Vagus nerve stimulation: a new form of therapeutic brain stimulation

Although the vagus nerve has traditionally been considered to perform efferent functions, in reality it performs significant afferent functions as well, carrying information from the body, head, and neck to the brain. Preliminary studies examining this afferent activity led to the theory that vagus nerve stimulation (VNS) could successfully control seizure activity in persons who are refractory to antiepileptic medications. Unlike other forms of brain stimulation, VNS is unable to directly stimulate multiple discrete areas of the brain; however, through several pathways, it is able to relay sensory information to higher brain regions. An implantable VNS device known as the VNSTM NeuroCybernetic Prosthesis (NCP) System has been used in approximately 9,000 epilepsy patients in Europe and the United States since 1994. The implant has reduced seizure frequency by an average of 25% to 30%, with minimal side effects. Studies underway are also showing some degree of success in the management of treatment-refractory depression. The future efficacy of the implantable system in other disorders may depend on whether the implant can be more precisely focused to affect different brain regions. Research in this area is underway.     

Personality pathology severity,cluster type and specific therapeutic interventions in outpatient psychotherapy

We explored the relationship between severity of personality pathology, cluster type and therapeutic interventions (psychodynamic–interpersonal [PI] and cognitive–behavioural [CB]) in 76 outpatients across two early sessions (3rd and 9th) of psychodynamic psychotherapy, while accounting for patients' baseline global symptom severity. Pretreatment personality pathology severity was assessed using the Personality Disorder Index (PDI), where DSM‐IV Axis II PD was assigned a value of 2, subclinical traits and features were assigned a 1 and absence of Axis II psychopathology was assigned a 0. Interrater reliability of personality pathology severity was excellent (ICC [1, 1]: 0.85). Interrater agreement for Cluster A (κ = 0.75), Cluster B (κ = 0.92) and Cluster C (κ = 0.70) was high. Interventions were coded with Comparative Psychotherapy Process Scale (CPPS) from videotapes, and reliability was excellent (CPPS‐PI = 0.86; CPPS‐CB = 0.78). Stepwise linear regressions indicated that therapists' focus on mood shift/topic avoidance (B = 0.29, p = .009) and future events (B = ?0.26, p = .020) predicted Axis II severity. Overall use of PI techniques and Cluster A personality disorder (CLA) were positively correlated (r = .312, p = .006). Stepwise binomial logistic regressions indicated that therapists' focus on uncomfortable feelings (B = 1.915, p = .008) and explaining rationale behind approach (B = 1.276, p =. 038) predicted CLA. All results remained significant when controlling for patients' baseline general symptomatology (Brief Symptom Inventory‐Global Severity Index [BSI‐GSI]), except for the relation between explaining rationale and CLA. Discussion highlights how using psychodynamic treatment model, therapists' focus on patient's in‐session affect expression and explaining rationale behind approach are highly relevant when working with CLA patients.     

Color categories are not universal: replications and new evidence from a stone-age culture

The authors sought to replicate and extend the work of E. Rosch Heider (1972) on the Dani with a comparable group from Papua, New Guinea, who speak Berinmo, which has 5 basic color terms. Naming and memory for highly saturated focal, non-focal, and low-saturation stimuli from around the color space were investigated. Recognition of desaturated colors was affected by color vocabulary. When response bias was controlled, there was no recognition advantage for focal stimuli. Paired-associate learning also failed to show an advantage for focal stimuli. Categorical Perception effects for both English and Berinmo were found, but only at the boundaries of existing linguistic categories. It is concluded that possession of linguistic categories facilitates recognition and influences perceptual judgments.     

Factors affecting responses to Likert type questionnaires: introduction of the ImpExp,a new comprehensive model

The major purpose of this paper is to propose a comprehensive model describing the effects of response sets within the theory framework of the stages of responding to questionnaires, and taking into account the effects of collectivist and individualist attributes within cross-cultural contexts. The introduction of this model aims to provide a construct that may help minimize biases in questionnaire-based research as well as providing new directions for theoretical and empirical research in the field of response sets.

Killing, letting die, and withdrawing aid

One of the aims of this article is to contribute to the identification of the empirical criteria governing the use of the concepts of killing and letting die. I will not attempt a comprehensive analysis of the concepts but will limit the inquiry to certain problematic cases -- namely, cases involving the removal or withdrawal of life-supporting aid or protection. The analysis of these cases will, however, shed light on the criteria for distinguishing killing and letting die in other cases as well. My overall aims in the article are partly constructive and partly skeptical. I hope to advance our understanding of the nature of the distinction between killing and letting die. This, I believe, will enable us to defend the moral relevance of the distinction against certain objections -- in particular, objections that claim that the distinction fails to coincide with commonsense moral intuitions. Yet I will suggest that, as we get clearer about the nature of the distinction and the sources of its intuitive appeal, it may seem that the intuitions it supports are not so well grounded as one could wish.     

Color,context, and compositionality

Color adjectives have played a central role in work on language typology and variation, but there has been relatively little investigation of their meanings by researchers in formal semantics. This is surprising given the fact that color terms have been at the center of debates in the philosophy of language over foundational questions, in particular whether the idea of a compositional, truth-conditional theory of natural language semantics is even coherent. The challenge presented by color terms is articulated in detail in the work of Charles Travis. Travis argues that structurally isomorphic sentences containing color adjectives can shift truth value from context to context depending on how they are used and in the absence of effects of vagueness or ambiguity/polysemy, and concludes that a deterministic mapping from structures to truth conditions is impossible. The goal of this paper is to provide a linguistic perspective on this issue, which we believe defuses Travis’ challenge. We provide empirical arguments that color adjectives are in fact ambiguous between gradable and nongradable interpretations, and that this simple ambiguity, together with independently motivated options concerning scalar dimension within the gradable reading accounts for the Travis facts in a simpler, more constrained, and thus ultimately more successful fashion than recent contextualist analyses such as those in Szabó (Perspectives on semantics, pragmatics and discourse: A festschrift for Ferenc Kiefer, 2001) or Rothschild and Segal (Mind Lang, 2009).     

Color,Relativism, and Realism

It is plausible to think that some animals perceive the world as coloreddifferently from the way humans perceive it. I argue that the best way ofaccommodating this fact is to adopt perceiver-relativism, the view that colorpredicates express relations between objects and types of perceivers.Perceiver-relativism makes no claim as to the identity of color properties;it is compatible with both physicalism and dispositionalism. I arguehowever for a response-dependence version of it according to which an object counts as red (for a type of perceiver) iff it standardly looks red to normal perceivers (of that type). Finally, I develop a notion of minimal realism on which this account counts as realist despite its subjectivist elements, in that it is committed to the objectivityof truth.