Parental Marital Conflict and Growth in Adolescents’ Externalizing Problems: the Role of Respiratory Sinus Arrhythmia

Previous studies have examined the moderating effect of respiratory sinus arrhythmia (RSA) on the association between marital conflict and externalizing problems, however the findings were inconsistent. One possible reason is that the covariation of internalizing problems in externalizing problems. Therefore, the present study aimed to examine this issue. Participants were 332 Chinese adolescents (54.5% boys) age from 13 to 15 years old. At T1, electrocardiogram monitoring was performed on adolescents during the resting state and stressor tasks (a speech task and a mental arithmetic task) to obtain RSA data. The Chinese version of the Achenbach Youth Self-Report-2001 (YSR-2001) and the Chinese version of the Children’s Perception of Interparental Conflict scale were used to assess adolescents’ externalizing and internalizing problems and their perception of marital conflict, respectively. Adolescents’ problem behaviors were assessed again in the second and third waves of data collection, with a 1-year lag among each wave. The results revealed that the 3- interactions of marital conflict × RSA reactivity in speech task × sex significantly predicted the trajectory of externalizing problems when controlling for internalizing problems from externalizing problems. Specifically, girls with greater RSA suppression to the speech task reported low and stable externalizing problems, however, boys with the same pattern were associated with slightly increased levels of externalizing problems. While, RSA augmentation to the speech task predicted the increase in externalizing problems among both girls and boys in high marital conflict families over time. However, this interaction effects were not significant when not partial out internalizing problems from externalizing problems. The findings highlight the importance of controlling for the covariation of internalizing problems when examining the interaction effects of person and environment on the development of adolescents’ externalizing problems.

     

Associations between respiratory sinus arrhythmia reactivity and internalizing and externalizing symptoms are emotion specific

Internalizing and externalizing disorders are often, though inconsistently in studies of young children, associated with low baseline levels of respiratory sinus arrhythmia (RSA). RSA is thus considered to reflect the capacity for flexible and regulated affective reactivity and a general propensity for psychopathology. However, studies assessing RSA reactivity to emotional challenges tend to report more consistent associations with internalizing than with externalizing disorders, although it is unclear whether this is a function of the type of emotion challenges used. In the present study, we examined whether baseline RSA was associated with internalizing and/or externalizing severity in a sample of 273 young children (ages 5–6) with elevated symptoms of psychopathology. Following motivation-based models of emotion, we also tested whether RSA reactivity during withdrawal-based (fear, sadness) and approach-based (happiness, anger) emotion inductions was differentially associated with internalizing and externalizing symptoms, respectively. Baseline RSA was not associated with externalizing or internalizing symptom severity. However, RSA reactivity to specific emotional challenges was associated differentially with each symptom domain. As expected, internalizing symptom severity was associated with greater RSA withdrawal (increased arousal) during fearful and sad film segments. Conversely, externalizing symptom severity was related to blunted RSA withdrawal during a happy film segment. The use of theoretically derived stimuli may be important in characterizing the nature of the deficits in emotion processing that differentiate the internalizing and externalizing domains of psychopathology.     

Differentiating challenge reactivity from psychomotor activity in studies of children's psychophysiology: considerations for theory and measurement

Current methods of assessing children’s physiological “stress reactivity” may be confounded by psychomotor activity, biasing estimates of the relation between reactivity and health. We examined the joint and independent contributions of psychomotor activity and challenge reactivity during a protocol for 5- and 6-year-old children (N = 338). Measures of parasympathetic reactivity (respiratory sinus arrhythmia [RSA]) and sympathetic reactivity (preejection period [PEP]) were calculated for social, cognitive, sensory, and emotional challenge tasks. Reactivity was calculated relative to both resting and a paired comparison task that accounted for psychomotor activity effects during each challenge. Results indicated that comparison tasks themselves elicited RSA and PEP responses, and reactivity adjusted for psychomotor activity was incongruent with reactivity calculated using rest. Findings demonstrate the importance of accounting for confounding psychomotor activity effects on physiological reactivity.     

Effects of tonic and phasic respiratory sinus arrhythmia on affective stress responses

Adaptive affective responses in the face of environmental challenges require flexible physiological responding. The present study examined the extent to which tonic respiratory sinus arrhythmia (RSA)-a putative marker of regulatory capacity-moderated the association between stress-related changes in RSA (i.e., phasic RSA) and concurrent changes in affect. Ninety-eight healthy, young adults completed ratings of affect during a resting baseline and following the recall of a recent stressor. Tonic RSA moderated the association of phasic RSA with stress-related change in positive affect (PA), such that change in RSA had a positive association with PA for individuals with higher tonic RSA and a negative association for those with lower tonic RSA. Examination of specific aspects of PA indicated that phasic RSA was positively associated with changes in ratings of attentive engagement among individuals with higher tonic RSA. These findings inform our understanding of phasic RSA and support the notion that flexible parasympathetic nervous system functioning is an important component of adaptive stress regulation.     

Parent socialization of coping in emerging adulthood: Moderation by respiratory sinus arrhythmia

This research examined respiratory sinus arrhythmia reactivity (RSAR) as a moderator of the association between parent coping suggestions, or socialization of coping, and youths' responses to stress in emerging adulthood. Emerging adults (N = 156) reported their parents' coping suggestions and their own responses to interpersonal stress; RSAR was monitored as participants completed two laboratory challenges. Results revealed that emerging adults' sensitivity to parental encouragement to engage versus disengage from stress varied as a function of RSAR. Importantly, the RSAR profile (withdrawal vs. augmentation) associated with heightened sensitivity to coping suggestions varied as a function of the nature (interpersonal vs. noninterpersonal) of the laboratory challenge. In some cases, coping suggestions also predicted responses to stress independently of RSAR. This study extends previous work with children and adolescents and provides novel evidence that parasympathetic stress reactivity moderates the effects of parenting in emerging adulthood.     

Examining the Prospective Relationship between Pre-Disaster Respiratory Sinus Arrhythmia and Post-Disaster Posttraumatic Stress Disorder Symptoms in Children

Previous studies have examined the concurrent relationship between posttraumatic stress disorder (PTSD) and a range of psychophysiological variables, including respiratory sinus arrhythmia (RSA). However, there is a lack of research examining the prospective development of trauma symptomatology, and the directionality of the association between RSA level and PTSD has yet to be determined. The current study is the first prospective study to examine whether RSA level and RSA reactivity are risk factors for PTSD symptoms in children. Assessments were conducted both prior to (Time 1) and following (Time 2) a natural disaster (i.e., Hurricane Katrina). Participants were 36 children who were 3–6 years-old during the Time 1 assessment. Structured diagnostic interviews were used to assess PTSD symptoms at both Time 1 and Time 2. RSA level during a neutral stimulus, RSA reactivity to emotional video stimuli (distress, joy, and trauma videos) and RSA reactivity to memory stimuli (remote happy memory, trauma memory, mother’s recall of the trauma memory) were also collected at both time points. Time 1 RSA level during a neutral stimulus was a significant predictor of Time 2 PTSD symptoms (controlling for age, Time 1 PTSD symptoms, Time 2 neutral RSA level), such that lower RSA during a neutral condition was related to higher PTSD symptoms. Also, Time 1 RSA reactivity in response to memory (but not video) stimuli, in the form of relatively less vagal withdrawal, was a significant predictor of more Time 2 PTSD symptoms (controlling for age, Time 1 PTSD symptoms, Time 2 RSA reactivity). This unique prospective study provides evidence for level of RSA and RSA reactivity as pre-existing clinical markers of stress sensitivity that predict psychopathology following a trauma.     

Young Children’s Physiological Reactivity during Memory Recall: Associations with Posttraumatic Stress and Parent Physiological Synchrony

Autonomic reactivity is implicated in stress response and social engagement – both key components of posttraumatic stress disorder (PTSD) – but few studies have examined autonomic reactivity in pediatric samples, and no known studies have examined physiological synchrony among children with PTSD and caregivers. In a sample of 247 young children (94 girls, 153 boys), most (85%) of whom had exposure to trauma and 40% who met criteria for PTSD, we examined children’s patterns of respiratory sinus arrhythmia (RSA) at baseline and in response to a memory recall task, as well as correspondence between parents’ and children’s RSA. Children with PTSD demonstrated significantly higher reactivity than other groups during their recollection of a traumatic memory, but not during other memory tasks. Regarding synchrony, caregivers’ and children’s RSA were more significantly and positively correlated during the trauma recall task among children who had had exposure to a potentially traumatic event but did not meet PTSD criteria, suggesting physiological synchrony may be protective in contexts of trauma. Overall, findings demonstrate physiological reactivity differences among young children with PTSD. While more work is needed to understand the meaning of parent-child physiological synchrony, these data suggest that children’s psychopathology is associated with physiological synchrony processes among young children with exposure to trauma.     

Resting respiratory sinus arrhythmia buffers against rejection sensitivity via emotion control

Emerging evidence suggests that high resting heart rate variability in the respiratory frequency band, or respiratory sinus arrhythmia (RSA) may capture individual differences in the capacity to engage in situationally appropriate regulation of affect and behavior. The authors therefore hypothesized that high RSA may act as a protective factor against difficulties controlling negative affect and hostile behaviors in conflicts with romantic partners in highly rejection-sensitive individuals--a population otherwise vulnerable to these responses. Results were consistent with this hypothesis such that highly rejection-sensitive participants reported less emotion control and more hostility in conflicts only if they were also low in RSA. Furthermore, emotion control mediated the joint effect of rejection-sensitivity and RSA on hostile conflict behavior. These results are consistent with the argument that resting RSA is a marker of flexible responding in the context of highly emotional situations, and further suggest that it may serve as a protective factor particularly in vulnerable populations.     

How language relates to belief,desire, and emotion understanding

Two experiments examined syntax and semantics as correlates of theory-of-mind (ToM). In Experiment 1 children’s language was examined at 3 years of age in relation to ToM at 3, 3.5, 4, and 5.5 years. Semantics predicted unique variance in later belief understanding but not desire understanding. Syntax did not explain unique variance in belief or desire. In Experiment 2 two measures of syntax and a measure of semantics were used with 65 3–5-year-olds. The syntax measures tested children’s understanding of word order and embedded clauses. They were related to false belief, but contrary to some predictions, were also related to emotion recognition. Performance on language control tasks with low syntactic demands correlated equally well with false belief. In both experiments performance on the syntax and semantics tasks was highly inter-correlated. We argue that ToM is related to general language ability rather than syntax or semantics per se.     

Terrorism and cardiovascular responses to acute stress in children.

A number of studies have considered whether background stress affects cardiovascular responses to acute stress tasks. The present study considers the effect of a potent background stressor with a clear onset, namely the terrorist attacks on September 11, 2001. Specifically, the authors investigated differences among 9.5-year-old children tested before (N = 30) and then following (N = 20) the 9/11 attacks. In addition, a majority of these children (N = 37) were retested approximately 1 year later (i.e., before and after 9/11/2002). Children tested directly following 9/11/2001 exhibited significantly greater stroke volume and cardiac output responses to acute stress tasks compared with their responses 1 year later, and this change in reactivity differed significantly from the change in reactivity exhibited by children tested before 9/11/2001 and again 1 year later. These results suggest that a potent background stressor can temporarily heighten some children's cardiovascular responses to subsequent acute stressors.     

Cortical control of sinus arrhythmia in man studied by spectral analysis

Eighteen healthy male volunteers, 21–26 years old, participated in a study intended to detect cortical control of beat-to-beat heart rate variability independent of the effects on breathing and mean heart rate. They were tested while seated and standing relaxed (baseline), and while performing tasks requiring concentrated attention while sitting. The mental concentration elicited a typical cardiorespiratory response manifested by moderate acceleration and shallowing of respiration with a small increase of mean heart rate (HR), a pattern already widely acknowledged as typically associated with concentration. With the aid of a variable tone delivered to the ear as a guide, the subjects were trained to breathe at the same rate without concentrating in order to test the influence of respiration on the concentration pattern. ECG, thermistor pneumogram and ear-lobe photo-plethysmogram were recorded and data reduction was performed on 3 minute or 1 minute data sequences selected for the best steady-state. Statistical treatment was limited to a subgroup of 10 subjects in whom there was no overlapping of the spectra of respiratory and Traube-Hering-Mayer sinus arrhythmia (RSA and THM-SA, respectively). Mental concentration elicited significant depression of both RSA and THM-SA even if the respiratory parameters were kept constant.     

A MATLAB toolbox for correcting within-individual effects of respiration rate and tidal volume on respiratory sinus arrhythmia during variable breathing

Respiratory sinus arrhythmia (RSA) is a common estimator of vagal outflow to the heart, dependent on parasympathetic activity. During variable breathing, both respiration rate and tidal volume contribute substantially to within-individual RSA variance. A respiratory control method allows for within-individual correction of the time-domain index of RSA. rsaToolbox is a set of MATLAB programs for scoring respiration-corrected RSA using measurements of cardiac interbeat intervals, respiratory-cycle times, and tidal volumes, recorded at different paced-breathing frequencies. The within-individual regression of RSA divided by tidal volume upon total respiratory cycle time is then used to estimate the baseline vagal tone for each breath of a given total respiratory-cycle time. During a subsequent analysis, the difference between the observed RSA (divided by the tidal volume at each breath) and the RSA divided by the tidal volume that was predicted by the baseline equation serves as an estimate of changes in vagal tone. rsaToolbox includes a graphical user interface for intuitive handling. Modular implementation of the algorithm also allows for flexible integration within other analytic strategies or for batch processing.     

Interactive effect of long-term mental stress and cardiac stress reactivity on carotid intima-media thickness: the Cardiovascular Risk in Young Finns study

The present study examined the interaction between vital exhaustion and cardiac reactivity and recovery on preclinical atherosclerosis assessed by carotid intima-media thickness (IMT) in young men and women. We measured heart rate (HR), respiratory sinus arrhythmia (RSA), and pre-ejection period (PEP) in response to mental arithmetic and speech tasks. Vital exhaustion and carotid IMT were also measured. Significant associations were observed for men aged 28-37 years, but not for men aged 22-25 years, nor for women in these age groups. It was shown that, among highly exhausted men in the older age group, lower HR reactivity was related to greater IMT. Our results also imply that, among non-exhausted men in this age group, slow HR and RSA recovery after acute stress predicted higher IMT. These results suggest that long-term stress as assessed by vital exhaustion is a risk only if it has resulted in ineffective cardiac stress reactivity. Autonomic imbalance resulting from chronic stress may be the common mechanism linking vital exhaustion and cardiac responsiveness to an increased risk of atherosclerosis.     

Children’s Externalizing and Internalizing Symptoms over Time: The Role of Individual Differences in Patterns of RSA Responding

We examined associations between basal respiratory sinus arrhythmia (RSA) in conjunction with RSA regulation with the hypothesis that their interaction would explain unique variability in children’s prospective adjustment 2 years later. Participants were 176 children (98 girls; 78 boys) in middle childhood. RSA regulation was assessed through social and problem-solving challenges. Parents reported on children’s internalizing and externalizing symptoms. Interactions between RSA baseline and regulation to the social stressor predicted children’s later internalizing symptoms. Interactions between RSA baseline and responding to the problem-solving stressor predicted children’s externalizing symptoms. The highest levels of internalizing symptoms were predicted for children with both lower basal RSA and higher RSA suppression. The highest levels of externalizing symptoms were predicted for children who demonstrated lower basal RSA in conjunction with RSA augmentation. Findings highlight the importance of the contemporaneous consideration of basal RSA and RSA regulation in the prediction of developmental psychopathology symptomology.     

Differential susceptibility and the early development of aggression: interactive effects of respiratory sinus arrhythmia and environmental quality

The purpose of the current study was to predict the development of aggressive behavior from young children's respiratory sinus arrhythmia (RSA) and environmental quality. In a longitudinal sample of 213 children, baseline RSA, RSA suppression in response to a film of crying babies, and a composite measure of environmental quality (incorporating socioeconomic status and marital adjustment) were measured, and parent-reported aggression was assessed from 18 to 54 months of age. Predictions based on biological sensitivity-to-context/differential susceptibility and diathesis-stress models, as well as potential moderation by child sex, were examined. The interaction of baseline RSA with environmental quality predicted the development (slope) and 54-month intercept of mothers' reports of aggression. For girls only, the interaction between baseline RSA and environmental quality predicted the 18-month intercept of fathers' reports. In general, significant negative relations between RSA and aggression were found primarily at high levels of environmental quality. In addition, we found a significant Sex × RSA interaction predicting the slope and 54-month intercept of fathers' reports of aggression, such that RSA was negatively related to aggression for boys but not for girls. Contrary to predictions, no significant main effects or interactions were found for RSA suppression. The results provide mixed but not full support for differential susceptibility theory and provide little support for the diathesis-stress model.     

学前儿童迷走神经活动与情绪反应、情绪调节及冲动性的关系

Porges的多迷走神经理论提出迷走神经活动(vagal activity)与儿童的情绪及社会行为密切联系,已有研究探讨了儿童迷走神经活动与儿童的情绪反应及调节的关系,但研究结论不够清晰,需要进一步研究澄清。本研究选取93名4-6岁学前儿童被试,运用生理测量手段与呼吸性窦性心律不齐(respiratory sinus arrhythmia,RSA)分析的方法,采用父母报告的学前儿童情绪反应强度、情绪调节能力、冲动性为结果变量,进一步探讨儿童迷走神经活动(以基线RSA、RSA撤出、RSA恢复为指标)与情绪反应、情绪调节及冲动性的关系。研究发现:(1)基线RSA与儿童情绪反应强度显著负相关,与儿童情绪调节能力显著正相关,基线RSA是儿童情绪反应强度显著负向预测因子,是儿童情绪调节能力的显著正向预测因子;(2)RSA撤出、RSA恢复性与儿童冲动性显著负相关,是儿童冲动性显著负向预测因子。研究结果支持了Porges的多迷走神经理论,表明迷走神经活动与儿童情绪反应、情绪调节及冲动性密切联系。     

Parasympathetic Regulation and Inhibitory Control Predict the Development of Externalizing Problems in Early Childhood

The current report examined the longitudinal relations between cognitive self-regulation, physiological self-regulation, and externalizing problems. At age 4 (n = 98; 49 girls) and 6 (n = 87; 42 girls), children completed the Day-Night task, which taps the inhibitory control dimension of executive function. During the task, cardiac activity was measured and respiratory sinus arrhythmia (RSA) was derived as an index of parasympathetic activity. Mothers reported on externalizing problems. A cross-lagged path model was used to estimate longitudinal predictions while controlling for stability in all constructs over time. Earlier inhibitory control negatively predicted later externalizing problems, but not vice versa. However, RSA reactivity moderated this link; better inhibitory control predicted fewer externalizing problems only when reactivity to the Day-Night task ranged from mild RSA suppression to RSA augmentation. Externalizing problems at 6 years were highest among preschoolers who augmented RSA but showed poor inhibitory control performance, suggesting that risk for psychopathology may be better delineated by viewing self-regulation from an integrated, multi-system perspective.     

Developmental trajectories of delinquency symptoms in childhood: the role of marital conflict and autonomic nervous system activity

Trajectories of delinquency symptoms across middle and late childhood were examined through latent growth modeling, with a focus on the role of interactions among parental marital conflict, child sex, and multiple indices (baseline, reactivity) of either parasympathetic nervous system activity, indexed by respiratory sinus arrhythmia (RSA), or sympathetic nervous system activity, indexed by skin conductance level (SCL), as predictors of growth. At Time 1, 128 girls and 123 boys (mean age = 8.23 yrs ± 0.73) and their parents participated. The sample comprised 64% European American and 36% African American children. Families participated in second and third waves of data collection with a 1-year lag between each wave. Interactions among marital conflict, sex, baseline RSA, and RSA reactivity from baseline to a frustrating lab task were significant predictors of growth in delinquent behavior from age 8 to age 10, with overall patterns indicating increasing symptoms for boys who lived in high-conflict homes and had an RSA response profile comprising lower RSA during the baseline and RSA augmentation (increase from baseline to the frustrating task). Furthermore, increases in delinquency symptoms over time were observed for children from high-conflict homes and with an SCL profile characterized by higher baseline levels and lower reactivity (less pronounced SCL increases from baseline) to the frustrating task. Findings highlight the importance of contemporaneous assessments of resting and reactivity levels when examining relations among the environment, physiological functioning, and psychopathology. Results are discussed in the context of interactions between biology and environment as relevant to the development of psychopathology.     

Automated respiratory sinus arrhythmia measurement: Demonstration using executive function assessment

Respiratory sinus arrhythmia (RSA) is a quantitative metric that reflects autonomic nervous system regulation and provides a physiological marker of attentional engagement that supports cognitive and affective regulatory processes. RSA can be added to executive function (EF) assessments with minimal participant burden because of the commercial availability of lightweight, wearable electrocardiogram (ECG) sensors. However, the inclusion of RSA data in large data collection efforts has been hindered by the time-intensive processing of RSA. In this study we evaluated the performance of an automated RSA-scoring method in the context of an EF study in preschool-aged children. The absolute differences in RSA across both scoring methods were small (mean RSA differences = –0.02–0.10), with little to no evidence of bias for the automated relative to the hand-scoring approach. Moreover, the relative rank-ordering of RSA across both scoring methods was strong (rs = .96–.99). Reliable changes in RSA from baseline to the EF task were highly similar across both scoring methods (96%–100% absolute agreement; Kappa = .83–1.0). On the basis of these findings, the automated RSA algorithm appears to be a suitable substitute for hand-scoring in the context of EF assessment.     

Differential Effects of Family Stress Exposure and Harsh Parental Discipline on Child Social Competence

Low family socioeconomic status (SES) is a robust risk factor for adverse child outcomes, yet the specific processes that account for this risk are not fully understood. This study examines whether and how variation in two adverse factors, stressful life events and harsh parental discipline, affect children’s social competence within a high-risk environment, and whether some children are more vulnerable to these effects than others. Data were collected from 207 families of kindergarten children at risk for behavioral maladjustment. Children’s physiological regulation (respiratory sinus arrhythmia; RSA) measured during rest was examined as a moderator of risk exposure. Results indicate that both greater exposure to life stress and harsh discipline were correlated with lower social competence. Although children’s resting RSA was not a direct predictor of their social competence, it moderated the association between life stress and social competence. Greater exposure to life stress was more strongly associated with lower social competence among children with lower resting RSA. Higher RSA may help to buffer the effects of stress and facilitate appropriate social development. RSA did not moderate the effects of harsh discipline. This differential pattern of findings suggests that children’s physiological regulation can facilitate an effective response to situational stressors, but may be less efficacious in buffering against stress in the context of the parent-child relationship.