Neurodevelopmental model of long-term outcomes of adult survivors of childhood brain tumors

Childhood brain tumors and related treatments disrupt the developing brain and have a cascading impact on core cognitive skills and intellectual (intelligence quotient [IQ]) and academic achievement outcomes. Theoretical models for this cascade have been developed based on the literature, but no studies thus far have empirically evaluated the models. The current study aimed to empirically test the two extant models and generate a new data-driven model of the relationships among neurodevelopmental risk factors, core cognitive skills (i.e., processing speed, attention span, working memory), and IQ and achievement outcomes. Fifty-seven adult survivors of childhood brain tumors and fifty-seven demographically matched neurotypical individuals were included in the current study. The average age at brain tumor diagnosis was 8 years, and the average time since diagnosis was 17 years. Three a priori path models tested the hypothesized relationships among variables. Results of the path analyses revealed that the hybrid model best fit the data for both survivors and controls based on all statistical criteria. For survivors, processing speed was the core cognitive skill most widely associated with neurodevelopmental risk factors and outcomes. However, working memory and attention span also had unique contributions to IQ and academic achievement. Processing speed appears to be the central cognitive skill that disrupts the other core cognitive skills of attention span and working memory, and all three make a unique contribution to IQ and academic achievement. This is best demonstrated by a novel neurodevelopmental model that combines components of two earlier untested theoretical models.     

Linking Femininity, Weight Concern, and Mental Health among Latina, Black, and White Women

Studies examining women's appearance ideals and weight concern have predominantly relied on samples of White women. This study addresses this oversight, examining the different relations among embodied femininity, weight concern, and depressive symptomatology that exist for different groups of women. Using a nationally representative sample of women between the ages of 18 and 45, bivariate analyses were conducted using three samples of Latina, Black, and White women. When sample size allowed, a multivariate model was tested (i.e., for Black and White respondents). Results confirm, as hypothesized, different patterns of relations between embodied femininity, weight concern, and depressive symptomatology for each of the samples. At the bivariate level, embodied femininity, weight concern, and depressive symptomatology were positively intercorrelated among Latina respondents. Whereas weight concern fully mediated the relation between embodied femininity and depressive symptomatology for the White respondents, the mediational model was not borne out for the Black respondents. For the latter, although embodied femininity and weight concern were related, weight concern was unrelated to depressive symptoms. Both of these patterns are discussed, as well as the need for greater empirical sensitivity to various constructions of femininity among women of different ethnicities.     

The Moderating Effect of Depression Symptoms on the Concordance between the Experience and Verbal Disclosure of Emotion

Within-person studies of emotional disclosure have found evidence of a disclosure-discordance effect of depression, whereby the positive association between the intensity of one’s emotional experience and verbal disclosure of that experience weakens with increasing depression symptoms. Because these previous studies have exclusively been naturalistic ones, we examined the disclosure-discordance effect of depression in the lab. Participants (N?=?115) completed a measure of depression symptoms and viewed a series of emotionally evocative photographs. Emotion-expressive behavior while viewing each photograph was rated by judges, subjective emotional experience was assessed via self-report, and emotional disclosure just after the photograph was viewed was rated by different judges. Multilevel analyses indicated that depression symptoms moderated the association between the behavioral (i.e., facial) expression of emotion intensity and disclosure of emotion. Moderation was not supported in analyses with self-reported emotional intensity as a predictor. These findings partly supported the disclosure-discordance effect, and they inform methods of empirically examining the effect of depression symptoms on the verbal disclosure of emotion.

     

Testing the GRIP: An Empirical Examination of the Gender Roles Inhibiting Prosociality Model

Although men and women help others, there are systematic gender differences in the type of helping they perform. Consistent with traditional gender roles and stereotypes, men typically help in agentic ways, and women typically help in communal ways. Drawing on the Theory of Planned Behavior, the Gender Roles Inhibiting Prosociality model predicts that gender stereotypes about gender-inconsistent helping create negative attitudes, restrictive subjective norms, and low self-efficacy that undermine helping intentions, which, in turn, reduce engagement in gender-inconsistent helping contexts. Across three studies (N?=?1,355), we find empirical support for the hypothesized model: When asked to imagine engaging in a gender-inconsistent (vs. gender-consistent) helping scenario, participants anticipated feeling worse, expected others to judge them more negatively, and reported decreased self-efficacy beliefs, and these factors predicted lower intentions to engage in gender-inconsistent helping. Critically, behavioral intentions explained some of the variance in gender-inconsistent helping during the following month. Internal meta-analyses of the differences between gender-consistent and -inconsistent helping on attitudes, subjective norms, self-efficacy, and behavioral intentions across studies revealed small-to-medium average effect sizes (ds?=?0.16—0.47). These results have the potential to inform interventions aimed at increasing helping in all its forms.

     

Posttraumatic Cognitions and Depressive Symptoms in War and Disaster Affected Widows in Sri Lanka: The Role of Community Support

In this study the authors evaluated the associations between war- and disaster-related problems and indicators of psychological distress (posttraumatic cognitions and culturally-specific symptoms of depression) among a sample of Tamil widows in the Eastern Provence of Sri Lanka. Furthermore, community support was evaluated as a mediator of these associations. Surveys were administered to women (N?=?156) in an interview format by trained research assistants who were native Tamil speakers. Mediation hypotheses were evaluated using path analysis. Results showed that war-related problems, but not disaster-related losses, was significantly associated with community support and posttraumatic cognitions, such that higher number of war-problems was associated with lower community support and more posttraumatic cognitions. Community support had a significant negative association with posttraumatic cognitions and depression. Additionally, we found evidence that war-related problems was indirectly associated with depression through community support. Although the magnitude of associations was small, results suggest that contextual problems resulting from years of armed conflict may be associated with less support from one’s community which, in turn, is associated with increased psychological distress. Limitations and implications for intervention and future research are discussed.     

Testing for negligible interaction: A coherent and robust approach

Researchers often want to demonstrate a lack of interaction between two categorical predictors on an outcome. To justify a lack of interaction, researchers typically accept the null hypothesis of no interaction from a conventional analysis of variance (ANOVA). This method is inappropriate as failure to reject the null hypothesis does not provide statistical evidence to support a lack of interaction. This study proposes a bootstrap‐based intersection–union test for negligible interaction that provides coherent decisions between the omnibus test and post hoc interaction contrast tests and is robust to violations of the normality and variance homogeneity assumptions. Further, a multiple comparison strategy for testing interaction contrasts following a non‐significant omnibus test is proposed. Our simulation study compared the Type I error control, omnibus power and per‐contrast power of the proposed approach to the non‐centrality‐based negligible interaction test of Cheng and Shao (2007, Statistica Sinica, 17, 1441). For 2 × 2 designs, the empirical Type I error rates of the Cheng and Shao test were very close to the nominal α level when the normality and variance homogeneity assumptions were satisfied; however, only our proposed bootstrapping approach was satisfactory under non‐normality and/or variance heterogeneity. In general a × b designs, although the omnibus Cheng and Shao test, as expected, is the most powerful, it is not robust to assumption violation and results in incoherent omnibus and interaction contrast decisions that are not possible with the intersection–union approach.     

Quadratic Associations Between Empathy and Depression as Moderated by Emotion Dysregulation

Empathic tendencies have been associated with interpersonal and psychological benefits, but empathy at extreme levels or in combination with certain personal characteristics may contribute to risk for depression. This study tested the moderating role of cognitive emotion regulation in depression's association with empathy using nonlinear models. Young adults (N = 304; 77% female; M = 19 years) completed measures of cognitive emotion regulation strategies, depression, and affective and cognitive empathy. Individuals with good regulation had low levels of depression overall and their depression symptoms were lowest when levels of affective empathy were average. Individuals with poor regulation had high levels of depression overall, particularly when levels of empathy were moderate to high. Extremely high and low levels of cognitive empathy were associated with elevated depression, and this association was not moderated by regulation. These findings suggest tendencies to respond empathically to others’ needs is neither an adaptive nor maladaptive characteristic but rather moderate empathy, particularly in the context of good regulation, may offer the greatest protection against depression.     

An evaluation of resurgence following functional communication training conducted in alternative antecedent contexts via telehealth

Treatments based on differential reinforcement may inadvertently increase the recurrence of problem behavior in the face of challenges because reinforcers for appropriate behavior occur in the same context as problem behavior. The current study evaluated one potential approach to mitigating these problems with differential reinforcement treatments based on behavioral momentum theory. Specifically, appropriate behavior was trained in contexts without a history of reinforcement prior to intervening with problem behavior. Participants were 4 children with autism spectrum disorder. Treatment used telehealth to implement functional communication training (FCT) in three alternative contexts with minimal or no history of reinforcement for problem behavior before initiating FCT in the treatment context. Evaluations of the effects of treatment and tests of resurgence were conducted intermittently during treatment to evaluate maintenance. When FCT treatment was initiated in alternative contexts, initial results were comparable to more typical implementations of FCT. Resurgence was reduced to similar levels during tests of resurgence for all participants when compared to more typical previously published implementations of FCT, but clinically significant reductions in resurgence occurred more quickly in the present study. These findings support training appropriate behavior in an alternative context to mitigate the resurgence of problem behavior during differential reinforcement treatments.