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Ed H. B. M. Gronenschild Floortje Smeets Eric F. P. M. Vuurman Martin P. J. van Boxtel Jelle Jolles 《Behavior research methods》2009,41(4):1053-1060
In psychological experiments involving facial stimuli, it is of great importance that the basic perceptual or psychological
characteristics that are investigated are not confounded by factors such as brightness and contrast, head size, hair cut and
color, skin color, and the presence of glasses and earrings. Standardization of facial stimulus materials reduces the effect
of these confounding factors. We therefore employed a set of basic image processing techniques to deal with this issue. The
processed images depict the faces in gray-scale, all at the same size, brightness, and contrast, and confined to an oval mask
revealing only the basic features such as the eyes, nose, and mouth. The standardization was successfully applied to four
different face databases, consisting of male and female faces and including neutral as well as happy facial expressions. An
important advantage of the proposed standardization is that featural as well as configurational information is retained. We
also consider the procedure to be a major contribution to the development of a de facto standard for the use of facial stimuli
in psychological experiments. Such methodological standardization would allow a better comparison of the results of these
studies. 相似文献
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Jacobs HI Van Boxtel MP Uylings HB Gronenschild EH Verhey FR Jolles J 《Brain and cognition》2011,75(2):154-163
Cortical grey matter atrophy patterns have been reported in healthy ageing and Alzheimer disease (AD), but less consistently in the parietal regions of the brain. We investigated cortical grey matter volume patterns in parietal areas. The grey matter of the somatosensory cortex, superior and inferior parietal lobule was measured in 75 older adults (38 cognitively stable and 37 individuals with cognitive decline after 3 years). Dementia screening 6 years after scanning resulted in nine AD cases from the cognitively stable (n=3) and cognitive decline group (n=6), who were assigned to a third group, the preclinical AD group. When regional differences in cortical volume in the parietal lobe areas were compared between groups, significant differences were found between either the cognitive decline or stable group on the one hand and preclinical AD individuals on the other hand in the inferior parietal lobule. Group membership was best predicted by the grey matter volume of the inferior parietal lobule, compared to the other parietal lobe areas. The parietal lobe was characterised by a differential atrophy pattern based on cognitive status, which is in agreement with the 'last-developed-first-atrophied' principle. Future studies should investigate the surplus value of the inferior parietal lobe as a potential marker for the diagnosis of AD compared to other brain regions, such as the medial temporal lobe and the prefrontal lobe. 相似文献
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