Alcohol, subliminal stimulation, and disinhibitory processes

An experiment was performed to test the hypothesis that an unconscious conflict between a wish to attain symbiotic oneness with another person on the one hand and personal independence on the other, should be weakened by alcohol if the main effect of intoxication is to reduce the strength of psychological inhibitions. In turn, a reduction in such conflicts should improve motor performance. Data indicated no such effects, and it was concluded that the disinhibition hypothesis as an explanation of alcohol-related behavior was not supported.     

Effects of alcohol on cognitive performance measured with Stroop's Color Word Test

An experiment was performed to test whether alcohol intoxication leads to cognitive disinhibition as measured by the Color Word Test. In psychoanalytic terms, it was hypothesized that alcohol would decrease secondary process functioning leading to disinhibition and so make it easier to perform a primary process function. 24 men and 24 women participated and were randomly assigned to an Alcohol group, a Placebo group or a Control group. The alcohol dose was 1.0 ml of 100% alcohol/kg body weight. No statistically significant differences were found on any of the three dependent measures, number of errors, number of hesitations and total time needed, except that men in the Alcohol group needed significantly longer time to complete the test. These results indicate that cognitive disinhibition is not valid as an explanation for alcohol-related changes in cognitive functioning.     

Effects of alcohol on prolonged cognitive performance measured with Stroop's Color Word Test

24 men and 24 women were randomly assigned in equal numbers to an Alcohol group, a Placebo group, or a Control group. The alcohol dose was 1.0 ml of 100% alcohol/kg of body weight. Subjects were tested three consecutive times using Stroop's Color Word Test. The dependent measures were total time needed to complete the test, number of errors made and number of hesitations. Data were grouped into three blocks of 100 words. Results indicated that number of hesitations was too insensitive a measure to yield any significant effects. On the two first measures alcohol had a detrimental effect in that the Alcohol group needed more time to complete the test and made more errors than the Placebo group. There was also a significant interaction of alcohol dose by sex by blocks on both these measures, indicating that the detrimental effect of alcohol over time was restricted to women. Different implications of the results were discussed.     

Task clarification, performance feedback, and social praise: Procedures for improving the customer service of bank tellers

Customer service for bank tellers was defined in terms of 11 verbal behavior categories. An audio-recording system was used to track the occurrence of behaviors in these categories for six retail banking tellers. Three behavior management interventions (task clarification, performance feedback, and social praise), applied in sequence, were designed to improve overall teller performance with regard to the behavioral categories targeted. Clarification was accomplished by providing clear delineation of the various target categories, with specific examples of the behaviors in each. Feedback entailed presentation of ongoing verbal and visual information regarding teller performance. Praise consisted of verbal recognition of teller performance by branch managers. Results showed that clarification effects emerged quickly, producing an overall increase in desired behaviors of 12% over baseline. Feedback and praise effects occurred more gradually, resulting in overall increases of 6% and 7%, respectively. A suspension of all procedures led to a decline in overall performance, whereas reinstatement of feedback and praise was again accompanied by performance improvement. These findings extend the generality of behavior management applications and help to distinguish between possible antecedent and consequent effects of performance feedback.     

Acute meningitis with cerebrospinal fluid eosinophilia: neurocysticercosis

Neurocysticercosis is a very rare disease in Central Europe. This is a report about an 18 year old patient with acute meningitis and eosinophilia in cerebrospinal fluid. The findings and outcome of a short treatment with Praziquantel are discussed.     

Attrition and the Student Who is Certain

A study of 89 male students at a small liberal arts college tested the hypothesis that a student whose statement about vocational and/or academic goals expressed certainty and whose grade-point average was below a 2.00 at the end of one year would probably not graduate. The hypothesis had both statistical and practical significance since loss from this group was 75 per cent compared to an average loss of 37.1 per cent (Test of Proportions, z = 2.766, P = .0028).     

What is the Role of the Arts in Medical Education and Patient Care? A Survey-based Qualitative Study

To inform medical education reform efforts, we systematically collected information on the level of arts and humanities engagement in our medical school community. Attitudes regarding incorporating arts and humanities-based teaching methods into medical education and patient care were also assessed. An IRB-approved survey was electronically distributed to all faculty, residents, fellows, and students at our medical school. Questions focused on personal practice of the arts and/or humanities, as well as perceptions of, and experience with formally incorporating these into medical teaching. Of 13,512 community members surveyed, 2,775 responded (21% overall response rate). A majority of respondents agreed or strongly agreed that medical education and patient care could be "enhanced" by the integration of the arts (67% and 74% respectively). There was enthusiastic support for the creation of a formal program in the arts at our medical school (72 %). Integration of the arts into medical education may have a role in improving the quality of medical training and would likely be well received by teachers and learners.     

Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice

Many studies have used "reverse" genetics to produce "knock-out" and transgenic mice to explore the roles of various molecules in long-term potentiation (LTP) and spatial memory. The existence of a variety of inbred strains of mice provides an additional way of exploring the genetic bases of learning and memory. We examined behavioral memory and LTP expression in area CA1 of hippocampal slices prepared from four different inbred strains of mice: C57BL/6J, CBA/J, DBA/2J, and 129/SvEms-+(Ter?)/J. We found that LTP induced by four 100-Hz trains of stimulation was robust and long-lasting in C57BL/6J and DBA/2J mice but decayed in CBA/J and 129/SvEms-+(Ter?)/J mice. LTP induced by one 100-Hz train was significantly smaller after 1 hr in the 129/SvEms-+(Ter?)/J mice than in the other three strains. Theta-burst LTP was shorter lasting in CBA/J, DBA/2J, and 129/SvEms-+(Ter?)/J mice than in C57BL/6J mice. We also observed specific memory deficits, among particular mouse strains, in spatial and nonspatial tests of hippocampus-dependent memory. CBA/J mice showed defective learning in the Morris water maze, and both DBA/2J and CBA/J strains displayed deficient long-term memory in contextual and cued fear conditioning tests. Our findings provide strong support for a genetic basis for some forms of synaptic plasticity that are linked to behavioral long-term memory and suggest that genetic background can influence the electrophysiological and behavioral phenotypes observed in genetically modified mice generated for elucidating the molecular bases of learning, memory, and LTP.