Diagnostic assessment of cerebrospinal fluid protein in brain and spinal tumors

The cerebrospinal fluid of 69 patients with tumors of the brain and the spine was examined for total protein content, IgG concentration, IgG total protein quotient, and electrophoretic protein pattern. There is no specific finding in the case of the central nervous system. At best characteristic constellations may be established.     

Further notes on differences between percentages

In certain problems dealing with percentage differences, it frequently happens that one is interested in a critical value different from zero rather than in the usual hypothesis of no population difference. Moreover, one may be concerned with differences greater than (or less than) a given magnitude, so that only one tail of the distribution of chance values is used. Tables are here presented to facilitate evaluating results of such problems. One per cent and 5 per cent values can be read from the tables, such values corresponding to the more usual 2 per cent and 10 per cent confidence limits.     

Diagnostic value of aspartate aminotransferase in the cerebrospinal fluid

As datum, the range of aspartate aminotransferase in the cerebrospinal fluid of adults was determined on the basis of 153 fluid samples and compared with the values obtained from 356 neurological patients. A significant increase in enzyme activity was established in respect of CVI, polyneuropathy, acute encephalitis, and SAB. It was possible to eliminate any dependence of the aspartate aminotransferase activity on serum activity, total protein, and cell count. The increase in activity of aspartate aminotransferase in the cerebrospinal fluid is thus identified as an independent pathological fact, and thus it can be incorporated in diagnostic routine more particularly in the diagnosis of CVI disorders.     

Race differences in stress-induced reactivity in young adults

The cardiovascular response to the stress of mental arithmetic was studied in young Black and White adults. Stress-induced reactivity was studied before and following 14 days of oral sodium loading (10 gm NaCl per day). Marginal hypertensives, both Black and White, had greater systolic blood pressure (SBP) levels (p less than 0.001) and greater diastolic blood pressure (DBP) levels (p less than 0.01) in response to stress. Whites had a greater SBP level during mental stress than Blacks (p = 0.008) and greater reactivity (change from baseline; p less than 0.001). The prevalence of sodium sensitivity was greater in Blacks (37.3%) than in Whites (18.4%). Sodium loading did not augment the BP reactivity to the mental stress in any of the racial or BP groups. These data demonstrate racial variation in the cardiovascular response to centrally mediated adrenergic stimuli. The results also suggest that mild BP elevation in Blacks may be regulated through changes in vascular resistance.     

Type A behaviour in pre-school children: Interrater reliability, stability over six months and subcomponents

Type A behaviour was measured in 250 boys and 245 girls (ages 3-7) using a Swedish version of Matthews' Youth Test for Health (MYTH). In addition, speech and voice characteristics (speed, loudness, response latency) were measured. Each child was independently rated by two play group leaders and measurements were repeated after a six month interval. Interrater reliability (first session) was 0.76 for both sexes and did not change with the age of the child. Boys obtained significantly (p less than 0.0001) higher scores than girls. Correlations over the six month period were 0.64 and 0.60 (p less than 0.001) for the two possible combinations of different raters and slightly higher (0.75 and 0.68, p less than 0.001) when the same rater was used. Two components of Type A behaviour were identified from a factor analysis of the data: impatience and competitiveness, and they accounted for 57% of the total variance. As for the total scale, boys obtained significantly higher scores than girls on both subscales. Scores on the competitiveness scale increased systematically with age. Speech and voice characteristics correlated significantly with Type A scores (total Type A behaviour: r = 0.50, using different raters, and 0.71, using the same raters, p less than 0.001) and, once again, boys obtained significantly (p less than 0.001) higher scores than girls. The results are in close agreement with the American findings from the original scale. It was concluded that the scale provides a reliable and valid instrument for measuring Type A or Type A-like behaviours in pre-school children.     

Training family therapy students in conceptual and observation skills relating to the therapeutic alliance: an evaluation

This paper describes a training intervention to develop students' conceptual and observation skills relating to the therapeutic alliance (TA) in family therapy. An evaluation methodology was developed and piloted. The knowledge and observation skills of family therapy students pre‐ and post‐training were assessed in comparison to a non‐intervention group of experienced clinicians. Students' mean scores on the knowledge measure improved significantly from 43 per cent to 74 per cent (p<0.001) and on the observation test from 43 per cent to 65 per cent, although this failed to reach statistical significance (p=0.08). There were no significant changes in the clinicians' scores over the same period. The clinicians' knowledge was higher initially, but the students had caught up after six months. In conclusion, training students in conceptual and observational skills relating to the therapeutic alliance may have a measurable effect. A ‘stepwise’ methodology for demonstrating the relationship between training in TA and outcomes for families is proposed.     

Normal cerebrospinal fluid findings in spinal tumors--an analysis of 503 cases

Till now almost nothing has been published about normal liquor findings in spinal cord tumours. Out of 503 cases there were normal findings of total proteins and cells in 30 cases (6 per cent). A connection with the severity of the compression-syndrome was not evident. Nevertheless liquor examinations are important in diseases of the medulla spinalis. This is especially useful in the differential diagnostical demarcation of inflammable spinal cord diseases, accompanying reactions or bleedings into the spinal channel.     

Family Therapy Training in Clinical Psychology Programs

In a national questionnaire survey of graduate programs offering the Ph.D. or Psy.D. in clinical psychology, the status of family therapy training was examined. With a 79 per cent response rate (102 programs), the study found that 10 per cent of the nationwide faculty identified themselves as primarily family therapy oriented, 32 per cent of the programs had no family-oriented faculty members, 18 per cent of all psychotherapy courses were family therapy courses, and 21 per cent of the schools had no family therapy course. The ratings of the importance of providing students with family therapy training were found to be unrelated to the number of family therapy courses available but positively correlated with the percentage of family therapy courses within the total curriculum.     

Hypnotic pseudomemories,prehypnotic warnings,and the malleability of suggested memories

This study used Orne's nocturnal events paradigm to test the effects of warning highly hypnotizable participants about the possibility of hypnotic false memories. We found that warnings reduced suggestibility but not false memories during hypnosis. Fewer warned participants (12/32, 38 per cent) than unwarned participants (12/16, 75 per cent) accepted the suggestion to hear a noise that awakened them when they were age-regressed to a night of the previous week. However, an analysis of only those persons who accepted the suggestion during hypnosis showed that the warning had no effect on their posthypnotic pseudomemories: among this group, 75 per cent of warned versus 58 per cent of unwarned persons stated immediately after hypnosis that the noise occurred in reality (i.e., reported a pseudomemory). During a final confidential assessment, 58 per cent of the warned participants who had accepted the noise suggestion reported a pseudomemory, versus 50 per cent of the unwarned participants. Comparing pseudomemory rates across all participants, regardless of whether they passed or failed the noise suggestion, 28 per cent of warned participants versus 44 per cent of unwarned participants reported pseudomemories, a nonsignificant difference. Finally, warned and unwarned participants were equally confident in their false memories. © 1998 John Wiley & Sons, Ltd.     

An economical modification of radial immunodiffusion for the determination of immunoglobulins in the cerebrospinal fluid]

In a total of fifty cerebrospinal fluids, such immunoglobulins as IgG, IgA, and IgM were quantitatively determined in a parallel manner on LC partigen plates and on slides (SEVAC set of means of testing). The comparability of the two methods of test proved excellent with good precision. The sensitivity of IgA determination on slides was made higher, the measurability of all precipitates was improved, and the economic advantage increased by cutting the cost of one determination fifteen times.     

Genetic marker findings in systematic and unsystematic schizophrenias

The systematic schizophrenias are marked genetically by a significant surplus of the Gc serum type 1-1 (p less than 0.0005), what can be demonstrated by the separated analysis of the hebephrenias (p less than 0.0005), paraphrenias (p less than 0.01) and catatonias (p less than 0.05) also. Furtheron there is some evidence that the Gc subtype 1F plays a predominant role within the Gc 1-1 excess (p less than 0.01). The unsystematic schizophrenias (periodic catatonias and affective paraphrenias) do not deviate in their Gc distribution from the corresponding control values, but they exhibit contrary to the systematic forms a surplus of the haptoglobin serum group 2-2 like phasic psychoses. The marker findings are discussed with respect to the relevant data of biological psychiatry and biochemical genetics.     

Information processing of letter and word pairs as a function of on and off times

The present study seeks to extend a provisional model of visual information processing with sequential inputs currently under development, employing a computer-based cathode-ray tube display system. Letter and word pairs were presented for 28 different on-off time combinations with on times ranging from 5 msec to 50 msec and off times ranging from 1 msec to 125 msec. The results suggest that both on, off, and total processing times affect per cent correct detections, and that while a gradual increase in per cent correct detections occurs up to about 50 msec of total processing time, a marked discontinuity appears to occur approximately between 50 and 60 msec of total processing time, with per cent correct detections jumping abruptly from about 40% correct detections to about 90% correct detections over a total processing time span of only 10 msec.     

Serum testosterone determination in the antiandrogen therapy of sexual deviations with cyproterone acetate (preliminary report of experiences)

Total testosterone concentrations in the serum of patients treated with antiandrogens were measured by means of an industrially produced radioimmunological testosterone assay kit (VEB S?chsisches Serumwerk Dresden). Antiandrogen therapy using cyproterone acetate (Androcur) leads to a reduction in serum testosterone concentration which is significant at the p less than 0.01 level. The data suggest that testosterone concentrations vary inversely with increasing Androcur dosage; they are around 7 nmol/l at the doses conventionally administered. The testosterone concentrations obtained under depot-Androcur treatment suggest that intervals between injections should be less than 10 days.     

Consumer knowledge and use of country‐of‐origin information at the point of purchase

This paper reports an investigation of American and Canadian consumer acquisition and/or knowledge of the country of origin of products at the time of purchase. Consumer knowledge of the country of origin of purchased products was tested as purchasers left the cash register. If the purchaser knew the country of origin of the product just purchased, they were further questioned to discover the role such knowledge might have played in their choice between alternatives. More than 93 per cent of 1,248 purchasers intercepted at the cash register had not acquired while shopping, or did not know from prior experience, the country of origin of a product they had just purchased. Of the 91 (6.5 per cent) who had acquired or knew the country of origin of a product they had just purchased, only 27 (2.2 per cent of the total) indicated that their knowledge of the product's country of origin possibly might have played a role in their product choice. These findings reveal that the country of origin of products is not an important attribute in the choice processes of the great majority of North American consumers. Confirmation of these findings by replication with less obtrusive and more externally valid measures of consumer acquisition and use of product information prior to purchase is needed. Copyright © 2004 Henry Stewart Publications.     

Developmental changes in application of the majority rule in group decisions

This study examined age-related changes in the child's application of the principle of majority rule in group decisions. Following a problem posed by Moessinger (1981), we enquired whether children routinely apply the majority rule when the majority consists of a shifting (variable) set of members across decisions, and alternate between majority and minority when the majority and minority is fixed, i.e. consists of the same individuals each time. In Geneva, Moessinger found that 8-year-olds failed to discriminate between fixed and shifting majorities, while most 13-year-olds (75 per cent) did so. An altered replication was conducted in Australia modifying Moessinger's procedure to control for extraneous variables such as ‘set’ and the need for variety in choice. It was found that on the task 7 per cent of 8-year-olds, 20 per cent of 10-year-olds, 32 per cent of 12-year-olds, and 39 per cent of 14-year-olds discriminated on a behavioural criterion between fixed and shifting majorities. Ten per cent of 8-year-olds, 40 per cent of 10-year-olds, 52 per cent of 12-year-olds, and 55 per cent of 14-year-olds made the discrimination on Moessinger's cognitive ‘reason’ criterion. The results show that development of the conceptual distinction between fixed and shifting majorities is gradual and continuous.     

Exploring the bio-psycho-social

The United Kingdom Council for Psychotherapy (UKCP) was formed to provide a professional body for all psychotherapists in the UK. It maintains a register of trained practitioners who abide by the ethical standards ratified by UKCP, which includes psychotherapists working in all the modalities recognized by UKCP irrespective of their primary professional training. In the absence of statutory registration, there is no fully representative list of UK psychotherapists, but the UKCP register is probably the nearest thing to it. The UKCP board recognized that a survey of registrants would provide a snapshot of the state of UK psychotherapy, which would be valuable in understanding the contribution of psychotherapists to health services in the UK.

A questionnaire was designed, and sent out to all 4005 practitioners registered by UKCP in December 1997. One thousand three hundred and thirty-one questionnaires were returned, a response rate of 34 per cent. The respondents were representative of all registered psychotherapists in 1998 in those characteristics that are published in the paper register, or that can be inferred from it. The respondents were aged 51 years on average, predominantly white (97 per cent described themselves this way) women (69 per cent) practising in London and the South East of England (55 per cent). All the respondents described themselves as being influenced by psychotherapeutic approaches rooted in psycho-analysis. Ninety-five per cent of respondents had another profession previous to psychotherapy. This was most commonly teaching (27 per cent), social work (22 per cent) or counselling (21 per cent). Only 11 per cent of respondents were psychologists.

The contribution of UKCP registrants to the National Health Service has never previously been estimated. A breakdown of the diaries provided by respondents in this survey suggests that UKCP registrants may contribute as many as 44,760 hours of psychotherapy per week to the British National Health Service and other health sectors. Assuming that a whole-time-equivalent psychotherapist works 37 hours per week, this means that UKCP registrants may provide the equivalent work to health service organizations, both public and private, of more than 1,311 full-time psychotherapists.     

Student Opinion on the Location of Occupational Information on a University Campus

A questionnaire survey revealed student needs, knowledge, and use of occupational information, as well as opinions about the most suitable location of such a resource on the Oregon State University campus. Results indicated that most students did not know where occupational information was available and only a small percentage knew there were occupational files in the Counseling Center and the University library. The great majority (almost 9 out of 10) wanted the University to provide a central occupational library, with most naming the Student Union (40 per cent) or the University library (25 per cent) as the best location. The Counseling Center was mentioned by only 2 per cent of the students.     

The number of active sweat glands (PSI, palmar sweat index) as a psychophysiologic parameter

Two laboratory studies were carried out to assess the behavior of the active palmar sweat glands in both an active and a passive coping situation. Stressor in study I was watching a distressing film, in study II mental arithmetic. Subjects were male students, 17 in experiment I, 20 in experiment II. Both experiments involved a 10-minute baseline phase, a 10-minute stress period, and a follow-up of 10 minutes. PSI was assessed at 90-sec intervals and averaged across phases, as were readings in SCL, SCR, heart rate, diastolic and systolic blood pressure. PSI could be determined in 16 subjects of each study. In both experiments PSI increased significantly from baseline to stress (p less than 0.1%) and decreased from stress to follow-up (p less than 0.1%), and thus proved to be the most sensitive indicator for stress. The interrater reliability for counting the number of active sweat glands was high when the area for evaluation was defined unambiguously. Since the assessment of the PSI does not require a sophisticated technology and is thus also applicable in field research, we suggest giving more consideration to this variable.     

EXAMINING SELECTION UTILITY WHERE COMPETING PREDICTORS DIFFER IN ADVERSE IMPACT

This paper discusses the roles of validity, cut score choice, and adverse impact on selection system utility using data from two concurrent validation studies. We contrast an assessment center and published aptitude test on several metrics, including validity, testing costs, adverse impact, and utility. The assessment center produced slightly lower validity than the aptitude test while costing roughly 10 times as much per candidate. In spite of these advantages for the aptitude test, the assessment center produced so much less adverse impact its operational utility would be higher given cut scores likely to be chosen in this organization. Potential concerns with applying net utility models to this type of situation are discussed in comparison to gross utility models.     

Total surface of temporoparietal intrasylvian cortex: diverging left-right asymmetries

Measurements of the total convoluted surface area of cortex buried in the temporoparietal transition of the Sylvian fissure were performed using "three-dimensional" magnetic resonance morphometry in 10 randomly selected human cadaver brains. The measurements comprised the planum temporale, which covers the superior temporal gyrus posterior to Heschl's first transverse gyrus, and the caudally adjacent walls of the descending and ascending rami of the Sylvian fissure. Also, the total convoluted surface of the planum temporale was compared with its superficially exposed surface as determined by photographical planimetry after brain section, so that the index of cortical folding of the planum temporale could be estimated. The following results were obtained: Cortical folding of the planum temporale did not differ significantly between left and right hemispheres (p greater than .6). The total and the superficially exposed surface of the planum temporale showed significant leftward asymmetry (p less than or equal to .0078). In contrast, the total surface of cortex buried in the caudal segments of the Sylvian fissure posterior to the planum exhibited significant rightward asymmetry (p less than or equal to .016). The combined cortical surface area buried in the whole posterior Sylvian fissure caudal to the first transverse gyrus did not show significant left-right asymmetry (p greater than 0.3). The data suggest divergent lateral asymmetries in the posterior intrasylvian region with excesses of superior temporal cortex in left hemispheres and of supramarginal cortex in right hemispheres.