Executive dysfunction affects word list recall performance: Evidence from amyotrophic lateral sclerosis and other neurodegenerative diseases

The Rey Auditory Verbal Learning Test (RAVLT) is widely used in clinical practice to evaluate verbal episodic memory. While there is evidence that RAVLT performance can be influenced by executive dysfunction, the way executive disorders affect the serial position curve (SPC) has not been yet explored. To this aim, we analysed immediate and delayed recall performances of 13 non‐demented amyotrophic lateral sclerosis (ALS) patients with a specific mild executive dysfunction (ALSci) and compared their performances to those of 48 healthy controls (HC) and 13 cognitively normal patients with ALS. Moreover, to control for the impact of a severe dysexecutive syndrome and a genuine episodic memory deficit on the SPC, we enrolled 15 patients with a diagnosis of behavioural variant of frontotemporal dementia (bvFTD) and 18 patients with probable Alzheimer's disease (AD). Results documented that, compared to cognitively normal subjects, ALSci patients had a selective mid‐list impairment for immediate recall scores. The bvFTD group obtained low performances with a selectively increased forgetting rate for terminal items, whereas the AD group showed a disproportionately large memory loss on the primary and middle part of the SPC for immediate recall scores and were severely impaired in the delayed recall trial. These results suggested that subtle executive dysfunctions might influence the recall of mid‐list items, possibly reflecting deficiency in control strategies at retrieval of word lists, whereas severer dysexecutive syndrome might also affect the recall of terminal items possibly due to attention deficit or retroactive interference.     

Neural substrates of the ‘low‐level’ system for speech articulation: Evidence from primary opercular syndrome

We describe a patient with progressive disorder of speech, without language impairment (opercular syndrome). Morphometric analysis confirmed asymmetric volume reduction of the precentral areas (>left). Diffusion imaging showed significant white matter changes in the left frontal lobe, with specific involvement of the left corticobulbar tract and connections between supplementary/pre‐supplementary motor areas and the frontal operculum (frontal aslant tract). We suggest that the organization of expressive language includes a ‘low level’ motor system principally distributed in the left hemisphere that shows specific susceptibility to neurodegeneration, distinct from neural systems subtending praxic, and cognitive aspects of language.     

Analogous selection processes in declarative and procedural working memory: N-2 list-repetition and task-repetition costs

Working memory (WM) holds and manipulates representations for ongoing cognition. Oberauer (Psychology of Learning and Motivation, 51, 45–100, 2009) distinguishes between two analogous WM sub-systems: a declarative WM which handles the objects of thought, and a procedural WM which handles the representations of (cognitive) actions. Here, we assessed whether analogous effects are observed when participants switch between memory sets (declarative representations) and when they switch between task sets (procedural representations). One mechanism assumed to facilitate switching in procedural WM is the inhibition of previously used, but currently irrelevant task sets, as indexed by n-2 task-repetition costs (Mayr & Keele, Journal of Experimental Psychology: General, 129(1), 4–26, 2000). In this study we tested for an analogous effect in declarative WM. We assessed the evidence for n-2 list-repetition costs across eight experiments in which participants switched between memory lists to perform speeded classifications, mental arithmetic, or a local recognition test. N-2 list-repetition costs were obtained consistently in conditions assumed to increase interference between memory lists, and when lists formed chunks in long-term memory. Further analyses across experiments revealed a substantial contribution of episodic memory to n-2 list-repetition costs, thereby questioning the interpretation of n-2 repetition costs as reflecting inhibition. We reanalyzed the data of eight task-switching experiments, and observed that episodic memory also contributes to n-2 task-repetition costs. Taken together, these results show analogous processing principles in declarative and procedural WM, and question the relevance of inhibitory processes for efficient switching between mental sets.     

Emotions associated with counterfactual comparisons drive decision-making in Footbridge-type moral dilemmas

Based on the dual-process theory of moral judgment, it has been suggested that in Footbridge-type dilemmas the anticipation of the emotional consequences of causing intentional harm might contribute to the decision of rejecting utilitarian resolutions. However, no empirical data have been reported on the emotions felt by participants after their decisions, and the role played by emotions in Trolley-type dilemmas remains to be determined. The present study investigated the specific emotions engaged both after decision choices and after the generation of the counterfactual scenario in Trolley- and Footbridge-type dilemmas. The results support the idea that in Footbridge-type dilemmas decision-making is driven by the attempt to minimize the aversive emotional state evoked by the decision outcome. A greater increase in emotional intensity was found overall for Footbridge-type than Trolley-type dilemmas after the counterfactual generation following typical (non-utilitarian) choices, with guilt, regret, and shame being the emotions that increased most. Critically, in Footbridge-type dilemmas only, typical choices were predicted by the increase in regret intensity experienced after counterfactual generation.     

Re-conceptualizing Self,Speaker, and Body: Applying an Enactive and Conversation Analytic Approach to Selfhood and Cognition

In this article I review significant contributions to the subfield of Embodied Cognition that formulate an inclusive account of the body's role in cognitive processes. I argue that a reconceptualization of the mind–body problem must take into account some notion of the self as a nonlocalized, transient phenomenon that emerges through day-to-day interaction. Drawing on literature from epistemology, phenomenology, and Conversation Analysis, I aim to revise contributions that rely on essentialized notions of the self and speaker, in terms of an enactive and Conversation Analytic approach to selfhood and cognition.     

Planting the seeds of change: Directionality in the narrative construction of recovery from addiction

Objective: The dominant theoretical perspective that guides treatment evaluations in addiction assumes linearity in the relationship between treatment and outcomes, viewing behaviour change as a ‘before and after event’. In this study we aim to examine how the direction of the trajectory of the process from addiction to recovery is constructed in personal narratives of active and recovering users.

Design: 21 life stories from individuals at different stages of recovery and active use were collected and analysed following the principles of narrative analysis.

Results: Personal trajectories were constructed in discontinuous, non-linear and long lasting patterns of repeated, and interchangeable, episodes of relapse and abstinence. Relapse appeared to be described as an integral part of a learning process through which knowledge leading to recovery was gradually obtained.

Conclusion: The findings show that long-term recovery is represented as being preceded by periods of discontinuity before change is stabilised. Such periods are presented to be lasting longer than most short-term pre-post intervention designs can capture and suggest the need to rethink how change is defined and measured.     

Body Dissatisfaction in College Women and Their Mothers: Cohort Effects, Developmental Effects, and the Influences of Body Size, Sexism, and the Thin Body Ideal

A study of body dissatisfaction, as measured by the Figure Rating Scale (Stunkard, Sorenson, & Schlusinger, 1983) and the Body Esteem Scale (Franzoi & Shields, 1984), in 75 college women and their mothers indicated that both daughters and mothers experienced body dissatisfaction. When body size was statistically controlled, either no difference was found between the groups or daughters were found to have greater body dissatisfaction than mothers. The results supported the hypotheses that (1) there are generational differences in body dissatisfaction, (2) both cohort and developmental effects contribute to these differences, and (3) that a developmental effect (mothers' greater body size) may obscure a cohort effect (daughters' greater exposure to the thin body ideal). Body dissatisfaction measures based on the mothers' retrospective ratings of how they felt at their daughters' age were consistent with these hypotheses. Relationships between body dissatisfaction and the Sociocultural Attitudes Toward Appearance Questionnaire (Heinberg, Thompson, & Stormer, 1995) were stronger and more frequent for daughters than for mothers and for the Internalization Scale than for the Awareness Scale. Relationships between the Ambivalent Sexism Inventory (Glick & Fiske, 2001) and body dissatisfaction were stronger for mothers than for daughters and for Benevolent Sexism than for Hostile Sexism.     

Need for cognitive closure and politics: Voting,political attitudes and attributional style

T his paper examines the impact of dispositional Need for Cognitive Closure (NFC) on different political attitudes and on the “person blame” and the “system blame” dimensions. Two hundred and thirty‐four psychology students completed a questionnaire containing the Italian version of the Need for Closure scale, a measure of political and ideological attitudes, a measure of the person‐system blame dimensions, and a measure of past voting. Results showed that high NFC individuals (vs. low NFCs) reported having voted for a right‐wing party and holding more conservative attitudes. High NFCs (vs. low NFCs) turned out to have stronger anti‐immigrant attitudes, to be more nationalistic, to prefer an autocratic leadership and a centralized form of political power. High NFCs also value religiosity more highly than low NFCs. High NFCs (vs. low NFCs) scored lower on pluralism and multiculturalism. Furthermore, high NFCs (vs. low NFCs) revealed a tendency to blame individuals for social problems, but no significant difference was found with regard to the system blame dimension. Results are discussed in the light of the motivated social cognition approach (Jost, Glaser, Kruglanski, & Sulloway, 2003).     

Impaired awareness of movement disorders in Parkinson’s disease

Background

This study analyzed the presence of awareness of movement disorders (dyskinesias and hypokinesias) in 25 patients with Parkinson’s disease (PD) and motor fluctuations (dyskinesias, wearing off, on–off fluctuations). Of the few studies that have dealt with this topic, none have analyzed the differences in the awareness of motor deficits by comparing the on and off states using motor scales and an extensive battery of tests to assess cognitive and behavioral functioning.

Methods

PD patients were compared on three different scales that we have devised to measure awareness of movement disorders: Global Awareness of Movement (GAM) Disorders, dyskinesia/hypo-bradykinesia rating scales.

Results

Data showed that PD patients had greater awareness and psychological suffering in the off state than in the on state. In particular, they were troubled by motor disabilities related to hypokinesias and had mood-related symptoms and a perception of disability in activities of daily living. Interestingly, patients only showed a selective reduction of awareness of movement disorders associated with executive functions and related to dyskinesias in the on state, compared to a preserved awareness of hypokinesias in the off state. On the contrary, no association with executive functions was found in the off state.

Conclusion

Our findings suggest that the dopaminergic overstimulation of mesocorticolimbic pathways may cause a dysfunction of prefrontal–subcortical connections related to the impaired insight.