Is there an optimal factor structure of the Positive and Negative Syndrome Scale in patients with first‐episode psychosis?

The Positive and Negative Syndrome Scale (PANSS) is the most widely used scale to assess a variety of symptoms in patients with schizophrenia and other psychoses. The factor structure of the PANSS has been examined with confirmatory factor analyses in several studies, but not in a well‐defined first‐episode psychosis sample. The aim of this paper is to examine the statistical fit of five different PANSS models in a first‐episode, non‐affective psychosis sample. Confirmatory factor analyses were performed on PANSS data (n = 588). A main criterion for best fit was defined as the Expected Cross Validation Index (ECVI). No tested model revealed an optimally satisfactory model fit index. The Wallwork/Fortgang five‐factor model demonstrated the most optimal psychometric properties. The corresponding subscales of all evaluated five‐factor models were strongly intercorrelated. The Wallwork/Fortgang five‐factor model was found to be statistically and clinically ideal among patients with first‐episode psychosis. Therefore, we recommend this model in forthcoming studies among patients with first‐episode psychosis. However, to prevent the loss of clinically valuable information on an item level, we do not recommend removing any items from the original form. Our study also implies that the specific choice of model will not have a substantial effect on outcome results in studies on the course and outcome in first‐episode psychosis.     

Dichotic listening,executive functions and grey matter cortical volume in patients with schizophrenia and healthy controls

Schizophrenia is characterized by cognitive impairment, especially in relation to executive functions. Brain structural abnormalities are also often seen in schizophrenia although little is known of the relationship between cognitive impairment and structural brain changes. Our aim was therefore to investigate this relationship further using MRI and a dichotic listening (DL) task with simple speech sounds and with instructions to focus attention and report only from the left or right ear stimulus. When instructed to focus attention on the left ear syllable a cognitive conflict is induced requiring the allocation of executive resources to be resolved. Grey matter (GM) volume was measured with MRI from four volumes of interests (VOIs), left and right frontal and temporal cortex, respectively, and correlated with DL performance. The results showed significant differences between the groups in their ability to focus attention on and report the left ear stimulus, which was accompanied by reduced GM volume in the left frontal and right temporal lobe VOIs. There was also a significant positive correlation between left frontal GM volume and performance on the DL task, for the groups combined. The results did not support a conclusion that an impairment in cognitive function in schizophrenia was driven by an corresponding impairment in brain structure, since there were no significant correlations when the groups were analyzed separately. It is however concluded that patients with schizophrenia are impaired in executive functions and that they also show reduced GM volumes in left frontal and right temporal lobe areas, compared to healthy controls.     

In-group ratings are affected by who asks and how: interactive effects of experimenter group-membership and response format

In three experiments, participants rated how well a number of adjectives described their in-group (e.g. kind-hearted, helpful, intelligent, efficient, etc.). In Experiment 1, females were found to rate their ingroup (females) more favorably when reporting verbally to female (rather than male) experimenters. This finding was further explored in two subsequent experiments where response format (written vs. verbal) was also manipulated. Both experiments revealed an interaction such that ethnic Swedes rated their in-group (Swedes) the most favorably when reporting verbally to an in-group experimenter and the least favorably when reporting verbally to a Middle Eastern experimenter. Results are discussed in relation to correction and contextual activation of social norms.     

A randomized study of the impact of a sensitizing intervention on the child‐rearing attitudes of parents of low birth weight preterm infants

Nordhov, S. M., Kaaresen, P. I., Rønning, J. A., Ulvund, S. E. & Dahl, L. B. (2010). A randomized study of the impact of a sensitizing intervention on the child‐rearing attitudes of parents of low birth weight preterm infants. Scandinavian Journal of Psychology, 51, 385–391. The background for this study was that nurturant child‐rearing attitudes are associated with positive development in low birth weight (LBW) infants. The objective was to study child‐rearing attitudes and early intervention (EI) in parents of LBW infants from 12–36 months corrected age. LBW infants (BW < 2000 g) were randomized to an intervention (IG) or a control group (CG). The EI consisted of seven in‐hospital sessions prior to discharge, then four home visits. A Child Rearing Practices Report was administered at 12 (mothers only), 24 and 36 months. A total of 146 infants were randomized. The mean BW in IG was 1396 (SD 429) g and 1381 (436) g in CG. The mean GA was 30.2 (3.1) weeks in IG and 29.9 (3.5) weeks in CG. Mothers in IG reported significantly more nurturant child‐rearing attitudes at 12 and 24 months. There was a significant change in restrictive and nurturant attitudes over time. It was concluded that EI may lead to more nurturant child‐rearing attitudes in mothers of preterms.     

Effect of low dose ionizing radiation exposure in utero on cognitive function in adolescence

Heiervang, K. S., Mednick, S., Sundet, K. & Rund, B. R. (2010). Effect of low dose ionizing radiation exposure in utero on cognitive function in adolescence. Scandinavian Journal of Psychology, 51, 210–215. Radiation from the Chernobyl nuclear power plant meltdown greatly affected several Norwegian counties. The cognitive consequences of in utero exposure to radiation from the Chernobyl accident have been intensely debated. This study examines the cognitive outcomes for those Norwegians who were exposed as fetuses to the fallout from Chernobyl. The participants, 84 adolescents who were exposed in utero to radiation from the most contaminated areas in Norway and 94 adolescents from areas not contaminated by the radiation, were tested on verbal and nonverbal IQ. Two data analyses were conducted. First, using a control‐group design, the IQ scores of exposed and unexposed adolescents were compared. Second, in a timing‐of‐exposure design, those exposed during the most sensitive period were contrasted with those exposed later in gestation. Adolescents exposed to low‐dose ionizing radiation in utero scored significantly lower in full‐scale IQ than unexposed adolescents. The difference was restricted to verbal IQ and was not evident for nonverbal IQ. The effect was not observed in exposed adolescents who had passed the most sensitive gestational period prior to the accident and thus were exposed to the radiation from Chernobyl exclusively after gestational week 16. These participants performed as well as the controls. Although the results should be interpreted cautiously due to the study’s nonrandomized design, the data add new and important support to the hypothesis that the Chernobyl accident may have had a subtle effect on the cognitive functioning of those exposed to low‐dose ionizing radiation in utero during the most sensitive gestational period.     

Epistemological Challenges to Mathematical Platonism

Since Benacerraf’s “Mathematical Truth” a number of epistemological challenges have been launched against mathematical platonism. I first argue that these challenges fail because they unduely assimilate mathematics to empirical science. Then I develop an improved challenge which is immune to this criticism. Very roughly, what I demand is an account of how people’s mathematical beliefs are responsive to the truth of these beliefs. Finally I argue that if we employ a semantic truth-predicate rather than just a deflationary one, there surprisingly turns out to be logical space for a response to the improved challenge where no such space appeared to exist.     

Withholding and Withdrawing Life-Sustaining Treatment: Ethically Equivalent?

Withholding and withdrawing treatment are widely regarded as ethically equivalent in medical guidelines and ethics literature. Health care personnel, however, widely perceive moral differences between withholding and withdrawing. The proponents of equivalence argue that any perceived difference can be explained in terms of cognitive biases and flawed reasoning. Thus, policymakers should clear away any resistance to accept the equivalence stance by moral education. To embark on such a campaign of changing attitudes, we need to be convinced that the ethical analysis is correct. Is it? In this article, I take a closer look at the moral relation between withholding and withdrawing. My conclusion is that withholding and withdrawing are not in general ethically equivalent. Thus, medical guidelines should be rewritten, and rather than being “educated” away from their sound judgments, medical professionals and patients should have nuanced medico-ethical discussions regarding withholding and withdrawing treatment.     

HOW TO ANALYZE IMMEDIATE EXPERIENCE:

Abstract: This article discusses Jaakko Hintikka's interpretation of the aims and method of Husserl's phenomenology. I argue that Hintikka misrepresents Husserl's phenomenology on certain crucial points. More specifically, Hintikka misconstrues Husserl's notion of “immediate experience” and consequently fails to grasp the functions of the central methodological tools known as the “epoché” and the “phenomenological reduction.” The result is that the conception of phenomenology he attributes to Husserl is very far from realizing the philosophical potential of Husserl's position. Hence if we want a fruitful rapprochement between analytical philosophy and Continental phenomenology of the kind that is Hintikka's ultimate aim, then Hintikka's account of Husserl needs correcting on a number of crucial points.