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21.
In endless facets of physiology, there are points of homeostatic balance, such that too much or too litttle of something can both be deleterious (i.e., an "inverse U" pattern). This is particularly true when considering glucocorticoids (GCs), the adrenals steroid secreted during stress. In the first part of this paper, I review a number of realms in which a paucity and an excess of GCs are both damaging. Some findings are classical (for example, concerning GC effects upon body weight), while some are quite recent and have considerable implications for both physiology and pathophysiology (for example, inverse U's of GC actions in the realm of immunity and neuronal survival). The second part of the review considers the far thornier issue of how such inverse U's of GC actions are generated on a cellular and molecular level. One solution that has evolved, primarily in the hippocampus within the nervous system, involves the presence of two different types of receptors for GCs within the same cells; so long as the two receptors have very different affinities and mediate opposing effects on some cellular endpoint, an inverse U will emerge. The second solution, found in a number of peripheral tissues, involves GCs having opposing effects on the amount of some signal being generated (e.g., an immune cytokine) and the sensitivity of target tissues to that signal; under conditions that appear to be physiologically relevant, inverse U's emerge from this pattern as well. The final section of this review considers the enormous role played by Bruce McEwen in the emergence of this literature. I suggest that while much of this obviously has to do with the facts that have come from his group, another substantial contribution is from his steadying and supportive personality, the veritable embodiment of homeostatic balance.  相似文献   
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This article describes a national survey regarding services for continuing education units (CEUs) in state branches of AACD.  相似文献   
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The authors describe a five-step model of conflict reduction suitable for use by practicing counselors. They present the model in how-to-do-it fashion, supplementing it with illustrations. They describe the reactions of eight counselors who used the model in 37 conflict cases and present the responses of the persons involved in the conflicts.  相似文献   
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This paper elucidates the special stresses and supports experienced by military families and their relation to individual decompensation, which is viewed as an expression of family disequilibrium and is often best treated in the family. Periodic separations, frequent moves, and rigid hierarchy present difficult problems that tax the resourcefulness of the military and its families. Healthy and maladaptive patterns are discussed.  相似文献   
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The skills of the counselor are too important to be used only in the guidance office. The counselor should move into the school and the community to teach others the various skills of counseling and interpersonal communication. Microcounseling is a systematic method for teaching counseling skills in a short period of time. The author explains the relationship of microcounseling and counselor education to the role of the practicing counselor. He believes that conducting systematic training programs in such skills as microcounseling should become an important role for counselors.  相似文献   
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This study investigated the relationship between interaction behavior in a small group setting and the resulting perceptions group members have of one another. Trained raters coded the interaction behavior of subjects, who discussed a task-oriented topic in small groups. Results indicate that interaction behavior can account for a substantial percentage of the variance in group members’ perceptions of one another. Apparently, the same interaction behavior may simultaneously result in both more positive and more negative perceptions on the part of other group members, suggesting that different interaction strategies are appropriate for varying desired personal outcomes.  相似文献   
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