Does drug mis-instrumentalization lead to drug abuse?

Understanding the perceived benefits of using drugs to achieve specific mental states will provide novel insights into the reasons individuals seek to use drugs. However, the precision of attempts to instrumentalize drugs is unclear both across drugs and individuals. Moreover, mis-instrumentalization, defined as discrepancies between such endpoints, may have relevance to understanding the relation among use, abuse, and addiction.     

Can drug patents be morally justified?

This paper offers a few elements of an answer to the question to what extent drug patents can be morally justified. Justifications based on natural rights, distributive justice and utilitarian arguments are discussed and criticized. The author recognizes the potential of the patents to benefit society but argues that the system is currently evolving in the wrong direction, particularly in the field of drugs. More than a third of the world’s population has no access to essential drugs. The working of the patent system is an important determinant of access to drugs. This paper argues that drug patents are not easily justified and that the ‘architecture’ of the patent system should be rethought in view of its mission of benefiting society. An earlier version of this paper was presented at an international conference, “The Ethics of Intellectual Property Rights and Patents,” held in Warsaw, Poland on 23–24 April, 2004. The author is a part-time Senior Research Fellow of the Fund for Scientific Research, Department of Philosophy and Moral Science, Ghent University (Belgium) and a part-time Professor, Department of General Economics, University of Antwerp (Belgium).     

Preventing drug abuse: where are we now?

Counselors in many settings are involved in the development and implementation of drug abuse prevention programs. It is therefore essential that counselors be as informed as possible about the characteristics of drug abusers and about the drug abuse prevention programs that seem to hold some promise of being effective. This article provides some of this information by examining the research literature and extracting from it the common themes that have meaning for counselors in almost any population.     

The drug‐crime nexus among adolescents and their peers

The purpose of this paper is to determine the nature of the drug‐crime relationship by exploring the influence of friend behaviors on both adolescent delinquent and substance using behavior. The sample consists of 1381 adolescents evenly divided by gender into three age groups (12, 15 and 18 years old). In general, there is an increase in intensity of substance use from the youngest to the oldest age level with male and female levels being similar within each age group. There are both age and gender differences when examining delinquent behavior. There is a relationship between adolescent drug use and crime (especially among males), however this relationship is relatively modest. In addition, while friends’ behavior is a very strong predictor of the same type of behavior in subjects, there are no strong crossover relationships. Thus, the hypothesis that both types of behavior are part of a specific deviant peer subculture is not confirmed.     

Do college studentsstill prefer companies without employment drug testing?

Two experiments examined the effects of drug testing policies on undergraduates' behavioral intentions and attitudes toward the company. Study 1 (n=267) manipulated type of drug testing and consequences of detected use. Study 2 (n=267) manipulated the presence of applicant and employee drug testing. Subjects in both studies showed stronger intentions to apply to a company with random employee testing than one with no employee testing. Study 2 also found that an interaction between company policy and subjects' attitudes toward drug testing affected attitudes toward the company. Both studies suggest that employee drug testing may now foster recruitment.Study 1 was conducted while the author was at Ohio University and was presented in an earlier version at the Eastern Psychological Association's 64th Annual Meeting, Arlington, VA, April 16–April 18, 1993.I thank Candie Burbick and Jamie Winters for their work as student assistants. I also thank Jane Kestner, Kim Mastrangelo, James Rogers, and the JBP reviewers for their suggestions.     

The “post” phase of deviant careers: Reintegrating drug traffickers

Although social scientists have examined the entry, intermediate, and exit phases of deviant careers, few have analyzed the reintegration of former occupational deviants into the conventional society and legitimate economy. For this follow‐up study, 10 years after conducting a longitudinal ethnographic study of upper level drug dealers and smugglers, I returned to the field to see what had become of my former subjects. I describe the directions they have ventured and analyze the social and occupational effects of their years in the drug world on their subsequent lives. For drug dealers, whose careers follow a roughly patterned evolution through ascension, peak, and decline, reintegration serves as the postdealing phase of their deviant careers.     

Processes of early drug involvement in three inner‐city neighborhood settings

The present paper explores the drug use of a sample of inner‐city junior high school youths by examining a hypothesized, interactive relationship between the perceived toughness/drug use in their neighborhood and the youths’ demographic, neighborhood orientation/involvement, and drug use context factors in regard to their drug involvement. In support of our hypothesis, discriminant analysis indicated that different processes were reflected in the correlates of the youths’ involvement with drugs in the three settings. Implications of these findings for drug abuse treatment and prevention strategies are discussed.     

Project KICK: A school‐based drug education health promotion research project

The purpose of this research‐based design was to address drug prevention and health promotion strategies through the combination of: (1) parent education and involvement; (2) community partnership, and (3) positive peer influence. These strategies were implemented using a four‐cornered partnership among Florida State University, an elementary school, a middle school, and a community advisory board. Expected outcomes were improved self‐concept, improved drug knowledge and awareness, improved decision making and drug refusal skills, and improved perceptions of family coping and adaptability. Bimonthly parent education courses and weekly peer role modeling sessions between middle and elementary school students comprised the interventions for this research. Results were encouraging as increases were found in the predicted direction for the experimental group on all of the major variables.     

Animal models of drug addiction: Where do we go from here?

Compulsion and impulsivity are both primary features of drug addiction. Based on decades of animal research, we have a detailed understanding of the factors (both environmental and physiological) that influence compulsive drug use, but still know relatively little about the impulsive aspects of drug addiction. This review outlines our current knowledge of the relationship between impulsivity and drug addiction, focusing on cognitive and motor impulsivity, which are particularly relevant to this disorder. Topics to be discussed include the influence of chronic drug administration on impulsivity, the mechanisms that may explain drug-induced impulsivity, and the role of individual differences in the development of impulsive drug use. In addition, the manner in which contemporary theories of drug addiction conceptualize the relationship between impulsivity and compulsion is examined. Most importantly, this review emphasizes a critical role for animal research in understanding the role of impulsivity in the development and maintenance of drug addiction.     

The “pill popper”: A device for drug capsule self-administration by primates

An apparatus for establishing self-administration of drugs in capsule preparation form by nonhuman primates is described. The system includes a capsule loading unit combined with a pressurized liquid dispenser and mouth-operated drinking tube lever. Operation of the mouth lever results in forced ingestion of a capsule or other solid substance and a measured quantity of liquid. The components of the system are separately programmable and adjustable to permit shaping of pressurized liquid and capsule ingestion through successive approximations. Examination of absorption factors and temporal variables associated with delay of drug reinforcement onset, as well as precision in oral dosage, are thus possible in a model which approximates the most common method and features of drug self-administration in humans.     

Conners' Teacher Rating Scale for use in drug studies with children — An empirical study

Their classroom teachers rated 291 schoolchildren, grades kindergarten through 6, on Conners' Teacher Rating Scale, developed for and used widely in drug studies in children. Scores were found to be significantly lower than those reported for a similar group of 92 New York children and considerably less than those of a group of 64 children receiving medication for deviant behavior. Boys generally had higher scores for acting-out-type behavior while girls scored higher on neuroticism. The factor structure in this sample showed some differences from that in Conners' original analysis but they are insufficient for any change in the widely accepted scoring system, except perhaps to add a fifth factor of sociability.     

Female and male intravenous drug users not-in-treatment: Are they at differential risk for AIDS?

We describe and compare the drug-use patterns of ethnically diverse (45% white, 39% African American, 15% Hispanic) female and male intravenous drug users (IVDUs) not-in-treatment. Focusing on a group of hard-to-reach and economically disadvantaged IVDUs, we were able to document drug use patterns and practices that have been shown to place them at increased risk for AIDS. We were also able to examine if women IVDUs were at differential risk for AIDS in comparison to men IVDUs. Results indicated that female IVDUs practices may place them differentially at risk for contracting HIV because they were more likely than male IVDUs to share needles. When female IVDUs shared needles, they were also more likely than male IVDUs to share needles with a spouse or sexual partner. We argue that these results may be tied to gender role socialization and have important implications for designing interventions for female IVDUs.This research was supported by Grant DA01070 from the National Institute on Drug Abuse to the second author.     

Do the effects of a family intervention on alcohol and drug use vary by nativity status?

To examine whether the intervention effects of Familias Unidas, compared to community practice, on Hispanic adolescent alcohol and drug use varies by nativity status (i.e., U.S.-born and foreign-born). A total of 213 eighth grade Hispanic adolescents with behavior problems and their primary caregivers were assigned randomly to one of two conditions: Familias Unidas or Community Control. Participants were assessed at baseline and at 6, 18, and 30 months post baseline. Results showed that, the effects of Familias Unidas on alcohol use was moderated by nativity status. Specifically, Familias Unidas was efficacious in preventing/reducing alcohol use for U.S.-born youth, but not foreign-born. No moderating effects were found for drug use. These findings suggest that prevention interventions may be more efficacious in preventing/reducing alcohol use among certain Hispanic adolescent subgroups. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Matching therapeutic interventions to drug and alcohol abusers’ stage of motivation: The clients’ perspective

The present study aims to explore the issue of matching the appropriate therapeutic intervention according to the stage of readiness for change in addictive clients, following the model proposed by Prochaska and DiClemente in the 1980s. The study focuses solely on the perspectives of people with drug and alcohol problems, in contrast to previous ones which have been concerned with the researchers’ understandings and postulations of the issue under exploration. One of the most important findings of this study is that participants in the “early” stages of their readiness to change their addictive behaviour, irrespective of their gender or whether they had seen a therapist significantly prefer non-action-oriented therapeutic interventions than action-oriented interventions. Similarly, participants in the “later” stages, showed a significant preference to action-oriented than non-action interventions, irrespective of their gender or previous experience of counselling. It is suggested then that careful assessment of the stage of motivation and individual-tailored intervention should be an essential element of any treatment program for drug and alcohol addicted clients.     

The contribution of the cingulate cortex: treating depressive symptoms in first-episode drug naïve schizophrenia

BackgroundOur previous study has shown the cingulate cortex abnormalities in first-episode drug naïve (FEDN) schizophrenia patients with comorbid depressive symptoms. However, it remains largely unknown whether antipsychotics may induce morphometric change in cingulate cortex and its relationship with depressive symptoms. The purpose of this study was to further clarify the important role of cingulate cortex in the treatment on depressive symptoms in FEDN schizophrenia patients.MethodIn this study, 42 FEDN schizophrenia patients were assigned into depressed patients group (DP, n = 24) and non-depressed patients group (NDP, n = 18) measured by the 24-item Hamilton Depression Rating Scale (HAMD). Clinical assessments and anatomical images were obtained from all patients before and after 12-week treatment with risperidone.ResultsAlthough risperidone alleviated psychotic symptoms in all patients, depressive symptoms were decreased only in DP. Significant group by time interaction effects were found in the right rostral anterior cingulate cortex (rACC) and other subcortical regions in the left hemisphere. After risperidone treatment, the right rACC were increased in DP. Further, the increasing volume of right rACC was negatively associated with improvement in depressive symptoms.ConclusionThese findings suggested that the abnormality of the rACC is the typical characteristics in schizophrenia with depressive symptoms. It's likely key region contributing to the neural mechanisms underlying the effects of risperidone treatment on depressive symptoms in schizophrenia.