Analgesic effects of posthypnotic suggestions and virtual reality distraction on thermal pain

The individual and combined effects of posthypnotic suggestion (PHS) and virtual reality distraction (VRD) on experimentally induced thermal pain were examined using a 2 x 2, between-groups design. After receiving baseline thermal pain, each participant received hypnosis or no hypnosis, followed by VRD or no VRD during another pain stimulus. Consistent with the hypothesis that hypnosis and VRD work via different mechanisms, results show that posthypnotic analgesia was moderated by hypnotizability but VRD analgesia was not. The impact of PHSs for analgesia was specific to high hypnotizables, whereas VRD was effective independent of hypnotizability. Results also show a nonsignificant but predicted pattern for high hypnotizables: Audio hypnosis combined with VRD reduced worst pain 22% more and pain unpleasantness 25% more than did VRD alone. Theoretical and clinical implications are discussed.     

Some effects of stimulant medication on response allocation: a double-blind analysis

Children who are diagnosed with attention deficit hyperactivity disorder (or who engage in behavior consistent with such a diagnosis) are often prescribed stimulant medications for hyperactive or inattentive behaviors. However, the mechanisms by which stimulant medications affect individuals' behavior are rarely evaluated. The purpose of the current study was to evaluate the effects of stimulant medication on response allocation when antecedents and consequences were held constant and equated. Results indicated that the presence of an amphetamine medication (Adderall) influenced response allocation across two concurrently available responses while all other stimulus conditions were held constant.     

Compliance with homework to employ self-instructions in controlling ice water pain: an analogue to counseling

40 women were taught to use self-statements to cope with pain caused by ice water. The trainer used four different strategies for reassigning a homework task of using self-statements to cope with pain produced by immersing one hand in ice water. The strategies were equally effective in eliciting compliance with the homework assignment.     

Acupuncture and emotion: the influence of acupuncture anesthesia on the sensory and emotional components of pain

Objective indices (heart rate, perspiration quantity, finger plethysmograph curves, and facial expression) and subjective indices (sensory and emotional subject reports) were recorded for 25 young Chinese adults (16 men, 9 women) during and after the simultaneous application of a strong pain stimulus and either foot classical (alloneural points Tsusanli and Yanglingchuan) or hand classical (alloneural points Hegu and Neiguan) acupuncture. Both forms of acupuncture were equally effective, showing that stimulation of the same nerve is not essential for pain relief. Acupuncture assuaged the emotional, but not the sensory, response to the painful stimulation.     

The effects of vicarious experience on pain termination and work avoidance: a replication

Clinical research suggests that vicarious experience plays an important role in the development of pain behavior but only one experimental study has shown that prior exposure to a model's reaction to a pain stimulus affects a subject's subsequent reaction to that stimulus. The purpose of the present investigation was to replicate this experimental study. Twenty-two experimental subjects viewed a film of a model in pain who either terminated a work task quickly (high-avoidant) or not quickly (low-avoidant). Subjects then performed the same work task while exposed to the same pain stimulus. The results indicated that subjects exposed to the high-avoidant model tolerated the pain stimulus for significantly fewer seconds and did significantly less work compared to the low-avoidant model subjects. As predicted, no group differences were observed on work speed or work accuracy. The results provide further evidence for the role of vicarious processes in the development of reactions to painful stimuli.     

After images and pain tolerance: a descriptive study on their interrelationship

After images are based on physiological processes, they can also be treated as subjective phenomena with a psychological meaning. This statement also applies to pain. The basic working hypothesis of this study concerned the relationship between the two phenomena. Forty-one respondents (23 females, 18 males, age range 20-45 years) were given the Cold Pressor Test and the Serial After Image Technique. The data analysis was done by means of cross-tables and an exploratory optimal scaling program (OVERALS). Three pain tolerance groups (low, medium, high) could be differentiated fairly well on the basis of the after image characteristics of the respondents. Pain intolerant respondents more frequently had small and "immature" after images, whereas highly pain tolerant respondents had more large and "mature" after images. The implications of these results for a bio-psycho-social theoretical frame of reference for pain are discussed.     

Fitness effects on the cognitive function of older adults: a meta-analytic study

A meta-analytic study was conducted to examine the hypothesis that aerobic fitness training enhances the cognitive vitality of healthy but sedentary older adults. Eighteen intervention studies published between 1966 and 2001 were entered into the analysis. Several theoretically and practically important results were obtained. Most important, fitness training was found to have robust but selective benefits for cognition, with the largest fitness-induced benefits occurring for executive-control processes. The magnitude of fitness effects on cognition was also moderated by a number of programmatic and methodological factors, including the length of the fitness-training intervention, the type of the intervention, the duration of training sessions, and the gender of the study participants. The results are discussed in terms of recent neuroscientific and psychological data that indicate cognitive and neural plasticity is maintained throughout the life span.     

Pain as a motivator of smoking: effects of pain induction on smoking urge and behavior

Tobacco smoking has been associated with the development and exacerbation of chronically painful conditions. Conversely, there is reason to believe that smokers may be motivated to use tobacco as a means of coping with their pain. To date, no controlled, experimental studies have tested for a causal relationship between pain and smoking motivation. The primary aim of the current study was to test the hypothesis that laboratory-induced cold pressor pain would enhance smoking motivation, as measured by self-reported urge to smoke and observation of immediate smoking behavior. Smokers (N=132) were randomly assigned to either pain or no pain conditions. Results indicated that situational pain increased urge ratings and produced shorter latencies to smoke. The relationship between pain and increased urge to smoke was partially mediated by pain-induced negative affect. The relationship between pain and shorter latency to smoke was fully mediated by pain-induced urge to smoke. This study provides the 1st experimental evidence that situational pain can be a potent motivator of smoking.     

Sequential effects on speeded information processing: a developmental study

Two experiments were performed to assess age-related changes in sequential effects on choice reaction time (RT). Sequential effects portray the influence of previous trials on the RT to the current stimulus. In Experiment 1, three age groups (7-9, 10-12, and 18-25 years) performed a spatially compatible choice task, with response-to-stimulus intervals (RSIs) of 50 and 500 ms varied between trial blocks. In Experiment 2, three age groups (7-9, 15-16, and 18-25 years) performed the task with spatial stimulus-response (S-R) mappings (compatible versus incompatible) varied between participants. For adults, the experiments yielded a pattern of sequential effects suggestive of "automatic facilitation" (i.e., a first-order repetition effect and a higher order benefit-only pattern for short RSIs) and "subjective expectancy" (i.e., a first-order alternation effect and a higher order cost-benefit pattern for long RSIs). Automatic facilitation was more pronounced for incompatible responses than for compatible responses. Both experiments showed the anticipated decrease in automatic facilitation with advancing age. Finally, the first-order alternation effect showed the predicted age-related increase, but the cost-benefit pattern revealed an opposite trend, suggesting that the first-order and higher order indexes of subjective expectancy may relate to dissociable mechanisms.     

The effects of the introduction of medication on the psychoanalytic process: a case study

The past fifteen years have seen a marked change in the attitude of psychoanalysts toward the use of medication in psychoanalysis, yet few detailed case studies have appeared in which the effects of the introduction of a medication on the psychoanalytic process have been studied. A plea for fluoxetine (Prozac) as a weight-loss aid, from a female patient whose analysis had progressed satisfactorily, set in motion a remarkable series of events. Her mood brightened, she rapidly lost weight, and she ultimately realized that she had the fantasy of being impregnated, all of which represented the reenactment of crucial childhood experiences. The most significant change in the psychoanalytic process was a newfound ability to experience critical thoughts and feelings, which previously had been prohibited by her harsh superego. At first both patient and analyst believed that the medication had "softened" her superego, but reexamination of the data revealed that most, if not all, of the changes could be attributed to the transference meaning of the collaboration rather than to the effects of the drug.     

The effects of overcorrection: a case study

The effects of overcorrection on multiple problems were studied in a single case. Whilst the techniques proved effective, they were extremely time-consuming and during treatment periods there were large increases in collateral behavior. Clinical implications of these findings are discussed.     

The effects of incorrect pain expectations on acquired fear and pain responses

Previous experimental research on the effects of incorrect intensity expectations of aversive events can be criticized because intensity expectations were not manipulated independently from changes in objective intensity. The present study aims at investigating the effects of incorrect intensity expectations on the immediate and later responses to a painful stimulus, and on the acquisition of anticipatory responses, with proper experimental control. Subjects (n = 62) received 20 painful stimuli of varying intensity. In the control group intensities were correctly signalled on all trials by an analogue signal. On 3 trials the signal was too large in the overprediction condition, and too small in the underestimation condition. Underpredicted painful experiences were related to subsequent higher pain responses on the physiological level, but not on the subjective level; and to increased anticipatory responses (increased pain expectations, uncertainty, subjective fear, skin conductance responses). Skin conductance level also indicated increased fear after underpredicted experiences. Overpredicted painful experiences were related to a faster decrease in subjective fear compared to the control group, but did not influence other variables. The findings support the notion that underpredictions contribute to the acquistion of fear and disrupt habituation processes. The asymmetrical processing of the two kinds of incorrectly predicted experiences is discussed.     

Fear of the beast: a prospective study on the effects of negative information on childhood fear

The current study examined the effects of negative information on the enhancement of childhood fear. A large group of normal primary school children aged between 4 and 12 years (N=285) received either negative or positive information about an unknown, doglike animal, called 'the beast'. Children's fears were assessed at three points in time: before, directly after, and one week after the information about the beast was provided (i.e., pre-, post- and follow-up assessment). Results showed that type of information changed children's fear of the beast in the predicted direction with negative information increasing fear levels and positive information decreasing fear levels. This was not only the case directly after the experimental manipulation but also at one week follow-up. Furthermore, fear of the beast appeared to generalize, that is, children who became more fearful of the beast after receiving negative information, also became more apprehensive of other dogs and predators.     

Acute effects of viloxazine HCl and flurazepam when given alone and in combination on sleep EEG: A double-blind interaction study with normals

Viloxazine, an aryl-oxypropanolamine type β-adreno-receptor antagonist, has been used in the treatment of depression. In a double-blind drug interaction study with flurazepam, a commonly used benzodiazepine hypnotic, viloxazine administered alone decreased the amount of time spent in REM sleep, increased the amount of time in the “light” stages of sleep, and increased the number of transitions to awake. However, no interactive effects of the combined administration of viloxazine and flurazepam could be detected.     

Money versus pain: experimental study of a conflict in humans.

Ten healthy human males volunteered to be subjects in an experiment in which they were to be paid to endure a painful sensation. This sensation was produced by isometric muscular contraction in the thighs. For each of six sessions the subjects received either a payment that was changed for each session (0.2, 0.5, 1.25, 3.125, 7.8125 French francs per 20 s) or a lump sum. At the beginning of a session, the subjects assumed a seated position against a wall, but without a seat, and the duration for which they could hold this position was the chief variable measured. Heart rate, blood pressure, and magnitude estimation of pain were also recorded periodically throughout each session. Pain was reported after a mean delay of 15 +/- 7 s (SE), and the magnitude estimates then increased linearly with time. The duration of maintaining the painful position increased linearly in relation to the logarithm of the increase in the amount of payment. Thus, utility of money decreased when pitted against pain.