Working memory retrieval differences between medial temporal lobe epilepsy patients and controls: A three memory layer approach

Multi-store models of working memory (WM) have given way to more dynamic approaches that conceive WM as an activated subset of long-term memory (LTM). The resulting framework considers that memory representations are governed by a hierarchy of accessibility. The activated part of LTM holds representations in a heightened state of activation, some of which can reach a state of immediate accessibility according to task demands. Recent neuroimaging studies have studied the neural basis of retrieval information with different states of accessibility. It was found that the medial temporal lobe (MTL) was involved in retrieving information within immediate access store and outside this privileged zone. In the current study we further explored the contribution of MTL to WM retrieval by analyzing the consequences of MTL damage to this process considering the state of accessibility of memory representations. The performance of a group of epilepsy patients with left hippocampal sclerosis in a 12-item recognition task was compared with that of a healthy control group. We adopted an embedded model of WM that distinguishes three components: the activated LTM, the region of direct access, and a single-item focus of attention. Groups did not differ when retrieving information from single-item focus, but patients were less accurate retrieving information outside focal attention, either items from LTM or items expected to be in the WM range. Analyses focused on items held in the direct access buffer showed that consequences of MTL damage were modulated by the level of accessibility of memory representations, producing a reduced capacity.     

SKOOL versus ZOOL: effects of orthographic and phonological long-term memory on nonword immediate serial recall

In a now-classic study Besner and Davelaar (1982) reported an advantage of pseudohomophone (PSH) over nonword recall in a visual immediate serial recall (ISR) task, which remained under articulatory suppression (AS), and interpreted the findings as indicating PSH items obtain support from stored phonological long-term memory (LTM) representations even when phonological rehearsal is disrupted. However, one key question relating to this PSH effect remains: could the results have been contaminated by a potential confound of orthographic familiarity (i.e., PSH items often look like the word they sound like)? As a result, the present study examined the impact of orthography on PSH ISR. Our findings indicate that PSH accuracy was consistently higher for items that had an orthographic similarity to the parent word, and this effect did not interact with concurrent task. We therefore argue that PSH items in ISR obtain independent support from both orthographic and phonological LTM representations. The present study demonstrates the critical impact of orthographic LTM representations on visual nonword ISR, and we suggest that this may be a fruitful avenue for further research.     

Working memory and executive function: The influence of content and load on the control of attention

In a series of three experiments, increasing working memory (WM) load was demonstrated to reduce the executive control of attention, measured via task-switching and inhibitory control paradigms. Uniquely, our paradigms allowed comparison of the ability to exert executive control when the stimulus was either part of the currently rehearsed memory set or an unrelated distractor item. The results demonstrated a content-specific effect-insofar as switching attention away from, or exerting inhibitory control over, items currently held in WM was especially difficult-compounded by increasing WM load. This finding supports the attentional control theory that active maintenance of competing task goals is critical to executive function and WM capacity; however, it also suggests that the increased salience provided to the contents of WM through active rehearsal exerts a content-specific influence on attentional control. These findings are discussed in relation to cue-induced ruminations, where active rehearsal of evocative information (e.g., negative thoughts in depression or drug-related thoughts in addiction) in WM typically results from environmental cuing. The present study has demonstrated that when information currently maintained in WM is reencountered, it is harder to exert executive control over it. The difficulty with suppressing the processing of these stimuli presumably reinforces the maintenance of these items in WM, due to the greater level of attention they are afforded, and may help to explain how the cue-induced craving/rumination cycle is perpetuated.     

Why do we move our eyes while trying to remember? The relationship between non-visual gaze patterns and memory

Non-visual gaze patterns (NVGPs) involve saccades and fixations that spontaneously occur in cognitive activities that are not ostensibly visual. While reasons for their appearance remain obscure, convergent empirical evidence suggests that NVGPs change according to processing requirements of tasks. We examined NVPGs in tasks with long-term memory (LTM) and working memory (WM) requirements. Experiment 1 yielded significantly higher eye movement rate (EMR) in tasks requiring LTM search than in a WM task requiring maintenance of information. Experiment 2 manipulated accessibility of items in study-test episodic tasks using the levels of processing paradigm. EMR was high in episodic recall irrespective of item accessibility. Experiment 3 examined functional significance of saccades in LTM tasks. Voluntary saccadic suppression produced no evidence that saccades contribute to task performance. We discuss the apparent epiphenomenal nature of spontaneous saccades from an evolutionary perspective and outline a neuroanatomical model of the link between the saccadic and memory system.     

Examining the relationship between free recall and immediate serial recall: the effect of concurrent task performance

In 3 experiments, participants saw lists of 16 words for free recall with or without a 6-digit immediate serial recall (ISR) task after each word. Free recall was performed under standard visual silent and spoken-aloud conditions (Experiment 1), overt rehearsal conditions (Experiment 2), and fixed rehearsal conditions (Experiment 3). The authors found that in each experiment, there was no effect of ISR on the magnitude of the recency effect, but interleaved ISR disrupted free recall of those words that would otherwise be rehearsed. The authors conclude that ISR and recency cannot both be outputs from a unitary limited-capacity short-term memory store and discuss the possibility that the process of rehearsal may be common to both tasks.     

Maintenance of item and order information in verbal working memory

Although verbal recall of item and order information is well-researched in short-term memory paradigms, there is relatively little research concerning item and order recall from working memory. The following study examined whether manipulating the opportunity for attentional refreshing and articulatory rehearsal in a complex span task differently affected the recall of item- and order-specific information of the memoranda. Five experiments varied the opportunity for articulatory rehearsal and attentional refreshing in a complex span task, but the type of recall was manipulated between experiments (item and order, order only, and item only recall). The results showed that impairing attentional refreshing and articulatory rehearsal similarly affected recall regardless of whether the scoring procedure (Experiments 1 and 4) or recall requirements (Experiments 2, 3, and 5) reflected item- or order-specific recall. This implies that both mechanisms sustain the maintenance of item and order information, and suggests that the common cumulative functioning of these two mechanisms to maintain items could be at the root of order maintenance.     

Dissociating familiarity from recollection using rote rehearsal

Recollection-based recognition memory judgments benefit greatly from effortful elaborative encoding, whereas familiarity-based judgments are much less sensitive to such manipulations. In this study, we have examined whether rote rehearsal under divided attention might produce the opposite dissociation, benefiting familiarity more than recollection. Subjects rehearsed word pairs during the "distractor" phase of a working memory span task, and were then given a surprise memory test for the distractor items at the end of the experiment. Experiment 1 demonstrated that increasing rehearsal elevated the recognition rate for intact and rearranged pairs, but neither associative recognition accuracy nor implicit fragment completion benefited from rehearsal. The results suggest that rote rehearsal leads to a greater increase in familiarity than in recollection, and that the increase in observed familiarity cannot be attributed to effects of repetition priming. In Experiment 2, we tested item recognition with the remember/know procedure, and the results supported the conclusions of Experiment 1. Moreover, a signal detection model of remember/know performance systematically overpredicted rehearsal increases in remember rates, and this worsened when high-rehearsal items were assumed to be more variable in strength. The results suggest that rote rehearsal can dissociate familiarity from recollection at the time of encoding and that item recognition cannot be fully accommodated within a one-dimensional signal detection model.     

A processing approach to the working memory/long-term memory distinction: evidence from the levels-of-processing span task

Recent theories suggest that performance on working memory (WM) tasks involves retrieval from long-term memory (LTM). To examine whether WM and LTM tests have common principles, Craik and Tulving's (1975) levels-of-processing paradigm, which is known to affect LTM, was administered as a WM task: Participants made uppercase, rhyme, or category-membership judgments about words, and immediate recall of the words was required after every 3 or 8 processing judgments. In Experiment 1, immediate recall did not demonstrate a levels-of-processing effect, but a subsequent LTM test (delayed recognition) of the same words did show a benefit of deeper processing. Experiment 2 showed that surprise immediate recall of 8-item lists did demonstrate a levels-of-processing effect, however. A processing account of the conditions in which levels-of-processing effects are and are not found in WM tasks was advanced, suggesting that the extent to which levels-of-processing effects are similar between WM and LTM tests largely depends on the amount of disruption to active maintenance processes.     

The influence of acoustic and semantic similarity on long-term memory for word sequences

It has been shown that short-term memory (STM) for word sequences is grossly impaired when acoustically similar words are used, but is relatively unaffected by semantic similarity. This study tests the hypothesis that long-term memory (LTM) will be similarly affected. In Experiment I subjects attempted to learn one of four lists of 10 words. The lists comprised either acoustically or semantically similar words (A and C) or control words of equal frequency (B and D). Lists were learned for four trials, after which subjects spent 20 min. on a task involving immediate memory for digits. They were then asked to recall the word list. The acoustically similar list was learned relatively slowly, but unlike the other three lists showed no forgetting. Experiment II showed that this latter paradox can be explained by assuming the learning score to depend on both LTM and STM, whereas the subsequent retest depends only on LTM. Experiment III repeats Experiment I but attempts to minimize the effects of STM during learning by interposing a task to prevent rehearsal between the presentation and testing of the word sequences. Unlike STM, LTM proved to be impaired by semantic similarity but not by acoustic similarity. It is concluded that STM and LTM employ different coding systems.     

The relationship between memory performance and the number of rehearsals in free recall

The purpose of the present study was to examine the relationship between the number of rehearsals and long-term recall performance by means of an overt rehearsal procedure. Subjects were induced to concentrate their rehearsal activity on specific items in free recall tasks. In Experiment 1, both the primacy and the recency items that had received additional rehearsals were recalled with higher probability than were the ordinarily rehearsed items in immediate recall but not in final recall. Experiment 2 was designed to extend the occasions for subjects’ rehearsal by manipulating the rate of item presentation. The overall pattern of resulting data shewed that for neither recency items nor primacy items does the additional overt rehearsal reliably lead to facilitative effects on long-term recall performance. The possibility of a qualitative change in rehearsal is discussed.     

Conditions and consequences of maintenance rehearsal.

The present experiments investigated the idea that the anticipated delay to initial recall governs whether a subject will rely on elaborative or maintenance rehearsal. In agreement with earlier research, the results suggested that maintenance rehearsal is used only when words can be rehearsed up to the moment of recall. A novel finding concerned the accessibility of the items processed in that way. When subjects were explicitly asked to recall those items first in final free recall, they were as likely to be recalled as items that had been processed elaboratively. This finding suggests that even rote rehearsal creates an accessible memory trace, albeit one that is most efficiently accessed by contextual rather than semantic cues.     

Characteristics of spatial memory span: Is there an analogy to the word length effect, based on movement time?

In studies of verbal short-term memory it has been shown that the length of words to be remembered affects the size of memory span. This word-length effect is attributed to relationships between the rate of rehearsal of verbal material and the time it takes to speak the words being rehearsed. For spatial memory span there may also be an internal rehearsal system linked to overt responding, and if there is a strong analogy to be drawn between the verbal and spatial domains then movement time between spatial targets should predict the number of spatial locations that can be recalled. In the experiments reported here the time taken to move between spatial targets is varied by altering the size of targets and the distance between them. No difference between span performance on a nine-block spatial span task were found, either on immediate recall or on recall after an interval. When recall is of items from an array of 27, grouped in nine sets of three, with only one location in any set being presented on any trial, there is an effect of display size. This effect is consonant with the argument that movement time is related to spatial rehearsal, but other explanations are also possible. However, if recall in this task is scored over the nine sets rather than over the 27 items, then there is no difference between the displays. The results indicate that performance on the normal nine-block spatial-span task cannot be predicted by movement time.     

A Dissociation Between Simple and Complex Span Impairment in Alcoholics

We investigated whether the surprisingly good memory performance of alcoholics may result from simple memory performance being spared while performance in complex memory tasks is impaired. Simple word span was contrasted with a complex word span task involving concurrent monitoring and re-organisation of items for recall. To control for disruption of rehearsal in the complex word span task, performance on two additional tasks with disrupted rehearsal but no additional processing components was studied. As hypothesised, the alcoholics showed a deficit in the complex but not the simple word span task. They were also impaired, compared to controls, on both tasks with disrupted rehearsal. The difference between groups remained in the complex span task when scores in simple span and either of the two other tasks were used as covariates. Thus, both executive processes necessary for coping with disrupted rehearsal and additional processes scheduling processing and storage in a complex task may play a role in accounting for working memory deficits found in alcoholics.     

Retrieval failure, rehearsal deficiency, and short-term memory loss in the aphasic adult

Studies show that aphasic patients typically are grossly impaired in short-term memory performance. Since aphasics generally experience difficulty in word retrieval, it is conceivable that short-term memory loss is partially the result of verbal rehearsal deficiency which, in turn, is caused by the word retrieval problem. This paper reports an experiment in which five aphasic adults were nonverbally to recall individualized lists of pictures they could easily name and lists of pictures they could not name. Final items in the two lists were recalled with equal accuracy; this was expected in that the recency effect usually reflects sensory rather than verbal storage. Initial items were recalled with greater accuracy than middle-list items in the nameable sets but not in the unnameable sets. This primacy effect suggests the aphasics rehearsed the nameable pictures, but both lists were recalled so poorly that rehearsal deficit was considered responsible for no more than a fraction of the aphasics' reduction in short-term memory.     

How verbal memory loads consume attention

According to a traditional assumption about working memory, participants retain a series of verbal items for immediate recall using covert verbal rehearsal, without much need for attention. We reassessed this assumption by imposing a speeded, nonverbal choice reaction time (CRT) task following the presentation of each digit in a list to be recalled. When the memory load surpassed a few items, performance on the speeded CRT task became increasingly impaired. This CRT task impairment depended only on attention-related components of working memory; it was not alleviated by the presence of an auditory memory trace that automatically helped the recall of items at the ends of spoken lists. We suggest that attention-demanding refreshing of verbal stimuli occurs along with any covert rehearsal.     

Thinking of critical words during study is unnecessary for false memory in the Deese,Roediger, and McDermott procedure

Do participants in the Deese, Roediger, and McDermott (DRM) procedure demonstrate false memory because they think of nonpresented critical words during study and confuse them with words that were actually presented? In two experiments, 160 participants studied eight visually presented DRM lists at a rate of 2 s or 5 s per word. Half of the participants rehearsed silently: the other half rehearsed overtly. Following study, the participants' memory for the lists was tested by recall or recognition. Typical false memory results were obtained for both memory measures. More important, two new results were observed. First, a large majority of the overt-rehearsal participants spontaneously rehearsed approximately half of the critical words during study. Second, critical-word rehearsal at study enhanced subsequent false recall, but it had no effect on false recognition or remember judgments for falsely recognized critical words. Thinking of critical words during study was unnecessary for producing false memory.     

Presentation format and its effect on working memory

In three experiments, we examined the separate cognitive demands of processing and storage in working memory and looked at how effective the coordination was when items for storage varied in format/modality. A sentence verification task involving arithmetic facts was combined with a span task involving two to six items presented in picture, printed word, or spoken word format. The first two experiments were the same, except for the added requirement of articulation of the math sentence in Experiment 2. Experiment 3 varied the length of the span item and compared recall with recognition performance. The results showed that both spoken words and picture produced superior recall and recognition, as compared with printed words, and are consistent with Baddeley and Logie's (1999) and Mayer's (2001) models of working memory. Also, the differences in processing performance across spans varied with the difficulty of the task but showed the strongest support for the resource allocation model (Foos 1995).     

Effects of talker variability on recall of spoken word lists

Three experiments were conducted to investigate recall of lists of words containing items spoken by either a single talker or by different talkers. In each experiment, recall of early list items was better for lists spoken by a single talker than for lists of the same words spoken by different talkers. The use of a memory preload procedure demonstrated that recall of visually presented preload digits was superior when the words in a subsequent list were spoken by a single talker than by different talkers. In addition, a retroactive interference task demonstrated that the effects of talker variability on the recall of early list items were not due to use of talker-specific acoustic cues in working memory at the time of recall. Taken together, the results suggest that word lists produced by different talkers require more processing resources in working memory than do lists produced by a single talker. The findings are discussed in terms of the role that active rehearsal plays in the transfer of spoken items into long-term memory and the factors that may affect the efficiency of rehearsal.     

Stimulus similarity decrements in children's working memory span

Two experiments investigated the impact of the relationship between processing and storage stimuli on the working memory span task performance of children aged 7 and 9 years of age. In Experiment 1, two types of span task were administered (sentence span and operation span), and participants were required to recall either the products of the processing task (sentence-final word, arithmetic total) or a word or digit unrelated to the processing task. Experiment 2 contrasted sentence span and operation span combined with storage of either words or digits, in tasks in which the item to be remembered was not a direct product of the processing task in either condition. In both experiments, memory span was significantly greater when the items to be recalled belonged to a different stimulus category from the material that was processed, so that in sentence span tasks, number recall was superior to word recall, and in operation span tasks, word recall was superior to number recall. Explanations of these findings in terms of similarity-based interference and response competition in working memory are discussed.     

Short-term memory in autism spectrum disorder

Three experiments examined verbal short-term memory in comparison and autism spectrum disorder (ASD) participants. Experiment 1 involved forward and backward digit recall. Experiment 2 used a standard immediate serial recall task where, contrary to the digit-span task, items (words) were not repeated from list to list. Hence, this task called more heavily on item memory. Experiment 3 tested short-term order memory with an order recognition test: Each word list was repeated with or without the position of 2 adjacent items swapped. The ASD group showed poorer performance in all 3 experiments. Experiments 1 and 2 showed that group differences were due to memory for the order of the items, not to memory for the items themselves. Confirming these findings, the results of Experiment 3 showed that the ASD group had more difficulty detecting a change in the temporal sequence of the items.