Cognitive deficits in relation to personality type and hypothalamic-pituitary-adrenal (HPA) axis dysfunction in women with stress-related exhaustion

Exhaustion caused by long-term work-related stress may cause cognitive dysfunction. We explored factors that may link chronic stress and cognitive impairment. Personality, psychiatric screening, and behavior were assessed by self-reporting measures in 20 female patients (mean age 39.3 years; range 26-53) with a preliminary diagnosis of stress-related exhaustion and in 16 healthy matched controls. Cognitive performance was investigated with a detailed neuropsychological test battery. Cortisol axis function was assessed by urinary and saliva collections of cortisol, dexamethasone suppression, Synacthen response, and corticotropin-releasing hormone (CRH) tests. Proinflammatory cytokines were measured. Hippocampal volumes were estimated by magnetic resonance imaging. Multivariate and univariate statistical methods were used to explore putative differences between groups and factors linked to cognitive impairment. Cognitive function clearly differed between groups, with decreased attention and visuospatial memory in the patient group, suggesting frontal cortex/medial temporal cortex-network dysfunction. Increased harm avoidance and persistence was present among patients, with lowered self-directedness linked to lower quality of life, increased anxious and depressive tendencies, and experiences of psychosocial stress. Attention was decreased with concomitantly impaired visuospatial memory. The pituitary (adrenocorticotropic hormone, ACTH) response to CRH was decreased in patients, with an increased cortisol/ACTH response to CRH. However, cortisol production rates, diurnal or dexamethasone-suppressed saliva cortisol levels, and the cortisol response to Synacthen were unaltered. Hippocampal volumes did not differ between groups. These findings suggest that cognitive dysfunction in stress-related exhaustion is linked to distinct personality traits, low quality of life, and a decreased ACTH response to CRH.     

Sex Differences in Episodic Memory

ABSTRACT— Research shows sex differences in episodic memory. These differences vary in magnitude as a function of the type of material to be remembered. Throughout the life span, verbal episodic-memory tasks yield differences favoring women. In contrast, episodic-memory tasks requiring visuospatial processing result in differences favoring men. There are also sex differences favoring women on episodic-memory tasks requiring both verbal and visuospatial processing and on face-recognition tasks. Thus, there may be a small, general episodic-memory advantage for women—an advantage that can increase by the advantage women have over men in verbal production and can be reversed by the male advantage in visuospatial tasks. In addition, environmental factors affect the magnitude of the sex differences in episodic memory.     

Methylphenidate slows reactions of children with attention deficit disorder during and after an error

A Sternberg memory search task was administered under placebo and methylphenidate to 42 children with cross-situational attention deficit disorder (ADD), 31 children with cross-situational ADD plus oppositional features, and 25 patients with marginal ADD. Overall, stimulant medication enhanced accuracy and speed. In addition, patients reacted faster on correct responses not preceded by an error than on errors (especially false alarms) or on correct responses following an error. The slowness during error reactions may reflect decreased confidence or confusion during stimulus classification. This uncertainty may also lead subjects to respond with greater caution, hence more slowly, on correct responses following errors. Notably, methylphenidate increased the slowing of reactions on error trials as well as on correct reactions following an error. Stimulant medication may augment subjects' persistence when they are uncertain or confused, thereby heightening caution and promoting accuracy on succeeding trials. Consistent with previous reports of the generality of enhancement of performance by stimulant medication, the impact of methylphenidate was comparable for the three subtypes of ADD studied.Jaine Strauss is at Macalester College.This research was supported by National Institute of Mental Health Grants MH32103 and MH38118. We thank Rachel Avery, Christine Carriuolo, Lawrence Ota, the late Helen Pollock, and the University of Rochester's Strong Memorial Hospital Pharmacy for their assistance.     

Face the noise: embodied responses to nonverbal vocalizations of discrete emotions

Extensive prior research has shown that the perception of an emotional facial expression automatically elicits a corresponding facial expression in the observer. Theories of embodied emotion, however, suggest that such reactions might also occur across expressive channels, because simulation is based on integrated motoric and affective representations of that emotion. In the present studies, we examined this idea by focusing on facial and experiential reactions to nonverbal emotion vocalizations. In Studies 1 and 2, we showed that both hearing and reproducing vocalizations of anger, disgust, happiness, and sadness resulted in specific facial behaviors, as well as congruent self-reported emotions (Study 2). In Studies 3 and 4, we showed that the inhibition of congruent facial actions impaired listeners' processing of emotion vocalizations (Study 3), as well as their experiences of a concordant subjective state (Study 4). Results support the idea that cross-channel simulations of others' states serve facilitative functions similar to more strict imitations of observed expressive behavior, suggesting flexibility in the motoric and affective systems involved in emotion processing and interpersonal emotion transfer. We discuss implications for embodiment research and the social consequences of expressing and matching emotions across nonverbal channels.     

How do people with cognitive functional limitations post-stroke manage the use of buses in local public transport?

People with cognitive functional limitations (CFLs) have rarely been the focus of research dealing with road users and their needs. The aim of the present study was to describe how people with CFL post-stroke manage in their use of buses in the framework of their outdoor mobility, and to find out what difficulties, but also what opportunities, they experienced when moving from origin to destination using buses in public transport. Semi-structured interviews combined with participant observations during bus trips with eight persons were performed. Several barriers that have the potential to restrict autonomous outdoor mobility were identified. These barriers were not only represented by well-known infrastructure problems (high pavement curbs, etc.) or ergonomic shortcomings in the buses but, even more so, by specific issues relevant for persons with CFL, e.g. having to cross a road on their way to the bus stop, which poses problems of interaction with fast-moving car traffic. Obtaining all the necessary information prior to and during the trip is difficult and produces insecurity. Often, communication with the bus drivers, not least in connection with the search for information, causes extra stress. Lack of self-confidence and feelings of inferiority add to these problems. Measures to control vehicle speeds, to optimise the communication style of bus drivers with their customers, and to improve customers’ access to information are recommended. Training measures to reassure persons with CFL in connection with their use of the public space are suggested.     

Emotional Mimicry: Why and When We Mimic Emotions

The goal of this review was to provide a brief overview of recent developments in the domain of emotional mimicry research. We argue that emotional signals are intrinsically meaningful within a social relationship, which is crucial for understanding the functionality and boundary conditions of emotional mimicry. On the basis of a review of the literature on facial mimicry of emotion displays, we conclude that the classic matched motor hypothesis does not hold for emotional mimicry. We alternatively propose a contextual view of emotional mimicry, which states that emotional mimicry depends on the social context: we only mimic emotional signals that are interpreted to promote affiliation goals and not necessarily what we see. As a further consequence, we are less likely to mimic strangers and we do not mimic people we do not like nor emotions that signal antagonism.     

Outcome of psychodynamic child psychotherapy in routine practice

The aim of the present naturalistic study was to explore the effectiveness of psychodynamic child psychotherapy in routine practice. The sample comprised 207 psychotherapies with children 4–12?years of age with a broad range of mental health problems. Data on two measures, children’s global assessment scale (CGAS) and strength and difficulties questionnaire (SDQ), were collected pre-post therapy. Within-group changes were analysed using repeated measures mixed-models ANOVA. Individual changes were examined by means of clinical significance. The analyses revealed improvement in general functioning, decrease in problem severity and problem impact on the child’s everyday life, as well as an increase in prosocial behaviour. For CGAS, an interaction effect was discovered suggesting a larger improvement for younger children (4–6?years) than for older children (10–12?years). After therapy, 38% (n 76) achieved clinically significant improvement. Time-limited psychotherapy proved favourable for children assigned to that particular treatment modality. The study generated similar results as previous well-controlled trials, revealing statistically significant results in a large sample and in spite the use of non-specific outcome measures. The study provides everyday evidence to the effectiveness of child psychodynamic treatment with parallel parental work for a broad range of child mental health problems.     

The relativity of time perception produced by facial emotion stimuli

Insults elicit intense emotion. This study tests the hypothesis that one's social image, which is especially salient in honour cultures, influences the way in which one reacts to an insult. Seventy-seven honour-oriented and 72 non-honour oriented participants answered questions about a recent insult episode. Participants experienced both anger and shame in reaction to the insult. However, these emotions resulted in different behaviours. Anger led to verbal attack (i.e., criticising, insulting in return) among all participants. This relationship was explained by participants’ motivation to punish the wrongdoer. Shame, on the other hand, was moderated by honour. Shame led to verbal disapproval of the wrongdoers behaviour, but only among the honour-oriented participants. This relationship was explained by these participants’ motivation to protect their social image. By contrast, shame led to withdrawal among non-honour-oriented participants.     

Who are you looking at? The influence of face gender on visual attention and memory for own- and other-race faces

Previous research suggests that the own-race bias (ORB) in memory for faces is a result of other-race faces receiving less visual attention at encoding. As women typically display an own-gender bias in memory for faces and men do not, we investigated whether face gender and sex of viewer influenced visual attention and memory for own- and other-race faces, and if preferential viewing of own-race faces contributed to the ORB in memory. Participants viewed pairs of female or male own- and other-race faces while their viewing time was recorded. Afterwards, they completed a surprise memory test. We found that (1) other-race males received the initial focus of attention, (2) own-race faces were viewed longer than other-race faces over time, although the difference was larger for female faces, and (3) even though longer viewing time increased the probability of remembering a face, it did not explain the magnified ORB in memory for female faces. Importantly, these findings highlight that face gender moderates attentional responses to and memory for own- and other-race faces.