Enhanced retention in the passive-avoidance task by 5-HT(1A) receptor blockade is not associated with increased activity of the central nucleus of the amygdala

The effect of blockade of 5-HT1A receptors was investigated on (1). retention in a mildly aversive passive-avoidance task, and (2). spontaneous single-unit activity of central nucleus of the amygdala (CeA) neurons, a brain site implicated in modulation of retention. Systemic administration of the selective 5-HT1A antagonist NAN-190 immediately after training markedly-and dose-dependently-facilitated retention in the passive-avoidance task; enhanced retention was time-dependent and was not attributable to variations in wattages of shock received by animals. Systemic administration of NAN-190 had mixed effects on spontaneous single-unit activity of CeA neurons recorded extracellularly in vivo; microiontophoretic application of 5-HT, in contrast, consistently and potently suppressed CeA activity. The present findings-that 5-HT1A receptor blockade by NAN-190 (1). enhances retention in the passive-avoidance task, and (2). does not consistently increase spontaneous neuronal activity of the CeA-provide evidence that a serotonergic system tonically inhibits modulation of retention in the passive-avoidance task through activation of the 5-HT1A receptor subtype at brain sites located outside the CeA.     

A cognitive-perceptual analysis of projective tests used with children.

There are both general and specific problems with projective tests--the production, comprehension, and interpretation of two-dimensional visual representations. At the general level, there is a need to integrate findings from the neuro- and cognitive sciences, cognitive, perceptual, and affective development, and the understanding and interpretation of pictorial material based on the accumulated research base in the arts. At the specific level, much of the research base on projective tests is poor or outdated; evidence for clinical utility is mixed or negative; and the tests possess poor reliability and validity while the putative underlying psychological process of projection" has not been subject to rigorous empirical examination--the term remains vague and elusive. While earlier critiques and reviews have focused on problems in validity and reliability, their has been a lack of attention to the development of children's pictorial abilities as pertain to projective techniques. Although many of the principles delineated here also apply to adolescents and adults, an important challenge for clinicians is to develop and employ better methods in the "projective" assessment of children.     

An interpersonal analysis of pathological personality traits in DSM-5

The proposed changes to the personality disorder section of the Diagnostic and statistical manual of mental disorders (5th ed.) places an increased focus on interpersonal impairment as one of the defining features of personality psychopathology. In addition, a proposed trait model has been offered to provide a means of capturing phenotypic variation on the expression of personality disorder. In this study, the authors subject the proposed DSM-5 traits to interpersonal analysis using the inventory of interpersonal problems-circumplex scales via the structural summary method for circumplex data. DSM-5 traits were consistently associated with generalized interpersonal dysfunction suggesting that they are maladaptive in nature, the majority of traits demonstrated discriminant validity with prototypical and differentiated interpersonal problem profiles, and conformed well to a priori hypothesized associations. These results are discussed in the context of the DSM-5 proposal and contemporary interpersonal theory, with a particular focus on potential areas for expansion of the DSM-5 trait model.     

Rats distinguish between absence of events and lack of evidence in contingency learning

The goal of three experiments was to study whether rats are aware of the difference between absence of events and lack of evidence. We used a Pavlovian extinction paradigm in which lights consistently signaling sucrose were suddenly paired with the absence of sucrose. The crucial manipulation involved the absent outcomes in the extinction phase. Whereas in the Cover conditions, access to the drinking receptacle was blocked by a metal plate, in the No Cover conditions, the drinking receptacle was accessible. The Test phase showed that in the Cover conditions, the measured expectancies of sucrose were clearly at a higher level than in the No Cover conditions. We compare two competing theories potentially explaining the findings. A cognitive theory interprets the observed effect as evidence that the rats were able to understand that the cover blocked informational access to the outcome information, and therefore the changed learning input did not necessarily signify a change of the underlying contingency in the world. An alternative associationist account, renewal theory, might instead explain the relative sparing of extinction in the Cover condition as a consequence of context change. We discuss the merits of both theories as accounts of our data and conclude that the cognitive explanation is in this case preferred.     

An empirical examination of distributional assumptions underlying the relationship between personality disorder symptoms and personality traits

This article examines the relationship between personality disorder (PD) symptoms and personality traits using a variety of distributional assumptions. Prior work in this area relies almost exclusively on linear models that treat PD symptoms as normally distributed and continuous. However, these assumptions rarely hold, and thus the results of prior studies are potentially biased. Here we explore the effect of varying the distributions underlying regression models relating PD symptomatology to personality traits using the initial wave of the Longitudinal Study of Personality Disorders (N = 250; Lenzenweger, 1999), a university-based sample selected to include PD rates resembling epidemiological samples. PD symptoms were regressed on personality traits. The distributions underlying the dependent variable (i.e., PD symptoms) were variously modeled as normally distributed, as counts (Poisson, Negative-Binomial), and with two-part mixture distributions (zero-inflated, hurdle). We found that treating symptoms as normally distributed resulted in violations of model assumptions, that the negative-binomial and hurdle models were empirically equivalent, but that the coefficients achieving significance often differ depending on which part of the mixture distributions are being predicted (i.e., presence vs. severity of PD). Results have implications for how the relationship between normal and abnormal personality is understood. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Measurement Equivalence Across Racial/Ethnic Groups of the Mood and Feelings Questionnaire for Childhood Depression

As research continues to document differences in the prevalence of mental health problems such as depression across racial/ethnic groups, the issue of measurement equivalence becomes increasingly important to address. The Mood and Feelings Questionnaire (MFQ) is a widely used screening tool for child and adolescent depression. This study applied a differential item functioning (DIF) framework to data from a sample of 6th and 8th grade students in the Seattle Public School District (N = 3,593) to investigate the measurement equivalence of the MFQ. Several items in the MFQ were found to have DIF, but this DIF was associated with negligible individual- or group-level impact. These results suggest that differences in MFQ scores across groups are unlikely to be caused by measurement non-equivalence.     

Aggression Among Children with ADHD,Anxiety, or Co-occurring Symptoms: Competing Exacerbation and Attenuation Hypotheses

Competing hypotheses for explaining the role of anxiety in the relation between attention-deficit/hyperactivity disorder (ADHD) symptoms and childhood aggression were evaluated. Two studies tested whether anxiety exacerbated, attenuated, or had no effect on the relation between ADHD and aggression subtypes among psychiatrically hospitalized children. In Study 1 (N = 99), children who scored above clinical cut-off levels for anxiety only, ADHD only, and co-occurring ADHD and anxiety were compared on aggression subtypes (i.e., reactive, proactive, overt, and relational aggression). In Study 2, the moderating role of anxiety on the relation between ADHD and aggression subtypes was examined with a larger sample (N = 265) and with continuous variables. No support was found for either the attenuation or exacerbation hypothesis, and results remained consistent when separately examining hyperactivity/impulsivity and inattention symptoms of ADHD. Although ADHD symptoms were significantly associated with all aggression subtypes, this association did not remain when including symptoms of oppositional defiant disorder.     

Adaptive and qualitative changes in encoding strategy with experience: evidence from the test-expectancy paradigm

Three experiments demonstrated learners' abilities to adaptively and qualitatively accommodate their encoding strategies to the demands of an upcoming test. Stimuli were word pairs. In Experiment 1, test expectancy was induced for either cued recall (of targets given cues) or free recall (of targets only) across 4 study-test cycles of the same test format, followed by a final critical cycle featuring either the expected or the unexpected test format. For final tests of both cued and free recall, participants who had expected that test format outperformed those who had not. This disordinal interaction, supported by recognition and self-report data, demonstrated not mere differences in effort based on anticipated test difficulty, but rather qualitative and appropriate differences in encoding strategies based on expected task demands. Participants also came to appropriately modulate metacognitive monitoring (Experiment 2) and study-time allocation (Experiment 3) across study-test cycles. Item and associative recognition performance, as well as self-report data, revealed shifts in encoding strategies across trials; these results were used to characterize and evaluate the different strategies that participants employed for cued versus free recall and to assess the optimality of participants' metacognitive control of encoding strategies. Taken together, these data illustrate a sophisticated form of metacognitive control, in which learners qualitatively shift encoding strategies to match the demands of anticipated tests.     

Hoping for more: The influence of outcome desirability on information seeking and predictions about relative quantities

People must often engage in sequential sampling in order to make predictions about the relative quantities of two options. We investigated how directional motives influence sampling selections and resulting predictions in such cases. We used a paradigm in which participants had limited time to sample items and make predictions about which side of the screen contained more of a critical item. Sampling selections were biased by monetary desirability manipulations, and participants exhibited a desirability bias for both dichotomous and continuous predictions.