N-Methyl-D-aspartate receptors in the ventral tegmental area are involved in retrieval of inhibitory avoidance memory by nicotine

The interaction of opiate, cholinergic, glutamatergic and (possibly) dopaminergic inputs in the ventral tegmental area (VTA) influencing a learned behavior is certainly a topic of great interest. In the present study, the effect of intra-VTA administration of N-methyl-d-aspartate (NMDA) receptor agents on nicotine's effect in morphine state-dependent learning was investigated. An inhibitory avoidance (IA) task was used for memory assessment in male Wistar rats. Subcutaneous (s.c.) administration of morphine (5 and 7.5mg/kg) immediately after training decreased IA response on the test day, which was reinstated by pre-test administration of the same doses of the opioid; this is known as state-dependency. Moreover, pre-test administration of nicotine (0.2, 0.4 and 0.6 mg/kg, s.c.) also reversed the decrease in IA response because of post-training morphine (5mg/kg). Here, we also show that when infused into the VTA before testing, NMDA (0.01 and 0.1 microg/rat) reverse the post-training morphine effect on memory. In addition, the sub-effective doses of NMDA (0.0001 and 0.001 microg/rat) in combination with a low dose of nicotine (0.1mg/kg) which had no effects by themselves, synergistically improved retrieval of IA memory on the test day. In contrast, pre-test administration of a competitive NMDA receptor antagonist D-AP5 (0.5, 1 and 2 microg/rat) which had no effect alone prevented the nicotine reversal of morphine effect on memory. Our data indicate that NMDA receptors in the VTA are involved in the reversing effect of nicotine on morphine induced state-dependency.     

The fundamentality of existence or quiddity: a confusion between epistemology and ontology

Regarding the exhaustive discussions of the fundamentality of existence versus the fundamentality of quiddity, it is a necessary preliminary to examine and analyze the first documented statement of the fundamentality of existence. Following this, we must inquire how the concept is obtained on the basis of which such a judgment could be formed. Then we must illuminate the meaning of propositions that state only that an object is or exists (ontological propositions). Finally, by explaining the meaning of the words “quiddity” and “existence” and comparing them, indications are found of confusion between epistemological and ontological issues.

How do Iranian women from Rafsanjan conceptualize their sexual behaviors?

In Iran, women’s sexual behaviors have not been studied in detail. The aim of this study was to explore the sexual meanings generated through the lived experience of women residing in Rafsanjan, a city in the Kerman province, where interviews and focus group discussions were conducted with 51 Iranian women. Content analysis was adopted to extract the meanings and perceptions. We categorized the findings into three aspects: sexual capacity, motivation, and performance. Sexual desire was the most important concept that women used when they were referring to their sexual capacity. Marriage was the main institution in which women’s motivation for sexual relationships and encounters resided, and “the priority of men’s sexual needs and characteristics” was identified as the core principle of marriage. The concept of sexual performance was more salient and tied to the husband’s sexual initiation. Analyzing the women’s narratives revealed that women’s sexual self-understandings and their sexual behaviors are strongly determined by “androcentricity”, this being relevant both to sexuality education and reproductive health. Recognition of this issue will facilitate understanding of the cultural foundations of sexuality among Iranians and help health providers in suggesting culturally appropriate and compatible forms of health care.     

Correction to: Comparison Study of the Effects of Resistance and Endurance Exercise Interventions for the Treatment of Depression: A Meta-Analytical Review

Journal of Contemporary Psychotherapy -     

Feminist Facing up to the Logical Foundation of Dualist Philosophy: A Sequentialist Approach

Axiomathes - There is a robust tendency within the contemporary feminist mainstream to argue against and ultimately reject the so-called ‘dualising or dualist philosophy’ (associated...     

Innovative Work Behavior in Public Organizations: The Roles of Ethical and Knowledge Sharing Behaviors

Public organizations are in continuous need of innovation in their products, services, and processes in order to grow and survive. Innovative work behaviors play important role in employee innovation in these organizations. The present study aimed to test the roles of ethical and knowledge sharing behaviors on innovative work behavior in public organizations. The questionnaire consisting of 44 items was used. The data were collected from 266 participants in public organizations, and data analysis was performed through Structural Equation Modeling (SEM). According to the results, ethical behaviors had positive and significant effect on innovative work behavior, and knowledge sharing behaviors mediate the effect of ethical behavior on innovative work behaviors. The proposed model highlighted the importance of sharing mistakes and best practices in an organization to develop innovative work behavior. Furthermore, ethical behaviors were likely to be more significant predictors of innovative work behavior through knowledge sharing behaviors.     

Relationships between Self- and Peer-reported Integrative Self-knowledge and the Big Five Factors in Iran

An Integrative Self-Knowledge (ISK) Scale measures tendencies to engage in a cognitive process of uniting past, present, and desired future self-experience into a meaningful whole. In the present project, 288 Iranian university students responded to the ISK and Big Five scales and rated their dormitory roommates on these characteristics as well. These procedures most importantly revealed a positive correlation between self- and peer-reported ISK. Self-reported ISK also predicted higher levels of self-reported Extraversion, Agreeableness, Conscientiousness, Emotional Stability, and Openness to Experience, and this pattern of relationships appeared with the peer-report data as well. In these results and also in correlations of the self- with peer-report scales, associations of ISK with greater Emotional Stability and Openness to Experience were especially noteworthy. This study confirmed the validity of the ISK scale and the adaptive behavioral significance of what it measures.     

Action and coping planning with regard to dental brushing among Iranian adolescents

The aims of this study were two-fold: (i) to examine the validity of the proposed three-factor structure (intention, action-, and coping planning) in an Iranian sample of adolescents, and (ii) to assess the predictive ability of the Theory of Planned Behavior (TPB) measures of action planning and coping planning for dental brushing. Eight hundred adolescents were randomly selected to participate in the study. 90% (721) of adolescents agreed to participate. Perceived behavioral control, action and coping planning scales and a self-report questionnaire related to dental brushing behavior were completed by the adolescents at baseline. One month later (time-point 2), the adolescents were asked to reassess their frequency of dental brushing over the four week period. Data were analyzed by a confirmatory factor analysis (CFA) on an original three-factor structure (intention, action plan, and coping plan). A hierarchical linear regression analysis was also performed. The CFA for the original three-factor structure showed a good fit index (χ(2)?=?637.60, degrees of freedom df?=?116), goodness-of-fit index (GFI)?=?91, and root mean square error of approximation (RMSEA)?=?0.079. Adjusting for demographic variables, action- and coping planning together accounted for 7.9% of the variance associated with dental brushing behavior at one month. In conclusion, results suggest that action planning and coping planning are associated with higher frequency in dental brushing among Iranian adolescents.