisan motivations shape voters' reactions to a political scandal by drawing on a unique survey experiment fielded immediately after Justin Trudeau's brownface/blackface scandal broke during the 2019 Canadian election. We thus explore motivated reasoning in real time in a competitive and highly partisan election context. Are voters more willing to forgive politicians for past behavior when their own party leader's impropriety is cued? To what extent do personal interests, such as cross-pressures or electoral concerns, affect the motivation to forgive? Our findings show that partisan-motivated reasoning is overwhelmingly powerful, producing politically biased judgments of politicians implicated in scandals. Furthermore, voters' willingness to forgive scandals is also influenced by “strategic” considerations, in that preferences over which political party wins or loses in the election affect opinions about whether someone should be forgiven or whether the scandal is considered important at all. However, we find no evidence that personal involvement in the issue raised by the scandal conditions partisan motivations. We posit that the environment—in this case, a competitive election—is an important consideration for understanding the extent and limits of partisan-motivated reasoning.     

Comparing predictive validity in a community sample: High-dimensionality and traditional domain-and-facet structures of personality variation

Prediction of outcomes is an important way of distinguishing, among personality models, the best from the rest. Prominent previous models have tended to emphasize multiple internally consistent “facet” scales subordinate to a few broad domains. But such an organization of measurement may not be optimal for prediction. Here, we compare the predictive capacity and efficiency of assessments across two types of personality-structure model: conventional structures of facets as found in multiple platforms, and new high-dimensionality structures emphasizing those based on natural-language adjectives, in particular lexicon-based structures of 20, 23, and 28 dimensions. Predictions targeted 12 criterion variables related to health and psychopathology, in a sizeable American community sample. Results tended to favor personality-assessment platforms with (at least) a dozen or two well-selected variables having minimal intercorrelations, without sculpting of these to make them function as indicators of a few broad domains. Unsurprisingly, shorter scales, especially when derived from factor analyses of the personality lexicon, were shown to take a more efficient route to given levels of predictive capacity. Popular 20^th-century personality-assessment models set out influential but suboptimal templates, including one that first identifies domains and then facets, which compromise the efficiency of measurement models, at least from a comparative-prediction standpoint. © 2020 European Association of Personality Psychology     

Positive affect and the experience of meaning in life

Six studies examined the role of positive affect (PA) in the experience of meaning in life (MIL). Study 1 showed strong relations between measures of mood, goal appraisals, and MIL. In multivariate analyses, PA was a stronger predictor of MIL than goal appraisals. In Study 2, the most consistent predictor of the experience of meaning in a day was the PA experienced that day. Later, global MIL was predicted by average daily PA, rather than average daily MIL. Study 3 demonstrated no prospective relations between measures of MIL and PA over 2 years. In Study 4, priming positive mood concepts enhanced MIL. In Study 5, manipulated positive mood enhanced ratings of MIL for those who were not given an attributional cue for their moods. In Study 6, PA was associated with a high level of distinction between meaningful and meaningless activities. Results indicate that positive moods may predispose individuals to feel that life is meaningful. In addition, positive moods may increase sensitivity to the meaning-relevance of a situation.     

Group size and the framing effect:

Past research provides conflicting evidence for the role of value in the appearance of framing effects. In this study, the effects of frame and group size were examined using scenarios about less valuable and more valuable groups (animal vs. human). In addition, two picture manipulations, intended to increase the value of the group, were presented. Choice patterns differed for the human and animal groups, with participants exhibiting greater risk seeking overall for the human scenario and showing a framing effect for humans but not animals when no pictures were presented. A small group size increased the proportion of risky choices for both the animal and human scenarios. Presenting pictures with names did lead to framing effects for animals, but providing pictures or pictures and names eliminated framing effects for the human scenario. These findings suggest that the relationship between value and framing effects is a matter of degree.     

The effects of exposure to muscular male models among men: exploring the moderating role of gym use and exercise motivation

This study examines the effects of exposure to the muscular male body ideal on body-focused negative affect among male gym users and non-exercisers. As hypothesized, the impact of media exposure depended on men's exercise status. Non-exercisers (n = 58) reported greater body-focused negative affect after exposure to images of muscular male models than after neutral images (no model controls), whereas gym users (n = 58) showed a tendency for less body-focused negative affect after the model images than after the control images. Furthermore, the extent to which gym users were motivated to increase strength and muscularity moderated these exposure effects; men who reported stronger strength and muscularity exercise motivation reported a greater degree of self-enhancement after exposure to the muscular ideal. The findings are interpreted with respect to likely differences in motives for social comparisons.     

Interpersonal reactions to suicide attempt: the role of respondent causal attributions

Interpersonal responses to a depressed person with or without a suicide attempt were examined. It was hypothesized that the depressed person who attempted suicide would receive higher negative attributions and interpersonal rejection, and that attributions would mediate the relationship between exposure to a depressed person and rejection. Contrary to hypotheses, respondents were more willing to interact with, held higher esteem for, and endorsed lower negative attributions for the depressed person who attempted suicide. Mediation hypotheses were supported. Findings suggest that a suicide attempt may promote less negative attributions toward depressed individuals, which in turn dampen negative interpersonal reactions.     

The Questionnaire Big Six in 26 Nations: Developing Cross‐Culturally Applicable Big Six,Big Five and Big Two Inventories

The Big Five is a useful model of attributes now commonly used in cross‐cultural research, but without the support of strong measurement invariance (MI) evidence. The Big Six has been proposed as a cross‐culturally informed update, and the broader Big Two (Social Self‐Regulation and Dynamism) draws on even more cross‐cultural evidence. However, neither has been rigorously tested for cross‐cultural MI. Here a Big Six inventory (36QB6) and measures of the Big Five and Big Two derived from it were tested and refined for cross‐cultural usability in samples from 26 nations, divided into three subsets. Confirmatory factor analysis of the models in the first subset of nations demonstrated fit as strong in translation as typical personality measures achieve in their nation of origin (although poor per standard benchmarks). Items that performed inconsistently across cultures were removed, and alternates considered in a second subset of nations. Fit and invariance were improved for refined 30‐item QB6, 25‐item Big Five and 14‐item Big Two measures in the third subset of nations. For all models, decrease in comparative fit index between MI levels was larger than .01, indicating lack of support for higher levels. Configural and factorial invariance were relatively stronger, compared to scalar and full. Copyright © 2014 European Association of Personality Psychology