The categorization of thought disorder

We describe the development of a new system for categorizing thought disorder. In the development phase (Study 1), we examined the degree to which speech samples and definitions of thought disorder subtypes taken from: (1) the Scale for the Assessment of Thought, Language, and Communication (TLC); (2) the Though Disorder Index (TDI); and (3) the Assessment of Bizarre-Idiosyncratic Thinking (BIT), reflected disturbances in form versus disturbances in content. Ratings were provided by naive judges, experienced clinicians, and linguistic experts. The results contributed to the development of a new system dividing thought disorder into disturbances in (1) fluency, (2) discourse coherence, (3) content, and (4) social convention. In the validation phase (Study 2), 21 schizophrenic and 19 manic subjects were interviewed, interpreted proverbs, and responded to Rorschach cards. Subjects' speech was rated using the TLC, TDI, and BIT. We also measured hallucinations, delusions, and digit span performance. The results of Study 2 provided evidence supporting the validity of our new categorization system.     

Positive thought disorder in a hypothetically psychosis-prone population

Proverb interpretations of subjects who scored high on the Perceptual Aberration-Magical Ideation Scale (Chapman & Chapman, 1985) were compared with those of low-scoring controls. Responses to 10 familiar and 3 unfamiliar proverbs were scored for Bizarre-idiosyncratic thinking (Marengo, Harrow, Lanin-Kettering, & Wilson, 1986) and literalness (Hertler, Chapman, & Chapman, 1978). A Group by Type of Proverb (familiar versus unfamiliar) interaction was found for bizarre-idiosyncratic scores; (Per-Mags) scored higher than controls on unfamiliar, but not familiar proverbs. The Group X Familiarity interaction for bizarre-idiosyncratic scores indicates that the Per-Mag group displayed a subclinical, positive-thought disorder that is affected by the familiarity of the proverbs.     

Building therapeutic relationship in schizophrenic and alcohol-related disorder cases

Current literature on the dual diagnosis in cases of schizophrenia and alcohol dependence has reported how pharmacological treatment has positive effects on the reduction of both disorders. Nevertheless, patients have considerable difficulties in following the prescribed medication. This work aims to build an engagement stage and therapeutic relationship in seven patients with schizophrenic and alcohol-related disorder cases. This result was achieved through the use of the vignette technique and narrative psychodynamic approach during group counselling sessions. Positive and Negative Symptoms Scale (PANSS) and Munich Alcoholism Test (MALT) were applied before and after treatment. A follow-up session was organized. The PANSS and MALT scores indicated there was no reduction of the psychiatric symptoms after treatment. The follow-up session showed positive outcomes in terms of increasing the level of socialisation as well as awareness of their own condition; at the same, an adherence to pharmacological treatment and psychotherapy for all the subjects.     

Thought-action fusion and thought suppression in obsessive-compulsive disorder.

To examine the significance of thought-action fusion (TAF) and thought suppression tendencies, the present study obtained pre- and post-treatment questionnaire data on these constructs in a sample of OCD patients (n=24) and non-OCD anxiety patients (n=20). Results indicate that TAF and suppression are correlated with severity of psychopathology. Yet, the associations between TAF and psychopathology are not typical for OCD, but do also occur in other anxiety disorders (e.g., panic disorder, post traumatic stress disorder, and social phobia). As well, mean scores on the TAF and thought suppression measures dropped significantly from pre- to post-treatment, indicating that TAF and thought suppression are susceptible to change during psychotherapy.     

时序知觉影响因素与思考

时序知觉是在几十毫秒到几百毫秒内, 对事件的同时性、非同时性和顺序性的知觉。对时序知觉的影响因素的探索可分为自下而上和自上而下两种研究取向。自下而上的研究探讨刺激的物理特征、被试的生物学特征, 以及实验方法对时序知觉的影响。而自上而下的研究探讨因果信念、情绪、文化对时序知觉的影响。今后的研究还应结合行为实验与神经科学技术, 深入探讨时序知觉的两种加工方式是分离的还是同时进行的, 以及揭示控制时序加工的脑区。     

Boyhood separation anxiety disorder: thought disorder and object relations psychopathology as manifested in Rorschach imagery

Rorschach scales were used to examine the quality of thought disturbance and object relations in boys meeting the Diagnostic and Statistical Manual of Mental Disorders, third edition (DSM-III; American Psychiatric Association, 1980) criteria for separation anxiety disorder (SAD). Nineteen urban, middle and low socioeconomic status (SES), SAD boys were compared to a group of 14 male control subjects. The hypotheses of the study were that SAD boys as compared to controls would: (a) have significantly more thought disordered responses as measured by a Rorschach Thought Disorder Scale (Blatt & Ritzler, 1974), and (b) evidence significantly less adaptive object relations scale scores as measured by the Mutuality of Autonomy Scale (Urist, 1977). Results confirmed both hypotheses. The SAD group had more thought disordered responses and more disrupted object relations scores than the controls. Ideas and images of these boys were found to generally be more unstable, boundary compromised, fluid, idiosyncratic, tangential, and psychotic-like than the controls. It was concluded that these boys possess a significant potential to have thinking abnormalities that will interfere with their independent functioning. Concerning their object relations scores, the SAD subjects were found to have significantly fewer benign, adaptive object interactional percepts, and a greater number of dependent and/or clinging interactional object representations (imagery) than the controls. This study supports the viewpoint that SAD boys are deeply psychologically troubled.     

Cognitive impairments associated with formal thought disorder in people with schizophrenia

Formal thought disorder (FTD), or disorganized speech, is one of the central signs of schizophrenia. Despite extensive research, the cognitive processes associated with FTD are still unclear. However, the authors' review of FTD theories and research indicates that considerable progress has been made in identifying possible cognitive impairments associated with FTD. Specifically, FTD is strongly associated with impaired executive functioning and with impaired processing of semantic information. Their review indicates that previous research has not yet supported an association between FTD and either an increase in spreading activation or an impairment within the language production system.     

Stability of formal thought disorder and referential communication disturbances in schizophrenia

This study examined the degree to which different types of communication disturbances in the speech of 48 schizophrenia patients and 28 controls were variable and state related versus stable and traitlike. Clinically rated formal thought disorder and 5 types of referential disturbance showed substantial stability within participants over time. The sixth type of referential disturbance, the vague reference, was not stable over time. Formal thought disorder was associated with the severity of core psychotic symptoms in patients. whereas referential disturbances showed little or no association with positive or negative symptom severity. Furthermore, changes in psychotic symptoms over time were accompanied by corresponding changes in formal thought disorder but not referential disturbances. These results support the idea that some types of referential disturbances are traitlike and may be reflective of vulnerability as well as manifest illness.     

The effects of haloperidol on thought disorder and IQ in schizophrenia

The impact of haloperidol treatment on the Wechsler Adult Intelligence Scale (WAIS) and the Thought Disorder Index was investigated in a group of 19 patients with schizophrenia tested both before and after 26 days of treatment with haloperidol. Thought disorder scores declined significantly over the course of treatment and fewer patients demonstrated severe forms of thought disorder at the end of the trial. WAIS performance improved significantly but the magnitude of change was consistent with the literature on expected practice effects. Thought disorder scores were negatively correlated with IQ at baseline, but not at Day 26. The results suggest a partial dissociation of thought disorder and other cognitive functions in schizophrenia.     

Finding MAPs using strongly equivalent high order recurrent symmetric connectionist networks

Belief revision is the problem of finding the most plausible explanation for an observed set of evidences. It has many applications in various scientific domains like natural language understanding, medical diagnosis and computational biology. Bayesian Networks (BN) is an important probabilistic graphical formalism widely used for belief revision tasks. In BN, belief revision can be achieved by finding the maximum a posteriori (MAP) assignment. Finding MAP is an NP-Hard problem. In previous work, we showed how to find the MAP assignment in BN using High Order Recurrent Neural Networks (HORN) through an intermediate representation of Cost-Based Abduction. This method eliminates the need to explicitly construct the energy function in two steps, objective and constraints. This paper builds on that previous work by providing the theoretical foundation and proving that the resultant HORN used to find MAP is strongly equivalent to the original BN it tries to solve.     

Interrater reliability and coding guide for nonpsychotic formal thought disorder

Reliable and valid assessment of abnormal speech patterns may enable earlier recognition of nonpsychotic disorders through characteristic speech patterns. This study sought to establish interrater reliability using a standardized guide for scoring. A scoring guide defining 27 elements (e.g., inappropriate self-reference, simple loss of goal, circumstantiality) of disordered thought was developed. The seminal work of Andreasen's and Holzman's groups provided 12 elements, and 15 new elements were suggested by clinical literature. Audiotaped interviews with 12 psychiatric inpatients, adults of both sexes and various ages hospitalized for acute management of nonpsychotic psychiatric disorders, provided speech samples for observation of disordered thought by two independent raters. Using the guide's definitions and accompanying examples of elements of disordered thought, reliability in scoring was high (kappa of .85 for agreement on the presence of any abnormal speech element and kappa values from .66 to 1.00 for agreement on the presence of individual elements).