Role of TRPV1 in consolidation of fear memories depends on the averseness of the conditioning procedure

Despite the fact that TRPV1 receptors are widely expressed in brain structures such as the hippocampus, its functions remain largely unknown. In the present study, we have investigated the possible modulatory role of the hippocampal endovanilloid system upon memory consolidation of two different behavioral tasks in rats. Post-training infusion of the TRPV1 antagonist capsazepine disrupted memory consolidation with a strong training protocol, but not with a weak one in the contextual fear conditioning or in the step-down inhibitory avoidance task. These results provide evidence that the modulation of the hippocampal memory consolidation through TRPV1 receptors takes place only in presence of a strong emotional experience, suggesting that a certain aversiveness level is required in order to recruit endovanilloids to exert this function. A possible synergic role of hippocampal endovanilloid and endocannabinoid system on memory consolidation is discussed.     

Fitting a Thurstonian IRT model to forced-choice data using Mplus

To counter response distortions associated with the use of rating scales (a.k.a. Likert scales), items can be presented in a comparative fashion, so that respondents are asked to rank the items within blocks (forced-choice format). However, classical scoring procedures for these forced-choice designs lead to ipsative data, which presents psychometric challenges that are well described in the literature. Recently, Brown and Maydeu-Olivares (Educational and Psychological Measurement 71: 460–502, 2011a) introduced a model based on Thurstone’s law of comparative judgment, which overcomes the problems of ipsative data. Here, we provide a step-by-step tutorial for coding forced-choice responses, specifying a Thurstonian item response theory model that is appropriate for the design used, assessing the model’s fit, and scoring individuals on psychological attributes. Estimation and scoring is performed using Mplus, and a very straightforward Excel macro is provided that writes full Mplus input files for any forced-choice design. Armed with these tools, using a forced-choice design is now as easy as using ratings.     

The adaptation of the Affective Norms for English Words (ANEW) for European Portuguese

This study presents the adaptation of the Affective Norms for English Words (ANEW; Bradley & Lang, 1999a) for European Portuguese (EP). The EP adaptation of the ANEW was based on the affective ratings made by 958 college students who were EP native speakers. Subjects assessed about 60 words by considering the affective dimensions of valence, arousal, and dominance, using the Self-Assessment Manikin (SAM) in either a paper-and-pencil or a Web survey procedure. Results of the adaptation of the ANEW for EP are presented. Furthermore, the differences between EP, American (Bradley & Lang, 1999a), and Spanish (Redondo, Fraga, Padrón, & Comesa?a, Behavior Research Methods, 39, 600–605, 2007) standardizations were explored. Results showed that the ANEW words were understood in a similar way by EP, American, and Spanish subjects, although some sex and cross-cultural differences were observed. The EP adaptation of the ANEW is shown to be a valid and useful tool that will allow researchers to control and/or manipulate the affective properties of stimuli, as well as to develop cross-linguistic studies. The normative values of EP adaptation of the ANEW can be downloaded at .     

Efectos diferenciales de la frecuencia silábica: dependencia del tipo de prueba y características de los estímulos

Resumen

La frecuencia silábica posicional es una variable de reciente utilización en nuestro idioma. Por su carácter fonológico ha sido utilizada en este trabajo tanto para estudiar su papel en la lectura como para obtener algunas pistas sobre diferencias interlingüísticas entre nuestro idioma y otros que como el inglÉs son más opacos a la hora de traducir a sonidos su ortografía. Se utilizaron dos tipos de pruebas: decisión lÉxica y lectura que presumiblemente implican diferentes demandas cognitivas. Los resultados de la tarea de decisión lÉxica (Experimentos 1 y 3) muestran, en general, que la frecuencia silábica enlentece la respuesta del sujeto tanto en las palabras como en las pseudopalabras, confirmando algunos estudios previos (De Vega et al., 1990). Por el contrario, en la tarea de lectura (Experimentos 2 y 4) la frecuencia silábica tiende a acelerar la respuesta en la mayoría de los estímulos. Este comportamiento diferencial de los sujetos en función de la tÉcnica utilizada sugiere que mientras la decisión lÉxica exige el ascenso hasta el nivel de palabra, la lectura puede realizarse con Éxito desde un nivel prelÉxico silábico.     

Emotional distraction in boys with ADHD: Neural and behavioral correlates

Although, in everyday life, patients with attention deficit hyperactivity disorder (ADHD) are frequently distracted by goal-irrelevant affective stimuli, little is known about the neural and behavioral substrates underlying this emotional distractibility. Because some of the most important brain responses associated with the sudden onset of an emotional distracter are characterized by their early latency onset and short duration, we addressed this issue by using a temporally agile neural signal capable of detecting and distinguishing them. Specifically, scalp event-related potentials (ERPs) were recorded while 20 boys with ADHD combined type and 20 healthy comparison subjects performed a digit categorization task during the presentation of three types of irrelevant, distracting stimuli: arousing negative (A−), neutral (N) and arousing positive (A+). Behavioral data showed that emotional distracters (both A− and A+) were associated with longer reaction times than neutral ones in the ADHD group, whereas no differences were found in the control group. ERP data revealed that, compared with control subjects, boys with ADHD showed larger anterior N2 amplitudes for emotional than for neutral distracters. Furthermore, regression analyses between ERP data and subjects’ emotional ratings of distracting stimuli showed that only in the ADHD group, emotional arousal (ranging from calming to arousing) was associated with anterior N2: its amplitude increased as the arousal content of the visual distracter increased. These results suggest that boys with ADHD are more vulnerable to the distracting effects of irrelevant emotional stimuli than control subjects. The present study provides first data on the neural substrates underlying emotional distractibility in ADHD.     

Identification and Small Sample Estimation of Thurstone's Unrestricted Model for Paired Comparisons Data

The interpretation of a Thurstonian model for paired comparisons where the utilities' covariance matrix is unrestricted proved to be difficult due to the comparative nature of the data. We show that under a suitable constraint the utilities' correlation matrix can be estimated, yielding a readily interpretable solution. This set of identification constraints can recover any true utilities' covariance matrix, but it is not unique. Indeed, we show how to transform the estimated correlation matrix into alternative correlation matrices that are equally consistent with the data but may be more consistent with substantive theory. Also, we show how researchers can investigate the sample size needed to estimate a particular model by exploiting the simulation capabilities of a popular structural equation modeling statistical package.     

Post-Traumatic Stress Disorder,Sensory Integration,and Aquatic Therapy: A Scoping Review

The prevalence of post-traumatic stress disorder (PTSD) continues to increase. Symptomology of PTSD include sensory deficits much like those displayed in children with sensory integration (SI) disorder. The aim of this scoping review is to review symptoms of PTSD and SI, and make a case of how aquatic therapy may be an effective modality in treating clients with PTSD. Eighteen articles were selected for review. From this review, it is suggested that aquatic therapy can be an effective modality in reducing symptoms of PTSD; however, future research is essential in determining its effectiveness.     

Social information processing in preschool children: Relations to sociodemographic risk and problem behavior

Using a multicomponent, process-oriented approach, the links between social information processing during the preschool years and (a) sociodemographic risk and (b) behavior problems in preschool were examined in a community sample of 196 children. Findings provided support for our initial hypotheses that aspects of social information processing in preschool are related to both sociodemographic risk and behavior problems in preschool. Response evaluation and in particular the positive evaluation of an aggressive response were related to both sociodemographic risk and children’s aggressive behavior and partially mediated the links between sociodemographic risk and aggressive behavior in preschool.     

The role of robotic modelling in cognitive science

From the perspective of cognitive robotics, this paper presents a modern interpretation of Newell’s (1973) reasoning and suggestions for why and how cognitive psychologists should develop models of cognitive phenomena. We argue that the shortcomings of current cognitive modelling approaches are due in significant part to a lack of exactly the kind of integration required for the development of embodied autonomous robotics. Moreover we suggest that considerations of embodiment, situatedness, and autonomy, intrinsic to cognitive robotics, provide an appropriate basis for the integration and theoretic cumulation that Newell argued was necessary for psychology to mature. From this perspective we analyse the role of embodiment and modes of situatedness in terms of integration, cognition, emotion, and autonomy. Four complementary perspectives on embodied and situated cognitive science are considered in terms of their potential to contribute to cognitive robotics, cognitive science, and psychological theorizing: minimal cognition and organization, enactive perception and sensorimotor contingency, homeostasis and emotion, and social embedding. In combination these perspectives provide a framework for cognitive robotics, not only wholly compatible with the original aims of cognitive modelling, but as a more appropriate methodology than those currently in common use within psychology.