Associative retrieval processes in the human medial temporal lobe: hippocampal retrieval success and CA1 mismatch detection

Hippocampal subfields CA(3) and CA(1) are hypothesized to differentially support the generation of associative predictions and the detection of associative mismatches, respectively. Using high-resolution functional MRI, we examined hippocampal subfield activation during associative retrieval and during subsequent comparisons of memory to matching or mismatching decision probes. Activity in the dentate gyrus/CA(2/3), CA(1), and other medial temporal lobe subregions tracked associative retrieval success, whereas activity in CA(1) and the perirhinal cortex tracked the presence of associative mismatches. These data support the hypothesis that CA(1) acts as a "comparator," detecting when memory for the past and sensory input in the present diverge.     

A feel for disgust: tactile cues to pathogen presence

One function of disgust is to act as a pathogen-avoidance system preventing contact with substances harbouring disease-causing organisms. Avoiding pathogens, however, requires systems for their detection. Whereas previous research on disgust has focused on visual and olfactory detection cues, one largely overlooked modality is touch. Here we examine whether tactile cues play a role in pathogen detection and activate the disgust response. Participants briefly touched and then rated stimuli varying along dimensions predicted to correlate with pathogen presence: moisture, temperature, and consistency. Results show that participants rated wet stimuli and stimuli resembling biological consistencies as more disgusting than dry stimuli and stimuli resembling inanimate consistencies, respectively. No main effect for temperature was found. We report on predicted interactions, the relationship between disgust ratings and perceived infection risk, and individual differences. Taken together, these data suggest that touch is an important modality providing information for disgust-related processes.     

Effects of 7.5% CO(2) inhalation on allocation of spatial attention to facial cues of emotional expression

Increased vigilance to threat-related stimuli is thought to be a core cognitive feature of anxiety. We sought to investigate the cognitive impact of experimentally induced anxiety, by means of a 7.5% CO(2) challenge, which acts as an unconditioned anxiogenic stimulus, on attentional bias for positive and negative facial cues of emotional expression in the dot-probe task. In two experiments we found robust physiological and subjective effects of the CO(2) inhalation consistent with the claim that the procedure reliably induces anxiety. Data from the dot-probe task demonstrated an attentional bias to emotional facial expressions compared with neutral faces regardless of valence (happy, angry, and fearful). These attentional effects, however, were entirely inconsistent in terms of their relationship with induced anxiety. We conclude that the previously reported poor reliability of this task is the most parsimonious explanation for our conflicting findings and that future research should develop a more reliable paradigm for measuring attentional bias in this field.     

Can Nervous Nelly negotiate? How anxiety causes negotiators to make low first offers,exit early,and earn less profit

Negotiations trigger anxiety. Across four studies, we demonstrate that anxiety is harmful to negotiator performance. In our experiments, we induced either anxiety or neutral feelings and studied behavior in negotiation and continuous shrinking-pie tasks. Compared to negotiators experiencing neutral feelings, negotiators who feel anxious expect lower outcomes, make lower first offers, respond more quickly to offers, exit bargaining situations earlier, and ultimately obtain worse outcomes. The relationship between anxiety and negotiator behavior is moderated by negotiator self-efficacy; high self-efficacy mitigates the harmful effects of anxiety.     

Immunity to proactive interference is not a property of the focus of attention in working memory

The Focus of Attention (FOA) is the latest incarnation of a limited capacity store in which a small number of items, in this case four, are deemed to be readily accessible and do not need to be retrieved. Thus a corollary of these ideas is that those items in the FOA are always immune to proactive interference. While there is empirical support for instances of immunity to PI in short-term retention tasks that involve memory for four-item lists, there are also many instances in which PI is observed with four-item lists as well as instances where PI and immunity to PI can be shown in the same experiment. In contrast to the FOA assumptions, an alternative cue-based account predicts both the presence of PI and immunity to PI as a function of the relation between the cues available and the particular test. Three experiments contrasted the FOA assumptions and the cue-based approach in a short-term cued recall task in which PI is manipulated by testing whether the presentation of previous, similar items would interfere with immediate recall of three list items. The results indicated that even with very short lists, both PI and immunity to PI could be observed. The PI effects observed in our experiment are at odds with the FOA approach and are more readily explained using the cueing account.     

The overview of reviews: Unique challenges and opportunities when research syntheses are the principal elements of new integrative scholarship

In the past two decades, a new form of scholarship has appeared in which researchers present an overview of previously conducted research syntheses on the same topic. In these efforts, research syntheses are the principal units of evidence. Overviews of reviews introduce unique problems that require unique solutions. This article describes what methods overviewers have developed or have adopted from other forms of scholarship. These methods concern how to (a) define the broader problem space of an overview, (b) conduct literature searches that specifically look for research syntheses, (c) address the overlap in evidence in related reviews, (d) evaluate the quality of both primary research and research syntheses, (e) integrate the outcomes of research syntheses, especially when they produce discordant results, (f) conduct a second-order meta-analysis, and (g) present findings. The limitations of overviews are also discussed, especially with regard to the age of the included evidence. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Differential susceptibility and the early development of aggression: interactive effects of respiratory sinus arrhythmia and environmental quality

The purpose of the current study was to predict the development of aggressive behavior from young children's respiratory sinus arrhythmia (RSA) and environmental quality. In a longitudinal sample of 213 children, baseline RSA, RSA suppression in response to a film of crying babies, and a composite measure of environmental quality (incorporating socioeconomic status and marital adjustment) were measured, and parent-reported aggression was assessed from 18 to 54 months of age. Predictions based on biological sensitivity-to-context/differential susceptibility and diathesis-stress models, as well as potential moderation by child sex, were examined. The interaction of baseline RSA with environmental quality predicted the development (slope) and 54-month intercept of mothers' reports of aggression. For girls only, the interaction between baseline RSA and environmental quality predicted the 18-month intercept of fathers' reports. In general, significant negative relations between RSA and aggression were found primarily at high levels of environmental quality. In addition, we found a significant Sex × RSA interaction predicting the slope and 54-month intercept of fathers' reports of aggression, such that RSA was negatively related to aggression for boys but not for girls. Contrary to predictions, no significant main effects or interactions were found for RSA suppression. The results provide mixed but not full support for differential susceptibility theory and provide little support for the diathesis-stress model.     

Longitudinal relations among maternal behaviors, effortful control and young children's committed compliance

In a sample (n = 235) of 30-, 42-, and 54-month-olds, the relations among parenting, effortful control (EC), impulsivity, and children's committed compliance were examined. Parenting was assessed with mothers' observed sensitivity and warmth; EC was measured by mothers' and caregivers' reports, as well as a behavioral task; impulsivity was assessed by mothers' and caregivers' reports; and committed compliance was observed during a cleanup and prohibition task, as well as measured by adults' reports. Using path modeling, there was evidence that 30-month parenting predicted high EC and low impulsivity a year later when the stability of the outcomes was controlled, and there was evidence that 30- and 42-month EC, but not impulsivity, predicted higher committed compliance a year later, controlling for earlier levels of the outcomes. Moreover, 42-month EC predicted low impulsivity a year later. Fixed effects models, which are not biased by omitted time-invariant variables, also were conducted and showed that 30-month parenting still predicted EC a year later, and 42-month EC predicted later low impulsivity. Findings are discussed in terms of the importance of differentiating between effortful control and impulsivity and the potential mediating role of EC in the relations between parenting and children's committed compliance.     

Anxiety, advice, and the ability to discern: feeling anxious motivates individuals to seek and use advice

Across 8 experiments, the influence of anxiety on advice seeking and advice taking is described. Anxious individuals are found to be more likely to seek and rely on advice than are those in a neutral emotional state (Experiment 1), but this pattern of results does not generalize to other negatively valenced emotions (Experiment 2). The relationships between anxiety and advice seeking and anxiety and advice taking are mediated by self-confidence; anxiety lowers self-confidence, which increases advice seeking and reliance upon advice (Experiment 3). Although anxiety also impairs information processing, impaired information processing does not mediate the relationship between anxiety and advice taking (Experiment 4). Finally, anxious individuals are found to fail to discriminate between good and bad advice (Experiments 5a-5c), and between advice from advisors with and without a conflict of interest (Experiment 6).     

The neurogenetics of nice: receptor genes for oxytocin and vasopressin interact with threat to predict prosocial behavior

Oxytocin, vasopressin, and their receptor genes influence prosocial behavior in the laboratory and in the context of close relationships. These peptides may also promote social engagement following threat. However, the scope of their prosocial effects is unknown. We examined oxytocin receptor (OXTR) polymorphism rs53576, as well as vasopressin receptor 1a (AVPR1a) polymorphisms rs1 and rs3 in a national sample of U.S. residents (n = 348). These polymorphisms interacted with perceived threat to predict engagement in volunteer work or charitable activities and commitment to civic duty. Specifically, greater perceived threat predicted engagement in fewer charitable activities for individuals with A/A and A/G genotypes of OXTR rs53576, but not for G/G individuals. Similarly, greater perceived threat predicted lower commitment to civic duty for individuals with one or two short alleles for AVPR1a rs1, but not for individuals with only long alleles. Oxytocin, vasopressin, and their receptor genes may significantly influence prosocial behavior and may lie at the core of the caregiving behavioral system.