Awareness and Preferences Regarding <Emphasis Type="Italic">BRCA1/2</Emphasis> Genetic Counseling and Testing Among Latinas and Non-Latina White Women at Increased Risk for Hereditary Breast and Ovarian Cancer

This study was an investigation of awareness, cognitions, and psychosocial and educational needs related to genetic counseling and testing among Latinas and non-Latina whites at increased risk for having a BRCA1/2 mutation. Sixty-three Latina and eighty-four non-Latina white women completed telephone surveys employing a mixture of quantitative and qualitative questions assessing awareness, benefits, risks, barriers, and genetic counseling communication preferences regarding BRCA1/2 testing. Among participants who had not previously had genetic counseling/testing, 56.9% of Latinas (29/51) and 34.8% of non-Latina white participants (24/69) were unaware of the availability of BRCA1/2 testing. In multivariate logistic regression analysis, Latina ethnicity was the only statistically significant independent factor associated with lack of awareness (OR = 0.42; 95% CI = 0.19–0.35). No appreciable differences were noted between ethnic groups regarding perceived benefits of BRCA1/2 testing or desired genetic counseling topics. These findings underscore the importance of increasing awareness of cancer genetic counseling and genetic testing among both Latina and non-Latina white populations.     

Emotion and the Self-Serving Bias

The influence of specific emotions (guilt and revulsion) on the self-serving bias was investigated. Participants were recruited from an undergraduate population. There were 360 participants (132 male) with a mean age of 19.41 years. Participants took part in an online study, which involved taking a ten-question test, completing an emotional induction, receiving test feedback, and making an attribution for test performance. Results revealed a significant effect of feedback (p < 0.001) indicating the self-serving bias. Results also revealed a significant effect of emotion over this self-serving bias. Both guilty and revolted participants made less self-enhancing attributions for success (p = 0.04), and less self-protecting attributions for failure (p = 0.006). The hypothesis that the valence of specific emotions influences the self-serving bias was supported. No support was found for the hypothesis that the appraisal dimensions of specific emotions influence the self-serving bias. Theoretical and practical implications are discussed.     

Dissociative tendencies and right-hemisphere processing load: effects on vigilance performance

The present study was designed to explore the relationship between self-reported dissociative experiences and performance in tasks eliciting right-hemisphere processing load. Thirty-four participants (10 men and 24 women) performed a vigilance task in two conditions: with task-irrelevant negative-arousing pictures and task-irrelevant neutral pictures. Dissociation was assessed with the Dissociative Experience Scale. Consistent with theories positing right-hemisphere deregulation in high non-clinical dissociators, dissociative experiences correlated with greater vigilance decrement only in the negative picture condition. As both the vigilance task and negative picture processing are right lateralized, this result provides support for a right-hemisphere dysfunction in high dissociators, at least in negative conditions.     

The change probability effect: incidental learning, adaptability, and shared visual working memory resources

Statistical properties in the visual environment can be used to improve performance on visual working memory (VWM) tasks. The current study examined the ability to incidentally learn that a change is more likely to occur to a particular feature dimension (shape, color, or location) and use this information to improve change detection performance for that dimension (the change probability effect). Participants completed a change detection task in which one change type was more probable than others. Change probability effects were found for color and shape changes, but not location changes, and intentional strategies did not improve the effect. Furthermore, the change probability effect developed and adapted to new probability information quickly. Finally, in some conditions, an improvement in change detection performance for a probable change led to an impairment in change detection for improbable changes.     

Impaired ability to give a meaning to personally significant events in patients with schizophrenia

Schizophrenia is a severe mental illness affecting sense of identity. Autobiographical memory deficits observed in schizophrenia could contribute to this altered sense of identity. The ability to give a meaning to personally significant events (meaning making) is also critical for identity construction and self-coherence. Twenty-four patients with schizophrenia and 24 control participants were asked to recall five self-defining memories. We assessed meaning making in participants’ narratives (spontaneous meaning making) and afterwards asked them explicitly to give a meaning to their memories (cued meaning making). We found that both spontaneous and cued meaning making were impaired in patients with schizophrenia. This impairment was correlated with executive dysfunctions and level of negative symptoms. Our results suggest that patients’ difficulties in drawing lessons about past experiences could contribute to explain the lack of coherence observed in their life trajectories and their impaired social adjustment abilities. Implications for psychotherapy are also discussed.     

Pain Intensity,Psychological Inflexibility,and Acceptance of Pain as Predictors of Functioning in Adolescents with Juvenile Idiopathic Arthritis: A Preliminary Investigation

Juvenile Idiopathic Arthritis (JIA) is a chronic rheumatic disease associated with pain and maladjustment. This study investigated whether pain, acceptance of pain, and psychological inflexibility uniquely predicted functional disability, anxiety, general quality of life (QOL), and health-related quality of life (HQOL) among adolescents with JIA. Twenty-three adolescents with JIA and pain were recruited from a pediatric rheumatology clinic. Participants completed self-report measures pertaining to the key study variables. A series of multiple regression analyses demonstrated that higher pain uniquely predicted higher functional disability. Greater psychological inflexibility uniquely predicted higher anxiety, lower general QOL, and lower HQOL. Increases in acceptance of pain were found to be uniquely related to increases in general QOL. These data confirm prior findings that pain impacts functioning, and provide preliminary findings that psychological inflexibility and acceptance may be important targets of psychological intervention for youth with JIA and pain to improve functioning and QOL.     

Forgiveness in Younger,Middle-Aged and Older Adults: Age and Gender Matters

The present study investigated age and gender differences in forgiveness of real-life transgressions. Emerging and young, middle-aged, and older adults recalled the most recent and serious interpersonal transgression and then completed the Transgression-Related Interpersonal Motivations Inventory (TRIM-18), which measured their avoidance, revenge, and benevolence motivation toward an offender and indicated to what extent they are generally concerned with the subject of forgiveness. The results revealed a trend among middle-aged adults to express more avoidance than younger adults. Moreover, young men had a greater motivation to seek revenge than middle-aged and older men. No such age differences were apparent for women. Additionally, forgiveness was a more manifest subject in everyday life for middle-aged adults and women. These findings emphasize the importance of age and gender when investigating forgiveness.     

In vitro hippocampal gamma oscillation power as an index of in vivo CA3 gamma oscillation strength and spatial reference memory

Neuronal synchronisation at gamma frequencies (30-100 Hz) has been implicated in cognition and memory. Gamma oscillations can be studied in various in vitro models, but their in vivo validity and their relationship with reference memory remains to be proven. By using the natural variation of wild type C57bl/6J mice, we assessed the relationships between reference memory and gamma oscillations recorded in hippocampal area CA3 in vivo and in vitro. Local field potentials (LFPs) were recorded from area CA3 in behaviourally-characterised freely moving mice, after which hippocampal slices were prepared for recordings in vitro of spontaneous gamma oscillations and kainate-induced gamma oscillations in CA3. The gamma-band power of spontaneous oscillations in vitro correlated with that of CA3 LFP oscillations during inactive behavioural states. The gamma-band power of kainate-induced oscillations correlated with the activity-dependent increase in CA3 LFP gamma-band power in vivo. Kainate-induced gamma-band power correlated with Barnes circular platform performance and object location recognition, but not with object novelty recognition. Kainate-induced gamma-band power was larger in mice that recognised the aversive context, but did not correlate with passive avoidance delay. The correlations between behavioural and electrophysiological measures obtained from the same animals show that the gamma-generating capacity of the CA3 network in vitro is a useful index of in vivo gamma strength and supports an important role of CA3 gamma oscillations in spatial reference memory.     

Factorial validity and measurement invariance of the Revised Physical Self-Perception Profile (PSPP-R) in three countries

The revised physical self-perception profile (PSPP-R) was constructed to measure both perceived competence and importance linked to domains of the physical self. In the present study, we tested the factorial validity of the PSPP-R, using confirmatory factor analytic approach, on samples of university students from three different countries: Sweden, Turkey, and the UK. Multi-sample covariance structure analyses were also used to test the invariance of the PSPP-R across the three national samples. First-order four-factor models, including the latent factors of sport competence, physical conditioning, body attractiveness and physical strength, demonstrated good-fit with the data both for competence and importance factors. Second-order factor models, incorporating the second-order latent domain factor of physical self-worth also exhibited good-fit with the data. Factor patterns and covariances were invariant across samples for both competence and importance scales. Item intercepts were also invariant for the importance scales, whereas partial invariance of intercepts was supported for competence scales. The results are discussed with reference to the validity of the original physical self-perception profile and cross-cultural studies on the physical self.     

Piecing together numerical language: children's use of default units in early counting and quantification

When asked to ‘find three forks’, adult speakers of English use the noun ‘fork’ to identify units for counting. However, when number words (e.g. three) and quantifiers (e.g. more, every) are used with unfamiliar words (‘Give me three blickets’) noun‐specific conceptual criteria are unavailable for picking out units. This poses a problem for young children learning language, who begin to use quantifiers and number words by age 2, despite knowing a relatively small number of nouns. Without knowing how individual nouns pick out units of quantification – e.g. what counts as a blicket– how could children decide whether there are three blickets or four? Three experiments suggest that children might solve this problem by assigning ‘default units’ of quantification to number words, quantifiers, and number morphology. When shown objects that are broken into arbitrary pieces, 4‐year‐olds in Experiment 1 treated pieces as units when counting, interpreting quantifiers, and when using singular–plural morphology. Experiment 2 found that although children treat object‐hood as sufficient for quantification, it is not necessary. Also sufficient for individuation are the criteria provided by known nouns. When two nameable things were glued together (e.g. two cups), children counted the glued things as two. However, when two arbitrary pieces of an object were put together (e.g. two parts of a ball), children counted them as one, even if they had previously counted the pieces as two. Experiment 3 found that when the pieces of broken things were nameable (e.g. wheels of a bicycle), 4‐year‐olds did not include them in counts of whole objects (e.g. bicycles). We discuss the role of default units in early language acquisition, their origin in acquisition, and how children eventually acquire an adult semantics identifying units of quantification.