Within-person variability in response speed as an indicator of cognitive impairment in older adults

Within-person variability may be an important indicator of central nervous system compromise. In this study, within-person variability in response speed was examined in community-dwelling older adults, ages 64-92 years, using a new framework that takes into account both the extent (single versus multiple domains affected) and nature (amnestic versus non-amnestic) of the cognitive impairment. Those with multiple domains of impairment were more variable than those who showed an isolated area of impairment, regardless of whether memory was one of the domains affected. Further, for those with difficulties in two or more non-memory domains, increased variability was most evident in more cognitively demanding situations, when individuals had to manipulate information held briefly in mind, switch cognitive set or inhibit an automatic response. Finally, group differentiation was better achieved when within-person variability as opposed to mean speed of performance was considered.     

Task feedback effects on conflict monitoring and executive control: relationship to subclinical measures of depression

Emerging evidence suggests that depression is associated with executive dysfunction, particularly after committing errors or receiving negative performance feedback. To test this hypothesis, 57 participants performed two executive tasks known to elicit errors (the Simon and Stroop Tasks) during positive or negative performance feedback. Participants with elevated depressive symptoms (Beck Depression Inventory scores >or= 13) were characterized by impaired posterror and postconflict performance adjustments, especially during emotionally negative task-related feedback. Additionally, for both tasks, depressive symptoms were inversely related to postconflict reaction time adjustments following negative, but not positive, feedback. These findings suggest that subclinical depression is associated with impairments in behavioral adjustments after internal (perceived failure) and external feedback about deficient task performance.     

Influence of vocal cues on learning about objects in joint attention contexts

An experimenter taught infants about a novel toy in two joint attention conditions, one with and one without vocal cues. In test trials, infants viewed the familiar toy and a novel toy. Infants in the Joint Attention plus Voice condition looked significantly longer to the novel toy.     

An open trial of cognitive therapy for chronic insomnia

We describe the development of a cognitive therapy intervention for chronic insomnia. The therapy is based on a cognitive model which suggests that the processes that maintain insomnia include: (1) worry and rumination, (2) attentional bias and monitoring for sleep-related threat, (3) unhelpful beliefs about sleep, (4) misperception of sleep and daytime deficits and (5) the use of safety behaviors that maintain unhelpful beliefs. The aim of cognitive therapy for insomnia is to reverse all five maintaining processes during both the night and the day. In an open trial 19 patients meeting diagnostic criteria for primary insomnia were treated with cognitive therapy for insomnia. Assessments were completed pretreatment, posttreatment and at 3-, 6- and 12-month followup. The significant improvement in both nighttime and daytime impairment evident at the posttreatment assessment was retained up to the 12 month followup.     

Pace alteration and estimation of time intervals

This experiment examined the effects on participants' estimates of interval duration of altering the pace of auditory stimuli contained within "filled" intervals. Because most previous studies on the filled interval effect have utilized visual displays, auditory stimuli were used to assess whether the effect would be present. In addition, previous studies compared two intervals, one of which was filled and the other unfilled. In the present study, both intervals were filled with tones at one of three rates (or "paces"): slow, medium, or fast. 25 participants (20 women) ages 18 to 29 years (M = 20.4, SD = 2.3) were recruited from psychology courses and programs. Participants first heard a "training" interval filled with tones at one of the three paces and then attempted to reproduce the duration of that training interval in the "test" interval. The pace of stimuli in each pair of training and test intervals was varied so participants received all possible combinations of paces of auditory stimuli during the training and test trial sets. Analysis showed that, when training pace was fast and test pace was medium or slow, participants' estimates were longer than the actual test interval durations. Conversely, when training pace was slow and test pace was medium or fast, participants' estimates were shorter than actual test interval durations. In addition, when judging shorter intervals, participants estimated more time had passed than actually had, while they estimated that less time had passed than actually had for longer intervals, thus providing support for Vierordt's law.     

Comparison of scores for abused and nonabused young adults on the Psychological Trauma and Resources Scale

The Psychological Trauma and Psychological Resources Scale has been developed to identify adolescents and adults who have experienced traumatic events, i.e., physical, sexual, or emotional abuse and neglect. The scale also attempts to identify the presence of compensatory or resource factors such as social support that may serve to ameliorate the effects of traumatic events. 98 college participants who reported a history of abuse were compared with 464 nonabused students on the seven subscales. As predicted, the abused participants reported significantly more incidents of abuse and neglect than the nontraumatized group. In addition, the abused group reported receiving less emotional support, and they were less likely to use positive self-talk as a way to decrease emotional distress. These results provide empirical support for using the Psychological Trauma and Psychological Resources Scale to identify individuals with a history of abuse. Findings underscore the importance of assessing resource variables that may moderate the effects of abuse.     

Paradoxes in Double Extension Set Theories

Three systems of double extension set theory have been proposed by Andrzej Kisielewicz in two papers. In this paper, it is shown that the two stronger systems are inconsistent, and that the third, weakest system does not admit extensionality for general sets or the use of general sets as parameters in its comprehension scheme. The parameter-free version of the comprehension principle of double extension set theory is also shown to be inconsistent with extensionality. The definitions of the systems and a self-contained exposition of their properties is given, sufficient to develop the inconsistency proofs.     

Sublexical and Lexical Influences on Gender Assignment in French

Two experiments showed that French native speakers rely on sublexical and lexical cues to allocate gender during word recognition. Sublexical cues were based on whether the word ending was typical for a particular gender rather than neutral with regard to gender. Lexical cues were based on whether the associated definite article was informative (for words beginning with a consonant) or uninformative (for words beginning with a vowel). Classification of single nouns and verification of grammatical combinations of indefinite article and noun led to longer times when both sublexical and lexical cues were uninformative compared with when one or both cues were informative. Verification of ungrammatical combinations of indefinite article and noun yielded separate effects of both cues, though only when monitoring for both semantic and syntactic unacceptability in meaningful phrases did people attend to both cues independently. It was argued that people became more cautious in their gender assignments as task requirements became deeper. If strategic changes as a function of task demands are incorporated, the results are compatible with connectionist models proposing that gender decisions are computed from strength of past associations of the word and gender-specifying elements.     

Reflecting on imagery: a clinical perspective and overview of the special issue of memory on mental imagery and memory in psychopathology

The authors provide an overview of the papers in the special issue of Memory on mental imagery and memory in psychopathology. The papers address emotional, intrusive mental imagery across a range of psychological disorders including post-traumatic stress disorder (PTSD), agoraphobia, body dysmorphic disorder, mood disorders, and psychosis. They include work on information processing issues including modelling cravings, conditioning, and aversions, as well as imagery qualities such as vividness and emotionality. The overview aims to place the articles in a broader context and draw out some exciting implications of this novel work. It provides a clinical context to the recent growth in this area from a cognitive behavioural therapy (CBT) perspective. We begin with PTSD, and consider links to imagery in other disorders. The clinical implications stemming from this empirical work and from autobiographical memory theory are discussed. These include consideration of a variety of techniques for eliminating troublesome imagery, and creating healthy, realistic alternatives.     

Effects of early seizures on later behavior and epileptogenicity

Both clinical and laboratory studies demonstrate that seizures early in life can result in permanent behavioral abnormalities and enhance epileptogenicity. Understanding the critical periods of vulnerability of the developing nervous system to seizure-induced changes may provide insights into parallel or divergent processes in the development of autism. In experimental rodent models, the consequences of seizures are dependent on age, etiology, seizure duration, and frequency. Recurring seizures in immature rats result in long-term adverse effects on learning and memory. These behavioral changes are paralleled by changes in brain connectivity, changes in excitatory neurotransmitter receptor distribution, and decreased neurogenesis. These changes occur in the absence of cell loss. Although impaired cognitive function and brain changes have been well-documented following early-onset seizures, the mechanisms of seizure-induced dysfunction remain unclear.