老年人记忆补偿的长期稳定性和变异性：来自维多利亚纵向研究的证据

两种记忆状况组来自于参与加拿大维多利亚纵向研究(VLS)的老年人原样本。一种是未受损伤的控制组(NIC), 另一种是轻度记忆损伤组(MMD)。在基线水平和纵向水平上(即5次追踪或12年)比较了他们在日常生活中对记忆补偿技术的使用。我们使用多水平模型(以年龄和教育水平为协变量)来检验基线水平的差异和长期的变化模式。基线的结果表明MMD组被试报告了近期在日常生活中使用记忆补偿策略方面有更大的增长。纵向的结果表明记忆补偿的使用在12年中具有明显的稳定性, 但是与努力相关的补偿机制存在显著组间差异。教育水平这一协变量(可认为是潜在的认知储备指标)和三种记忆补偿策略随时间的不同变化相关。     

感数的认知机制：从注意到工作记忆

感数(subitizing)是对小数精确而迅速的知觉, 它反映了有机体的一种基本数量表征能力。研究者曾一度认为感数是一个前注意的并行加工过程, 近年来的一些研究发现感数是需要注意资源的, 但是注意资源假设不能有效解释感数与计数的分离。为解决这一困惑, 本文综述了感数和视空间工作记忆的相似性, 在此基础上提出一种新的观点来解释感数的认知机制：视空间工作记忆容量决定了个体一次能精确知觉到的客体的数量, 而注意决定了哪些信息进入视空间工作记忆。     

Performance variability is related to change in cognition: evidence from the Victoria Longitudinal Study

Performance variability across repeated task administrations may be an important indicator of age-related cognitive functioning. In the present investigation, the authors examined whether age differences and change in inconsistency were related to 6-year (3 occasion) cognitive change. Inconsistency scores were computed from 4 reaction time tasks performed by 446 older adults (54-89 years). Replicating previous cross-sectional results, greater inconsistency was observed for older participants even after controlling for differences in response speed. New longitudinal results demonstrated (a) associations between inconsistency at baseline measurement and 6-year change in cognitive performance; (b) longitudinal change in inconsistency; and (c) intraindividual covariation between 6-year change in inconsistency and 6-year change in level of cognitive function. These findings support the view that performance variability serves as a marker of cognitive aging.     

老化对睡眠依赖性记忆巩固的影响

随着老化的发生和发展, 老年人的睡眠和记忆问题变得越来越突出。研究显示老年人针对程序性记忆的睡眠依赖性巩固能力受损, 而针对陈述性记忆的睡眠依赖性巩固研究结果尚存分歧。此外, 患有神经退行性疾病的老年人在正常老化的基础上伴有情景记忆睡眠依赖性巩固能力受损。未来研究应考虑同步采集脑电和脑成像数据, 探索增龄通过睡眠影响记忆的神经通路, 尝试搭建老化、睡眠以及记忆三因素的交互模型, 并从睡眠对记忆巩固影响的角度提出针对老年人记忆问题的干预措施。     

教育水平在认知老化中的作用

为考察教育水平在认知老化中的作用,分别使用横断数据和干预数据分析教育水平对认知老化的影响模式。对51名58～83岁的城市社区老年人实施加工速度测验和基本心理能力测验。随机选取25名被试作为干预组接受加工速度训练。被试在前测后第8周接受与前测内容相同的后测。横断分析的结果显示,在特定的认知测验中,教育水平对认知能力的年龄差异有调节作用。干预数据的分析结果显示,加工速度干预效果显著,且对词汇流畅性有迁移作用。但相关分析和回归分析的结果则表明,教育水平在促进老年人干预收益和迁移方面的作用不显著。在获取和应用新知识方面,教育水平的作用并不显著,其在认知老化中的作用可能更多地表现为对固有认知功能的保护。     

Dramatic Increase in Heritability of Cognitive Development From Early to Middle Childhood: An 8-Year Longitudinal Study of 8,700 Pairs of Twins

ABSTRACT— The generalist genes hypothesis implies that general cognitive ability ( g ) is an essential target for understanding how genetic polymorphisms influence the development of the human brain. Using 8,791 twin pairs from the Twins Early Development Study, we examine genetic stability and change in the etiology of g assessed by diverse measures during the critical transition from early to middle childhood. The heritability of a latent g factor in early childhood is 23%, whereas shared environment accounts for 74% of the variance. In contrast, in middle childhood, heritability of a latent g factor is 62%, and shared environment accounts for 33%. Despite increasing importance of genetic influences and declining influence of shared environment, similar genetic and shared environmental factors affect g from early to middle childhood, as indicated by a cross-age genetic correlation of .57 and a shared environmental correlation of .65. These findings set constraints on how genetic and environmental variation affects the developing brain.     

Spatial Working Memory in Aging and Mild Cognitive Impairment: Effects of Task Load and Contextual Cueing

ABSTRACT

Mild Cognitive Impairment (MCI) is characterized by episodic memory deficits, while aspects of working memory may also be implicated, but studies into this latter domain are scarce and results are inconclusive. Using a computerized search paradigm, this study compares 25 young adults, 25 typically aging older adults and 15 amnestic MCI patients as to their working-memory capacities for object-location information and potential differential effects of memory load and additional context cues. An age-related deficit in visuospatial working-memory maintenance was found that became more pronounced with increasing task demands. The MCI group additionally showed reduced maintenance of bound information, i.e., object-location associations, again especially at elevated memory load. No effects of contextual cueing were found. The current findings indicate that working memory should be considered when screening patients for suspected MCI and monitoring its progression.     

Cognitive Functioning in Aging and Dementia: The Kungsholmen Project

The Kungsholmen Project (KP) is a community-based longitudinal study of aging and dementia targeting the 75+ population. In this article, we review empirical studies with a cognitive focus from the KP. The main findings indicate that (a) there is an age-related decline for some cognitive domains (e.g., episodic memory, verbal fluency, visuoconstructive skill, psychomotor speed), but not for others (e.g., primary memory, visuoperceptive skill, motor-hand coordination), (b) multiple individual-difference variables within demographic (e.g., sex, education) life-style (e.g., activity levels), genetic (e.g., apolipoprotein E genotype), and health-related (e.g., vitamin B deficiency, depression, diabetes) domains are related to late-life cognitive functioning, (c) a potential for improving cognitive performance – a reserve capacity – is present also among very old adults, (d) the 2 most common dementia diseases, Alzheimer’s disease (AD) and vascular dementia (VaD), affect cognition in a strikingly similar manner, (e) the role of individual-difference variables in cognitive functioning is markedly reduced in dementia – the pathogenesis itself may overshadow the influence of other variables, and (f) there is a long preclinical period in dementia during which cognitive deficits are detectable. As is true with the other projects represented in this issue, the KP portrays a rather diversified picture of cognitive aging, although systematic patterns are evident with regard to the variability of late-life cognitive functioning.     

Cognitive Vulnerability to Depressive Symptoms in Children: The Protective Role of Self-efficacy Beliefs in a Multi-Wave Longitudinal Study

The current multi-wave longitudinal study on childhood examined the role that social and academic self-efficacy beliefs and cognitive vulnerabilities play in predicting depressive symptoms in response to elevations in idiographic stressors. Children (N?=?554; males: 51.4 %) attending second and third grade completed measures of depressive symptoms, negative cognitive styles, negative life events, and academic and social self-efficacy beliefs at four time-points over 6 months. Results showed that high levels of academic and social self-efficacy beliefs predicted lower levels of depressive symptoms, whereas negative cognitive styles about consequences predicted higher depression. Furthermore, children reporting higher social self-efficacy beliefs showed a smaller elevation in levels of depressive symptoms when reporting an increases in stress than children with lower social self-efficacy beliefs. Findings point to the role of multiple factors in predicting children’s depression in the long term and commend the promotion of self-efficacy beliefs and the modification of cognitive dysfunctional styles as relevant protective factors.     

Longitudinal Changes in Memory Performance and Processing Speed in Old Age abstract Keywords

The speed theory of cognitive aging posits that an age-related slowing of processing speed leads to impairments in higher order cognitive functions, such as memory. However, only few studies have examined the relationship between longitudinal changes in processing speed and longitudinal changes in memory performance. In the present study, data of 474 older adults (T1: 59–65 years) from the Interdisciplinary Longitudinal Study on Adult Development (ILSE) were used to investigate whether changes in speed and in memory were associated over a 4-year period. Performance changes in both constructs were analyzed using latent change factor models. Results show that latent changes in processing speed and latent changes in memory performance correlated with 0.61. This association is considerably lower than what would have been expected from cross-sectional data. Our longitudinal results suggest that although speed changes explain a substantial proportion of variance in memory changes, additional explanatory factors must be taken into consideration.     

Self-Efficacy and Memory Aging: The Impact of a Memory Intervention Based on Self-Efficacy

ABSTRACT

A multifactorial training program was developed for older adults, to improve self-efficacy and memory performance. Elements designed to raise self-efficacy were integrated into class discussions, homework readings, and practice exercises, including an emphasis on memory potential at any age, self-set goals, and opportunities for mastery. Strategy training focused on association, organization, attention, imagery, and PQRST. Significant improvements for the training group, as compared to a wait-list control group, were observed for memory self-efficacy, locus of control, name recall and story recall. Trained participants were using effective strategies more so than the control group. Final test scores were predicted by self-efficacy, condition assignment, and baseline ability (with some variation across the three tasks). These findings suggest that an integrated and comprehensive training program that incorporates principles of self-efficacy theory has great potential for improving older adults' memory ability.     

Aging and Autobiographical Memory: The Long and Bumpy Road

This article serves as an introduction to this special issue of Journal of Adult Development that deals with the topic of aging and autobiographical memory. Methodological issues, empirical findings, and theoretical frameworks that bear on older adults' autobiographical recall are discussed. Special emphasis is placed on an examination of the factors that underlie the offset of infantile amnesia and the reminiscence bump. An integrative approach to the study of aging and autobiographical memory is proposed that brings together paradigms from experimental psychology, clinical neuropsychology, and neuroimaging.     

The Contributions of Memory and Attention Processes to Cognitive Abilities

In two experiments, the contributions of memory and attention processes to the cognitive abilities of reasoning and perceptual speed were investigated. Two measures of speed of information retrieval from long-term and short-term memory (Posner paradigm, Sternberg paradigm) and two attention measures (continuous attention test, attention switching test) were included in the first experiment (N = 220). The memory tests led to correlations with the measures of cognitive abilities, whereas the attention test did not. The same tests as well as one additional memory test and one attention test (working memory test, test of covert orientation) were administered in the second experiment (N = 116). Again, the memory tests led to the larger correlations with the measures of cognitive abilities. Two components were obtained in components analysis, of which the first was characterized by high loadings of the memory tests and the second by high loadings of the attention tests. Only the memory component contributed to the prediction of cognitive abilities.     

情节记忆中的前摄干扰：神经心理药物学及计算认知建模研究

记忆障碍患者的前摄干扰敏感性显著上升, 但其认知机制仍不清楚。结合神经心理药物学实验和计算认知建模方法对这一问题进行了研究。实验为被试内、双盲设计, 由健康成年人进行两次词对任务的学习, 间隔一周, 两次测试中或注射0.03 mg/kg体重咪唑安定或注射相同浓度的生理盐水。学习过程中及学习结束后进行测试, 要求被试根据线索词回忆靶词。实验结果发现, 注射咪唑安定可引起情节记忆的短时下降, 两种注射条件下均呈现明显的前摄干扰; 与生理盐水条件相比, 注射咪唑安定时引起的前摄干扰显著较高。基于SAC (Source of Action Confusion)的计算认知建模结果较好地拟合了实验数据。这一结果提示, 编码困难可能是记忆障碍患者前摄干扰敏感性较高的主要原因。     

Reading Comprehension in Aging: The Role of Working Memory and Metacomprehension

This study examines age-related differences in reading comprehension analyzing the role of working memory and metacomprehension components in a sample of young (18–30 years), young-old (65–74 years), and old-old (75–85 years) participants. Text comprehension abilities were measured by a standardized test, including two texts: a narrative and an expository text. The elderly's reading comprehension performance, when compared to the norm, emerged to be adequate. More specifically, the young-old showed an equivalent level of comprehension as the young adults for the narrative text. However, a clear age-related decline was found in the case of the expository text. Hierarchical regression analyses showed that working memory capacity, as well as different metacomprehension components but not age, are the key aspects in explaining the different patterns of changes in the comprehension of narrative and expository texts.