Cognitive discernible factors between schizophrenia and schizoaffective disorder

BackgroundSchizophrenia (SZ) and schizoaffective disorders (SA) are associated with cognitive deficits. Generally, a schizoaffective diagnosis is associated with better prognosis on the level of social integration. It is also well established that cognition is an important factor for good social outcome in schizophrenia. We hypothesized that, although patients suffering from SA share symptoms with SZ, they can be differentiated on the basis of neurocognitive function and that SA perform better in several domains.MethodPerformances of two groups SA (N = 13) and SZ (N = 44) were compared on several visual-motor tasks using CANTAB [Motor Screening (MOT), Reaction Time (RTI), Paired Associates Learning Task (PAL), and Stockings of Cambridge items (SOC)]. The two groups were matched for symptom severity. ANOVA with repeated measures was employed to determine whether any difference in cognitive scores during a 2-year period was significantly related to the diagnostic status.ResultsA significant and durable difference was observed between SZ and SA on motor screening and explicit memory tests where SA performed better.ConclusionNeurocognitive tests may be relevant for distinguishing schizoaffective from schizophrenia, chiefly via tests tapping into visuo-spatial and visuo-motor coordination abilities (e.g., paired associated learning and motor screening).     

Randomized Face-to-face vs. Home exercise interventions in pregnant women with gestational diabetes

ObjectivesEvaluate effects of a theoretically-based, semi-intensive (Face-to-Face; F2F) exercise intervention and minimum-contact (Home) exercise intervention to the standard care (Control) on exercise, its motivational determinants, blood glucose levels, and insulin use of pregnant women with gestational diabetes mellitus (GDM).DesignRandomized control trial with two intervention arms and control (standard care).MethodParticipants (N = 65) were randomized to a Control (standard prenatal care/GDM dietary counseling), Home (standard care + phone education/support + home exercise), or F2F (standard care + on-site education/support + guided exercise with instructor on 2 days/week) group from ∼20 weeks gestation to delivery. Assessments of exercise and motivational determinants were obtained at baseline (20-weeks gestation) and follow-up (32-weeks gestation). Blood glucose levels (fasting/postprandial mg/dL) and insulin use were extrapolated from medical records.ResultsAt the 32-week follow-up, the F2F group had significantly higher exercise min, pedometer steps/day, and motivational determinants (attitude, subjective norm, perceived control, intention) than controls (p's < 0.05) and significantly higher exercise min and subjective norm than the Home group (p's < 0.05); these effect sizes were medium-large (η² = 0.11-0.23). There was a medium effect (η² = 0.13) on postprandial blood glucose at 36-weeks gestation with the F2F group having lower values than controls. Although not significant, the F2F group started insulin later (33 weeks gestation) than the Home (27 weeks) and Control (31 weeks) groups.ConclusionA theoretically-based, F2F exercise intervention has multiple health benefits and may be the necessary approach for promoting exercise motivation and behavior among GDM women.     

Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance

Insulin regulates glucose uptake and storage in peripheral tissues, and has been shown to act within the hypothalamus to acutely regulate food intake and metabolism. The machinery for transduction of insulin signaling is also present in other brain areas, particularly in the hippocampus, but a physiological role for brain insulin outside the hypothalamus has not been established. Recent studies suggest that insulin may be able to modulate cognitive functions including memory. Here we report that local delivery of insulin to the rat hippocampus enhances spatial memory, in a PI-3-kinase dependent manner, and that intrahippocampal insulin also increases local glycolytic metabolism. Selective blockade of endogenous intrahippocampal insulin signaling impairs memory performance. Further, a rodent model of type 2 diabetes mellitus produced by a high-fat diet impairs basal cognitive function and attenuates both cognitive and metabolic responses to hippocampal insulin administration. Our data demonstrate that insulin is required for optimal hippocampal memory processing. Insulin resistance within the telencephalon may underlie the cognitive deficits commonly reported to accompany type 2 diabetes.     

Examining the roles of experiential avoidance and cognitive fusion on the effects from mindfulness to athlete burnout: A longitudinal study

ObjectivesAthlete burnout is a maladaptive outcome that is potentially detrimental for performance and wellbeing. Cross-sectional evidence suggests that mindfulness might be associated with athlete burnout via experiential avoidance and cognitive fusion. In the current study, we extend knowledge of these hypothesized mediational pathways using a longitudinal design.MethodsData was collected at three occasions with a three-month interval. A final sample of 280 elite Chinese athletes aged 15–32 years (M_age = 19.13; SD = 2.92; Female = 130) reported their mindfulness at Time 1, experiential avoidance and cognitive fusion at Time 2, and athlete burnout at Time 3. Structural equation modelling was adopted to examine the mediating roles of experiential avoidance and cognitive fusion on the effects from mindfulness to athlete burnout.ResultsWe found statistically meaningful directs effects from mindfulness (Time 1) to experiential avoidance and cognitive fusion (Time 2), which in turn influenced athlete burnout (Time 3). However, the direct effect from mindfulness at Time 1 to athlete burnout at Time 3 was non-significant. The indirect effects of experiential avoidance and cognitive fusion on the effects from mindfulness to athlete burnout were significant, providing longitudinal evidence that these two variables contribute meaningfully to the mindfulness-burnout pathway.ConclusionWith initial evidence for the mediating effects of experiential avoidance and cognitive fusion, future studies could consider using experimental designs to examine the potential changing mechanisms of mindfulness on reducing athlete burnout.     

Socioeconomic status and hippocampal volume in children and young adults

An individual's socioeconomic status (SES) is often viewed as a proxy for a host of environmental influences. SES disparities have been linked to variance in brain structures particularly the hippocampus, a neural substrate of learning and memory. However, it is unclear whether the association between SES and hippocampal volume is similar in children and adults. We investigated the relationship between hippocampal volume and SES in a group of children (n = 31, age 8–12 years) and a group of young adults (n = 32, age 18–25 years). SES was assessed with four indicators that loaded on a single factor, therefore a composite SES scores was used in the main analyses. Hippocampal volume was measured using manual demarcation on high resolution structural images. SES was associated with hippocampal volume in the children, but not in adults, suggesting that in childhood, but not adulthood, SES‐related environmental factors influence hippocampal volume. In addition, hippocampal volume, but not SES, was associated with scores on a memory task, suggesting that net effects of postnatal environmental factors, captured by SES, are more distal determinants of memory performance than hippocampal volume. Longitudinal investigation of the association between SES, hippocampal volume and cognitive functioning may further our understanding of the putative neural mechanisms underlying SES‐related environmental effects on cognitive development.     

Default mode network connectivity and social dysfunction in children with Attention Deficit/Hyperactivity Disorder

ObjectiveAttention Deficit/Hyperactivity Disorder (ADHD) negatively affects social functioning; however, its neurological underpinnings remain unclear. Altered Default Mode Network (DMN) connectivity may contribute to social dysfunction in ADHD. We investigated whether DMN's dynamic functional connectivity (dFC) alterations were associated with social dysfunction in individuals with ADHD.MethodsResting-state fMRI was used to examine DMN subsystems (dorsal medial prefrontal cortex (dMPFC), medial temporal lobe (MTL)) and the midline core in 40 male ADHD patients (7-10 years) and 45 healthy controls (HCs). Connectivity correlations with symptoms and demographic data were assessed. Group-based analyses compared rsFC between groups with two-sample t-tests and post-hoc analyses.ResultsSocial dysfunction in ADHD patients was related to reduced DMN connectivity, specifically in the MTL subsystem and the midline core. ADHD patients showed decreased dFC between parahippocampal cortex (PHC) and left superior frontal gyrus, and between ventral medial prefrontal cortex (vMPFC) and right middle frontal gyrus compared to HCs (MTL subsystem). Additionally, decreased dFC between posterior cingulate cortex (PCC), anterior medial prefrontal cortex (aMPFC), and right angular gyrus (midline core) was observed in ADHD patients relative to HCs. No abnormal connectivity was found within the dMPFC.ConclusionPreliminary findings suggest that DMN connectional abnormalities may contribute to social dysfunction in ADHD, providing insights into the disorder's neurobiology and pathophysiology.     

The contribution of the cingulate cortex: treating depressive symptoms in first-episode drug naïve schizophrenia

BackgroundOur previous study has shown the cingulate cortex abnormalities in first-episode drug naïve (FEDN) schizophrenia patients with comorbid depressive symptoms. However, it remains largely unknown whether antipsychotics may induce morphometric change in cingulate cortex and its relationship with depressive symptoms. The purpose of this study was to further clarify the important role of cingulate cortex in the treatment on depressive symptoms in FEDN schizophrenia patients.MethodIn this study, 42 FEDN schizophrenia patients were assigned into depressed patients group (DP, n = 24) and non-depressed patients group (NDP, n = 18) measured by the 24-item Hamilton Depression Rating Scale (HAMD). Clinical assessments and anatomical images were obtained from all patients before and after 12-week treatment with risperidone.ResultsAlthough risperidone alleviated psychotic symptoms in all patients, depressive symptoms were decreased only in DP. Significant group by time interaction effects were found in the right rostral anterior cingulate cortex (rACC) and other subcortical regions in the left hemisphere. After risperidone treatment, the right rACC were increased in DP. Further, the increasing volume of right rACC was negatively associated with improvement in depressive symptoms.ConclusionThese findings suggested that the abnormality of the rACC is the typical characteristics in schizophrenia with depressive symptoms. It's likely key region contributing to the neural mechanisms underlying the effects of risperidone treatment on depressive symptoms in schizophrenia.     

The relationship of diabetes knowledge to regimen compliance and metabolic control during pregnancy

Abstract

The relationship of diabetes knowledge to regimen compliance and metabolic control was examined in a sample of pregnant women with preexisting insulin-dependent and noninsulin-dependent diabetes mellitus (N = 27) and women who developed gestational diabetes during pregnancy (N = 45). Subjects completed self-report measures of diabetes knowledge and compliance with their diabetic regimen and blood glucose levels were monitored. Knowledge was positively, although modestly, related to dietary compliance, compliance with insulin administration and insulin reaction management recommendations, as well as fasting blood glucose levels. Findings suggest that among pregnant women, efforts to increase knowledge of diabetes specific to pregnancy may result in some improvement in selected aspects of the diabetic regimen.     

Modulation of brain oscillations during fundamental visuo-spatial processing: A comparison between female collegiate badminton players and sedentary controls

ObjectivesThe present study aimed to investigate the difference in fundamental cognitive processing and neural oscillations between badminton players and sedentary controls.DesignA cross-sectional design was adopted to address this issue.MethodsWe compared time-frequency electroencephalographic (EEG) activity from collegiate female badminton players (n = 12, aged 20.58 ± 2.75 years) and age-and gender-matched sedentary non-athletic controls (n = 13, aged 19.08 ± 2.10 years) when they performed a task that involves visuo-spatial attention and working memory.ResultsWe observed that players responded faster than controls on the task without suffering any increase in error responses. Correspondingly, the players, relative to controls, exhibited higher task-related modulations in beta power in the attention condition as well as in theta and beta power in the working memory condition. Notably, the behavior-EEG correlations revealed that better attention performance is associated with lower beta power, while greater working memory is related to higher theta power.ConclusionsOur results shed light on the mechanisms of athletic superiority in fundamental cognitive functioning: the higher theta synchronization points to a greater engagement of attention, whereas the higher beta desynchronization supports the contribution of processing speed (or motor-related processing) to better performance in athletes. This study extends current understanding by suggesting that enhanced neurocognitive function seen in athletes may transfer to fundamental tasks, giving insight into the generalizability of sport experience to neurocognitive functioning.     

Mental fatigue,anticipated effort,and subjective valuations of exercising predict choice to exercise or not: A mixed-methods study

ObjectivesThis study examined the effects of mental fatigue on people's decisions to engage in an acute bout of exercise quantitatively, through a sequentially mediated pathway consisting of perceived effort and benefit vs. cost valuations and qualitatively, using exit interviews to survey the conscious reasoning behind participants' choices.DesignMixed methods, randomized, experimenter blind to group.MethodParticipants (N = 84, M_age = 19.07 ± 1.86 years) completed either a high cognitive demand (incongruent Stroop) task or low cognitive demand (documentary viewing) task for 12 min. Before and after the cognitive task, participants rated their anticipated effort and subjective evaluations (benefits and costs) of engaging in a 20-min moderate-to-vigorous intensity exercise task. After completing the latter ratings, participants chose between the exercise task or a non-exercise task (seated “free time” and use of smartphone or computer). Participants were led to believe they would actually engage in the task; however, once their choice was made, they were not required to complete the task but were invited to complete a semi-structured interview to probe the reasoning behind their choice.ResultsSerial mediation analyses revealed a significant indirect effect from mental fatigue to choice through perceived effort and benefit vs. cost valuations (95% C.I. = −0.01 to −0.0004). Qualitative data, organized by categories based on group/choice pairings, yielded twelve unique codes explaining how the cognitive tasks affected choice.ConclusionsResults demonstrate mental fatigue alters decision-making through a sequentially mediated process including subjective perceptions of effort, benefits, and costs. Interview responses also highlight the individual-level consequences of completing cognitively demanding and non-demanding tasks on effort-based decision-making. Future research should explore additional feeling states as they relate to people's choices to engage in exercise or sedentary behaviors.     

Development and initial validity of the Exercise-Related Cognitive Errors Questionnaire

ObjectiveCognitive errors (CEs) reflect individuals' biased evaluations of context-relevant information. In the exercise domain, a valid form of exercise CE assessment is needed. The Exercise-related Cognitive Errors Questionnaire (E-CEQ) was developed to determine to what extent adults make cognitive errors regarding exercise decisions. The purpose of this study was to develop and provide initial validity evidence for the E-CEQ.DesignThe current study used an online self-report survey.MethodFirst, 24 initial vignettes representing 6 CEs were created and content validated. Second, data from 364 adults (M_age = 29.1, SD_age = 11.6; 81.3% female) was gathered to examine the E-CEQ's factor structure. Finally, data from the 364 participants was used to examine aspects of criterion-related validity.ResultsA 16-item, three-factor model was retained as the final E-CEQ factor structure and had good psychometric properties (χ² = 164.35, df = 75, p < .001; RMSEA = .057; CFI = .947; TLI = .915). Evidence of the questionnaire's predictive utility is provided. For example, exercise CEs were negatively related to exercise and accounted for 4.9% of additional variance beyond the contribution of past exercise in predicting exercise intention.ConclusionsThe steps taken to examine different forms of validity helped provide a platform from which to continue (a) to study biases linked to cognitive errors and (b) the E-CEQ validation process through ongoing investigation.     

When is narcissism associated with low empathy? A meta-analytic review

Narcissism is commonly associated with low empathy, but empirical studies have used diverse methods, yielding mixed findings. The present meta-analysis examined the overall magnitude of the association between grandiose and vulnerable narcissism and affective and cognitive empathy (N = 32200). Grandiose narcissism was significantly negatively associated with self-reported cognitive (r = −0.085) and affective (r = −0.145) empathy. When empathy was measured behaviourally, grandiose narcissism was significantly associated only with affective empathy (r = −0.251) but not cognitive empathy (r = −0.052). Vulnerable narcissism was significantly negatively associated with self-reported cognitive and affective empathy (r = −0.179 and r = −0.105 respectively). The association between vulnerable narcissism and cognitive empathy measured behaviourally was not significant (r = −0.069). The association between narcissism and empathy is nuanced and depends on various conceptual and methodological factors.     

Effect of different residential settings on gait kinematic parameters in older adults with cognitive impairment

ObjectiveTo compare the parameters of gait kinematics of older adults with cognitive impairment who live in community dwellings or those living or spending most of the time in non-family environment settings.MethodsThe sample was composed of 33 older adults of both sexes with cognitive impairment. Participants were separated into three groups: a community-dwelling older adult group comprised of 11 subjects; a semi-institutionalized older adult group comprised of 10 older adults attended in a geriatric daycare institution; and an institutionalized older adult group comprised of 12 older adults living in long-term institutions. Gait kinematics were recorded by pressure sensors (footswitches). Fifty gait cycles at self-selected pace were analyzed to obtain: gait speed, stride length, stance, swing, and stride time. The variability of these parameters was also analyzed.ResultsMANCOVA identified the main effect of groups (p < 0.001). Gait speed of older adults living in long-term institutions and older adults attended in geriatric daycare institutions was slower than community-living older adults (p < 0.001 and p = 0.04, respectively). Swing and stride time variability was higher in older adults living in long-term institutions (p = 0.003 and p = 0.001) and in older adults attended in geriatric daycare institutions (p = 0.02 and p = 0.001) than in community-dwelling older adults.ConclusionThe most important finding was that older adults with cognitive impairment who need non-family residential setting care had higher gait kinematics abnormalities, which may increase the risk of falls, compared to those who live in the community.     

Effects of motor-cognitive coordination training and cardiovascular training on motor coordination and cognitive functions

ObjectivesNumerous recent studies showed that physical training can enhance cognitive abilities, such as attention, spatial ability, memory performance, and executive functions. However, most of these studies focused on the efficiency of cardiovascular training, whereas evidence for combined motor-cognitive training emphasizing coordination abilities is scarce. Therefore, the aim of the present study was to investigate the effects of motor-cognitive coordination training and moderate cardiovascular training on cognitive functions and to test whether these effects were related to participant's fitness level.Design and methodWe tested 50 physically active (mean age = 23.5 years, SD = 3.2) and 56 sedentary participants (mean age = 23.4 years, SD = 3.2) in a pretest-training-posttest design with 12 sessions of moderate cardiovascular training (≈60% HRmax) or motor-cognitive coordination training. The training groups were compared to a passive control group. At pretest and posttest, participants performed an untrained motor-cognitive coordination task, measures of executive control (cognitive flexibility, inhibition, working memory), spatial ability, and fluid intelligence.Results and conclusionsWe found improved coordination abilities in the coordination training group, but no transfer of training to cognitive measures in physically active participants. However, sedentary participants showed larger improvements in terms of inhibition in the coordination training group compared to the remaining groups, while the cardiovascular training group improved in cognitive flexibility compared to the remaining groups. In sum, there are positive but differential effects of cardiovascular training and coordination training on cognitive performance in sedentary young participants, suggesting that coordination training may be a useful intervention especially for individuals that cannot perform cardiovascular training.     

Investigating the acute effect of an aerobic dance exercise program on neuro-cognitive function in the elderly

ObjectiveThe present study investigated the types of aerobic dance programs that positively impact cognition, such as executive function, in elderly people.DesignRandomized controlled trial.MethodThe study compared the effects of acute aerobic dance exercise on cognitive performance using two 40-min aerobic dance programs. Thirty-four elderly participants, aged 65–75 years, were randomly assigned into either free (N = 17) or combination (N = 17) style workout groups. The free style (FR) workout consisted of several patterns of movement, while the combination style (CB) workout consisted of similar patterns of movement to FR, but the patterns were joined to form a long choreographic routine. Both dance programs were controlled to be the same in exercise intensity, approximately 40% heart rate reserve. Reaction time and correct rates were measured using a task-switching reaction time test to evaluate executive cognitive performance immediately before and after the 40-min dance exercise.ResultsA two-way (dance program × pre-post dance exercise) repeated-measures analysis of variance for switch reaction time increase (switch cost) demonstrated a significant interaction (p = .006), showing that the switch cost in the CB group became smaller after the dance exercise than before (p = .009).ConclusionThe results suggest that the executive cognitive network was facilitated in a CB dance workout that has a dual-task nature and induces movement (task) interference with unexpected movement changes.     

Women's exercise identity increases after a 16-week exercise RCT and is linked to behavior maintenance at follow-up

BackgroundRegular exercise is critical for disease prevention, but adherence to public health guidelines is poor. Exercise identity is purported to be associated with exercise behavior maintenance, but the extant literature is largely cross-sectional and of low/modest quality.PurposeTo examine change in exercise identity after completion of a supervised exercise intervention, as well as associations between change in exercise identity and exercise maintenance at 6-months follow-up.MethodsN = 276 insufficiently physically active women were randomized to a 16-week, supervised exercise training intervention with 4 conditions fully crossed on intensity (vigorous/moderate) and duration (long/short). Exercise identity was measured pre- and post-intervention and assessments of exercise motivation and behavior frequency were collected at 6-months post-intervention follow-up.ResultsOn average, participants experienced a statistically significant change in exercise identity over the course of the intervention, t (128) = 7.94, p < .001, but identity change scores did not differ across training conditions, p = .91. Identity change was significantly positively related to changes in other theory-informed, motivation-based determinants of exercise, and predicted an additional 16.17 min of exercise per week, on average, at follow-up, b = 16.76, t (103) = 2.30, p = .023.ConclusionsParticipants experienced increased self-identification with exercise after 16-weeks of training, but training volume did not influence the amount of identity change. As expected, greater change in exercise identity was associated with higher levels of exercise behavior at 6-months post-intervention follow-up (ClinicalTrials.gov number NCT02032628 ).     

Proneness for exercise,cognitive and psychophysiological consequences of action observation

ObjectivesPhysical exercise has benefits that go beyond health and well-being, namely in cognitive, motor and psychophysiological areas. The discovery of a shared neural network between action observation and execution (Action-Observation Network) led us to hypothesize that watching human motor action might improve cognitive and motor aspects of performance and proneness for exercise.Design/MethodsSixty participants viewed a Motor (M) (n = 30) or a Non-Motor (NM) (n = 30) movie with strong or weak content of motoric features of human action, respectively. Performance in d2 Attention test, Fitts' Motor task, and a Proneness for Exercise Visual Analog Scale was assessed before and after movie visualization, in a cross-sectional study. Psychophysiological measures were recorded throughout the experiment.ResultsOur results demonstrate an increase in proneness for exercise, and greater improvement in attention-related cognitive aspects in the M group. The aforementioned benefits of action observation did not modulate motor performance. A mental effort deployment was associated to the decrease in heart rate variability after visualization of the NM movie. This was not conducive to attention channeling on task performance. Conversely, M movie observation seemed to be associated to a cognitive load release, affording attention deployment for the resolution of the subsequent tasks.ConclusionsIt seems that some benefits associated to physical practice can result from the mere visualization of movies with human motor action content. These are the improvement in attention-related cognitive skills associated to psychophysiological changes that support a disengagement from mental effort. Crucially, the observation of exercise behavior seems to be a key factor for exercise adherence.     

The effects of pain and a secondary task on postural sway during standing

BackgroundPain impairs available cognitive resources and somatosensory information, but its effects on postural control during standing are inconclusive. The aim of this study was to investigate whether postural sway is affected by the presence of pain and a secondary task during standing.MethodsSixteen healthy subjects stood as quiet as possible at a tandem stance for 30s on a force platform at different conditions regarding the presence of pain and a secondary task. Subjects received painful stimulations on the right upper arm or lower leg according to a relative pain threshold [pain 7 out 10 on a Visual Analog Scale (VAS) - 0 representing “no pain” and 10 “worst pain imaginable”] using a computer pressurized cuff. The secondary task consisted of pointing to a target using a head-mounted laser-pointer as visual feedback. Center of Pressure (COP) sway area, velocity, mean frequency and sample entropy were calculated from force platform measures.FindingsCompared to no painful condition, pain intensity (leg: VAS = 7; arm VAS = 7.4) increased following cuff pressure conditions (P < .01). Pain at the leg decreased COP area (P < .05), increased COP velocity (P < .05), mean frequency (P < .05) and sample entropy (P < .05) compared with baseline condition regardless the completion of the secondary task. During condition with pain at the leg, completion of the secondary task reduced COP velocity (P < .001) compared with condition without secondary task.InterpretationPain in the arm did not affect postural sway. Rather, postural adaptations seem dependent on the location of pain as pain in the lower leg affected postural sway. The completion of a secondary task affected postural sway measurements and reduced the effect of leg pain on postural sway. Future treatment interventions could benefit from dual-task paradigm during balance training aiming to improve postural control in patients suffering from chronic pain.     

Cognitive flexibility and response inhibition in patients with Obsessive-Compulsive Disorder and Generalized Anxiety Disorder

Background/ObjectiveThe main aim of this study was to analyze differences in inhibition and cognitive flexibility, taking into account some variables that may influence results (non verbal reasoning, depression, anxiety, intolerance of uncertainty, comorbidity, medication consumption).MethodThe participants were 95 adults aged 17-61 years old (M = 33.48, SD = 11.13), primary (most severe) Generalized Anxiety Disorder or Obsessive-Compulsive Disorder and a healthy control group. Neuropsychological neasures were completed using computerized Wisconsin Card Sorting Test, Stroop Color Word Test and Go/NoGo Task.ResultsClinical groups presented worse results in cognitive flexibility to the control group. The obsessive-compulsive group showed worse scores in flexibility than the generalized anxiety group, once non-verbal reasoning and tolerance to uncertainty were controlled. Comorbidity and medication use did not affect results in the obsessive compulsive group but did however influence the generalized anxiety group.ConclusionsCognitive flexibility could be included treatment in the treatment of obsessive-compulsive disorder and generalized anxiety disorder.     

Self-control exertion and glucose supplementation prior to endurance performance

ObjectivesCompletion of a task requiring self-control may negatively impact on subsequent self-regulatory efforts. This study explored a) whether this effect occurs during a well-practiced endurance task, b) the potential for glucose supplementation to moderate this effect, and c) whether this effect differed over time.MethodFourteen trained cyclists completed four simulated 16 km time trials on an electromagnetically braked cycle ergometer. Prior to each time trial, participants completed a congruent Stroop task or an incongruent Stroop task that required self-control. They also received either a glucose-based drink or placebo. Participants' performance time and heart rate were recorded throughout the time trials.ResultsMultilevel growth curve analysis revealed a significant three-way interaction between self-control, glucose, and time (b = −0.91; p = 0.02). When participants did not exert self-control (congruent Stroop) or consume glucose (placebo drink) they were slowest during the early stages of the time trial but quickest over the full distance. No differences were found in heart rate across the four conditions.ConclusionsFindings suggest that pacing may explain why self-control exertion interferes with endurance performance. Moreover, the debate revolving around depletion of self-control must consider that any observed effects may be dependent on the timing of performance inspection.