Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors

In the present study, we investigated the influence of bilateral intra-central amygdala (intra-CeA) microinjections of N-methyl-d-aspartate (NMDA) receptor agents on amnesia induced by a cannabinoid CB1 receptor agonist, arachydonilcyclopropylamide (ACPA). This study used a step-through inhibitory (passive) avoidance task to assess memory in adult male Wistar rats. The results showed that intra-CeA administration of ACPA (2 ng/rat) immediately after training decreased inhibitory avoidance (IA) memory consolidation as evidenced by a decrease in step-through latency on the test day, which was suggestive of drug-induced amnesia. Post-training intra-CeA microinjections of NMDA (0.0001, 0.001 and 0.01 μg/rat) did not affect IA memory consolidation. However co-administration of NMDA with ACPA (2 ng/rat) prevented the impairment of IA memory consolidation that was induced by ACPA. Although post-training intra-CeA administration of the NMDA receptor antagonist, d-(−)-2-amino-5-phosphonopentanoic acid (d-AP5; 0.01, 0.05 and 0.1 μg/rat) alone had no effect, its co-administration with an ineffective dose of ACPA (1 ng/rat) impaired IA memory consolidation. Post-training intra-CeA microinjection of an ineffective dose of d-AP5 (0.01 μg/rat) prevented an NMDA response to the impaired effect of ACPA. These results suggest that amnesia induced by intra-CeA administration of ACPA is at least partly mediated through an NMDA receptor mechanism in the Ce-A.     

Honesty–Humility and the HEXACO Structure of Religiosity and Well-Being

Past research has shown that general and intrinsic religiosity is related to higher Big Five Agreeableness, Conscientiousness and, to some extent, Extraversion. With the rise of the six-factor HEXACO (Honesty–Humility, Emotionality, eXtraversion, Agreeableness, Conscientiousness, Openness) model of personality, however, a more differentiated look at religiousness and personality is called for. It has been suggested that religiosity is more associated with Honesty–Humility than with Agreeableness. The new personality factor, Honesty–Humility has also been shown to have null or weak relations with happiness. In 5 studies involving 1375 participants from Iran, Poland, and Malaysia, the relations of Honesty–Humility and other HEXACO dimensions to religious orientation and well-being outcomes were investigated. As expected, Honesty–Humility was one of the strongest personality correlate of religiosity. Higher scores on religiousness were also associated with Agreeableness, Conscientiousness, and to some extent, Extraversion showing that the main personality characteristics of religiosity are consistent across religious contexts and personality models. Relations of Honesty–Humility to psychological well-being scales were consistently positive and stronger than its relations to subjective well-being measures, suggesting that Honesty–Humility may not be “bad” for pleasure attainment and pain avoidance, but it is definitely “good” for living a virtuous, fully functioning life.     

Effects of social influences and waiting on time judgment

Utilizing social judgment theory, the relationships of three social cues to time judgment under low physical temporal-cue conditions were explored. These social influences were as follows: being free to interact with another person, being told by the experimenter to expect to wait a specified period of time, and seeing another person's time judgment. 72 college students, randomly assigned to conditions of free social interaction (alone-interactive) and of waiting expectancy (expected-unexpected), made time estimates after 4 min., 7 sec. Each person under interactive conditions made another judgment after seeing a partner's judgment. Mean estimation was lower alone than under interactive conditions and lower under expected than unexpected waiting conditions. Under interactive conditions, correlations were positive between the individual's first and second judgments, between the partners' second judgments, and between the individual's second and the partner's first judgments. Social cues may influence time judgment.     

Sufism and Gerotranscendence: The Impact of Way of Thinking, Culture, and Aging on Spiritual Maturity

This essay examines the similarities and dissimilarities between a gerotranscendental person's and a Sufi's view of ontological questions, of self and of social and individual relationships. Using the Life History Approach followed up by thematic semi-structured interviews, I studied thirteen Iranian Sufis residing in Sweden, dividing the interviewees into two groups according to the stage of their life in which they became familiar with the Sufi ideas: those who became familiar with Sufi ideas early in their life (30 years) are called early Sufis, and those whose familiarity with Sufi ideas came about in their later life (>30) are called later Sufis. The study posits that the existence of a cosmic view of self and the surrounding world can be observed among early Sufis due to their intemalization of the Sufi ideas in early life. Regarding later Sufis, we can hypothesize that the existence of such a cosmic view is not only due to the intemalization of Sufi ideas, but also to aging.     

Substance use among Iranian psychiatric inpatients.

This study evaluated substance use among a sample of 205 psychiatric inpatients (70 women and 135 men) chosen randomly. The subjects (who had schizophrenia or mood disorders) were evaluated on a confidential questionnaire by interview. Their mean age was 35 yr. (SD= 10.4, range 16 to 69). Of these participants, 76% of the 135 men and 34% of the 70 women admitted use of substances: cigarettes (74% of men, 31.4% of women), opiates (31.9% of men, 4.3% of women), alcohol (23.7% of men, 4.3% of women), hashish (8.9% of men, no women), marijuana (3.7% of men, no women), and cocaine or LSD by none. Only 27% of the women and 63% of the men reported still using substances regularly; some reported using more than one substance. Of the current users, 61.8% of the schizophrenics, 20% of unipolar depressed, and 37.5% of bipolar patients reported current use. The reasons for substance use in order of frequencies of mention were release of tension, seeking pleasure, and need (to avoid withdrawal symptoms) by men and habit, seeking pleasure, and need by women.     

Drivers' knowledge, attitudes, and behavior: a cross-sectional study

A cross-sectional survey was conducted by random duster sampling in the city of Tehran. Knowledge of the drivers was assessed with 6 questions about national traffic laws. Attitude was assessed on a 7-item scale of drivers' perceptions. Behavior was observed by a police officer on 13 areas of assessment. Correlations were low among these three scores. Drivers with advanced education had higher scores on behavior. Knowledge, attitude, and behavior of these drivers did not seem associated.     

Religiosity, Marital Satisfaction and Child Rearing

The following research sought to examine the relationship between an individual’s performance of religious duties and its impact upon his or her level of marital satisfaction and children supervision. Findings in this connection can help strengthen families. Six hundred and sixty heterosexual couples from Tehran were studied using multistage cluster sampling. Information regarding religious duties and marital satisfaction was collected using the researcher’s prepared questionnaire, and ENRICH marital satisfaction scale. The results showed that heterosexual couples who observe religious beliefs and perform religious duties (like participation in religious rituals and ceremonies) have a higher rate of marital satisfaction, and have suitable children supervision. Thus, there is a significant correlation between performing religious duties and marital satisfaction. Considering the relation between performing religious duties and nine subscales of marital satisfaction and children supervision questionnaire, Communication Parenting and Religious Orientation account for the highest rate of performing religious duties, and Sexual Relationship accounts for the lowest rate of performing religious duties. Thus, with the increase in religiosity and performance of religious duties, marital satisfaction rate will increase, and vice versa. However, those who perform religious duties have suitable children supervision, so they have good relationship with their family. It can be concluded that religiosity develops the grounds for marital commitment and child-rearing.     

Prevalence of cigarette smoking in Iran.

The current research assessed the prevalence of cigarette smoking in Shiraz, Iran by randomly selecting 1,335 subjects (782 men and 553 women) from the city for a face-to-face interview and completion of a questionnaire. Of the participants, 205 (26%) of the men and 20 (3.6%) of the women reported being current smokers. The mean ages of smokers and nonsmokers were 41.8 and 37.0 yr., respectively (range between 16 and 90 years for smokers and nonsmokers). The mean age of starting to smoke cigarettes was 21.3 yr. (range of 10 to 60). The most common reasons for current cigarette smoking were Need to avoid withdrawal symptoms, Release of tension, and Pleasurable purposes. Foreign filter-tipped cigarettes were the most common type consumed. The mean number of cigarettes per day was 13.4 (SD = 10.3). Reports for onset of cigarette smoking included Modeling, Release of tension, and Pleasurable purposes. Cigarette smoking was reported by more males than females. The most common reason for onset of cigarette smoking was different from that for current smoking. Frequencies of smokers within age groups were varied.     

Meaning-Making Coping Among Cancer Patients in Sweden and South Korea: A Comparative Perspective

Journal of Religion and Health - The present study compared meaning-making coping among cancer patients in Sweden and South Korea, with a focus on the sociocultural context. Semi-structured...     

Analysis of Argumentation in the Discussion Sections of Published Articles in ESP Journal: A Diachronic Corpus-Based Approach

Argumentation has remained under-researched in studies analyzing academic journal publications despite its importance in academic writing. This paper reports a study in which we investigated stereotypical argumentative trends, lexico-grammatical features, and interactional metadiscourse markers in 354 research article free-standing discussion sections from the journal of ESP over forty years. The field of ESP was chosen because of its maturity, which has given substance to a dynamic ground for arguments. We drew on the pragma-dialectical approach to analyzing argumentations in the corpus. Findings indicated that due to the argumentative nature of the discussion section, certain argumentative trends recurred more often. The analysis of the lexico-grammatical features and metadiscourse markers of the standpoints also showed patterns of variability over time. The study concludes that it is imperative to incorporate relevant facets from various argumentation models to construct a comprehensive argumentation theory and gain deeper insights into argumentation in academic writing.