Context specificity of latent inhibition in the snail Cornu aspersum

Animal Cognition - The present study was conducted to assess the context specificity of latent inhibition (LI) in the snail Cornu aspersum, using the appetitive Pavlovian Conditioning procedure of...     

A Methodological Examination of Emotion Inductions in Borderline Personality Disorder: A Comparison of Standardized Versus Idiographic Stimuli

Emotional reactivity is conceptualized as a core feature of borderline personality disorder (BPD) and has been subject to substantial empirical research. The laboratory methods used to elicit emotional reactivity in BPD have varied and findings across studies have been mixed. At present, there is little research evaluating the relative efficacy of different methods in eliciting emotional reactivity in BPD. Thus, the current study examined differences in emotional reactivity among individuals with BPD in response to standardized and idiographic stimuli, and across three specific emotions (sadness, fear, and anger). Individuals with BPD, social anxiety disorder, and healthy controls viewed film clips (i.e., standardized stimuli) or engaged in a personally-relevant imagery task (i.e., idiographic stimuli) while self-reported and physiological indices (skin conductance response and respiratory sinus arrhythmia) of emotion were collected. Results indicated that BPD participants displayed greater reactivity of sadness and anger (but not fear) in response to the idiographic versus standardized stimuli, a pattern that was not exhibited by the other two groups. These findings might explain some of the mixed evidence to date and suggest that idiographic sadness and fear inductions may be more effective for individuals with BPD.     

Common and specific cognitive deficits in schizophrenia: relationships to function

The goals of the present study were to assess the interrelationships among tasks from the MATRICS and CNTRACS batteries, to determine the degree to which tasks from each battery capture unique variance in cognitive dysfunction in schizophrenia, and to determine the ability of tasks from each battery to predict functional outcome. Subjects were 104 schizophrenia patients and 132 healthy control subjects recruited as part of the CNTRACS initiative. All subjects completed four CNTRACS tasks and two tasks from the MATRICS battery: Brief Assessment of Cognition in Schizophrenia Symbol Coding and the Hopkins Verbal Learning Test. Functional outcome was also assessed in the schizophrenia subjects. In both the patient and control groups, we found significant intercorrelations between all higher order cognitive tasks (episodic memory, goal maintenance, processing speed, verbal learning) but minimal relationships with the visual task. For almost all tasks, scores were significantly related to measures of functional outcome, with higher associations between CNTRACS tasks and performance-based measures of function and between one of the MATRICS tasks and self-reported functioning, relative to the other functioning measures. After regressing out variance shared by other tasks, we continued to observe group differences in performance among task residuals, particularly for measures of episodic memory from both batteries, although these residuals did not correlate as robustly with functional outcome as raw test scores. These findings suggest that there exists both shared and specific variance across cognitive tasks related to cognitive and functional impairments in schizophrenia and that measures derived from cognitive neuroscience can predict functional capacity and status in schizophrenia.     

The Parenting and Family Adjustment Scales (PAFAS): an Indonesian Validation Study

Understanding parenting risk and protective factors can help clinicians and researchers to develop effective family interventions. To have knowledge of these risk and protective factors, validated assessment tools are required. Validation studies for parenting measures with Indonesian parents are lacking, despite the need for access to parenting interventions among Indonesian families. This study aimed to validate the Parenting and Family Adjustment Scales (PAFAS), a brief parenting and family adjustment measure developed in Australia that has been validated with Panamanian and Chinese parents. A sample of 210 Indonesian parents with children aged 2–12 years old completed the Indonesian version of the PAFAS and Child Adjustment and Parent Efficacy Scale (CAPES). Confirmatory Factor Analysis (CFA) and Structural Equation Modelling (SEM) were used for analyses. CFA resulted a four-factor PAFAS Parenting scale (15 items) and three-factor PAFAS Family adjustment scale (8 items). SEM analyses with PAFAS and CAPES revealed a good fit of the model of relationships between parent, family and child constructs to the data. The internal consistencies of PAFAS were good or acceptable, with the exception of Parental consistency. Overall, PAFAS had satisfactory psychometric properties. It is a promising measure that can potentially be used to study parenting risk and protective factors among Indonesian families. Item improvement and further validation with more diverse samples are suggested.     

Activating attachment representations impact how we retrieve autobiographical memories

Although much research indicates that proximity to attachment figures confers many psychological benefits, there is little evidence pertaining to how attachment activation may impact autobiographical memory retrieval. Following a negative mood induction to elicit overgeneral autobiographical retrieval, participants (N?=?70) were administered an induction in which they imagined a person who is a strong attachment figure or an acquaintance. Participants then completed an autobiographical memory task to retrieve memories in response to neutral and negative cue words. Attachment priming resulted in less distress, increased retrieval of specific memories, and reduced retrieval of categoric memories. These findings indicate that activation of mental representations of attachment figures can impact on the specificity of autobiographical memory retrieval, and extends prevailing models of autobiographical memory by integrating them with attachment theory.     

Panning for the gold in health research: Incorporating studies’ methodological quality in meta-analysis

Background: Systematic reviews now routinely assess methodological quality to gauge the validity of the included studies and of the synthesis as a whole. Although trends from higher quality studies should be clearer, it is uncertain how often meta-analyses incorporate methodological quality in models of study results either as predictors, or, more interestingly, in interactions with theoretical moderators.

Objective and methods: We survey 200 meta-analyses in three health promotion domains to examine when and how meta-analyses incorporate methodological quality.

Results: Although methodological quality assessments commonly appear in contemporary meta-analyses (usually as scales), they are rarely incorporated in analyses, and still more rarely analysed in interaction with theoretical determinants of the success of health promotions. The few meta-analyses (2.5%) that did include such an interaction analysis showed that moderator results remained significant in higher quality studies or were present only among higher quality studies. We describe how to model quality interactively with theoretically derived moderators and discuss strengths and weaknesses of this approach and in relation to current meta-analytic practice.

Conclusions: In large literatures exhibiting heterogeneous effects, meta-analyses can incorporate methodological quality and generate conclusions that enable greater confidence not only about the substantive phenomenon but also about the role that methodological quality itself plays.     

If We Build It … Will They Come? – Establishing a Cancer Genetics Services Clinic for an Underserved Predominantly Latina Cohort

Background: Cancer genetic counseling and testing is a standard of care option for appropriate families and can identify individuals at increased risk prior to diagnosis, when prevention or detection strategies are most effective. Despite documented efficacy of cancer risk reduction in high-risk individuals, underserved and minority individuals have a disproportionate cancer burden and limited access to genetic counseling. Methods: A needs assessment survey documented gaps in knowledge and interest in prevention. Satellite clinics were established at two indigent healthcare systems. Cancer genetics CME lectures were conducted and referral guidelines disseminated to clinicians who referred patients for counseling. Results: An increase in clinician knowledge was demonstrated post-CME and reflected by quality referrals. Eighty-eight percent of patients kept their appointments. In the predominantly Latina⁶ (n=77) clinic population, 71.4% were affected with cancer, and 17 mutation positive families were identified. Preliminary data shows a positive impact on patients' motivation and behavior. The majority has expressed satisfaction and reduction in anxiety. Conclusions: This study demonstrates feasibility and acceptability of cancer genetics services in this population, suggesting the potential to reduce cancer morbidity in underserved, high-risk families.“Latino” is the most common census term for individuals of Spanish, Mexican, Central and South American, Cuban, or Puerto Rican descent, referring to ethnicity, and is generally considered a more ethnically/culturally based term for individuals of the aforementioned groups. As this cohort is female the feminine noun “Latina” is used     

The automatic orienting of attention to goal-relevant stimuli

It is often assumed that attention is automatically allocated to stimuli relevant to one’s actual goals. However, the existing evidence for this idea is limited in several ways. We investigated whether words relevant to a person’s current goal influence the orienting of attention even when an intention to attend to the goal-relevant stimuli is not present. In two experiments, participants performed a modified spatial cueing paradigm combined with a second task that induced a goal. The results of the experiments showed that the induced goal led to the orientation of attention to goal-relevant words in the spatial cueing task. This effect was not found for words semantically related to the goal-relevant words. The results provide evidence for motivational accounts of attention, which state that the automatic allocation of attention is guided by the current goals of a person.