Exploration and avoidance in rats with lesions in amygdala and piriform cortex

Lesions localized to specific areas of the amygdala and overlying cortex in rats produced differential effects in several behavioral tasks. Three different types of lesions were tested: central, basolateral, and cortex lateral to the amygdala. Lesions restricted to the central nucleus produced increased activity on all parameters studied in an open-field test, but the other two groups were not changed. In one-way active avoidance all three groups with lesions showed deficits. The most pronounced change was observed in the central group. All groups showed the same degree of retention loss, but in forced extinction of one-way active avoidance after retraining, the cortical and basolateral groups were most defective. A fear-reduction hypothesis is proposed for the central lesion. The basolateral and cortical areas may be more specifically involved in passive avoidance behavior.     

Reinforcing effects of prerecorded words and delayed speech feedback on the verbal behavior of a neologistic schizophrenic

The possibility of using prerecorded words and 2-sec. delayed speech feedback as reinforcement in the reconditioning of intelligible verbal responses in a chronic, neologistic schizophrenic patient was investigated. A test situation was devised which involved daily presentation of 100 stimulus word-picture cards to elicit verbal responses. The results indicated that both singly presented prerecorded words and delayed speech feedback apparently strengthened correct and intelligible verbal responding.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Why child neuropsychiatry?]

The author gives a brief survey of the development of Child-Neuropsychiatry in the G.D.R. and subsequently gives reasons for the decision in favor of the unity of neurology and psychiatry as applied to children and juveniles, which is in contrast to developments in other countries. In addition to hygienic, economic, organizational, and medical considerations, this decision was also determined by the fact that a Child-Neuropsychiatrist must, in his practical work as a subspecialist, be able to head a multiprofessional team and, thus, help assure optimum development of a child's personality.     

A method for simulating non-normal distributions

A method of introducing a controlled degree of skew and kurtosis for Monte Carlo studies was derived. The form of such a transformation on normal deviates [X N(0, 1)] isY =a +bX +cX ² +dX ³. Analytic and empirical validation of the method is demonstrated.This work was done while the author was at the University of Illinois at Champaign-Urbana.     

Progressive changes in articulatory patterns in verbal apraxia: A longitudinal case study

This research reports findings in a 10-year study of an apraxic adult, who was one of five subjects described by Shankweiler and Harris, (Cortex, ,2 277–292, 1966). Confusion matrices and feature analysis were used to compare 1965 and 1975 performances. Results indicate that over the 10-year period, errors of place, manner, and omission were markedly reduced. Voicing errors, however, while reduced in total number, still constituted a significant percentage of the patient's residual errors. Implications of these findings are discussed.     

The relative effectiveness of alternative job sources

Vocational research has focused on the occupational choice process and the individual's adjustment to work. Very little research has examined the job search process in which the individual must engage in order to implement occupational choices. This study examines one dimension of the job search process: the relationship between job source and subsequent work experiences. The data reveal that when the respondents initially entered the labor market, those relying on formal job sources tended to work in higher-level occupations and in jobs more closely related to their training than their counterparts who used other job sources. In the longer run, the labor market advantages associated with the use of formal job sources dissipated for the engineering majors but tended to persist for the business alumni.     

Developmental auditory agnosia in the severely retarded: A further investigation

The hypotheses were investigated that (a) ability to recognize the auditory perceptual stimuli for familiar events is a developmental correlate to language acquisition and (b) the low functioning mentally handicapped suffer from auditory agnosia and are impaired in this ability. The subjects were 42 nonretarded children of ages 3 through 6 and 53 severely and moderately retarded, noninstitutionalized students. The retarded subjects were matched by mental age to the chronological age of the nonretarded children. The stimuli were 49 environmental sounds; the task consisted of sound-and-picture matching-to-sample. Group membership and developmental age were the factors in an analysis of variance design. The results revealed a strong effect of developmental age (p <. 0001). The effect of group was not significant, indicating that auditory agnosia may not be common among the lower functioning retarded. The assumption that agnosia may be a major factor underlying the language disability of the severely retarded was reexamined. It was suggested that the severely retarded achieve the requisite perceptual-semantic knowledge base for language too late, after the critical age for spontaneous and efficient language learning has passed.