Genomic Counseling in the Newborn Period: Experiences and Views of Genetic Counselors

As newborn screening (NBS) technology expands, genetic counselors will become more involved in counseling for NBS results, including those potentially generated from whole exome sequencing (WES) and eventually whole genome sequencing (WGS). Members of the National Society of Genetic Counselors (NSGC) responded to an online survey (n?=?208) regarding genomic counseling in the context of NBS. The majority of participants (82.1 %) did not feel prepared to counsel for WGS results from NBS. Counselors with previous WES/WGS counseling experience felt more prepared (p?=?0.005) to counsel for WGS results from NBS than those without WES/WGS experience. Overall, counselors expressed ethical and practical concerns regarding WGS in NBS, as well as a need for additional training regarding this application of the technology before it is implemented. Based on the results of this study, genetic counselors voice caution to the larger genetics community regarding expansion of NBS to incorporate genomic sequencing and advocate for additional education prior to initiating WGS into NBS.     

Time,space, and memory for order

Information about the order of items in a sequence can be conveyed either spatially or temporally. In the present investigation, we examined whether these different modes of presentation map onto compatible mental representations of serial order. We examined this issue in three immediate serial-recall experiments, in which participants recalled lists of letters in the temporal order in which they had appeared. Each letter in a to-be-remembered sequence was presented in a unique spatial position, with the order of these spatial positions progressing from either left to right or right to left. In this way, the visually presented lists contained both temporal and spatial order information. Recall of the temporal order information was more accurate with congruent spatial order information—that is, when the letters progressed from left to right, following the typical reading direction of English—than when the spatial order information was incongruent. These results suggest compatible representations of serial order when sequences are conveyed spatially and temporally.     

Mind-Wandering and Childhood ADHD: Experimental Manipulations across Laboratory and Naturalistic Settings

Research on Child and Adolescent Psychopathology - The conceptual overlap between mind-wandering and attention-deficit/hyperactivity disorder (ADHD)-related impairments is considerable, yet little...     

Religiosity and Exposure to Users in Explaining Illicit Drug Use among Emerging Adults

Religiosity is a protective factor against illicit drug use, but further investigation is needed to delineate which components of religiosity are protective against use. A racially diverse sample (N = 962) was surveyed about religiosity, exposure to users, and recent use of marijuana, powder cocaine, ecstasy, and nonmedical use of opioids and amphetamine. Results suggest that identifying as Agnostic increased odds of use for each of the five drugs; however, this effect disappeared when controlling for religious importance and attendance. High levels of religious attendance were protective against recent use of marijuana and cocaine, but protective effects diminished when controlling for exposure to users, which was a robust predictor of use of every drug. Religion is a protective mechanism against drug use, but this effect may diminish in light of exposure to users. Alternative preventative methods need to be directed toward individuals who are not religious or are highly exposed to users.     

Surviving a Lawsuit Against a Counseling Program: Lessons Learned From Ward v. Wilbanks

This article features information about a lawsuit brought by a former student against Eastern Michigan University and its counseling program. In addition to describing the major elements of the lawsuit, the authors reflect on lessons learned and offer recommendations for other counseling programs.     

Beyond slots and resources: Grounding cognitive concepts in neural dynamics

Research over the past decade has suggested that the ability to hold information in visual working memory (VWM) may be limited to as few as three to four items. However, the precise nature and source of these capacity limits remains hotly debated. Most commonly, capacity limits have been inferred from studies of visual change detection, in which performance declines systematically as a function of the number of items that participants must remember. According to one view, such declines indicate that a limited number of fixed-resolution representations are held in independent memory “slots.” Another view suggests that such capacity limits are more apparent than real, but emerge as limited memory resources are distributed across more to-be-remembered items. Here we argue that, although both perspectives have merit and have generated and explained impressive amounts of empirical data, their central focus on the representations—rather than processes—underlying VWM may ultimately limit continuing progress in this area. As an alternative, we describe a neurally grounded, process-based approach to VWM: the dynamic field theory. Simulations demonstrate that this model can account for key aspects of behavioral performance in change detection, in addition to generating novel behavioral predictions that have been confirmed experimentally. Furthermore, we describe extensions of the model to recall tasks, the integration of visual features, cognitive development, individual differences, and functional imaging studies of VWM. We conclude by discussing the importance of grounding psychological concepts in neural dynamics, as a first step toward understanding the link between brain and behavior.     

Effectiveness of testosterone therapy for masculinizing voice in transgender patients: A meta-analytic review

Background: Testosterone therapy is the predominant treatment for voice masculinization in transgender patients. Although lowering of voice fundamental frequency (f₀) occurs with testosterone therapy, evidence suggests voice and gender identity may not fully align—i.e., voice-gender congruence may not be achieved—with its use.

Aim: This meta-analytic review evaluates the effectiveness of testosterone therapy to masculinize voice in transgender patients.

Methods: Multiple electronic databases were queried (inclusion dates: from database inception up to October 27, 2017) to identify original research on voice masculinization using testosterone therapy. Nineteen articles were included in this meta-analytic review, which followed PRISMA guidelines. In addition to qualitative analyses, random effects proportion meta-analyses were performed on data related to f₀, voice-gender congruence, voice problems, and satisfaction with voice.

Results: A meta-analysis on f₀ data showed after 1 year of testosterone therapy a combined estimate of 21% of participants (95% confidence interval [CI]: 5%–43%; I²: 59.9%) did not achieve cisgender male normative frequencies (f₀ ≤ 131 Hz). Meta-analyses on incomplete voice-gender congruence and voice problems indicated combined estimates of 21% (95% CI: 10%–34%; I²: 0.0%) and 46% (95% CI: 14%–79%; I²: 90.2%), respectively. Regarding incomplete satisfaction with voice, a meta-analysis showed a combined estimate of 16% (95% CI: 7%–28%; I²: 0.0%).

Discussion: We found that not all transgender patients using testosterone therapy to masculinize voice should expect f₀ lowering to cisgender male normative frequencies after 1 year. The vocal transition may involve voice problems for many patients, and some might not achieve voice-gender congruence without additional, voice-specific intervention. Given these findings, a voice evaluation should occur prior to initiating testosterone therapy and involve counseling on expectations for voice. Transgender patients who pursue voice masculinization may need management from laryngology and speech and language therapy to improve voice-gender congruence, mitigate voice problems, and increase satisfaction with voice.     

A Descriptive Examination of Prisonization through the Lens of Post-Exoneration Offending

Prisonization, which seeks to explain criminal behavior as a function of past prison experiences, has been examined through many lenses; however, more novel approaches to exploring prisonization have been lacking. This study uniquely explores the concept of prisonization by describing the post-release behavior of 118 wrongfully convicted individuals, known as exonerees.

Conclusions were drawn from a dataset of exonerees and criminal history background searches. Comparative analyses show that exonerees without priors serve longer sentences and demonstrate a shorter time to failure (as measured by post-release offending). Offending among this cohort may suggest that otherwise law-abiding citizens were negatively affected by their experience in prison and, furthermore, may indirectly support the notion that being imprisoned fosters criminality in individuals. These results can support conceptual and practical advancements.     

UNDERSTANDING PARENTING STRESS AND CHILDREN'S BEHAVIOR PROBLEMS AMONG HOMELESS,SUBSTANCE‐ABUSING MOTHERS

This article tested a model of parenting stress as a mediator between maternal depressive symptoms, emotion regulation, and child behavior problems using a sample of homeless, substance‐abusing mothers. Participants were 119 homeless mothers (ages 18–24 years) and their young children (ages 0–6 years). Mothers responded to questions about their depressive symptoms, emotion regulation, parenting stress, and child behavior problems. A path analysis showed that maternal depressive symptoms were positively associated with child behavior problems through increased parenting stress whereas maternal cognitive reappraisal was negatively associated with child behavior problems through decreased parenting stress. Moreover, maternal expressive suppression was negatively related to child externalizing problems. Findings support the parenting stress theory and highlight maternal parenting stress as a mechanism associated with homeless children's mental health risk. This study has significant implications for understanding the parenting processes underlying child's resilience in the context of homelessness and maternal substance use.