Right frontal EEG asymmetry and behavioral inhibition in infants of depressed mothers

Recent studies have shown associations between maternal psychopathology and inhibited behaviors in infants. Moreover, physiological factors have been identified as affecting the continuity of behavioral inhibition across childhood. The purpose of the present study was to examine electroencephalogram (EEG) activity and inhibited behavior in 12-month-old infants of depressed versus non-depressed and mothers. Repeated measures MANOVAs indicated that the infants of mothers with stable psychopathology had greater relative right frontal EEG asymmetry, a pattern that typically accompanies greater negative affect and greater withdrawal behaviors. Infants of affectively ill mothers also showed more proximal behaviors toward a stranger and a novel toy than infants of well mothers, but fewer non-proximal behaviors toward their mothers. These results are discussed within a framework of behavioral inhibition for infants exposed to early psychopathologies in their mothers.     

Role of the Disease in the Psychological Impact of Pre-Symptomatic Testing for SCA2 and FAP ATTRV30M: Experience with the Disease, Kinship and Gender of the Transmitting Parent

To identify possible factors affecting the psychological impact of pre-symptomatic testing for spinocerebellar ataxia type 2 (SCA2) and familial amyloid polyneuropathy (FAP ATTRV30M), we studied (1) the effect of previous experience with the disease in the family, (2) kinship with the closest affected relative and (3) gender of affected parent, when adapting to test results; as well as (4) differences in the course of psychological wellbeing in 63 subjects ( 28 at-risk for FAP ATTRV30M, and 35 at risk for SCA2), who pursued predictive testing for these diseases, in Cuba and in Portugal. Our research shows that individuals with little or no experience with the disease in their family exhibited more anxiety; at-risk subjects for SCA2 or FAP ATTRV30M who had a first degree relative with the disease showed lower levels of anxiety and depression during pre-symptomatic testing. Also those with an affected mother had lower levels of depression, either immediately, or one year after receipt of test results. Adaptation to pre-symptomatic testing results differed for subjects at-risk for the two different conditions. Unlike the FAP ATTRV30M families, carriers for SCA2 reported pathological levels of depression immediately after-testing (3 weeks), although those levels had returned to normal levels at 6 months. Subjects at-risk for FAP ATTRV30M tended to have less anxiety than those tested for SCA2, at the one-year follow-up. Overall, depression levels improved over time, while anxiety remained more constant. A longer awareness of the disease in the family, closer kinship, and a transmitting mother all lessened the impact of pre-symptomatic testing, as expressed by the post-test levels of anxiety and depression.     

The formation of structurally relevant units in artificial grammar learning

A total of 78 adult participants were asked to read a sample of strings generated by a finite state grammar and, immediately after reading each string, to mark the natural segmentation positions with a slash bar. They repeated the same task after a phase of familiarization with the material, which consisted, depending on the group involved, of learning items by rote, performing a shortterm matching task, or searching for the rules of the grammar. Participants formed the same number of cognitive units before and after the training phase, thus indicating that they did not tend to form increasingly large units. However, the number of different units reliably decreased, whatever the task that participants had performed during familiarization. This result indicates that segmentation was increasingly consistent with the structure of the grammar. A theoretical account of this phenomenon, based on ubiquitous principles of associative memory and learning, is proposed. This account is supported by the ability of a computer model implementing those principles, PARSER, to reproduce the observed pattern of results. The implications of this study for developmental theories aimed at accounting for how children become able to parse sensory input into physically and linguistically relevant units are discussed.     

PROMOTING RECIPROCAL INTERACTIONS VIA PEER INCIDENTAL TEACHING

This study evaluated peer incidental teaching as a strategy for increasing reciprocal peer interactions by children with autism. Three typical preschoolers were trained as peer tutors for 3 young children with autism. During a classroom free-play session, peer tutors used incidental teaching to obtain verbal labels of preferred toys by children with autism. A multiple baseline across the 3 target children showed replicated positive effects of the intervention. Adult supervision and assistance were then faded systematically, with resulting maintenance of increased reciprocal interactions. Multiple measures of the extent and limits of generalization suggested that 1 child increased interactions in free-play periods throughout the day, but none of the children showed increases at lunch. Teacher and peer ratings supported the social validity of positive findings.     

Implicit learning shapes new conscious percepts and representations

We present here the lineaments of a new account of implicit learning, an account that does not rely on the notion of “implicit knowledge.” In this account, improved performance depends on the action of unconscious mechanisms that structure the phenomenal, conscious experience of the world. This integrative view makes groundless the search for dissociations between conscious and unconscious influences that has been at the core of the research on implicit learning and memory. We contrast this view, on the one hand, to Dienes and Berry’s (1997) proposal, which defines implicit learning by analogy with subliminal perception, and, on the other, to Neal and Hesketh’s (1997) episodic account, in which subjective experience is a starting point for inquiry, rather than the phenomenon requiring explanation.     

Effects of external cathodal polarization on classical motor conditioning in dogs

The present study was designed to determine the effects of cathodal polarization on the establishment of motor conditional reflexes (CR's), with faradic shock as reinforcement. Ten dogs were used as controls and another seven as experimental subjects (ES's). In the ES's, stainless-steel electrodes were implanted on the face, infraorbitally, for chronic polarization. Four days later the ES's were trained in a soundproof room with classical conditioning procedures while they were co9nstantly polarized with direct current (1 to 2 ma). Control dogs showed strong (+3 and +4) motor CR's within the first 50reinforced trials, with differentiation after 50 trials. In contrast, the ES's showed poor motor conditioning: six ES's showed poor motor CR's in the first 50 reinforced trials. Only one ES showed prompt, good motor CR's. The fact that cathodal polarization interferes with theestablishment of motor CR's suggests an inhibitory effect on the acquisition of musculoskeletal CR's. It is possible that the inhibitory effects observed are related to the depression produced by cathodal polarization in humans.     

Identifying Community-Based Reinforcers of Adults with Autism and Related Disabilities

A forced-choice preference assessment using pictures and no access upon selection was used to determine preferences for community-based activities with 4 young adults with autism and intellectual disability. High- and low-preference activities were then provided as delayed consequences, using a token economy, for completion of vocational tasks in a concurrent operants paradigm. All participants responded to the contingency associated with earning the high-preference activity and away from the contingency associated with earning the low-preference activity. The results suggest that a pictorial assessment without access is a valid method for identifying community-based activities that will function as reinforcers. This efficient protocol could improve treatment efficacy in applied settings.