Experiences with the indirect Clausen Test using NTA as an antigen in multiple sclerosis and other neurologic diseases

The present study based on the indirect Clausen-test using NTA and PHA as antigens contributed to therapy control and possibly prognosis assessment rather than to immunological differential diagnosis.     

Catamnestic surveys on somato-psychosocial development in childhood and adolescence of patients with unipolar depressive and bipolar manic-depressive psychoses

The somatic and psychosocial development of 80 subjects with manifest affective-phasic psychoses is studied retrospectively and compared with that of an identically sized control group consisting of neuropsychiatrically healthy subjects. Statistically significant differences were found particularly in the answers to questions dealing with social situation and social adaptability. Achievement at school and vocational qualifications were lower among the parents of the patients than among those of the healthy subjects. Characteristic features of the patients' childhood and adolescence were transient depression, often for no apparent cause, and maladaption, and vocational wishes were fulfilled less often than among the controls. The patients experienced greater difficulty in settling in to a new group due to their contact difficulties.     

Acoustically evoked brain stem potential in Wilson disease

By 48 patients with Wilson's disease the brainstem acoustic evoked potentials were stated. There were 35 pathological findings (73%), 13 were normal (27%). The waves, determined by the middle and upper brainstem (Pons and Mesencephalon) showed most of all pathological changes. Those patients with forms of Wilson's disease called Pseudoskelerose and Pseudoparkinson showed the most pathological findings. But one could watch these findings by about 30% of patients in preclinical stage. This method can possibly be used for early detection of disorders of brainstem functions and in the same way it can be used for control of treatment by patients in preclinical stage.     

Value of mechanographic studies in neuromuscular function diagnosis

Mechanographic examinations have hitherto played only a minor role in general clinical neuromuscular functional diagnostics. The purpose of this contribution is, therefore, to present an appropriate recording apparatus (W. Zett , 1969), to report on the values that can be considered normal and to outline the diagnostic value of the method using clinical applications as examples. Special value is attached to simultaneous recording of the EMG and the mechanograph because this method permits differentiated conclusions to be drawn regarding disturbances in muscular activity, the electromechanical coupling and the actual process of contraction. The method is also important for pharmacological investigations and should be used principally in connection with musclepathology for objectifying the effects of medication.     

Influence of prolonged deprivation,age and culture on the development of future orientation

Prolonged deprivation and future orientation (FO) were studied in 200 Indian and Nepalese students of 14–16 and 18–20 years with verbal measures. In both cultures low deprived subjects were significantly more future-oriented. In the development of FO both age and deprivation were significant with experiential aspect of socialization exerting greater influence than physico-economic deprivation.     

Mental extrapolation in patterns constructed from memory

Finke and Pinker (1982, 1983) showed subjects an array of dots followed by an arrow in a blank field, and asked them to determine whether the arrow pointed to any of the previously seen dots. Response times were linearly related to the distance between the arrow and the nearest dot, suggesting that subjects spontaneously used an internal scanning or extrapolation process to perform the task. We replicate and extend this finding by varying the retention interval, and by employing a paradigm in which subjects’ eyes are closed and the arrows are described to them using a coordinate scheme. We also show that subjects are unable to predict the form of the data when the task simply is described to them. Results suggest that mental scanning along a straight path can be performed on images reconstructed from memory, and that it does not depend on the ongoing perception of a continuous surface, on physical eye movements, or on demand characteristics.     

Effects of family therapy for substance abuse: A systematic review of recent research

One of the most serious psychosocial problems worldwide is substance abuse because of its repercussions not only on the physical and psychological health of the abuser but also on their relational functioning. Among the well-established therapeutic approaches for the treatment of substance abuse is family therapy, which, in addition to influencing personal variables, promotes changes in family dynamics. The main objective of this study is to review the scientific literature published from 2010 to the present on the efficacy and effectiveness shown by family-based treatment approaches for substance use problems both in adolescent and adult samples. In addition, the effect on secondary variables such as family functioning and behavioral problems is evaluated. The empirical evidence accumulated in the last decade and reviewed in the present study indicates that the incorporation of family members in the treatment of substance abuse produces benefits by diminishing consumption and improving family functioning. Limitations of this study and of the research reviewed are discussed and directions for future research are provided.