The concept of risk and responsible conduct of research

Assessment of risk is one of the key issues in the field of responsible conduct of research which covers discourses of research ethics and research integrity. The principle of minimizing risks and balancing of risks and benefits is one of the main requirements of research ethics. In addition, the content of informed consent that is another fundamental principle of research ethics derives from the assessment of risks and benefits related to a particular research project. Risk assessment also plays a crucial role in methodological design of the research project. This is an important point where research ethics and research integrity discourses overlap. Firstly, because the choice of a control group (e.g., placebo control) is a key ethical issue related to the protection of the research subjects' interests. Secondly, because the quality of the research data, that is one of the key elements of research integrity, is closely connected to the choice of research methodology as well. The problem of biased interpretation or manipulation of risk related features of biomedical research should also be taken into account. Despite the importance of the concept of risk to the field of biomedical research, its relevance has not yet attracted a sufficient attention in the responsible conduct of research debate.     

Teaching ethics: More than an honor code

An honor code is certainly a good place to start teaching engineering students about ethics, but teaching students to live honorably requires far more effort than memorizing a code of ethics statement or applying it just to academic performance. In the School of Engineering at Grand Valley State University, we have followed the model provided by the United States Military Academy at West Point. For our students this involves an introduction to the Honor Code as part of a larger Honor Concept at the very beginning of their studies and then making it an integral part of their preparation as engineers. The challenge is significant because the culture at large does not support living with an Honor Concept. This paper will begin with a discussion of the cultural context in which we must teach, because that context has changed significantly in the years since many faculty members were students themselves. The rest of the paper will detail the approach that we have taken to teach ethics as an engineer’s way of life. “The shortest and surest way to live with honor in the world is to be in reality what we would appear to be. All human virtues increase and strengthen themselves by the practice and experience of them.” Plato An earlier version of this paper was presented at the 2005 conference, Ethics and Social Responsibility in Engineering and Technology, Linking Workplace Ethics and Education, co-hosted by Gonzaga University and Loyola Marymount University, Los Angeles, CA, USA, 9–10 June 2005.     

Incremental validity of mindfulness-based attention in relation to the concurrent prediction of anxiety and depressive symptomatology and perceptions of health

This investigation evaluated the role of mindfulness-based attention in concurrently predicting anxiety and depressive symptomatology and perceived health functioning in a community sample of 170 young adults (95 females; mean age (Mage) = 22.2 years, SD = 7.6). Partially consistent with prediction, results indicated that, relative to negative and positive affectivity and emotional expression and processing associated with approach-oriented coping, mindfulness-based attention incrementally predicted anhedonic depressive, but not anxious arousal, symptoms. Additionally, consistent with prediction, mindfulness-based attention demonstrated incremental validity in relation to perceived health, and the degree of impairment of health in terms of physical and mental functioning. Results are discussed in relation to the construct development of mindfulness-based attention, and specifically, the role(s) of this factor in emotional and physical health processes.     

Event-related brain potentials elicited during word recognition by adult good and poor phonological decoders

Cognitive processing of lexical and sub-lexical stimuli was compared for good and poor adult phonological decoders. Sixteen good decoders and 16 poor decoders, average age 19 years, silently read 150 randomly computer presented sentences ending in incongruous regular, irregular, or nonwords and 100 congruent filler sentences. Electro-encephalographic recordings were made from the final word of each incongruous sentence. Although no significant group differences were found, good decoders showed specialised hemispheric word recognition processing at P200 and P300. Nonwords elicited greater N200 and P300 amplitudes for both good and poor decoders. Larger amplitude P200s were elicited by poor decoders when processing nonwords. These findings provide evidence for separable lexical and sub-lexical procedures and support a psychophysiological basis for a core phonological deficit in poor phonological decoders.     

The relationship between anxiety sensitivity and latent symptoms of emotional problems: A structural equation modeling approach

A large body of research suggests that common and specific psychopathology dimensions underlie the symptoms that occur within mood and anxiety disorders. As of yet, it is unclear precisely how the facets of Anxiety Sensitivity (AS), or fear of the symptoms of fear and anxiety, relate to these latent factors. Using data from 606 adolescents participating in the baseline phase of a longitudinal study on risk factors for emotional disorders, we modeled the facets of AS as measured by the Anxiety Sensitivity Index-Expanded Form (ASI-X) and related these facets to a hierarchical model of latent symptoms of psychological distress. Results suggest that one facet of AS is associated with a broad General Distress factor underlying symptoms of most emotional disorders while others relate to intermediate-level and conceptually-meaningful narrow factors representing aspects of psychological distress specific to particular emotional disorders.     

Whatever does not kill us: cumulative lifetime adversity, vulnerability, and resilience

Exposure to adverse life events typically predicts subsequent negative effects on mental health and well-being, such that more adversity predicts worse outcomes. However, adverse experiences may also foster subsequent resilience, with resulting advantages for mental health and well-being. In a multiyear longitudinal study of a national sample, people with a history of some lifetime adversity reported better mental health and well-being outcomes than not only people with a high history of adversity but also than people with no history of adversity. Specifically, U-shaped quadratic relationships indicated that a history of some but nonzero lifetime adversity predicted relatively lower global distress, lower self-rated functional impairment, fewer posttraumatic stress symptoms, and higher life satisfaction over time. Furthermore, people with some prior lifetime adversity were the least affected by recent adverse events. These results suggest that, in moderation, whatever does not kill us may indeed make us stronger.     

Remembering the past and imagining the future: A role for nonvisual imagery in the everyday cognition of blind and sighted people

Past research has associated depression with memory biases pertaining to the frequency, duration, and specificity of past events. Associations have been proposed between both negative and positive memory biases and depression symptoms. However, research has not examined the occurrence of actual events over time in the study of memory bias. To address these limitations and investigate whether a negative or positive memory bias is associated with symptoms of depression, we collected weekly data on specific types of life events over a 4-year period from a sample of college students, and asked students to recall event frequency at the end of that period. Exaggerated recall of frequency for positive events but not other types of events was associated with depression symptoms, using both continuous and categorical measures. Moderator analyses indicated that these effects were evidenced primarily for memories involving the self and among individuals low in trait self-enhancement. The current study indicates that positive memory-frequency bias is an important type of memory bias associated with symptoms of depression. Results support the idea that the link between memory bias for positive event frequency and depressed mood arises out of a current-self vs past-self comparison.     

Opening What Has Been Closed,Relaxing What Has Been Clenched: Dissociation and Enactment Over Time in Committed Relationships

I use dissociation and the concept of the multiple self to link Mitchell's profound insight with Goldner's critique. In the process, I use the idea of dissociation to think about the nature of different kinds of long-term relationships.