Inhibiting reactions to emotional versus non‐emotional response cues in schizophrenia: Insights from a motor‐process paradigm

Recent models of schizophrenia suggest deficient use of contextual response cues when confronted with countermanding emotional cues. It is important to clinically validate these models by testing patients diagnosed with schizophrenia on tasks with competing emotional and contextual response determinants. Control and schizophrenia groups completed a novel task that elicited motor responses consistent with, or in opposition to, pre‐potent emotional actions (i.e., approach vs. avoidance). An analogous non‐emotional task was also used to examine cue‐conflict impairment more generally. The groups demonstrated statistically equivalent performance decrements on incongruent versus congruent trials on both tasks. However, within the schizophrenia group, the incongruency effect was significantly greater in the emotional versus non‐emotional task. These data suggest that, while patients with schizophrenia were able to employ contextual response cues to override competing emotional responses, they were slower to resolve emotional versus non‐emotional response conflict. When patients were subdivided according to the presence or absence of disorganized symptoms, this effect was confined to patients with disorganized symptoms.     

职前教师情绪觉察能力对情绪信息注意偏向的影响

采用修订的情绪觉察水平量表（LEAS）对315名职前教师进行调查,并从中筛选出高、低情绪觉察能力组被试各60人,分别完成情绪面孔Stroop任务（研究1）和情绪词Stroop任务（研究2）。（1）研究1的正确率上,中性面孔最高,愉快面孔次之,悲伤面孔最差;反应时上,悲伤面孔最长,愉快面孔次之,中性面孔最短;高分组仅在愉快和中性面孔上的反应时长于低分组;消极面孔的干扰效应高于积极面孔的干扰效应。（2）研究2的反应时上,消极词的反应时最长,显著长于中性和积极词;高分组仅在积极词和中性词上的反应时长于低分组,且高分组在积极词上的干扰效应高于低分组。研究结果表明与中性刺激相比,高低情绪觉察能力组均对情绪刺激产生了注意偏向,尤其是负性情绪刺激;与低情绪觉察能力组相比,高情绪觉察能力职前教师不仅对消极情绪信息产生注意偏向,还对积极情绪信息产生注意偏向。     

Emotional Stroop task: effect of word arousal and subject anxiety on emotional interference

Inconsistent findings regarding the emotional Stroop effect in healthy subjects may be explained by confounding effects of stimulus valence and arousal, as well as individual differences in anxiety. We examined reaction time data in a healthy sample using the emotional Stroop task while carefully matching arousal level of positive and negative words. Independent of valence, emotional relative to neutral words elicited emotional interference, indicating that arousal determines emotional interference. Independent of valence, emotional words were better re-called and recognized than neutral words. Individual differences in state anxiety were associated with emotional interference, that is, emotional interference was enhanced in subjects with high state anxiety. There was no influence of trait anxiety. These findings indicate that word arousal produces emotional interference independent of valence. State anxiety exacerbates interference of emotional words by further biasing attention towards emotionally salient stimuli. Thomas Dresler and Katja Mériau have contributed equally.     

负性情境诱导下抑郁个体的情绪Stroop效应：ERPs研究

运用ERPs技术探讨了正常和抑郁个体在中性和负性情境诱导下的情绪Stroop效应。结果发现正常被试在负性情境下对中性词判断的错误率比在中性情境下更高,对负性词加工的P1波幅减小、N1增大,出现了Stroop效应;抑郁被试在两种情境下对负性词加工的P1和 N1波幅没有差异。研究结果提示,抑郁个体在负性情境下出现注意脱离困难和资源不足,难以解决情绪冲突任务,支持了注意脱离损伤假说,并进一步说明抑郁个体的情绪选择性注意加工会受到心境一致性状态的影响,因过多的注意资源卷入从而出现负性情绪调节不良。实验结果为探讨抑郁个体对负性情绪的注意加工和调节过程提供了来自电生理的证据。     

Neurophysiological evidence for disturbances of conflict processing in patients with schizophrenia

Deficits in cognition are a hallmark of schizophrenia. In the present study, the authors investigated the effects of schizophrenia on the neural correlates of conflict processing in a single-trial version of the Stroop task by using event-related brain potentials. Relative to matched controls, patients with schizophrenia showed increased Stroop interference in response time, but this effect was eliminated when the effect of response slowing was controlled. In controls, conflict processing was associated with a negative wave peaking between 400 and 500 ms (N450) and conflict sustained potential (SP) peaking between 600 and 800 ms after stimulus onset. In patients with schizophrenia, the amplitude of the N450 was significantly attenuated and the conflict SP was absent. These results provide evidence for the existence of altered neural processes associated with conflict processing that may be associated with dysfunction of the anterior cingulate and prefrontal cortex in patients with schizophrenia.     

What is the nature of increased Stroop interference in schizophrenia?

In comparison to controls, patients with schizophrenia classically display (1) an overall slowing in response times (RTs) and (2) a disproportionate slowing in RTs in the conflict condition of the Stroop color/word interference task. These two effects appear repeatedly in the card version of the Stroop task but were not replicated in a number of studies using a computer item-by-item version of the task. The present study was aimed at understanding the exact nature of the increased interference classically found in the performance of patients with schizophrenia in the card version of the Stroop task. We used a computer trial-by-trial version in which we investigated the effects of two major methodological differences between the two versions: (1) blocked (card version) versus mixed (computer version) presentation of the neutral, congruent and conflict conditions and (2) presence (card version) versus absence (computer version) of distractors in the spatial surrounding of the target. We found an overall slowing in performance and a disproportionate slowing in the conflict condition for patients with schizophrenia but only when the target was surrounded by distractors (in Experiments 2 and 3). The data are discussed in terms of a deficit in selective attention and inhibitory processes in schizophrenia.     

Narrating emotional events in schizophrenia

Research has indicated that schizophrenia patients report similar amounts of experienced emotion in response to emotional material compared with nonpatients. However, less is known about how schizophrenia patients describe and make sense of their emotional life events. We adopted a narrative approach to investigate schizophrenia patients' renderings of their emotional life experiences. In Study 1, patients' (n=42) positive and negative narratives were similarly personal, tellable, engaged, and appropriate. However, negative narratives were less grammatically clear than positive narratives, and positive narratives were more likely to involve other people than negative narratives. In Study 2, emotional (positive and negative) narratives were less tellable and detached, yet more linear and social compared with neutral narratives for both schizophrenia patients (n=24) and healthy controls (n=19). However, patients' narratives about emotional life events were less appropriate to context and less linear, and patients' narratives, whether emotional or not, were less tellable and more detached compared with controls' narratives. Although schizophrenia patients are capable of recounting life events that trigger different emotions, the telling of these life events is fraught with difficulty.     

Understanding anhedonia in schizophrenia through lexical analysis of natural speech

Anhedonia is a negative prognostic indicator in schizophrenia. However, the underlying nature of this emotional deficit is unclear. Laboratory studies examining patients’ emotional reactions under controlled circumstances have failed to find evidence for a diminished hedonic response, instead finding that patients’ reactions to laboratory stimuli are characterised by high levels of negative emotion. The present study employed lexical analysis of natural speech in 52 patients and 49 non-patient controls while they discussed separate neutral, pleasant and unpleasant autobiographical memories. Patients with clinically rated anhedonia, versus other patients and controls, showed a dramatic increase in negative emotion expression when discussing pleasurable memories, but they showed no corresponding decrease in positive emotion. These findings provide further evidence that “anhedonia” is more reflective of negative emotional states than the absence of positive ones. These findings also raise questions about how positive and negative emotions can be simultaneously co-activated in patients with schizophrenia.     

情绪Stroop效应：威胁驱动还是反应偏差？

为了考查情绪Stroop效应的产生机制是威胁驱动还是反应偏差,本研究进行了两个实验.实验一用一般负性情绪词语和中性词语作为实验材料,实验二用威胁性的情绪图片和中性图片作为实验材料.每个实验均要求一组被试做按键反应,另一组被试做摇杆反应.结果发现,当实验材料为词语时,未出现情绪Stroop效应;当实验材料为威胁性图片时,无论是趋向性反应方式还是回避性反应方式,都出现了情绪Stroop效应.本研究结果支持威胁驱动机制.     

Event‐related oscillations (EROs) and event‐related potentials (ERPs) comparison in facial expression recognition

The study aims to explore the significance of event‐related potentials (ERPs) and event‐related brain oscillations (EROs) (delta, theta, alpha, beta, gamma power) in response to emotional (fear, happiness, sadness) when compared with neutral faces during 180–250 post‐stimulus time interval. The ERP results demonstrated that the emotional face elicited a negative peak at approximately 230 ms (N2). Moreover, EEG measures showed that motivational significance of face (emotional vs. neutral) could modulate the amplitude of EROs, but only for some frequency bands (i.e. theta and gamma bands). In a second phase, we considered the resemblance of the two EEG measures by a regression analysis. It revealed that theta and gamma oscillations mainly effect as oscillation activity at the N2 latency. Finally, a posterior increased power of theta was found for emotional faces.     

Intact emotion–cognition interaction in schizophrenia patients and first-degree relatives: Evidence from an emotional antisaccade task

Schizophrenia patients have deficits in cognitive control as well as in a number of emotional domains. The antisaccade task is a measure of cognitive control that requires the inhibition of a reflex-like eye movement to a peripheral stimulus. Antisaccade performance has been shown to be modulated by the emotional content of the peripheral stimuli, with emotional stimuli leading to higher error rates than neutral stimuli, reflecting an implicit emotion processing effect. The aim of the present study was to investigate the impact on antisaccade performance of threat-related emotional facial stimuli in schizophrenia patients, first-degree relatives of schizophrenia patients and healthy controls. Fifteen patients, 22 relatives and 26 controls, matched for gender, age and verbal intelligence, carried out an antisaccade task with pictures of faces displaying disgusted, fearful and neutral expressions as peripheral stimuli. We observed higher antisaccade error rates in schizophrenia patients compared to first-degree relatives and controls. Relatives and controls did not differ significantly from each other. Antisaccade error rate was influenced by the emotional nature of the stimuli: participants had higher antisaccade error rates in response to fearful faces compared to neutral and disgusted faces. As this emotional influence on cognitive control did not differ between groups we conclude that implicit processing of emotional faces is intact in patients with schizophrenia and those at risk for the illness.     

内隐/外显不同水平攻击者的注意偏向：行为和ERP证据

通过行为实验（点探测）和ERP实验（情绪Stroop）两个实验任务,考察了内隐/外显不同水平攻击者的注意偏向及其脑机制。结果表明：高外显攻击者对愤怒面孔存在注意偏向;高外显攻击者在愤怒面孔上的N100波幅显著低于中性面孔,表明其注意分配和调节能力较弱;高外显攻击者较之低外显攻击者的P300波幅更小表明其存在注意等方面的认知加工缺陷,N400波幅更小表明其对愤怒面孔进行语义编码时加工更为流畅;外显攻击组与内隐攻击组在FCz和Cz电极点上不同。这为内隐/外显攻击二者有着独立结构提供了行为与认知神经科学的证据。     

The dynamic influence of emotional words on sentence comprehension: An ERP study

In the present study, we explored the influence of emotional words on the semantic integration of their following neutral nouns during sentence comprehension. We manipulated the emotionality of verbs and the semantic congruity of their following (neutral) object nouns in sentences. Event-related potentials were recorded to the verbs, which were either negative or neutral, and to the object nouns, which were either semantically congruent or incongruent relative to the preceding contexts. We found an N400 and a P600 effect in response to the semantic congruity of the nouns when they followed the neutral verbs. However, the P600 (but not the N400) semantic congruity effect may have been attenuated when the nouns followed the negative verbs. Meanwhile, the negative verbs elicited a larger P2 and N400 than did the neutral verbs. The results indicate that the attention captured by emotional words impaired reanalysis of the following incongruent information, demonstrating a dynamic influence of emotional words on the semantic processing of following information during sentence comprehension.     

Independent manipulation of emotion in an emotional stroop task using classical conditioning

The effects of emotional connotation on emotional Stroop interference in anxiety were examined. First, a classical conditioning paradigm was used in which neutral words and nonwords were paired with either negative or neutral pictures. These conditioned stimuli were then presented in an emotional Stroop paradigm. Finally, participants rated each word and nonword for emotional connotation. The high-anxious group demonstrated significant interference for the nonwords that had been negatively conditioned, and these effects did not dissipate over time. The affective rating data supported the view that nonwords, but not the words had been successfully conditioned in the high-anxious group. This experiment provides evidence for the importance of emotional connotation rather than confounded semantic factors in the emotional Stroop effect.     

奖赏预期对面孔情绪加工的影响：一项事件相关电位研究

采用事件相关电位(ERPs)技术考察了奖赏预期对人类面孔情绪识别的影响。实验采用线索-目标范式, 分别记录了被试在奖赏预期条件下以及无奖赏预期条件下对正性、中性和负性面孔进行情绪辨别任务的ERP数据。行为结果显示, 被试在奖赏预期条件下的反应时快于无奖赏预期条件下的反应时, 对情绪面孔的反应时快于对中性面孔的反应时。ERPs数据显示, 奖赏线索比无奖赏线索诱发了更正的P1、P2和P300成分。目标刺激诱发的P1、N170波幅以及N300均受到奖赏预期的调节, 在奖赏预期条件下目标诱发了更正的ERPs。P1、N170、VPP等成分没有受到面孔情绪的影响, 而额中央位置的N300波幅显示情绪(正性与负性)面孔与中性面孔加工的差异。重要的是, N300波幅出现奖赏预期与情绪的交互作用, 正、负情绪加工效应以及负性偏向效应受奖赏预期的差异性影响。正性情绪加工效应不受奖赏预期的影响, 而负性情绪加工效应和负性偏向效应在奖赏预期条件下显著大于无奖赏预期条件下。这些结果说明, 奖赏预期能够调节对面孔情绪的加工, 且不同加工进程中奖赏对情绪加工的调节作用不同。动机性信息调节注意资源的分配, 促进了个体在加工面孔情绪时的负性偏向。     

Putting some feeling into it--the conceptual and empirical relationships between the classic and emotional Stroop tasks: comment on Algom, Chajut, and Lev (2004)

D. Algom, E. Chajut, and S. Lev presented a series of definitional, conceptual, and empirical arguments in support of their conclusion that the classic and emotional Stroop effects are, in their words, "unrelated phenomena" (p. 336), such that the term emotional Stroop effect is a misnomer in reference to the relatively greater interference in ink color naming of emotional versus neutral words. These are strong claims. In this comment, the author critically examines each component of Algom et al.'s case and argues that, in fact, none of these components represents compelling evidence in support of their eventual conclusions.     

An ERP study on facial expression of emotion: comparison of linguistic and visual semantic decoding

The present research compared the semantic information processing of linguistic stimuli with semantic elaboration of nonlinguistic facial stimuli. To explore brain potentials (ERPs, event-related potentials) related to decoding facial expressions and the effect of semantic valence of the stimulus, we analyzed data for 20 normal subjects (M age = 23.6 yr., SD = 0.2). Faces with three basic emotional expressions (fear, happiness, and sadness from the 1976 Ekman and Friesen database), with three semantically anomalous expressions (with respect to their emotional content), and the neutral stimuli (face without an emotional content) were presented in a random order. Differences in peak amplitude of ERP were observed later for anomalous expressions compared with congruous expressions. In fact, the results demonstrated that the emotional anomalous faces elicited a higher negative peak at about 360 msec., distributed mainly over the posterior sites. The observed electrophysiological activity may represent specific cognitive processing underlying the comprehension of facial expressions in detection of semantic anomaly. The evidence is in favour of comparability of this negative deflection with the N400 ERP effect elicited by linguistic anomalies.     

Neural mechanisms of affective interference in schizotypy

Negatively valenced stimuli foster cognitive impairment in schizotypy and schizophrenia. To identify relevant brain mechanisms, the authors had 16 positive-schizotypy and 16 control participants perform an emotional Stroop task, judging the ink color of negative and neutral words during functional magnetic resonance imaging (fMRI) of regional brain activity. Schizotypy individuals showed increased right and decreased left activity in dorsolateral prefrontal cortex, indicating a deficit in maintenance of attentional set in the presence of negative emotional distractors. They also showed abnormal activity in ventral limbic areas, including decreased activity in nucleus accumbens and increased activity in hippocampus and amygdala, a circuit involved in the integration of cognitive and affective processes. These results indicate that aspects of emotion-cognition processes and the brain mechanisms that implement them are similar in schizotypy and schizophrenia.     

The role of valence and frequency in the emotional Stroop task

People are generally slower to name the color of emotion-laden words than they are to name that of emotionally neutral words. However, an analysis of this emotional Stroop effect (Larsen, Mercer, & Balota, 2006) indicates that the emotion-laden words used are sometimes longer, have lower frequencies, and have smaller orthographic neighborhoods than the emotionally neutral words. This difference in word characteristics raises the possibility that the emotional Stroop effect is partly caused by lexical rather than by emotional aspects of the stimuli-a conclusion supported by the finding that reaction times to name the color of low-frequency words are longer than those for high-frequency words (Burt, 2002). To examine the relative contributions of valence and frequency in color naming, we had 64 participants complete an experiment in which each of these variables was manipulated in a 3 x 2 factorial design; length, orthographic neighborhood density, and arousal were balanced. The data indicate that valence and word frequency interact in contributing to the emotional Stroop effect.     

Experimental and Self-Reported Indices of Childhood Abuse Using the Binghamton Childhood Abuse Screen

This study describes the validation of the Binghamton Childhood Abuse Screen (BCAS) using response latencies on an emotional Stroop task as a criterion measure. Sixty-four male undergraduate participants were selected based on their responses to the BCAS and a brief screen of their abuse history. Participants completed an emotional Stroop task in which they named the colors of neutral, positive, and abuse words. Participants scoring high on the BCAS exhibited greater response latencies to abuse words than participants scoring low on the BCAS. No group differences were found for positive words. The results provide support for the validity of the BCAS.