Influence of properties of layered silicate minerals on adsorbed DNA surface affinity,self-assembly and nanopatterning

We report on the specific interaction between DNA and some mica-family minerals and other layered silicate structures. The interaction depends on mineral surface's crystallography, chemistry and potential. These properties are responsible for a remarkable variety of adsorption mechanisms and can be used to modulate surface self-assembly and nanopatterning of DNA. The controlled deposition of DNA onto non-conductive mineral regions with atomically flat boundaries has very attractive applications in nano-biotechnology (for example, microelectronics, microarrays and sensors). In addition, the extreme affinity discovered for some mineral surfaces, together with their ability to organize the DNA molecules, could be an indication of their catalytic potential. It may also have had relevance in the prebiotic environment, with important implications for the earth and life sciences.     

A Compelling Practice: Empowering Future Leaders in the Medical Humanities

Medical students and faculty explore the medical humanities for diverse reasons: as a medium for self-reflection, a means to cultivate professionalism and humanism, and a way to gain an appreciation for the broader contexts in which illness and health occur. One important area for development is increasing the exposure of learners and clinicians of various levels of training to the medical humanities and to role models in the field. Student-led programs in the medical humanities at the American Medical Student Association (AMSA) address these needs by offering unique opportunities for learning and sharing experiences. AMSA programs connect physicians-in-training using technology to create virtual communication and learning opportunities. These include monthly book discussion webinars, the Writers' Institute and the Medical Humanities Scholars Program (MHSP).     

Social Networking Sites: Mediating the Self and its Communities

What do social networking sites reveal about the relation between the self and the community? We conceptualise social networking sites as technologies of the self and the community enabling individuals to self‐present and also objectifying the community's evaluation of individuals (through ‘structures of recognition’ such as page views, friends and lovehearts). We analyse the way in which 37 Scottish adolescents used the social networking site Bebo in nonprescribed and creative ways. First, they challenged the single authorship of profiles by co‐creating multi‐authored profiles. Second, they used creative language to obscure meaning from the preying eyes of parents, teachers and potential employers. We conclude by discussing the simplistic assumptions that Bebo makes about the relation between the self and the community. In contrast, newer social networking sites such as Facebook and Google+ are increasingly enabling people to present different facets of themselves to different communities. How people use social networking sites, and how these sites are developing to attract more users, reveals how the multiplicity of human identity is related to the multiple communities that people participate in. Copyright © 2013 John Wiley & Sons, Ltd.     

The Psychoanalytic Study of the Child,Volume VI Edited by Ruth S. Eissler,Anna Freud,Heinz Hartmann,Ernst Kris

Abstract

The effect of affective group bibliotherapy (GB) was compared to affective group therapy (GT) on patients’ functioning in therapy and their session impression. Three small groups totaling twenty–five in–patients in a hospital in Israel participated in the study. Clients concurrently participated in both group types, undergoing three sessions in each condition. In–therapy behaviors were assessed through the Client Behavior System (CBS; Hill &; O’Brien, 1999). Results indicated that in the GB condition compared to the GT condition, clients showed less resistance, used simple responses less frequently, and expressed greater affective exploration. The Session Evaluation Questionnaire (SEQ; Stiles et al., 1994) was used to measure clients’ impressions of the sessions. Results indicated that patients evaluated the two treatment conditions equally. Overall, the results support earlier findings, suggesting that affective bibliotherapy can be an effective method of treatment.     

The Question of Higher Education for the Blind

Building on the theory of reasoned action (I. Ajzen & M. Fishbein, 1973, 1980; M. Fishbein & I. Ajzen, 1975) and expectancy theory, the authors examined the mediating role of alcohol expectancies in adolescent drinking behaviors by testing whether alcohol expectancy outcomes and valuations (the extent to which these outcomes are perceived as good or bad) mediate the association between peer influences and lifetime alcohol use. Early adolescents (N = 904) from 2 public middle schools in western Michigan completed a battery of questionnaires. Overall, results showed that alcohol expectancies and valuations partially mediated the relations between peer influences (peer use and peer approval) and lifetime alcohol use. The findings suggest that associating with peers who are perceived as using alcohol and approving of drinking may influence adolescents’ alcohol expectancies. The authors briefly discuss future research directions and implications for prevention.     

The Effects of Subject-and Experimenter-Induced Defensive Response Sets on Picture-Frustration Test Reactions

Thirty male college students, half scoring high and half low on the MMPI K-scale, were administered a multiple-choice (M-C) modification of the Rosenzweig P-F Study under three instructional sets. Two of these sets were induced by E and compared with the third which represented S's normal test-taking set. The two induced sets included (1) a “should” set in which concern for the social consequences of behavior was accentuated, and (2) a “wish” set in which concern for social consequences was minimized, and freedom of self-expression was accentuated.

It was hypothesized that Ss making extremely high or low scores on the K-scale would likewise score differently on the M-C, P-F test. High K, defined by its authors as a measure of test defensiveness, and low K, as test-taking candidness, would be associated with P-F score patterns reflecting these test-taking attitudes: High K Ss showing Impunitive (M) dominant reaction patterns and low K showing Extrapunitive (E) or Intropunitive (I) dominant patterns. These hypothèses were confirmed except that intropunitive responses were extremely rare in the entire subject sample.

It was further hypothesized that the typical high K pattern would be induced in low K Ss under the “should” instructional set and the low K pattern would be elicited from high K Ss under “wish” instructions. This expectation was confirmed. It was suggested that the technique of manipulating responses via test taking instructions can generate correction factors useful in projective as well as structured personality tests.     

The Number of Distinct Basic Values and Their Structure Assessed by PVQ–40

Sixty-eight outpatients from a veterans' administration psychiatry clinic and community mental health center were assessed with 3 measures of depressive personality disorder (DPD)-the Diagnostic Interview for Depressive Personality Disorder (Gunderson, Phillips, Triebwasser, &; Hirschfeld, 1994), the Depressive Personality Disorder Inventory (Huprich, Margrett, Barthelemy, &; Fine, 1996), and the Structured Clinical Interview for DSM-IV Axis II Disorders (First, Gibbon, Spitzer, Williams, &; Benjamin, 1997a)-to evaluate their convergent and discriminant validity. Evidence supporting the measures' validity was mixed. The rate of convergence of depressive personality diagnoses across 3 measures was less than optimal, but the degree of intercorrelation among the measures was strong. Although depressive personality scores had moderate levels of intercorrelations with other personality disorders, the degree of intercorrelation decreased substantially after controlling for depressive symptoms. I conclude that further work is needed to strengthen the validity of measures of DPD.