Cartesian or condillacian linguistics?

This paper intends to deal with Condillacian Linguistics. Although the Condillacian philosophy of mind and analysis of language were the most important in the late eighteenth century, none of them is mentioned in Chomsky's work (1966, Cartesian Linguistics). It would be useful for the history of Western thought if Chomsky's monumental error were generally recognized and if Condillacian Linguistics were at last to find the place it rightly deserves. The main thesis of Condillac's linguistic ideas (language is the first step in the analysis of thought) is briefly presented with reference to its context and consequences.     

Hippocampal damage and exploratory preferences in rats: memory for objects, places, and contexts

Rats have a natural tendency to spend more time exploring novel objects than familiar objects, and this preference can be used as an index of object recognition. Rats also show an exploratory preference for objects in locations where they have not previously encountered objects (an index of place memory) and for familiar objects in contexts different from those in which the objects were originally encountered (an index of context memory). In this experiment, rats with cytotoxic lesions of the hippocampal formation were tested on all three versions of the novelty-preference paradigm, with a 5-min retention interval between the familiarization and test phases. Rats with sham lesions displayed a novelty preference on all three trial types, whereas the rats with hippocampal lesions displayed a novelty preference on Object trials but did not discriminate between the objects on Place trials or Context trials. The findings indicate that hippocampal damage impairs memory for contextual or spatial aspects of an experience, whereas memory for objects that were part of the same experience are left relatively intact.     

The paradox of quetiapine in obsessive-compulsive disorder

Schizophrenia and obsessive-compulsive disorder (OCD) have historical, clinical, and epidemiological links. The clinical use of atypical neuroleptics (ie, dual serotonin-dopamine antagonists) to treat both conditions sheds a new light on them. We report the first two cases of obsessive-compulsive symptoms (OCS) induced by quetiapine in schizophrenia patients. A case of successful augmentation by quetiapine in refractory OCD is also presented. A review of the literature on OCS induced by atypical neuroleptics follows. This paradoxically induced OCD symptomology in schizophrenia patients administered atypical neuroleptics is discussed from new pathophysiological and clinical perspectives. The discussion emphasizes the prognostic implications of OCS in schizophrenia and available therapies for this comorbidity.     

Tolerant macaque species are less impulsive and reactive

Animal Cognition - Inhibitory control, the inhibition of impulsive behaviours, is believed to be key in navigating a complex social environment. Species characterised by higher social tolerance,...     

Lost in Translation? The Need for ‘Upstream Engagement’ with Nanotechnology on Trial

Nowadays, the criticism of the so-called ‘deficit model’ and the need for ‘upstream engagement’ in science and technology are becoming part of the master narratives of public policies in many countries, especially concerning nanotechnology. This may be considered as a major success for STS scholars, whose research results have largely contributed to this change, especially those concerning the GMO controversies. Some STS scholars thus move from a position of distant and critical observers to the role of experts in social engineering or advisers of policy-makers. However, in their enthusiasm concerning the expected benefits of upstream engagement, institutions, TA practitioners and social scientists seem to ignore some important limitations as well as the implicit framing assumptions of the concept. Based on an experience made by a group of social scientists in the Grenoble area—one of the major ‘nanodistricts’ in Europe—our paper shows that the ‘upstream engagement’ concept is still embedded in a linear model of innovation and is not very useful to anyone pursuing the co-production of innovations. It is especially true when socio-technical networks are already aligned by powerful actors and a worldwide agenda as in the case of nanotechnology. In order to give an opportunity for public engagement to have a larger impact on decision-making, we propose an alternative approach, which combines Actor–Network Theory (ANT), as an analytical tool, with the reflexive and ongoing implementation of public participation. Public engagement is probably one of the critical loci where STS scholars must reflect on the articulation between the knowledge they produce and public policies in action.     

Interactive-Virtual Reality (IVR) Exercise: An Examination of In-Task and Pre-to-Post Exercise Affective Changes

In this research, we examine the influence of imposed vs. self-chosen interactive/virtual reality (IVR) exercise on affect response following, as well as during, exercise. Our sample included 131 university students who were assigned to one of three 10-min conditions: (a) self-selected interactive/virtual reality (IVR) exercise, (b) externally imposed IVR exercise, or (c) regular exercise. Exercise intensity was standardized in terms of metabolic benchmarks. Mood benefits were observed pre-to-post exercise regardless of condition. During exercise, however, higher pleasure ratings were reported by participants in the self-selected IVR exercise condition. The implications of the immediate mood effects of self-selected IVR exercise are discussed.     

Catholic Reflections for an Updated Donum Vitae Instruction: A New Catholic Challenge in a Post-Christian Europe

On February 22, 1987, the Congregation for the Doctrine of theFaith published the Donum Vitae Instruction. Twenty years later,on February 22, 2007, Pope Benedict XVI asked for an updateof this Instruction. According to the Donum Vitae Instructionof 1987, the principle of the holiness of life imposes respectfor human persons from the very beginning of human life. Inthese past 20 years, new medical techniques have raised freshethical issues that are to be addressed by the Roman CatholicChurch Magisterium. The Roman Catholic Church, in its updateof the Instruction planned for 2007, will have to explain howcivil law is to be regulated according to the fundamental normsof the moral law. The moral message of the new Donum Vitae (justas in the 1987 version) will be to affirm the substance of humanjustice: respect for human life, as expressed in the resolvenot to infringe on, or to protect such life. Even in a post-ChristianEurope, this theological message can be understood if it istrue that Europe is marked by the principle of the absoluteprotection of human life.