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1.
Linda J Koenig Sherri L Pals Tim Bush Melody Pratt Palmore Dale Stratford Tedd V Ellerbrock 《Health psychology》2008,27(2):159-169
OBJECTIVE: Compare the efficacy of a multicomponent social support intervention to standard-of-care counseling on medication adherence among HIV-infected patients initiating antiretroviral therapy. DESIGN: Randomized controlled trial. Generalized estimating equations tested for differences in the percentage of participants achieving 90% adherence. MAIN OUTCOME MEASURES: Pill-taking, electronically monitored over 6 consecutive months; plasma viral load (VL), assessed at 3 and 6 months following initiation of therapy. RESULTS: Of 226 participants who were randomized and began the trial, 87 (38%) were lost to the study by 6 months. The proportion of adherent participants declined steadily over time, with no time by group interaction. Sustained adherence was associated with increased odds of achieving an undetectable VL (OR=1.78; 95% CI=1.01, 3.13). In intention-to-treat analyses, a larger proportion of the intervention group than the control group was adherent (40.15% vs. 27.59%, p=.02) and achieved an undetectable VL p=.04). However, the majority of participants who remained on study experienced some reduction in VL (>or=1-log drop or undetectable), regardless of experimental condition. CONCLUSION: The multicomponent social support intervention significantly improved medication adherence over standard-of-care counseling; evidence for improved virologic outcomes was inconsistent. Early discontinuation of care and treatment may be a greater threat to the health of HIV patients than imperfect medication-taking. 相似文献
2.
Rebecca Logsdon Larry Hochhaus Harold L. Williams O.H. Rundell Dale Maxwell 《Acta psychologica》1984,55(2):179-193
An experiment which employed each of 18 subjects in four days of testing was used to examine acute secobarbital dose treatment effects on choice reaction time in a Cooper and Shepard (1973) character recognition task. Manipulations of visual stimulus degradation, character difficulty, 180 degree rotation, and mirror-image reversal were included in order to evaluate the hypothesis that the drug affects performance by disrupting early stimulus input processing. The results indicate significant increases in the effect of secobarbital on reaction time and errors under conditions of visual stimulus degradation. The effects of the drug, however, were not changed by 180 degree rotation of the target character or by the other task variables. The results were interpreted to indicate that secobarbital impairs performance primarily by placing selective stress on hypothetical early encoding activities and that later processing operations (associated with use of an internal representation of the target character) are not affected by the drug. Strengths and weaknesses of the two-stage model of visual stimulus processing are discussed and implications of the model for future drug research are indicated. 相似文献
3.
Though many studies have examined the predictive power of expressed choices versus that of measured interests, fewer have been concerned with the relationship between the degree to which choices and interests agree and later persistence in an expressed choice. This study explored that relationship, using longitudinal data for 7706 college students and 1372 employed persons. Four levels of congruence between expressed choice and measured interests were identified. Results indicated that persistence in an expressed choice increases systematically as congruence between choice and interests increases. Implications for counselors are noted. 相似文献
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A battery of information processing measures and psychometric tests of specific and general cognitive abilities was administered to a sample of 105 individuals which included 34 monozygotic and 13 dizygotic reared apart twin pairs or triplets. Correlations between information processing parameters and psychometric abilities as well as twin resemblances for the information processing parameters were examined. In a principal components analysis of the information processing parameters, three components were identified which accounted for 67% of the total variation; Overall Speed of Response (OSR), Speed of Information Processing (SIP), and Speed of Spatial Processing (SSP). OSR was significantly correlated with WAIS IQ, and psychometric measures of verbal reasoning, spatial ability, and perceptual speed and accuracy. SIP was significantly correlated with WAIS IQ, measures of verbal reasoning, and one of the perceptual speed and accuracy measures. SSP was significantly correlated with measures of both spatial ability and perceptual speed and accuracy. Due to the small size of the dizygotic twin sample, no strong conclusions could be drawn regarding the magnitude of their resemblance. The correlation between component scores of reared apart monozygotic twins was significant for OSR, but not for SIP or SSP. 相似文献
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People use editorial criteria to decide whether to say or to suppress potential arguments. These criteria constitute people's standards as to what effective and appropriate arguments are like, and reflect general interaction goals. A series of empirical investigations has indicated that the standards fall into three classes: those having to do with argument effectiveness, those concerned with personal issues for arguer and target, and those centered on discourse quality. The essay also sketches the affinities certain types of people have for the different criteria. 相似文献
7.
Dale Prediger Kyle Swaney Wei-Cheng Mau 《Journal of counseling and development : JCD》1993,71(4):422-428
Since its introduction nearly 25 years ago, Holland's (1985) hexagon has remained in skeletal form. The hexagon is used to depict similarities and differences among occupations—but only six general types of occupations. The authors show in this article how to extend the basic concepts embodied in the hexagon. Procedures for locating counselees and occupations on the hexagon are illustrated. These procedures, which are compatible with scores from a wide variety of assessment instruments, can help counselees identify and explore occupational options. The authors also report research on the hexagon locations of 27 career groups. 相似文献
8.
Benefits of humor in reduction of threat-induced anxiety 总被引:2,自引:0,他引:2
The benefits of humor in reducing anxiety were investigated in a laboratory study, in which subjects were falsely led to believe that they would receive a shock in 12 min. Participants were 53 undergraduate students with either high or low sense of humor as measured by the Situational Humor Response Questionnaire of Martin and Lefcourt (1984). During the anticipatory period, subjects listened to either a humorous tape, a nonhumorous tape, or no tape. Dependent variables were repeated measures of self-reported anxiety, heart rate, and zygomatic facial activity. Anxiety increased over the anticipatory period, as predicted. A significant interaction between condition and time indicated that subjects from the humor condition consistently rated themselves as less anxious and reported less increase in stress as the shock approached. A three-way interaction concentrating on the final 3 min. indicated a tendency for subjects with low sense of humor to have higher heart rates in the no-tape condition than in the humorous or nonhumorous tape conditions. Analysis for zygomatic activity indicated more smiling by subjects with high sense of humor and by subjects in the humor condition. Also, the humorous tape elicited more smiling by subjects with high sense of humor. 相似文献
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