High impact running improves learning

Regular physical exercise improves cognitive functions and lowers the risk for age-related cognitive decline. Since little is known about the nature and the timing of the underlying mechanisms, we probed whether exercise also has immediate beneficial effects on cognition. Learning performance was assessed directly after high impact anaerobic sprints, low impact aerobic running, or a period of rest in 27 healthy subjects in a randomized cross-over design. Dependent variables comprised learning speed as well as immediate (1 week) and long-term (>8 months) overall success in acquiring a novel vocabulary. Peripheral levels of brain-derived neurotrophic factor (BDNF) and catecholamines (dopamine, epinephrine, norepinephrine) were assessed prior to and after the interventions as well as after learning. We found that vocabulary learning was 20 percent faster after intense physical exercise as compared to the other two conditions. This condition also elicited the strongest increases in BDNF and catecholamine levels. More sustained BDNF levels during learning after intense exercise were related to better short-term learning success, whereas absolute dopamine and epinephrine levels were related to better intermediate (dopamine) and long-term (epinephrine) retentions of the novel vocabulary. Thus, BDNF and two of the catecholamines seem to be mediators by which physical exercise improves learning.     

Assessment protocol for identifying preferred social consequences

Children with autism spectrum disorders (ASD) exhibit deficits in social behavior. Because social consequences may be ineffective or evoke undesirable behavior, teaching interventions for this population may rely heavily on edible or activity reinforcers. This report describes a method, appropriate for young children with ASD, for rapidly identifying social reinforcers and assessing relative preferences among social consequences. The free‐operant behavior of three such children was analyzed in three Social Consequence conditions that alternated with an Extinction condition. The results identified some social consequences that functioned as reinforcers and others to which the child was relatively indifferent. The implications of this study may be particularly pertinent for teaching behavior, like joint attention skills, that is maintained by social reinforcers in the natural environment. Copyright © 2007 John Wiley & Sons, Ltd.     

COMT val158Met and executive control: a test of the benefit of specific deficits to translational research

The role of catechol-O-methyltransferase (COMT) val158met in prefrontal cortical deficits associated with the liability to schizophrenia remains controversial. This study evaluated 464 healthy adult participants using three measures of executive functions in working memory: a 3-back version of the N-back continuous performance task (CPT) and two variants of the AX-CPT. The interpretability of N-back performance was confounded by possible generalized deficits, whereas the AX variants included internal controls for uncovering specific deficits. There was no relationship between the COMT genotype and N-back performance, whereas val/val individuals had a specific deficit on a dot-pattern version of the AX-CPT. In this case, a specific executive function known as context processing appeared to be compromised. These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis.     

"John thinks that Mary feels. . ." False belief in children across affective and physical domains

Children aged 5-8 years (N = 64) were given 3 first- and 3 second-order tasks testing their ability to represent false beliefs about physical facts, positive emotions, and negative emotions. The children were also asked to justify their responses to the test questions. Older children were more successful than younger children at both answering the test questions correctly and justifying their responses. On the first-order problems, performance was better on the physical fact task than on the emotions tasks; the reverse was true for the second-order problems. Children primarily used situational explanations to explain correct judgments on the physical problems, whereas mentalistic explanations were more common than situational explanations on 3 of the 4 emotions tasks. The results extend knowledge of false belief beyond the simple forms studied at the preschool level.     

Suicide intervention trainees' knowledge of myths about suicide

The responses of 70 trainees in suicide intervention to 10 Suicide Opinion Questionnaire items were evaluated for accuracy of their knowledge about suicide myths. Participants were Canadian adults (62 women, 8 men, M (age) = 35 yr.) representing a wide variety of occupations and educational backgrounds. Analysis indicated knowledge for most items was high but less accurate for items concerning the most common method of suicide and suicide risk across the lifespan. Those trained in suicide intervention were more knowledgeable on four items than those awaiting training; they more frequently knew that most suicides are not triggered by an argument with a spouse, people who are depressed are more likely to commit suicide, a person whose parent has committed suicide is at greater risk for suicide, and that shooting is the most common method of suicide in Canada.     

Teachers' knowledge of facts and myths about suicide

Suicidal behavior is a serious public health concern that has prompted the development of prevention strategies, which include increasing community members' knowledge about suicide. Given that teachers are in a key position to recognize and respond to suicidal behavior, this study examined teachers' knowledge about suicide to identify how they need to be educated relative to its prevention. 82 Canadian school teachers from middle and high schools were administered a revised version of the 32-item Facts on Suicide Quiz to examine their knowledge of suicide. Analysis indicated that general information about suicide was limited, while knowledge of clinically relevant information about suicide, e.g., "Suicide rarely happens without warning," was relatively high.     

The relationship between loneliness and interpersonal trust during middle childhood

The authors administered measures of loneliness, generalized trust beliefs in peers, and trust beliefs in specific familiar peers (i.e., opposite-gender peers, same-gender peers, close same-gender peers) to a sample of 63 children (33 girls, 30 boys) from 4th and 5th grades (M age = 10 years, 6 months). They assessed children's trusting behavior by engaging them in a Prisoner's Dilemma game (reciprocal trusting) and by evaluating teachers' ratings. The authors found that, across gender, loneliness was negatively correlated with each measure of trust beliefs and trusting behavior. As expected, the relationship between children's loneliness and trust, specifically trust beliefs in same-gender peers, was stronger for girls than for boys. In support of an additive risk model, the authors found low trust beliefs in same-gender peers and low reciprocal trusting behavior with peers each statistically contributed to loneliness in girls.     

Behavioural treatment of trichotillomania: two-year follow-up results

Post-treatment evaluation studies of behaviour therapy (BT) for trichotillomania (TTM) have shown that BT is successful in reducing symptoms in this impulse-control disorder. The present study was aimed at investigating gain maintenance at long-term follow-up. TTM-related symptoms and other symptom characteristics were evaluated in 28 patients suffering from TTM before and after brief BT and at a 3-month and 2-year follow-up. The manual-based BT consisted of self-control procedures offered in six sessions. Pre-post effect sizes for TTM symptoms at post-treatment evaluation and at the two follow-ups were 2.91, 1.47, and .87. Compared to the post-treatment effects, the 3-month and 2-year follow-up effect sizes had decreased by 49% and 70%, respectively. Better 2-year follow-up results were associated with lower pre-treatment levels of depressive symptoms and with complete abstinence from hair pulling immediately after treatment.