Sex task and processing strategy effects in hemispheric alpha asymmetries for the recall and recognition of arousal words: results from perceptual and motor tasks in males and females

Hemispheric alpha asymmetries of males and females were observed during perceptual and motor tasks requiring recall and recognition of words controlled for level of arousal (positive, negative, and neutral). Verbal reports of individual processing strategy were collected and analyzed relative to hemispheric alpha ratios. Results showed greater alpha suppression in the left relative to right hemisphere for recall as compared to recognition tasks and for word presentation when contrasted with motor conditions. High positive correlations were found between narrative report of processing strategy and hemispheric alpha data. A separate analysis revealed that seven subjects identified as highly analytic processors showed greater alpha suppression in the left relative to right hemisphere across tasks, conditions, and stimuli than did seven highly visual processors who, in contrast, demonstrated greater right hemispheric alpha suppression. Task difficulty and individual differences in processing style that modify cerebral laterality effects are discussed.     

The Effects of Procedural Variations on Lateralized Stroop Effects

Several issues in the classic Stroop effect remain open, including (i) the stage of processing which gives rise to the effect, (ii) the effect of some procedural manipulations, (iii) the effect of hemispheric specialization and of interhemispheric interactions, and (iv) the existence of individual differences. In this paper, we investigate these issues using a series of experiments with central, lateral, and bilateral presentations of the Stroop stimuli. A total of 146 right-handed subjects took part in a multiexperiment study with relatively equal numbers of the two sexes participating in each experiment. We found that manual responses diluted but did not abolish the Stroop interference relative to vocal responses, arguing for a late processing stage account of the effect. However, separating the color patch from the color word either unilaterally or bilaterally did not significantly change the magnitude of the Stroop interference, arguing against a cost of interhemispheric transfer in the Stroop effect in normal subjects. We did, however, find evidence for hemispheric specialization in Stroop interference, greater in the left hemisphere than in the right hemisphere. Color words in the RVF produced the greatest Stroop effects regardless of the location of the color patch. In most cases, this laterality effect interacted with the sex of the subject, such that only males and a subgroup of females (i.e., those tested during a low estrogen phase in the menstrual cycle) showed evidence for greater Stroop effects when a color word projected to the left hemisphere than when it projected to the right hemisphere, regardless of the placement of the color patch.     

Separate brain potential characteristics in children with reading disability and attention deficit disorder: color and letter relevance effects

This experiment was on event-related potential (ERP) indicants of the selective neural processing of black vs. white and letter vs. nonletter stimuli in boys (8-12 years of age) with and without a reading disability (RD) and/or attentional deficit disorder (ADD). Selective neural processing was measured by the increase or difference in ERP amplitude in response to stimuli that were relevant as compared to irrelevant to the color or letter attention task. The 52 children that participated in the study constituted four groups: 25 normal reading children (17 without ADD and 8 with ADD), and 27 RD children (11 without ADD and 16 with ADD). ERPs were recorded over the left and right occipital, central, and frontal regions. Selective neural processing due to stimulus relevance was reduced in boys with RD as compared to normal readers. This reduced selectivity was indicated by a predominantly symmetrical reduction in the magnitude of a positive difference potential over the central regions, between 300 and 360 msec, and then by a left greater than right hemisphere reduction in the magnitude of a positive difference potential over the occipital regions, at about 400 msec. Task relevance increased the within-subject and condition variability of this occipital positive component and this effect was greater for boys without than with RD, particularly over the left hemisphere. Selective neural processing due to stimulus relevance was greater in boys with ADD as compared to those without ADD. This was indicated by an increase in the magnitude of a positive difference potential between 320 and 400 msec over the central and frontal regions and a slow, late, negative difference potential between 600 and 800 msec over the central and occipital regions. These ADD effects tended to be greater over the right than left hemisphere. The unique polarity, scalp distribution, and time course of the effects of RD as compared to ADD on ERPs to relevant stimuli clearly indicated these two disorders, in part, involve different underlying brain deficits.     

Hemispheric differences in picture-word interference

In a picture-word version of the Stroop task, 30 right-handed subjects were tested under each of six conditions in which a picture alone or a picture plus a word were presented to the left, the right, or both hemispheres. In two additional conditions the picture was presented to the right hemisphere and the word was simultaneously presented to the left hemisphere, or vice versa. For all conditions, subjects were instructed to name the picture only, as rapidly as possible. Picture naming times were significantly slower for the conditions in which the pictures were accompanied by words than in the respective picture alone conditions. Moreover, simultaneous presentation of a picture and a word to both hemispheres resulted in greater interference (slower picture naming times) than did the simultaneous presentation of the picture and the word to either the left hemisphere alone or the right hemisphere alone. The latter two conditions, in turn, resulted in significantly more interference than did the simultaneous presentation of the picture to one hemisphere and the word to the other hemisphere. This pattern of results suggests that the Stroop effect obtained under normal circumstances is in large part a function of the interference caused by the simultaneous processing of items in the same hemisphere. In contrast to hemispheric differences reported for the color-word Stroop task, the effect of presenting a picture and word simultaneously to the right hemisphere did not differ reliably from that of presenting a picture and word to the left hemisphere. The failure to replicate this aspect of the color-word Stroop is attributed to differences in the abilities of the two hemispheres to process the respective target items (the color or the picture) of the two tasks.     

Lateralization of lexical codes in auditory word recognition

Three experiments examined the lateralization of lexical codes in auditory word recognition. In Experiment 1 a word rhyming with a binaurally presented cue word was detected faster when the cue and target were spelled similarly than when they were spelled differently. This orthography effect was larger when the target was presented to the right ear than when it was presented to the left ear. Experiment 2 replicated the interaction between ear of presentation and orthography effect when the cue and target were spoken in different voices. In Experiment 3, subjects made lexical decisions to pairs of stimuli presented to the left or the right ear. Lexical decision times and the amount of facilitation which obtained when the target stimuli were semantically related words did not differ as a function of ear of presentation. The results suggest that the semantic, phonological, and orthographic codes for a word are represented in each hemisphere; however, orthographic and phonological representations are integrated only in the left hemisphere.     

Hemispace and information control by the two cerebral hemispheres: which interaction?

Two experiments employing subjects with different experience in tactile discrimination (blind and seeing subjects) were carried out to investigate the effect of the space location of stimuli on the information processing activity of the two cerebral hemispheres. An angle discrimination task that yields a right hemisphere superiority was used. In Experiment 1, seeing subjects showed a general superiority of the left hand (right hemisphere) which was more pronounced in the left hemispace with respect to the central and the right hemispace performance. In Experiment 2, blind subjects showed a significant superiority of the left hand in the central and in the left hemispace and no difference between the two hands in the right hemispace. In both experiments hemispace differences were due only to the modification of the left hand (right hemisphere) performance. These results suggest that the hemispace control by the contralateral hemisphere interacts only with the activity of the hemisphere dominant in the information processing.     

Hemispheric asymmetry and electrodermal activity in orienting and pavlovian conditioning paradigms

Three experiments on lateralization of electrodermal orienting and conditioned behavior are reported. The basic findings show effects of hemispheric asymmetry on initial magnitude and rate of habituation of phasic stimulus-elicited electrodermal responses. In summary, responses to verbal stimuli repeatedly flashed to the right visual half-field are larger than corresponding responses in the left half-field. Similarily, spatially relevant stimuli initially presented to the left half-field result in larger responses than when the same stimuli are repeatedly presented in the right half-field. In the auditory modality, data show asymmetrical control of responding to verbal material in a dichotic conditioning paradigm with greater resistance to extinction when the conditioned stimulus is initially fed only to the left hemisphere as compared to when it is fed only to the right hemisphere. It is argued that the present approach taps on basic mechanisms for the lateralization of attentional and associative functions.     

Form-specific visual priming in the right cerebral hemisphere.

Results of 4 experiments indicate that both within-modality and case-specific visual priming for words are greater when test stimuli are presented initially to the right cerebral hemisphere (RH). In contrast, neither within-modality nor case-specific explicit memory for words is greater when stimuli are presented initially to the RH. Priming is measured using word-stem completion, and explicit memory is measured using word-stem cued recall. In both cases, Ss first rate how much they like words, and then word stems are presented briefly to the RH (in the left visual field) or to the left hemisphere (in the right visual field). Results suggest that at least 2 separate systems encode the visual representations that produce priming. The system that is more effective in the RH is better at representing form-specific information, whereas another system that is not more effective in the RH does not distinguish among distinct instances of word forms.     

A Search for the Optimal Stimulus

How do stimulus size and item number relate to the magnitude and direction of error on center estimation and line cancellation tests? How might this relationship inform theories concerning spatial neglect? These questions were addressed by testing twenty patients with right hemisphere lesions, eleven with left hemisphere lesions and eleven normal control subjects on multiple versions of center estimation and line cancellation tests. Patients who made large errors on these tests also demonstrated an optimal or pivotal stimulus value, i.e., a particular size center estimation test or number of lines on cancellation that either minimized error magnitude relative to other size stimuli (optimal) or marked the boundary between normal and abnormal performance (pivotal). Patients with right hemisphere lesions made increasingly greater errors on the center estimation test as stimuli were both larger and smaller than the optimal value, whereas those with left hemisphere lesions made greater errors as stimuli were smaller than a pivotal value. In normal subjects, the direction of errors on center estimation stimuli shifted from the right of true center to the left as stimuli decreased in size (i.e., the crossover effect). Right hemisphere lesions exaggerated this effect, whereas left hemisphere lesions diminished and possibly reversed the direction of crossover. Error direction did not change as a function of stimulus value on cancellation tests. The demonstration of optimal and pivotal stimulus values indicates that performances on center estimation and cancellation tests in neglect are only relative to the stimuli used. In light of other studies, our findings indicate that patients with spatial neglect grossly overestimate the size of small stimuli and underestimate the size of large stimuli, that crossover represents an “apparent” shift in error direction that actually results from normally occurring errors in size perception, and that the left hemisphere is specialized for one aspect of size estimation, whereas the right performs dual roles.     

Cognitive consequences of individual differences in arousal asymmetry

Prior research has demonstrated that semantic organization in the right hemisphere (RH) is more diffuse and specialized for distant semantic associates than is semantic organization in the left hemisphere (LH). The present research explored individual differences in this regard. If the RH is more specialized for distant semantic associates, then individuals with a more active RH should display greater activation of distant semantic associations. Two experiments were conducted to examine this issue. In both studies a line bisection task was used to assess arousal asymmetry. In Experiment 1, greater RH activation was associated with the ability to generate remote associates to three word stimuli. In Experiment 2, relatively greater RH activation was associated with enhanced priming of distant semantic associates. Taken together, these experiments demonstrate that arousal asymmetry is an individual difference variable that is related to variability in semantic organization and retrieval.     

Hemispheric differences in the time-course of semantic priming processes: evidence from event-related potentials (ERPs)

To investigate hemispheric differences in the timing of word priming, the modulation of event-related potentials by semantic word relationships was examined in each cerebral hemisphere. Primes and targets, either categorically (silk-wool) or associatively (needle-sewing) related, were presented to the left or right visual field in a go/no-go lexical decision task. The results revealed significant reaction-time and physiological differences in both visual fields only for associatively related word pairs, but an electrophysiological difference also tended to reach significance for categorically related words when presented in the left visual field. ERP waveforms showed a different time-course of associative priming effects according to the field of presentation. In the right visual field/left hemisphere, both N400 and Late Positive Component (LPC/P600) were modulated by semantic relatedness, while only a late effect was present in the left visual field/ right hemisphere.     

Developmental dyslexia: Electrophysiological evidence of clinical subgroups

Event-related potentials (ERPs) to word and to musical-chord stimuli were recorded in 13 dyslexic boys and 13 age-matched normal readers. Normal readers and dyslexics whose reading handicaps involved visual-spatial processing deficits had greater word versus musical-chord ERP waveform differences over the left as compared to the right hemisphere. Dyslexics whose reading difficulties were related to auditory-verbal processing deficits did not exhibit this asymmetry. These results are interpreted as supportive of the hypothesis that the latter group of dyslexics has failed to develop normal left hemisphere specialization for processing of auditory-linguistic material.     

Emotional Television Scenes and Hemispheric Specialization

This study examined hemispheric differences¹ in cortical arousal as a function of positive and negative emotional television scenes. A three-factor within-subjects design was used: hemispheres (right and left), location of cortical arousal (frontal and occipital), and emotional content of messages (positive and negative). Based on findings that the frontal cortex responds differently to emotional stimuli, it was predicted that negative television content would produce greater right hemisphere activity, and that positive content would produce greater left hemisphere activity, but that differences would be apparent only in the frontal region. The results confirmed these predictions. There was a significant interaction between hemisphere and emotional content for frontal alpha, but no interaction for occipital alpha.² There were two other main effects: (1) greater cortical arousal for negative than positive scenes, and (2) greater occipital than frontal arousal. The results are discussed in relation to a definition of emotional scenes that emphasizes approach (positive emotion) versus withdrawal (negative emotion), and in relation to hemispheric specialization and the ability of television to prime overt behavior.     

Hemispheric alpha asymmetries of stuttering males and nonstuttering males and females for words of high and low imagery

Alpha hemispheric asymmetries of nonstuttering males, nonstuttering females, and stuttering males were explored with electroencephalographic procedures during exposure to two lists of one-syllable words which the subjects were required to recall following presentation. One word list contained low-imagery words while the other contained high-imagery words. Stuttering males were found to have significantly less alpha in their right hemispheres, suggesting right hemispheric processing strategies. This finding was interpreted as supporting the “segmentation dysfunction” explanation of stuttering suggested by Moore and Haynes (1979b). Nonstuttering males showed less left than right alpha while nonstuttering females revealed no difference between their right and left hemispheres. Differences between nonstuttering males and females are discussed as being task and stimuli dependent relative to the segmental/nonsegmental nature of both task and stimuli. Differential hemispheric asymmetries for words of high or low-imagery were not observed.     

Motivation, affect, and hemispheric asymmetry: power versus affiliation

In 4 experiments, the authors examined to what extent information related to different social needs (i.e., power vs. affiliation) is associated with hemispheric laterality. Response latencies to a lateralized dot-probe task following lateralized pictures or verbal labels that were associated with positive or negative episodes related to power, affiliation, or achievement revealed clear-cut laterality effects. These effects were a function of need content rather than of valence: Power-related stimuli were associated with right visual field (left hemisphere) superiority, whereas affiliation-related stimuli were associated with left visual field (right hemisphere) superiority. Additional results demonstrated that in contrast to power, affiliation primes were associated with better discrimination between coherent word triads (e.g., goat, pass, and green, all related to mountain) and noncoherent triads, a remote associate task known to activate areas of the right hemisphere.     

Hemispheric differences in case processing

Morphosyntactic capacities of normal brain hemispheres were compared in lexical decision studies involving centrally and laterally presented Serbo-Croatian nouns in different cases. Cases are distinguished by different suffixes and syntactic roles. Experiment 1 confirmed and extended previous findings of the nominative superiority effect: words in the nominative case were processed faster and more accurately than words in other three cases, and nonwords in the nominative case led to more false positive reactions than nonwords in other cases. In Experiment 2 this effect was replicated for right visual field stimuli: nominatives had faster reaction times and smaller error rates than accusatives, and the reversed pattern was found for nonwords. For left visual field stimuli, only the word error analysis found the nominative superior, while the other three analyses (word reaction times, nonword reaction times, and nonword error rates) showed no significant case effect. Word familiarity had an equally strong effect in both hemispheres. The results suggest that centrally presented stimuli are processed by the left hemisphere, that laterally presented stimuli are processed by the initially receiving hemisphere, and that the right hemisphere has a frequency-sensitive lexicon. Reduced right-hemisphere sensitivity for case differences may be due to different lexicon structure or the absence of appropriate morphological or syntactic mechanisms.     

Evidence for dissociable neural mechanisms underlying inference generation in familiar and less-familiar scenarios

In this study, we investigated whether the left and right hemispheres are differentially involved in causal inference generation. Participants read short inference-promoting texts that described either familiar or less-familiar scenarios. After each text, they performed a lexical decision on a letter string (which sometimes constituted an inference-related word) presented directly to the left or right hemisphere. Response-time results indicated that hemisphere of direct presentation interacted with type of inference scenario. When test stimuli were presented directly to the left hemisphere, lexical decisions were facilitated following familiar but not following less-familiar inference scenarios, whereas when test stimuli were presented directly to the right hemisphere, facilitation was observed in both familiar and less-familiar conditions. Thus, inferences may be generated in different ways depending on which of two dissociable neural subsystems underlies the activation of background information.     

Hemispheric differences in processing handwritten cursive

Hemispheric asymmetry was examined for native English speakers identifying consonant-vowel-consonant (CVC) non-words presented in standard printed form, in standard handwritten cursive form or in handwritten cursive with the letters separated by small gaps. For all three conditions, fewer errors occurred when stimuli were presented to the right visual field/left hemisphere (RVF/LH) than to the left visual field/right hemisphere (LVF/RH) and qualitative error patterns indicated that the last letter was missed more often than the first letter on LVF/RH trials but not on RVF/LH trials. Despite this overall similarity, the RVF/LH advantage was smaller for both types of cursive stimuli than for printed stimuli. In addition, the difference between first-letter and last-letter errors was smaller for handwritten cursive than for printed text, especially on LVF/RH trials. These results suggest a greater contribution of the right hemisphere to the identification of handwritten cursive, which is likely related visual complexity and to qualitative differences in the processing of cursive versus print.     

Evidence for dissociable neural mechanisms underlying inference generation in familiar and less-familiar scenarios

In this study, we investigated whether the left and right hemispheres are differentially involved in causal inference generation. Participants read short inference-promoting texts that described either familiar or less-familiar scenarios. After each text, they performed a lexical decision on a letter string (which sometimes constituted an inference-related word) presented directly to the left or right hemisphere. Response-time results indicated that hemisphere of direct presentation interacted with type of inference scenario. When test stimuli were presented directly to the left hemisphere, lexical decisions were facilitated following familiar but not following less-familiar inference scenarios, whereas when test stimuli were presented directly to the right hemisphere, facilitation was observed in both familiar and less-familiar conditions. Thus, inferences may be generated in different ways depending on which of two dissociable neural subsystems underlies the activation of background information.     

The effect of word length on hemispheric word recognition: evidence from unilateral and bilateral-redundant presentations

Visual half field studies have repeatedly demonstrated the left hemisphere's superiority for language processing. Previous studies examined the effect of word length on bilateral and unilateral performance by comparing foveal and parafoveal presentations. The present study removed the potential confound of acuity by using parafoveal presentations for both unilateral and bilateral trials. Twenty participants named 3-, 4-, 5-, and 6-letter words. The results supported previous findings, with right hemisphere performance being particularly degraded with increases in word length. There was no difference between left hemisphere and bihemispheric performance in terms of speed or accuracy, suggesting that bihemispheric performance is reliant upon the strategy of the hemisphere superior for language processing. Overall, the pattern of results supports the notion that the left hemisphere's superior linguistic capacity results from a more parallel processing strategy, while the right hemisphere is reliant upon a more sequential mechanism.