ADHD儿童的选择性抑制

采用较传统停止信号任务更为精确的选择性停止信号任务,探索ADHD的选择性抑制缺陷的机制。结果发现,ADHD儿童在选择性停止信号任务上,抑制失败的比率明显高于正常儿童,但是其执行加工速度和抑制加工速度与正常儿童没有差异,另外,ADHD儿童表现出了更大的反应变异性。研究认为,ADHD在选择性停止信号任务上的抑制缺陷并非由于抑制加工速度过慢所导致,而是由于其不能很好地维持最佳的激活状态所导致,状态调节理论更能反映ADHD的本质。     

Emotional Impulsivity in Children with ADHD Associated with Comorbid—Not ADHD—Symptomatology

Children with ADHD often demonstrate sudden and intense shifts in both positive and negative affect. This study examined the role of diagnostic status on emotional impulsivity in children utilizing ecological momentary assessment (EMA). Parents of 64 8–12 year old children (15 ADHD-only; 27 ADHD-comorbid; 22 control) completed a diagnostic structured interview and then an EMA protocol, rating the child’s affect thrice daily for 28 days. Analysis of covariance (ANCOVA) suggested that children with ADHD and a comorbid disorder demonstrated significantly more EMA-derived emotional impulsivity than children with ADHD only and control children. No difference was found between children with ADHD only and control children. This study suggested that children with ADHD demonstrate significantly higher levels of emotional impulsivity than control children only in the presence of a comorbid disorder.     

Is attention impaired in ADHD?

Explanations of Attention Deficit Hyperactivity Disorder (ADHD) in terms of a weakness in Executive Function (EF) or related concepts, such as inhibition, are briefly reviewed. Some alternative views are considered, in particular a proposal by Manly and others that ADHD is a weakness primarily of sustained attention (plus control of attention), but not of selective attention, as measured by the Test of Everyday Attention in Children (TEA-Ch; Manly et al., 2001). The underlying structure of the TEA-Ch is analysed and it is concluded that the distinction between selective attention, sustained attention, and control of attention in this battery is not well-founded. Furthermore, evidence from studies by Wilding and others, from visual search tasks similar to those employed by Manly et al. to measure selective attention, demonstrates that, while unimpaired- and impaired-attention groups do not differ in speed of performance on such tasks (the measure employed in the TEA-Ch), they do differ reliably in accuracy. Available evidence from other visual search tasks comparing such groups is reviewed and found to be inconsistent. An attempt is made to resolve the inconsistencies and it is suggested that search tasks including demands that engage EF processes are more likely to demonstrate differences between these groups. It is concluded therefore that the most plausible explanation at present of impaired attention is in terms of weaknesses in EF. Suggestions for improving the precision and detail of this type of explanation are offered.     

Is ADHD a disinhibitory disorder?

Attention deficit hyperactivity disorder (ADHD) is widely theorized to stem from dysfunctional inhibitory processes. However, the definition of inhibition is imprecisely distinguished across theories. To clarify the evidence for this conception, the author relies on a heuristic distinction between inhibition that is under executive control and inhibition that is under motivational control (anxiety or fear). It is argued that ADHD is unlikely to be due to a motivational inhibitory control deficit, although suggestions are made for additional studies that could overturn that conclusion. Evidence for a deficit in an executive motor inhibition process for the ADHD combined type is more compelling but is not equally strong for all forms of executive inhibitory control. Remaining issues include specificity to ADHD, whether inhibitory problems are primary or secondary in causing ADHD, role of comorbid anxiety and conduct disorder, and functional deficits in the inattentive ADHD subtype.     

Is the Association of ADHD with Socio-Economic Disadvantage Explained by Child Comorbid Externalizing Problems or Parent ADHD?

It has been unclear whether an associations of child ADHD with socio-economic disadvantage (SES) could be accounted for by (a) parental ADHD explaining both low SES and child ADHD, and/or (b) the joint overlap of ODD or CD with low SES and ADHD. Study 1 used a community-recruited case-control sample with detailed evaluation of SES indicators, child ADHD, child externalizing, and parent ADHD symptoms (n = 931 children, 521 ADHD, 577 boys, 354 girls) in a path modeling analysis with latent variables. Study 2 evaluated ADHD and externalizing behavior in a regression model using a poverty index for SES, in 70,927 children (48.2% female) aged 5–17 years from the US 2011–2012 National Survey of Children’s Health (NSCH). In Study 1, lower SES was related to the ADHD latent variable, β = ?.18, p < .001; 95%CI [?.25,-.12]. This effect held when parent ADHD and child ODD and CD were in the model, β = ?.11, p < .01, 95% CI [?.09,-.03], equivalent to OR = 1.50, 95% CI[1.12–2.04]). In Study 2, these results replicated. Adjusting only for age and sex, children from families who were below 200% of the federal poverty line were more likely to have moderate or severe ADHD than no ADHD, versus children above that line, OR = 2.13, 95% CI[1.79,2.54], p < .001. The effect held after adjusting for disruptive/externalizing problems, OR = 1.61, p < .01, 95%CI [1.32,1.96]. The effect size for comparable models was similar across both studies, lending higher confidence to the results. It is concluded that the SES association with child ADHD is not explained by artifact and requires a mechanistic explanation.     

7-10岁学龄儿童ADHD筛查研究

用SDQ（家长版）对上海10所小学二至四年级学生进行测查,以探求被试的ADHD症状表现,锁定ADHD高风险儿童。结果：（1）男生ADHD得分偏高（p<.01）,但女生在红橙两个级别内的百分数均高于男生;（2）9岁被试的ADHD得分分布最分散,占男生ADHD红色级别的比例最大,在女生ADHD得分中均值最大;（3）红橙两个级别为高风险级别。结论：（1）9岁是ADHD症状表现最严重的年龄;（2）女生具有更高的ADHD风险;（3）ADHD高风险被试晒出率：男生14.4%,女生17.4%。     

正念冥想在ADHD儿童干预中的应用

正念冥想是有意识、非评判地将注意集中于当下经验的方法。近年来,正念冥想作为一种潜在的方法被引进到ADHD儿童干预领域。因为ADHD儿童的特异性,为了增加正念冥想方案对ADHD儿童的适切性,研究者从练习设置、奖励系统、解释方式和家长纳入几个方面对标准的正念减压训练方案做了改编。越来越多的研究证据表明,正念冥想训练能有效地减轻ADHD儿童的核心缺陷、改善其内外化症状和亲子关系。本文通过对已有相关实证研究的分析认为这些积极的影响可能与ADHD儿童的执行功能与去中心化等心理功能的改善有关,而大脑相关区域激活模式的变化和结构的积极改变可能是正念冥想影响ADHD儿童的神经基础。文章也提出已有研究在内容和方法学上的不足及其以后的探究方向。     

Whither causal models in the neuroscience of ADHD?

In this paper we examine the current status of the science of ADHD from a theoretical point of view. While the field has reached the point at which a number of causal models have been proposed, it remains some distance away from demonstrating the viability of such models empirically. We identify a number of existing barriers and make proposals as to the best way for these to be overcome in future studies. These include the need to work across multiple levels of analysis in multidisciplinary teams; the need to recognize the existence of, and then model, causal heterogeneity; the need to integrate environmental and social processes into models of genetic and neurobiological influence; and the need to model developmental processes in a dynamic fashion. Such a model of science, although difficult to achieve, has the potential to provide the sort of framework for programmatic model-based research required if the power and sophistication of new neuroscience technologies are to be effectively exploited.     

钟面画测试及其在ADHD儿童中的研究

钟面画测试被广泛用于研究和测试老年人群中的各种认知缺陷和认知老化,是一种有用的筛选老年痴呆症病人的工具。近年来它也被用于研究正常儿童和ADHD儿童。该文回顾了钟面画测试所涉及的内部认知过程以及影响钟面画测试的各种因素、钟面画测试与执行功能测试之间的相关,并且重点回顾了钟面画测试在正常儿童和ADHD儿童中的研究。由于钟面画测试本身简便、快捷,可以迅速地大规模筛选障碍儿童,在这方面的研究具有重大的实践意义。     

ADHD儿童的病因、诊断及心理干预

ADHD是儿童常见的心理障碍,临床表现为以多动为主的行为问题,其病因包括各种生理因素和社会心理因素,参照SDM-Ⅳ提出具体的儿童多动症诊断标准,对儿童多动症的心理干预提出了支持性心理治疗、行为治疗、运动和游戏治疗以及认知——行为治疗等具体的策略。现在的发展趋势是系统的和整合的心理干预。     

Inhibition,Reinforcement Sensitivity and Temporal Information Processing in ADHD and ADHD+ODD: Evidence of a Separate Entity?

This study compared children with ADHD-only, ADHD+ODD and normal controls (age 8–12) on three key neurocognitive functions: response inhibition, reinforcement sensitivity, and temporal information processing. The goal was twofold: (a) to investigate neurocognitive impairments in children with ADHD-only and children with ADHD+ODD, and (b) to test whether ADHD+ODD is a more severe from of ADHD in terms of neurocognitive performance. In Experiment 1, inhibition abilities were measured using the Stop Task. In Experiment 2, reinforcement sensitivity and temporal information processing abilities were measured using a Timing Task with both a reward and penalty condition. Compared to controls, children with ADHD-only demonstrated impaired inhibitory control, showed more time underestimations, and showed performance deterioration in the face of reward and penalty. Children with ADHD+ODD performed in-between children with ADHD-only and controls in terms of inhibitory controls and the tendency to underestimate time, but were more impaired than controls and children with ADHD-only in terms of timing variability. In the face of reward and penalty children with ADHD+ODD improved their performance compared to a neutral condition, in contrast to children with ADHD-only. In the face of reward, the performance improvement in the ADHD+ODD group was disproportionally larger than that of controls. Taken together the findings suggest that, in terms of neurocognitive functioning, comorbid ADHD+ODD is a substantial different entity than ADHD-only.     

Conners’ continuous performance test (CCPT-II) in children with ADHD,ODD, or a combined ADHD/ODD diagnosis

The current study investigated if results on the Conners’ Continuous Performance Test (CCPT-II) could discriminate between children with ADHD (n = 59), ODD (n = 10), ADHD+ODD (n = 15), and normal controls (n =160), and how the results are associated with and explained by the intellectual function of the child. The sample was derived from the Bergen Child Study (BCS), a longitudinal, ongoing, population-based study of children’s development and mental health. CCPT-II performance did not differentiate between the three diagnostic groups (i.e., ADHD, ODD, and ADHD+ODD). Children with ODD (with or without comorbid ADHD) did not differ from children in the control group on any CCPT-II parameters. Children with ADHD made statistically significant more errors of omissions and showed a more variable response time to targets than the control group. The correlations between CCPT-II measures and IQ were mild to moderate, and there was a statistically significant group difference in IQ: Children with ADHD, and children with ADHD+ODD, obtained lower IQ scores than normal controls. A hierarchical multiple regression analysis showed that IQ, but not diagnostic group status, was significant predictors of CCPT-II performance. CCPT-II performance should be interpreted with caution when assessing ADHD and/or ODD in children.     

Parent–Adolescent Conflict in Teenagers with ADHD and ODD

Eighty-seven male teens (ages 12–18 years) with ADHD/ODD and their parents were compared to 32 male teens and their parents in a community control (CC) group on mother, father, and teen ratings of parent–teen conflict and communication quality, parental self-reports of psychological adjustment, and direct observations of parent–teen problem-solving interactions during a neutral and conflict discussion. Parents and teens in the ADHD/ODD group rated themselves as having significantly more issues involving parent–teen conflict, more anger during these conflict discussions, and more negative communication generally, and used more aggressive conflict tactics with each other than did parents and teens in the CC group. During a neutral discussion, only the ADHD/ODD teens demonstrated more negative behavior. During the conflict discussion, however, the mothers, fathers, and teens in the ADHD/ODD group displayed more negative behavior, and the mothers and teens showed less positive behavior than did participants in the CC group. Differences in conflicts related to sex of parent were evident on only a few measures. Both mother and father self-rated hostility contributed to the level of mother–teen conflict whereas father self-rated hostility and anxiety contributed to father–teen conflict beyond the contribution made by level of teen ODD and ADHD symptoms. Results replicated past studies of mother–child interactions in ADHD/ODD children, extended these results to teens with these disorders, showed that greater conflict also occurs in father–teen interactions, and found that degree of parental hostility, but not ADHD symptoms, further contributed to levels of parent–teen conflict beyond the contribution made by severity of teen ADHD and ODD symptoms.     

Is It ADHD,LD, Depression or Allergies?

Abstract

This article presents a model for understanding the complexity of diagnosing Attention Deficit Hyperactivity Disorder (ADHD). The model uses a continuum of attentional skills to help the reader understand why accurate diagnosis is so important. Issues related to differential determination of attentional problems that may be attributed to learning disabilities, allergies and childhood depression are explored. Specific guidelines to help teachers understand how to judge the appropriateness and comprehensiveness of the diagnostic process are provided.     

Waiting impulsivity: a distinctive feature of ADHD neuropsychology?

Impulsivity is a core feature of attention-deficit hyperactivity disorder (ADHD). It has been conceptualized in a number of different ways. In the current article, we examine how the new concept of “waiting impulsivity”, which refers to premature responding before a scheduled target appears, adds to our understanding of impulsivity in ADHD. Sixty children (8–12 years old; 30 ADHD; 30 typically developing controls) completed the 4-choice serial reaction time task, a measure of waiting impulsivity, alongside tasks measuring inhibitory control and temporal discounting and questionnaires measuring behavioral disorder symptoms, delay aversion, and various aspects of impulsivity. A multiple logistic regression model was used to explore the contribution of the primary task outcomes to predict group membership. Children with ADHD displayed more waiting impulsivity and less inhibitory control; they did not differ in temporal discounting. There was no correlation between waiting impulsivity and inhibitory control. Waiting impulsivity was correlated with parent-reported ratings of hyperactivity/impulsivity, inattention, oppositional defiant disorder (ODD), and conduct disorder (CD) and with self-reported delay aversion ratings. Only waiting impulsivity was a significant predictor of ADHD status. In conclusion, waiting impulsivity is distinct from inhibitory control deficits and predicts ADHD status independently of it. Future research needs to examine the relationship with delay aversion and ODD/CD more thoroughly.