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211.
212.
Matthias Adam 《国际科学哲学研究》2004,18(2-3):117-132
It is a widely shared view among philosophers of science that the theory‐dependence (or theory‐ladenness) of observations is worrying, because it can bias empirical tests in favour of the tested theories. These doubts are taken to be dispelled if an observation is influenced by a theory independent of the tested theory and thus circularity is avoided, while (partially) circular tests are taken to require special attention. Contrary to this consensus, it is argued that the epistemic value of theory‐dependent tests has nothing to do with the circularity or non‐circularity of the test, but is instead based on the minimal empiricality and reliability of observations. Since theory‐dependence does not in general prevent observations fulfilling these requirements, it should not be regarded as a phenomenon that is basically detrimental, but as neutral with respect to successful scientific knowledge gathering. 相似文献
213.
Croom AM 《Integrative psychological & behavioral science》2012,46(1):90-117
Aesthetic non-cognitivists deny that aesthetic statements express genuinely aesthetic beliefs and instead hold that they work
primarily to express something non-cognitive, such as attitudes of approval or disapproval, or desire. Non-cognitivists deny
that aesthetic statements express aesthetic beliefs because they deny that there are aesthetic features in the world for aesthetic
beliefs to represent. Their assumption, shared by scientists and theorists of mind alike, was that language-users possess
cognitive mechanisms with which to objectively grasp abstract rules fixed independently of human responses, and that cognizers
are thereby capable of grasping rules for the correct application of aesthetic concepts without relying on evaluation or enculturation.
However, in this article I use Wittgenstein’s rule-following considerations to argue that psychological theories grounded
upon this so-called objective model of rule-following fail to adequately account for concept acquisition and mastery. I argue
that this is because linguistic enculturation, and the perceptual learning that’s often involved, influences and enables the
mastery of aesthetic concepts. I argue that part of what’s involved in speaking aesthetically is to belong to a cultural practice of making sense of things aesthetically, and that it’s within a socio-linguistic community, and that community’s practices, that such aesthetic
sense can be made intelligible. 相似文献
214.
J. Farley Norman Jessica S. Holmin Amanda M. Beers Jacob R. Cheeseman Cecilia Ronning Angela G. Stethen Adam L. Frost 《Attention, perception & psychophysics》2012,74(7):1512-1521
Two experiments evaluated the ability of younger and older adults to visually discriminate 3-D shape as a function of surface coherence. The coherence was manipulated by embedding the 3-D surfaces in volumetric noise (e.g., for a 55?% coherent surface, 55?% of the stimulus points fell on a 3-D surface, while 45?% of the points occupied random locations within the same volume of space). The 3-D surfaces were defined by static binocular disparity, dynamic binocular disparity, and motion. The results of both experiments demonstrated significant effects of age: Older adults required more coherence (tolerated volumetric noise less) for reliable shape discrimination than did younger adults. Motion-defined and static-binocular-disparity-defined surfaces resulted in similar coherence thresholds. However, performance for dynamic-binocular-disparity-defined surfaces was superior (i.e., the observers?? surface coherence thresholds were lowest for these stimuli). The results of both experiments showed that younger and older adults possess considerable tolerance to the disrupting effects of volumetric noise; the observers could reliably discriminate 3-D surface shape even when 45?% of the stimulus points (or more) constituted noise. 相似文献
215.
Adam Pryor 《Zygon》2011,46(4):835-856
Abstract Emergence theory has generated many significant new questions for dialogue between theology and science. My work will examine the models of one emergence theorist, Terrence Deacon, and consider the constructive potential of Tillich's multidimensional unity of life for responding to the theological ramifications of this account of emergence theory. Such a Tillich‐inspired constructive process will rely upon Robert Russell's method of “Creative Mutual Interaction.” Building on the interactive quality of Russell's method, I will also begin to offer suggestions for how Tillich's theological themes might influence scientific research programs using Deacon's emergence theory by contributing to the process of defining life. Finally, I will conclude by identifying three facets of continued research that stem from this analysis, focusing primarily on its implications for theological anthropology and what it means to be in the image of God. 相似文献
216.
Rats administered the cannabinoid agonist WIN55,212-2 or the antagonist SR141716A exhibit marked deficits during acquisition of delay eyeblink conditioning, as noted by Steinmetz and Freeman in an earlier study. However, the effects of these drugs on retention and extinction of eyeblink conditioning have not been assessed. The present study examined the effects of WIN55,212-2 and SR141716A on retention and extinction of delay eyeblink conditioning in rats. Rats were given acquisition training for five daily sessions followed by one session of retention training with subcutaneous administration of 3 mg/kg of WIN55,212-2 or 5 mg/kg of SR141716A and an additional session with the vehicle. Two sessions of extinction training were then given with WIN55,212-2, SR141716A, or vehicle. Retention and extinction were impaired by WIN55,212-2, whereas SR141716A produced no deficits. The extinction deficit in rats given WIN55,212-2 was observed only during the first session, suggesting a specific impairment in short-term plasticity mechanisms. The current results and previous findings indicate that the cannabinoid system modulates cerebellar contributions to acquisition, retention, and extinction of eyeblink conditioning. 相似文献
217.
Pavlovian eyeblink conditioning has been used extensively as a model system for examining the neural mechanisms underlying associative learning. Delay eyeblink conditioning depends on the intermediate cerebellum ipsilateral to the conditioned eye. Evidence favors a two-site plasticity model within the cerebellum with long-term depression of parallel fiber synapses on Purkinje cells and long-term potentiation of mossy fiber synapses on neurons in the anterior interpositus nucleus. Conditioned stimulus and unconditioned stimulus inputs arise from the pontine nuclei and inferior olive, respectively, converging in the cerebellar cortex and deep nuclei. Projections from subcortical sensory nuclei to the pontine nuclei that are necessary for eyeblink conditioning are beginning to be identified, and recent studies indicate that there are dynamic interactions between sensory thalamic nuclei and the cerebellum during eyeblink conditioning. Cerebellar output is projected to the magnocellular red nucleus and then to the motor nuclei that generate the blink response(s). Tremendous progress has been made toward determining the neural mechanisms of delay eyeblink conditioning but there are still significant gaps in our understanding of the necessary neural circuitry and plasticity mechanisms underlying cerebellar learning. 相似文献
218.
Kimbrough A Kwon B Eckel LA Houpt TA 《Learning & memory (Cold Spring Harbor, N.Y.)》2011,18(5):292-295
5-bromo-2-deoxyuridine (BrdU) is often used in studies of adult neurogenesis and olfactory learning, but it can also have toxic effects on highly proliferative tissue. We found that pairing Kool-Aid flavors with acute systemic injections of BrdU induced strong conditioned flavor aversions. Intermittent injections during Kool-Aid-glucose conditioning interfered with learning of a conditioned flavor-nutrient preference. Acute injection of BrdU also elevated plasma corticosterone levels and induced c-Fos in the visceral neuraxis. Thus, acute or intermittent systemic injections of BrdU (50-200 mg/kg) have aversive effects that may interfere with learning. 相似文献
219.
Matzel LD Light KR Wass C Colas-Zelin D Denman-Brice A Waddel AC Kolata S 《Learning & memory (Cold Spring Harbor, N.Y.)》2011,18(5):345-356
Learning, attentional, and perseverative deficits are characteristic of cognitive aging. In this study, genetically diverse CD-1 mice underwent longitudinal training in a task asserted to tax working memory capacity and its dependence on selective attention. Beginning at 3 mo of age, animals were trained for 12 d to perform in a dual radial-arm maze task that required the mice to remember and operate on two sets of overlapping guidance (spatial) cues. As previously reported, this training resulted in an immediate (at 4 mo of age) improvement in the animals' aggregate performance across a battery of five learning tasks. Subsequently, these animals received an additional 3 d of working memory training at 3-wk intervals for 15 mo (totaling 66 training sessions), and at 18 mo of age were assessed on a selective attention task, a second set of learning tasks, and variations of those tasks that required the animals to modify the previously learned response. Both attentional and learning abilities (on passive avoidance, active avoidance, and reinforced alternation tasks) were impaired in aged animals that had not received working memory training. Likewise, these aged animals exhibited consistent deficits when required to modify a previously instantiated learned response (in reinforced alternation, active avoidance, and spatial water maze). In contrast, these attentional, learning, and perseverative deficits were attenuated in aged animals that had undergone lifelong working memory exercise. These results suggest that general impairments of learning, attention, and cognitive flexibility may be mitigated by a cognitive exercise regimen that requires chronic attentional engagement. 相似文献
220.
Both humans and non-human animals have the ability to navigate and make decisions within complex environments. This ability is largely dependent upon learning and memory processes, many of which are known to depend on NMDA-sensitive receptors. When humans come to difficult decisions they often pause to deliberate over their choices. Similarly, rats pause at difficult choice points. This behavior, known as vicarious trial and error (VTE), is hippocampally dependent and entails neurophysiological representations of expectations of future outcomes in hippocampus and downstream structures. In order to determine the dependence of VTE behaviors on NMDA-sensitive receptors, we tested rats on a Multiple-T choice task with a reward-delivery reversal known to elicit VTE. Rats under the influence of NMDA-receptor antagonists (CPP) showed a significant reduction in VTE, particularly at the reward reversal, implying a role for NMDA-sensitive receptors in the generation of vicarious trial and error behaviors. 相似文献