Heart-rate responses of infant rats and guinea pigs to stimulus onset and offset: tests of the generality of a bidirectional effect

To test the generality, across modality and across species, of a bidirectional effect of photic stimulation in infant rats found in previous experiments, two experiments examined the effects on heart rate (HR) of onset and offset of auditory stimulation in rats and of photic stimulation in guinea pigs. Experiment 1 demonstrated a unidirectional, decelerative response in rats 17 and 21 days of age to the onset and offset of a 1-kHz tone, at both low (80 dB) and high (100 dB) intensity levels and at 14 days to the onset of the high-intensity tone. Experiment 2 demonstrated that infant guinea pigs, which unlike infant rats are precocial and not nocturnal, responded to the offset but not to the onset of light, and that this response was decelerative. These results indicated a lack of generality of the bidirectional HR effect, and were discussed in terms of the orienting/defensive reflex distinction.     

Aggressive behavior inhibition by serotonin and quipazine injected into the amygdala in the rat

The effects on aggressive behavior, open-field activity, and pain threshold of bilateral microinjections of serotonin (20 micrograms) and quipazine (20 micrograms), the direct serotonergic receptor agonist, into the cortico-medial amygdala were investigated in Wistar rats. Both drugs significantly prolonged the attack latency in isolated killer rats (predatory aggression model), and suppressed the incidence of aggressive postures/attacks in shock-induced fighting test (affective aggression). The only difference in the open-field behavior was the lower number of central square entries in drug-treated compared to saline-injected rats. None of the substances produced any significant change in jump threshold. It is concluded that stimulation of serotonin receptors within the amygdala produces inhibition of affective and muricidal behavior in isolated rats. The effect does not seem to be dependent on changes in general activity and pain sensitivity.     

How personality relates to intelligence test performance: Implications for a theory of intelligence,ageing research and personality assessment

Previously reported findings indicate that variation of EEG evoked potential parameters is strongly related to both personality and intelligence differences (Robinson, 1982a, b). These data and the associated theory imply that personality should relate to intelligence test performance. Results are described in this report which indicate that subtest profiles obtained with the Wechsler Adult Intelligence Scale (WAIS) differ significantly for Ss scoring highest and lowest on the Extraversion (E) scale of the Eysenck Personality Questionnaire (EPQ); introverts tend to do better on the ‘Verbal’ subtests while extraverts tend to do better on the ‘Performance’ measures. Ss with middling scores on the E scale of the EPQ can also be distinguished in terms of specific WAIS profiles. In this case the results define two contrasting groups. Young male Ss with middling E scores tend to have high Psychoticism (P) and low Lie (L) scores on the EPQ as well as having distinctive WAIS profiles characterized by higher scores on subtests normally associated with a ‘Memory’ or ‘Attention-Concentration’ factor. Higher scores were also obtained by this subgroup on the Picture Arrangement and Block Design subtests which were previously shown to load a P + /L ? factor. The converse is true for older female Ss who also have middling E scores. As well as demonstrating a systematic relationship between personality and intelligence test performance these data provide some further support for a model of brain-behaviour relationships proposed by Robinson. Within this theoretical framework a neurophysiologically meaningful explanation can be provided for the three major factors that reliably emerge in factor-analytic studies of the WAIS. From an applied viewpoint, the data indicate that personality differences can be assessed from performance on tests such as the WAIS. On this issue the results are discussed with particular reference to Gittinger's Personality Assessment System. Implications for ageing research are also discussed.     

The pathological left-handedness syndrome

A clinical syndrome of pathological left-handedness (PLH) is proposed to identify the pattern of correlative changes in lateral development associated with early brain injury in some manifest left-handers. This syndrome is believed to be caused by a hemispheric lesion that is predominantly left-sided (or bilateral asymmetric), which onsets before Age 6, and which encroaches upon the critical speech zones of the frontotemporal/frontoparietal cortex. The pattern of changes may include any or all of the following features: shifts in manual dominance, trophic changes in the extremities, transfer of hemispheric speech, and/or intrahemispheric reorganization of visuospatial cognitive functions. Although some of these correlates of PLH have long been known, they have not been recognized as an interrelated pattern of traits that constitute a clinical syndrome. Identification of these individuals, all manifest left-handers, will be shown to have implications for diagnosis/remediation and for models of recovery of function.     

The relation between classroom social status and classmate likability,compromising skill,temperament, and neighborhood social interactions

Classmate likeability, compromising skill, and temperament (n = 135) and after-school patterns of social interaction (n = 101) were examined for third through seventh grade children who were identified by a binomial probability model as popular, rejected, neglected, or average in the classroom setting. Significant effects were obtained for each type of score. Compared to the other social status groups, popular children were the best liked and rejected children were the least liked; neglected and average children fell between these two extremes. Popular children had higher compromising scores than either rejected or average children, and neglected children had higher scores than rejected children. Compared to average children, rejected children had higher attention and rhythmicity temperament scores. Finally, popular and average children had more neighborhood friends than either rejected or average children, and meglected children had more younger neighborhood friends than did average children. Results are discussed in terms of models of peer social status.     

The effect of associations and expectations on lexical decision making in normals, alcoholics, and alcoholic Korsakoff patients

This study examined whether patients with Korsakoff's disease suffer from increased PI during encoding. The ability of the name of one category, e.g., BIRD, to prime the processing of members of another category, e.g., BODY PARTS, in a lexical decision task was used to assess the amount of PI during encoding. This task required a subject to inhibit the normal associations to BIRD. Young normals (25 years), older normals (48 years), alcoholics (45 years), and alcoholic Korsakoff patients (59 years) performed two lexical decision tasks. In the first experiment, the appearance of the neutral prime XXX 750 msec before the probe signaled that if the probe was a word, there was a 75% chance that it was from a particular category (e.g., BODY PARTS). The prime facilitated reaction time for words from the expected category for all four groups. The prime slowed reaction time for words that were not from the expected category for the young normals but did not influence reaction time for unexpected words for the three older groups. The second experiment was identical to the first except that a category word was used as the prime. The category word used as the prime was unrelated to the category of the words that were likely to follow it. For example, BIRD might be used to signal the likelihood that the word would be from the category, BODY PARTS. Again, young normals were slower to respond to unexpected probe words, but the three older groups were not. Again, the prime facilitated reaction time for expected words for the young normals, older normals, and alcoholics. However, the word prime did not facilitate reaction time for expected words for the alcoholic Korsakoff patients. That the word prime did not facilitate reaction time for the Korsakoff patients was viewed as evidence that they were unable to inhibit its normal associations and were more sensitive to PI from these associations than the other subjects.     

Disqualified and qualified poor sleepers: subjective and objective variables

Sleep laboratory studies of patients complaining of insomnia have demonstrated discrepancies between subjective reports and electroencephalograph (EEG)-recorded measures. In our research studies on sleeping aids, 60% of the self-described poor sleepers who reported usual sleep latencies of at least 45 min did not meet the laboratory qualification criterion of a 30-min or longer sleep latency. To learn to predict who would qualify for our studies, we compared 30 laboratory-qualified poor sleepers (QPS) with 30 laboratory-disqualified poor sleepers (DPSs) on subjective report, mood, and all-night sleep laboratory variables. QPSs had significantly lower sleep efficiency and total sleep time in the laboratory, but these differences were due to the longer sleep latencies (50.7 +/- 27.8 min vs. 15.2 +/- 6.1 min) of the QPS group. QPSs and DPSs differed significantly in their morning estimates of their laboratory sleep latencies; as a group, QPSs gave an accurate estimate (51.6 +/- 27.8 min), but DPSs were significantly more likely to exaggerate their sleep latencies. Although we did not identify ways of predicting which poor sleepers would show sleep-onset insomnia in the sleep laboratory, we did find that, in this young, healthy population, there are poor sleepers who give an accurate report of a rather severe sleep-onset insomnia.     

The inequivalence of self-reports of Type A behavior: Differential relationships of the Jenkins Activity Survey and the Framingham cale with affect,stress, and control

The Jenkins Activity Survey (JAS) and the Framingham Type A Scale (FTAS) have been found to have different psychological correlates. The JAS is typically unrelated to anxiety, while the FTAS is consistently correlated with trait anxiety. The present study of 200 male and female college students clarifies further the psychological heterogeneity of these measures. Enhanced motivation to control the environment has been suggested as an underlying psychological component of Type A behavior (Glass, 1977). Dysphoric emotions and the perception of more environmental stresses, on the other hand, are typical of neuroticism or negative affectivity (Watson & Clark, 1984). Although the results indicate that the JAS and FTAS are highly correlated, the JAS is more closely related to control motivation than is the FTAS. Further, compared to the JAS, the FTAS is more closely correlated with dysphoric emotions and perceived daily stresses. Thus, the results indicate that the JAS is closely correlated with core psychological components of the Type A pattern, while the FTAS has a relatively unique association with general emotional distress. Such differences may account for the fact that these measures are related to different disease end points.