Response to Raymond Lawrence

Pastoral Psychology -     

Motor functions of the basal ganglia

Summary A study of movement disorders such as Parkinson's disease and Huntington's disease can provide an indication of the motor functions of the basal ganglia. Basal-ganglia diseases affect voluntary movement and can cause involuntary movement. Deficits are often manifested during the coordination of fine multi-joint movements (e. g., handwriting). The disturbances of motor control (e.g. akinesia, bradykinesia) caused by basal-ganglia disorders are illustrated. Data suggest that the basal ganglia play an important role in the automatic execution of serially ordered complex movements.     

Impairment of temporal organization of speech in basal ganglia diseases.

Absolute and relative speech timing were examined in patients suffering from Parkinson's, Huntington's, and Wilson's disease. The task was to speak a standard sentence 10 times, first slowly, and then successively faster up to maximum rate. All patient groups had low maximal speech rates and showed decreased variability of speech rate. The duration of pauses between words was the same as in normals and the relative time structure of the test sentence was basically preserved. For comparison, two cases with nonfluent aphasia had even slower speech rates, large increases in pause duration, and major changes in relative speech timing. The results show the same type of alterations of the temporal organization of speech as those characteristic for rapid alternating limb movements in such patients. They support the view that the speech and skeletomotor systems share common neural control modes despite fundamental biomechanical differences. The common denominator between the speech and the skeletomotor disturbances in basal ganglia diseases may be the undamping and slowing of a fast central oscillator.     

Behavioural context and a distributed system: metabolic mapping studies of the basal ganglia.

Behavioural context is known to affect neural activity in the striatum. Responses of single cells increase to rewarding stimuli, or drop out as a bar press or saccade is learned. Networks that can accomplish a unique response to changing contexts are of particular interest to systems neuroscience and were a part of Hebb's interest in perception and learning. An overall map of the striatum that localizes changes related to this remarkable phenomenon of contextual responses contributes to our understanding of anatomical substrates of neural systems that integrate information, and may lead us to new striatal regions to study synaptic mechanisms of learning.     

The differential role of premotor frontal cortex and basal ganglia in motor sequence learning: evidence from focal basal ganglia lesions

There has been a growing interest in the differential role of various neural structures in implicit learning processes. The goal of our study was to clarify how focal lesions restricted to the basal ganglia interfere with different aspects of implicit visuo-motor sequence learning. A version of the Serial Reaction Time Task (SRTT) of Nissen and Bullemer using a 12-trial sequence was administered. A total of 20 subjects with focal basal ganglia lesions caused by ischemic or hemorrhagic infarction and 20 matched control subjects participated in this study. The results indicate that subjects with focal basal ganglia lesions showed unimpaired implicit learning of a 12-item motor sequence. Subjects with basal ganglia lesions, however, had more difficulties improving their general proficiency with the reaction-time task independent of sequence-specific learning. We observed a tendency toward smaller regional volumes in the cerebellum and left pre-supplementary motor area (pre-SMA) of subjects with basal ganglia lesions. Smaller cerebellar and pre-SMA volumes were related to lower implicit learning performance in the lesion group. The size of lesions in the basal ganglia was not related to sequence-specific implicit learning but had a significant influence on subjects' general proficiency for execution of the reaction-time task. We propose that implicit learning is achieved by a distributed network of cortical and subcortical structures. The basal ganglia seem to be responsible for adjusting to the general requirements of a task rather than for learning specific associations between stimuli that might be accomplished by premotor frontal areas and the cerebellum instead.     

Response to Pashler et al. (2016)

Pashler, Rohrer, Abramson, Wolfson, and Harris (2016/this issue) in their critique of Chatterjee, Rose, and Sinha (2013 Chatterjee, P., Rose, R., &; Sinha, J. (2013). Why money meanings matter in decisions to donate time and money. Marketing Letters, 24, 109–118. doi:10.1007/s11002-012-9215-0[Crossref], [Web of Science ®] , [Google Scholar]) data argue that (a) large effect sizes in Study 1 and Study 2 undermine the credibility of the data; (b) in a lexical task that is part of Study 3, a concentration of participants in (5,0) and (0,5) benefit/cost word data points and the similarity of 9 neutral word responses at these points are extremely unlikely; and (c) there are apparent errors in the execution of Study 3. In this response, I examine these issues in detail. A recent review of money prime literature (Vohs, 2015 Vohs, K. (2015). Money priming can change people’s thoughts, feelings, motivations, and behaviors: An update on 10 years of experiments. Journal of Experimental Psychology: General, 144(4), e86–e93. doi:10.1037/xge0000091[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) notes many effect sizes that are as big as or bigger than ours. Although 8 coding errors were discovered in Study 3 data and this particular study has been retracted from that article, as I show in this article, the arguments being put forth by the critics are untenable. For instance, my analysis shows that results hold even without the concentration of (5,0) and (0,5) participants, and I offer statistical simulations to counter critics’ arguments. Regarding the apparent errors in Study 3, I find that removing the target word stems SUPP and CE do not influence findings in any way. I also report findings from MacDonnell and White (2015 MacDonnell, R., &; White, K. (2015). How construals of money versus time impact consumer charitable giving. Journal of Consumer Research, 42, 551–563. doi:10.1093/jcr/ucv042[Crossref] , [Google Scholar]), who replicate the basic finding of Chatterjee et al. in a different context.     

The Relationship of Impulse to Response Timing Error

This paper examines the relationship between response impulse and timing error in 200 msec discrete timing responses over a range of movement velocities and system masses. The results from two experiments showed that variable timing error decreased as both movement velocity and the mass of the system to be moved increased. The variability of force proportional to force (measured either as impulse or peak force) decreased curvilinearly as force output increased. The correlations between each of these parameters and variable timing errors, calculated on a group mean basis, ranged between .91 and .95. The ability to predict the movement time outcome of each individual trial from impulse-related parameters was considerably reduced, although the relationship between the various kinematic and kinetic parameters did strengthen as the movement velocity approached maximum. Collectively, the findings show that size of impulse is related to movement timing error, although it is premature to argue that impulse variability is a causal agent of timing error.     

Response to briscoe (2010)

In an earlier paper my colleagues and I put forth a theory called "perceiving-the-present" that predicts a systematic pattern across a large variety of illusions, and we presented evidence that the systematic pattern exists. Briscoe puts forth arguments against the theory and the existence of the systematic pattern. Here I provide counterarguments to his criticisms of the theory, and I explain why his arguments do not bear on the existence of the systematic pattern.     

Revisiting the constraint attunement hypothesis: reply to Ericsson, Patel, and Kintsch (2000) and Simon and Gobet (2000)

This article is part of an exchange concerning the contributions of the constraint attunement hypothesis (CAH) to the understanding of expertise effects in memory recall. K. A. Ericsson, V. Patel, and W. Kintsch (2000) and H. A. Simon and F. Gobet (2000) claim that the CAH is not novel and that existing theories of this phenomenon do not have the limitations that were attributed to them. In this reply, the CAH is argued to be the only theory of expertise effects in memory recall to adopt the abstraction hierarchy as a theory of the environment, a feature that has important theoretical implications. Also, other theories focus on psychological mechanisms but have not satisfied the burden of scientific proof required of process theories. Progress can be made by integrating the complementary advantages of existing theories into a unified theory that acknowledges the equally important roles of the organism and the environment.     

Effects of focal basal ganglia lesions on timing and force control

Studies of basal ganglia dysfunction in humans have generally involved patients with degenerative disorders, notably Parkinson's disease. In many instances, the performance of these patients is compared to that of patients with focal lesions of other brain structures such as the cerebellum. In the present report, we studied the performance of patients with focal basal ganglia lesions on three fundamental motor tasks. The patients all had suffered unilateral damage in the striatum and were tested in the chronic state. The first task required the participants to tap with their index finger as fast as possible; this test provided a simple assessment of motor competence. Compared to controls, the maximum tapping rate was lower for the patients when tapping with their contralesional limb, although the deficit was not severe. The second and third tasks were designed to assess timing and force control, two functions that have been associated with basal ganglia function. The patients performed similar to controls on both tasks and showed no evidence of impairment when using their contralesional limb compared to their ipsilesional limb. The results indicate that unilateral basal ganglia lesions tend to produce minor motor problems in force control, and fail to support the hypothesized role of the basal ganglia in timing.     

Using TD learning to simulate working memory performance in a model of the prefrontal cortex and basal ganglia

Delayed-response tasks (DRTs) have been used to assess working memory (WM) processes in human and nonhuman animals. Experiments have shown that the basal ganglia (BG) and dorsolateral prefrontal cortex (DLPFC) subserve DRT performance. Here, we report the results of simulation studies of a systems-level model of DRT performance. The model was trained using the temporal difference (TD) algorithm and uses an actor-critic architecture. The matrisomes of the BG represent the actor and the striosomes represent the critic. Unlike existing models, we hypothesize that the BG subserve the selection of both motor- and cognitive-related information in these tasks. We also assume that the learning of both processes is based on reward presentation. A novel feature of the model is the incorporation of delay-active neurons in the matrisomes, in addition to DLPFC. Another novel feature of the model is the subdivision of the matrisomal neurons into segregated winner-take-all (WTA) networks consisting of delay- versus transiently-active units.Our simulation model proposes a new neural mechanism to account for the occurrence of perseverative responses in WM tasks in striatal-, as well as in prefrontal damaged subjects. Simulation results also show that the model both accounts for the phenomenon of time shifting of dopamine phasic signals and the effects of partial reinforcement and reward magnitude on WM performance at both behavioral and neural levels. Our simulation results also found that the TD algorithm can subserve learning in delayed-reversal tasks.     

A self-presentational view of psychotherapy: reply to Hill, Gelso, and Mohr (2000) and to Arkin and Hermann (2000)

The self-presentational view of psychotherapy challenges current assumptions about the benefits of high levels of clients' openness in therapy (A. E. Kelly, 2000). The author responds to questions about whether clients' discretion really is linked to favorable therapy process ratings and outcomes. She also addresses problems that may emerge if readers apply a narrow definition of self-presentation as a form of deliberate manipulation, rather than the intended definition of consciously or unconsciously showing oneself to be a particular kind of person for audiences. A brief review of the evidence on the role of audience feedback in self-concept change is offered, along with suggestions for explaining self-concept change to clients. The author concludes by clarifying and reasserting her suggestion that it is acceptable for clients to reveal the themes as opposed to details of their problems that seem particularly heinous or humiliating.