Preferences Regarding Targeted Education and Risk Assessment in People with a Family History of Major Depressive Disorder

Genetic testing for susceptibility to major depressive disorder (MDD) is not available for clinical use at present. Given this, family history remains the best predictor for development of MDD, and family-history-based risk assessment and information about familial aspects of MDD may be useful to clients at increased risk for MDD attending for genetic counseling. This study uses a mixed-methods design to assess the information needs and preferences of people at increased familial risk for MDD. Telephone interviews were conducted with 23 individuals, who had at least one first-degree relative with MDD and were recruited through advertisements placed on depression education websites. The most preferred way to access depression information was via the internet (87 % of participants), although this preference may have been due to the internet-based recruitment method. The second most preferred dissemination strategy (56 %) was face-to-face delivery through a health professional, including genetic counselors. Individuals reported a need for information about etiology and development of MDD, reproductive decision-making, early detection of symptoms and risk-reducing strategies. Nearly all participants expressed an interest in risk assessment. The present study found evidence of a high level of interest for information targeted to people at increased familial risk for MDD. Genetic counselors are likely to be called upon increasingly to provide supportive counseling to assist clients at increased familial risk in interpreting and contextualizing such information once it becomes available.     

On Some Properties of Humanly Known and Humanly Knowable Mathematics

We argue that the set of humanly known mathematical truths (at any given moment in human history) is finite and so recursive. But if so, then given various fundamental results in mathematical logic and the theory of computation (such as Craig’s in J Symb Log 18(1): 30–32(1953) theorem), the set of humanly known mathematical truths is axiomatizable. Furthermore, given Godel’s (Monash Math Phys 38: 173–198, 1931) First Incompleteness Theorem, then (at any given moment in human history) humanly known mathematics must be either inconsistent or incomplete. Moreover, since humanly known mathematics is axiomatizable, it can be the output of a Turing machine. We then argue that any given mathematical claim that we could possibly know could be the output of a Turing machine, at least in principle. So the Lucas-Penrose (Lucas in Philosophy 36:112–127, 1961; Penrose, in The Emperor’s new mind. Oxford University Press, Oxford (1994)) argument cannot be sound.     

Orders to Shoot (a Camera): Effects of Ostracism on Obedience

Research suggests that ostracism increases susceptibility to indirect forms of social influence (e.g., conformity). Yet, no study to date has explored whether the effects of ostracism extend to the most direct form of social influence—obedience. We investigated whether ostracized individuals would be more likely to obey a direct command to do something effortful in uncomfortable conditions. Participants (N = 62) were randomly assigned to be included or ostracized in Cyberball, or assigned to a control condition. They were then approached by the experimenter and commanded to go outside when temperatures were below 30°F and take 39 unique and creative photographs in the cold of winter. Ostracized participants were more likely to obey the experimenter’s command to be creative when taking photographs. No differences in obedience emerged between the inclusion and the control condition. We provided evidence completing the social influence “trifecta”: ostracism increases susceptibility to conformity, compliance, and now, obedience.     

A Systematic Review of Ethnoracial Representation and Cultural Adaptation of Mindfulness- and Meditation-Based Interventions

Several factors may impede ethnoracial minority inclusion in Mindfulness- and Meditation-Based Intervention (MMBI) studies, such as healthcare disparities, historical underrepresentation in clinical research, and a conceptual perspective that emphasizes the universality of Buddhist teachings. This systematic review was performed with the aim of describing MMBI studies with a significant diversity focus, defined as involving minority inclusion in sample composition, cultural adaptations of interventions, and/or planned comparisons of outcomes for different ethnoracial groups. Studies were identified through PsycINFO and MEDLINE databases from 1990 to 2016 in the United States. We reviewed 12,265 citations to include 24 MMBI diversity-focused studies. Aside from Native Alaskans, all other major US ethnoracial minority groups were included in at least one study. Most of the studies (75%) were conducted with child and youth samples; the others included only women. Most (58%) included participants selected for a health or mental health condition, but none required specific diagnoses for study inclusion. The most commonly used MMBI was mindfulness-based stress reduction (29%), and only 12.5% of all studies used a culturally adapted intervention. Only one study reported planned ethnoracial comparisons of treatment outcomes. Cohen’s d effect sizes for single-sample studies ranged from 0.10 to 0.62 and for randomized controlled trials ranged from 0.02 to 0.99. Results from this systematic review highlight the dearth of diversity focus in MMBI research. Future work should include indicators of feasibility, acceptability, and safety; address underrepresentation of ethnoracial minorities, men, and participants with clinically or functionally significant symptoms; and investigate cultural adaptations to optimize treatment effectiveness.     

Profiles of Contextual Risk at Birth and Adolescent Substance Use

This study examined whether there are subgroups of families with distinct profiles of prenatal/birth contextual risk, and whether subgroup membership was differentially related to adolescent substance use. Data from the Northern Finland Birth Cohort 1986 were used. A five-class model provided the most meaningful solution. Large Family Size (7.72%) and Low Risk (69.69%) groups had the lowest levels of alcohol, cigarette, and illegal drug use. Similar high levels for each of the three substance-related outcomes were found for Parent Substance Misuse (11.20%), Maternal School Dropout (4.66%), and Socioeconomic Disadvantage (6.72%) groups. Maternal smoking and drinking while pregnant and paternal heavy alcohol use were found to be key prenatal risk factors that tended to cluster together and co-occur with other prenatal risk factors differently for different subgroups of youth.     

Goodness Beyond Speech

The article addresses Raimond Gaita's attempt to construe the ethical in terms of a notion of speech that is tied to presence (each of us, he holds, is called to become someone ‘authentically present in speech and deed’ ( Gaita 1991 , p. 145)), a notion through which he articulates a sense both of human uniqueness – speech demands that one find one's own words – and of human fellowship: to find one's words is to achieve the depth that enables one to be taken seriously by others. The article argues, however, that the notion of speech is caught in a double bind; for it requires a spontaneity that is incompatible with the self‐presence that it also requires. In a way that Gaita cannot acknowledge, goodness is beyond speech.