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Susan S Girdler Jane Leserman Robertas Bunevicius Rebecca Klatzkin Cort A Pedersen Kathleen C Light 《Health psychology》2007,26(2):201-213
OBJECTIVE: To examine dysregulation in biological measures associated with histories of abuse in women and whether women with premenstrual dysphoric disorder (PMDD) differ in their dysregulation. DESIGN: Twenty-five women meeting prospective criteria for PMDD and 42 non-PMDD controls underwent structured interview to determine abuse histories and lifetime Axis I diagnoses, excluding those with current Axis I disorders or using medications. MAJOR OUTCOME MEASURES: Plasma cortisol and norepinephrine (NE), heart rate (HR), blood pressure (BP), and vascular resistance index (VRI) were assessed at rest and in response to mental stress. RESULTS: A greater proportion of PMDD women had prior abuse compared with non-PMDD women. Regardless of PMDD status, all abused women had lower plasma NE and higher HRs and tended to have lower plasma cortisol at rest and during stress. Abused women also reported more severe daily emotional and physical symptoms. Greater VRI and BP at rest and during stress were seen only in PMDD women with abuse. CONCLUSION: There is persistent dysregulation in stress-responsive systems in all abused women that cannot be accounted for by current psychiatric illness or medications, and PMDD women may be differentially more vulnerable to the impact of abuse on measures reflecting alpha-adrenergic receptor function. 相似文献
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Tavis S Campbell Blaine Ditto Jean R Séguin Jean-Marc Assaad Robert O Pihl Daniel Nagin Richard E Tremblay 《Health psychology》2002,21(6):594-600
A growing literature has observed a significant reduction in pain sensitivity among hypertensive animals and humans. It is uncertain whether a reduced sensitivity to pain can be observed in nonnotensive individuals who go on to develop high blood pressure. Blood pressure (BP) was reassessed in one hundred fifteen 19-year-old boys initially tested at age 14, when they were also presented with a pain stimulus (mechanical finger pressure). Hierarchical regression analyses indicated that information regarding pain tolerance improved prediction of changes in systolic and diastolic blood pressure beyond that afforded by differences in BP at age 14, parental history of hypertension, and body mass index. These analyses suggest that pain sensitivity may be associated with physiological processes involved in the development of sustained high blood pressure. 相似文献
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Alan Garnham Jane Oakhill Kate Cain 《The Quarterly Journal of Experimental Psychology Section A: Human Experimental Psychology》1997,50(1):149-162
Two experiments investigated the interpretation of anaphoric noun phrases, and in particular those thatcould only be linked to their antecedents via knowledge-based inferences. The first experiment showed that much of the inferential processing was carried out as the anaphoric noun phrase was read, although there was some indication that inferential processing continued to the end of the clause. The second experiment attempted to establish why anaphoric noun phrases that are more specific than their antecedents cause problems. It showed that the difficulty did not lie in adding the extra information carried by the anaphor to the representation of the referent. Rather, we suggest, putting extra information in the anaphoric noun phrase disrupts the process of linking that noun phrase to its antecedent. 相似文献
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Noelle Yuen Naleen Andrade Linda Nahulu George Makini John F. McDermott George Danko Ronald Johnson Jane Waldron 《Suicide & life-threatening behavior》1996,26(1):27-36
Native Hawaiian high school students, N = 1779, were surveyed for symptoms of psycho-pathology and suicide attempts in the previous 6 months. Seventy-seven (4.3%) of the students reported making a suicide attempt. There were no significant differences in prevalence rates for males and females. Depression, anxiety, aggression, substance abuse symptoms, and low family support, but not peer support, were significantly correlated with suicide attempts. On logistic regression, depression, substance abuse, and family support independently predicted attempts. The lack of gender difference may indicate a cultural characteristic of the Hawaiian population that differentiates it from mainstream American populations but likens it to the Native American population. 相似文献