Diurnal cycle of salivary cortisol in older adult men and women with subjective complaints of memory deficits and/or depressive symptoms: relation to cognitive functioning

In populations of young and older adults, it has been shown that individuals may be categorized into one of three diurnal subgroups when salivary cortisol levels are assessed over a 2-day period and compared for their consistency across days: a typical subgroup, a flat subgroup, and an inconsistent subgroup. Interestingly, recent studies have reported that the typical subgroup represents the majority of the young and older adult population, a finding that is difficult to reconcile with previous studies showing increased cortisol levels in older adults with depression or cognitive impairments. In order to assess whether a typical diurnal cortisol profile is representative across different subgroups of older adults, we assessed diurnal cortisol cycle representation in a sample of older adults with subjective complaints of depression and/or memory problems. Furthermore, given the robust relationship between cortisol and cognitive function, the present study examined the association between the three diurnal subgroups and cognitive performance. Forty-two older individuals were recruited on the basis of reporting subjective complaints of either memory problems and/or depressive mood. Participants were asked to sample their saliva over a 2-day period and were then asked to undergo a neuropsychological evaluation that taps into short-term memory, declarative memory and language. The results showed that 69% of the sample presented a Flat cycle of salivary cortisol over a 2-day period while 19% presented an inconsistent pattern and 12% presented a typical pattern. Participants in the flat subgroup were significantly impaired on letter verbal fluency. Furthermore, a relationship was found between diurnal cortisol subgroup representation and subjective complaint profile. These findings show that older adults with complaints of memory problems and/or depressive symptoms do not present the typical profile of the diurnal cortisol cycle, and they provide a preliminary view of how diurnal cortisol profile relates to cognitive function during human aging.     

Developmental changes in personal goal orientation from young to late adulthood: from striving for gains to maintenance and prevention of losses

Using a multimethod approach, the authors conducted 4 studies to test life span hypotheses about goal orientations across adulthood. Confirming expectations, in Studies 1 and 2 younger adults reported a primary growth orientation in their goals, whereas older adults reported a stronger orientation toward maintenance and loss prevention. Orientation toward prevention of loss correlated negatively with well-being in younger adults. In older adults, orientation toward maintenance was positively associated with well-being. Studies 3 and 4 extend findings of a self-reported shift in goal orientation to the level of behavioral choice involving cognitive and physical fitness goals. Studies 3 and 4 also examine the role of expected resource demands. The shift in goal orientation is discussed as an adaptive mechanism to manage changing opportunities and constraints across adulthood.     

Soluble interleukin 2 receptor levels, temperament and character in formerly depressed suicide attempters compared with normal controls

An imbalance of the immune system and mixed personality profiles in suicide attempters have been reported. As suicidal behavior is common in patients with psychiatric disorders within the spectrum of depressive features, in this study we measured soluble interleukin-2 receptor concentrations in plasma (sIL-2R) and investigated temperament and character profile and their potential correlation in formerly depressed patients with a history of suicide attempt. We studied sIL-2R levels in plasma and personality characteristics (using Cloninger's Temperament and Character Inventory [TCI]) of formerly depressed patients who had attempted suicide a mean of 3 years previously (n = 25), and age and gender matched normal controls (n = 25). There was no significant difference in sIL-2R levels between formerly depressed suicide attempters and age and gender matched normal controls (0.23 ng/ml +/- 0.25 vs. 0.19 ng/ml +/- 0.16). When compared to normal controls, suicide attempt patients had a significantly higher score on the temperament dimension "harm avoidance" and a lower score on the character dimension "self-directedness." No significant correlation was found between sIL-2R values and TCI dimensions. We propose that the liability to suicidal behavior among suicide attempters susceptible to depressive symptomatology may be related to high harm avoidance and low self-directedness.     

Task preparation and stimulus-evoked competition

The authors investigated how task competition evoked by a stimulus that affords both a currently relevant and a temporarily irrelevant task is affected by invalid preparation, i.e., preparation for the irrelevant task. Although invalid preparation was associated with a general performance cost, effects of stimulus-cued task competition were not enhanced on invalidly prepared trials. This result suggests that either preparation activates representations different from the ones by which stimulus cuing is mediated or that stimulus processing is postponed until invalid preparation has been corrected. In addition, invalid preparation resulted in impaired performance of the respective task when it became relevant on a subsequent trial. This result is consistent with the idea that competition due to invalid preparation is countered by task-specific inhibition.     

Psychology has to deal with efferences too

The authors argue that F. Mechsner's (2004) perceptual-cognitive approach is an important contribution to the current discussion of motor control. Mechsner presents convincing evidence against direct motor control. Nevertheless, the mechanisms by which perceptual-cognitive representations determine efferent commands must still be clarified.     

Length effect in reading and lexical decision: evidence from skilled readers and a developmental dyslexic participant

A number of experimental data have shown that naming latency increases with length for pseudo-words but not for frequent real words. Different interpretations have been proposed by current models of reading to account for such a length effect. The aim of the present study was to assess the impact of lexicality on length effect in both the reading and lexical decision tasks. For this purpose, skilled readers were asked to either name or make a lexical decision on words and pseudo-words differing in length from one to three syllables. Skilled readers' results show that length effect is modulated by lexicality in the reading task but no length effect was found in the lexical decision task. The tasks were further proposed to a well-compensated dyslexic participant who exhibited a visual attentional disorder in the absence of any associated phonological problems. A length effect on RTs was found for both words and pseudo-words in lexical decision but naming latencies were affected by length for the pseudo-words only. The present results largely conform to the predictions of the ACV98 model of reading. They are not compatible with the PDP models of reading and can only be partially accounted for by dual route models.     

The Role of Cognitive Deficits in the Development of Eating Disorders

Eating disorders (ED), including anorexia and bulimia nervosa, are chronic illnesses with periods of symptom exacerbation and remission. Because symptoms are usually present from 6 to 24 months before a diagnosis is made, aetiological agents are believed to be active well before symptoms appear. It is proposed that neuropsychological deficits in various cognitive domains preexist and underlie the aetiology of ED. This paper provides a comprehensive review of the literature relevant to neuropsychological deficits in ED patients and explores the relationship between cognitive deficits, psychosocial development, and the development of ED. Although the role of neuropsychological deficits in the evolution of ED requires further research, the proposed association has significant implications for clinical practice.     

Mental health professionals' attitudes towards people who are deaf

Mental health professionals' attitudes towards deaf people were examined in relation to their previous contact with deaf people and their knowledge of deafness. Data were gathered regarding different aspects of contact, including the number and type of relationships participants had had with deaf people. A cognitive-processing theory of attitude change following contact (Rothbart & John, 1985) was explored. Knowledge of deafness did not correlate with attitudes towards deaf people but a relationship was found between the amount of contact that professionals had with deaf people of equal or higher status and more positive attitudes.     

Nature, Nurture, and Individual Differences in Early Understanding of Mind

The ability to understand other minds is a dramatic development that enables children to adapt to their social worlds. In this first genetic analysis of the phenomenon, using 119 same-sex 3-year-old twin pairs, evidence for substantial genetic influence was found. Intraclass correlations for identical and fraternal twins were .66 and .32, respectively; the maximum-likelihoodmodel-fitting estimate of heritability was 67%. Bivariate model-fitting analyses showed that most (66%) of this genetic influence on understanding of mind was independent of verbal ability. Environmental influences on understanding of mind were attributed to child-specific factors,rather than those shared by children in the same family.     

Syntactic priming in written production: Evidence for rapid decay

There is strong evidence for syntactic priming in language production (Bock, 1986), but little evidence about the time course of such effects. We report an experiment that examined the circumstances under which syntactic priming decays in written language production. Participants completed sentence fragments that allowed completions with one of two syntactic forms (Pickering & Branigan, 1998). They tended to produce the same syntactic form for immediately consecutive fragments, even though the two fragments described different events. However, when the experimental fragments were separated by other fragments with unrelated syntactic forms, this tendency rapidly diminished. The results suggest that priming effects in written production decay rapidly when other structures are subsequently produced. We discuss the implications for the application of syntactic information during production.