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Attention-Deficit/Hyperactivity Disorder (ADHD) is related to suboptimal decision making in experimental tasks and to real-life risk-taking behavior (RTB) such as substance abuse and unsafe traffic conduct. In this preregistered study, we tested whether these associations are mediated by need for cognition—the extent to which one tends towards, and enjoys, analytical thought. In a large sample of young adults (N = 463, Mage = 19.7 years), we tested whether need for cognition mediated the association between self-reported ADHD symptoms on the one hand and decision-making strategy complexity on an experimental gambling task and self-reported real-life RTB on the other hand. Preregistered confirmatory analyses indicated first that ADHD symptoms were positively associated with real-life RTB, but the association was not mediated by need for cognition. Second, ADHD symptoms were not related to decision-making strategy complexity, and need for cognition was not a significant mediator. Explorative analyses revealed that (a) need for cognition was associated with higher decision-making accuracy and slower reaction time; (b) need for cognition was related to inattentive but not to hyperactive/impulsive ADHD symptoms; (c) need for cognition was associated with health-related RTB but not interpersonal RTB; and (4) only the association between inattention and health-related RTB was mediated by need for cognition. We conclude that need for cognition is not a mediator in the association between ADHD symptoms and RTB. Additionally, we conclude that neither ADHD symptoms nor need for cognition predict decision-making strategy complexity. Implications for both future research and clinical practice are discussed. 相似文献
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Kindling-induced changes in plasticity of the rat amygdala and hippocampus 总被引:3,自引:0,他引:3 下载免费PDF全文
Schubert M Siegmund H Pape HC Albrecht D 《Learning & memory (Cold Spring Harbor, N.Y.)》2005,12(5):520-526
Temporal lobe epilepsy (TLE) is often accompanied by interictal behavioral abnormalities, such as fear and memory impairment. To identify possible underlying substrates, we analyzed long-term synaptic plasticity in two relevant brain regions, the lateral amygdala (LA) and the CA1 region of the hippocampus, in the kindling model of epilepsy. Wistar rats were kindled through daily administration of brief electrical stimulations to the left basolateral nucleus of the amygdala. Field potential recordings were performed in slices obtained from kindled rats 48 h after the last induced seizure, and in slices from sham-implanted and nonimplanted controls. Kindling resulted in a significant impairment of long-term potentiation (LTP) in both the LA and the CA1, the magnitude of which was dependent on the number of prior stage V seizures. Saturation of CA1-LTP, assessed through repeated spaced delivery of high-frequency stimulation, occurred at lower levels in kindled compared to sham-implanted animals, consistent with the hypothesis of reduced capacity of further synaptic strengthening. Furthermore, theta pulse stimulation elicited long-term depression in the amygdala in nonimplanted and sham-implanted controls, whereas the same stimulation protocol stimulation caused LTP in kindled rats. In conclusion, kindling differentially affects the magnitude, saturation, and polarity of LTP in the CA1 and LA, respectively, most likely indicating an activity-dependent mechanism in the context of synaptic metaplasticity. 相似文献
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Hübner M Dreisbach G Haider H Kluwe RH 《Journal of experimental psychology. Learning, memory, and cognition》2003,29(2):289-297
Endogenously initiated transitions between tasks are associated with inhibition of the attentional set for the task preceding the transition, as demonstrated by slowed reactions to a task most recently switched away from (U. Mayr & S. W. Keele, 2000). Using an altered methodological approach, the authors found that this backward inhibition counteracts perseverative tendencies when switching to a new task in that it selectively reduces interference exerted by the preceding task set. The reduction of interference was dependent on endogenous preparation for the new task and did not occur for unpredictable task switches or for task switches that were precued without information about the identity of the new task. 相似文献
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Hilde M. Huizenga Ruud WetzelsDon van Ravenzwaaij Eric-Jan Wagenmakers 《Organizational behavior and human decision processes》2012
According to Unconscious Thought Theory, people make better decisions after unconscious than after conscious thought (Dijksterhuis, Bos, Nordgren, & van Baaren, 2006a). Unconscious Thought Theory yields four specific predictions. First, an exact replication of Dijksterhuis et al. (2006a) study should indicate that unconscious decisions are superior to conscious decisions. Second, decisions should improve with duration of conscious thought. Third, unconscious decisions should be superior to conscious decisions, even if unconscious decisions are deliberated while having access to information. Fourth, unconscious decisions should be based on a weighting strategy. We report results of four studies, featuring 480 participants, that yield no evidence in favor of these predictions. Therefore our findings cast doubt on Unconscious Thought Theory and its advice to base decisions on unconscious thought. The results of our studies suggest that it is better to base decisions on conscious thought while having access to information. 相似文献
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Charts of 125 adults (18 to 82 years), referred to an autism expert team for Autism Spectrum Disorder (ASD) assessment, were reviewed to explore the pathway to an adulthood ASD diagnosis. The participants first contacted the mental health care clinic at a median age of 19 years (range 2 to 78 years). Men contacted the clinic slightly earlier than women. The main referral reasons were social problems, feelings of anxiety and mood disturbances. The most common earlier diagnoses were anxiety and mood disorders or psychosis-related disorders. These diagnoses were more common in women than in men. Surprisingly few differences emerged between those who finally received an ASD diagnosis and those who did not. However, those with an ASD diagnosis contacted the clinic a mean of 15 years earlier and less frequently received different former diagnoses, although the type of diagnoses did not differ. The diagnostic criteria that were prevalent during early childhood of these adults did not influence their diagnostic history. A quarter of these clients were known with social problems within the mental health care system, but ASD was not assessed. Hence, the current study shows that the pathways to an adulthood ASD diagnosis are very heterogeneous. 相似文献
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In this article, the authors investigate the assumption that preparation while switching between cognitive tasks is dynamically
adjusted to the current task demands. Performance in high-shift blocks (75% shifts) was compared with performance in high-repetition
blocks (75% repetitions). This probability information was given either at the beginning of a block (global condition) or
by specific probability cues before every trial (local condition). The authors report strong preparation effects (activation
of the probable task and inhibition of the improbable task) in high-shift blocks, especially when specific probability cues
were provided. In high-repetition blocks, however, the preparation effects were less pronounced. The results support the assumption
that preparation is dynamically adjusted to the expected task requirements. 相似文献
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Lindemann H 《The American journal of bioethics : AJOB》2006,6(2):W15-W19
I argue that the field of bioethics is gendered feminine, but that the methods it uses to resist this gender identity pose real harm to actual women. Starting with an explanation of what I take 'gender' to be, I enumerate four drawbacks to being gendered feminine. I then argue that bioethics suffers from three of the same four drawbacks. I show how the field escapes the fourth disadvantage by adopting a masculine persona that inflicts damage on women, and conclude by urging bioethicists to reflect on their complicity in abusive power systems such as gender, race and class. 相似文献