Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice

The 5-HT3 receptor for serotonin is expressed within limbic structures and is known to modulate neurotransmitter release, suggesting that this receptor may influence learning and memory. Perturbations in serotonergic neurotransmission lead to changes in the ability to attend, learn, and remember. To examine the role of 5-HT3 receptors in learning, memory, and attention, 5-HT3 receptor overexpressing (5-HT3-OE) transgenic mice and their wild-type littermates (WT) were tested in Pavlovian contextual and cued fear conditioning, fear extinction, and latent inhibition (LI) paradigms. Prepulse inhibition (PPI) was assessed to reveal changes in sensorimotor gating. Additionally, anxious behaviors, shock sensitivity, and reactions to novel stimuli were evaluated. 5-HT3-OE mice displayed enhanced contextual conditioning, whereas cued conditioning remained the same as that of WT mice. 5-HT3-OE mice did not differ from WT in extinction rates to either the context or cue. LI was enhanced for 5-HT3-OE mice compared to WT. PPI remained unchanged. No differences in sensitivity to footshock or startle were found. However, 5-HT3-OE mice demonstrated heightened exploratory behavior in response to novel environmental stimuli and decreased anxiety as measured in the elevated plus-maze. Results indicate that overexpression of the 5-HT3 receptor in mouse forebrain results in enhanced hippocampal-dependent learning and attention. Enhanced inspective behavior in response to novelty may contribute to the observed improvements in learning, memory, and attention due to 5-HT3 receptor overexpression.     

Psychic reality and the analytic relationship

In this article I have argued that the more linear transformations or desymbolized expressions of one's earliest relationships are always a part of psychic reality and represent a unique opportunity in the analytic situation to transform a person's emotional orientation to the world. A necessary condition for this to come about is the analyst's capacity for sustained interest in the patient. This interest, which goes well beyond an intellectual one, can be threatened by countertransference as well as certain assumptions the analyst has about the nature of the analytic process. The analyst's belief in the analytic process, a belief that can only come from his or her own analysis, is seen as crucial in helping the transformational process that occurs in a successful analysis.     

Adjustment to parental divorce: An examination of the differences between counselled and non-counselled children

To evaluate an innovative counselling service, two groups of children of divorce were studied: one that was receiving counselling and a non-counselled group. The differences between the two groups were examined in relation to such areas as self-esteem and their relationships with their parents prior and subsequent to separation.     

Fairness Evaluations of Encounters With Police Officers and Correctional Officers1

The fairness of treatment can be inferred from 2 aspects of the relationship between authority and other party: the person-related aspect and the role-related aspect. One hundred seventy-five American detainees were interviewed about their encounters with police officers and correctional officers. The role-related aspect affected procedural fairness judgments most when first-time incarcerated detainees evaluated the encounter with police officers. The person-related aspect affected procedural fairness judgments most when first-time detainees and repeatedly incarcerated detainees evaluated encounters with correctional officers. Consequences for the group value model of procedural fairness as well as for the legal practice are discussed.     

Volitional action and inaction in the lives of undergraduate students: State orientation, procrastination and proneness to boredom

The purpose of this research was to examine the relation between state orientation, proneness to boredom and procrastination as proposed in Kuhl's theory of action (Kuhl, 1994a). The findings from two studies are reported. Based on data collected from 143 undergraduate students on the Action Control Scale (Kuhl, 1994b), study 1 revealed arousal, avoidance and decisional procrastination to be positively related to state orientation. Results of study 2 (n = 120) demonstrated proneness to boredom to be positively related to state orientation, arousal procrastination and decisional procrastination. Overall, this research provides support for a link between proneness to boredom, state orientation, and procrastination. The results are discussed in terms of self-identity and time perception.     

An investigation of hierarchical Bayes procedures in item response theory

Hierarchical Bayes procedures for the two-parameter logistic item response model were compared for estimating item and ability parameters. Simulated data sets were analyzed via two joint and two marginal Bayesian estimation procedures. The marginal Bayesian estimation procedures yielded consistently smaller root mean square differences than the joint Bayesian estimation procedures for item and ability estimates. As the sample size and test length increased, the four Bayes procedures yielded essentially the same result.The authors wish to thank the Editor and anonymous reviewers for their insightful comments and suggestions.     

A SCIENTIST AND A THEOLOGIAN SEE THE WORLD: COMPROMISE OR SYNTHESIS?

Abstract. A scientist (for whom the world is the universe) and a theologian (for whom the world is planet Earth) engage in dialogue, not contrived Platonic or Galilean dialogue, but true bidisciplinary dialogue that strives for higher viewpoint. S: Is the preservation of the human species a primary human responsibility? T: It may be a responsibility we share with God. S: The human species has a limited future if confined to the planet Earth. We must diversify our habitat by colonizing space. T: We are responsible for other life on the planet as well. The discussants conclude that besides protecting Earth ecologies, we should create new ecologies in space.     

Symbolic comparison of color similarity

This study investigated symbolic comparison of color similarity using a triplet paradigm. Results showed that the time to choose which of two color samples is more similar to a color name was a function of several measures of distance between the samples relative to the focal color for the category name. Since colors appear to be represented in memory only as names and images and not as abstract entities such as features or propositions, these results provide support for models of symbolic comparison that assume that items are stored and compared as mental analogs.     

Developmental change and the multidimensional cognitive system

The cognitive system is a multidimensional, hierarchically-structured arrangement of cognitive dimensions functionally organized into three subsystems: perceiving, conceptualizing, and symbolizing. Ontogenetic change in these subsystems is described using theoretical concepts from both multivariate developmental psychology and systems theory. Both quantitative and qualitative changes in cognitive dimensions are discussed, including a synthesis of relevant empirical research. The Gompertz equation is used to describe the general form of quantitative change throughout the life-span. The pattern oo quantitative development involves growth, stability, and decline. The pattern of qualitative development, or shifts in structural organization, also invloves three periods: divergence, parallelism, and paraller-convergence. Thus, the overall quantitative-qualitative synthesis reveals a three-phase sequence of cognitive development: divergent growth (childhood- adolescence), parallel stability (adulthood), and parallel-convergent decline (old age).