不同干预方式、不同应激源对血压、心率的影响

探讨不同干预方式、不同应激源对血压、心率影响的差异。被试为本科生48人,采取干预方式、应激源、实验间期的三因素混合实验设计。干预方式为放松训练和预知,应激源为心算和恐怖影片。实验间期包括基线期、干预期、应激期、恢复期。实验的因变量为每个实验间期的血压和心率。结果显示,心算应激引起的血压和心率升高显著高于恐怖影片应激引起的血压和心率的升高;放松训练组和预知组其干预期的血压和心率值都低于基线期;干预方式和应激源在血压和心率两个指标上交互作用不显著。结果表明,与恐怖情绪引起的紧张相比较,智力操作紧张更容易影响血压和心率;放松训练和预知对于对抗应激时血压和心率升高都起到了一定的作用;不同干预方式对于不同性质的应激源作用没有差别。     

外科手术患者的血糖管理

随着糖尿病患患者数的迅速增加,需要接受外科手术治疗的糖尿病患者也越来越多。糖尿病患者的血糖控制与外科手术相互影响,一方面,手术应激可进一步加重糖尿病患者的糖代谢紊乱;另一方面,合并糖尿病使患者发生围手术期并发症甚至死亡的风险大大增加。因此,对糖尿病患者进行完整的术前评估,良好的术前、术中、术后血糖管理是糖尿病患者手术顺利进行、平稳渡过围手术期、改善预后的重要保证。     

糖尿病的治疗现状与糖尿病教育

糖尿病的发病率逐年升高,发展中国家尤为显著,我国作为世界上主要的发展中国家,如何作好糖尿病的预防、治疗和管理工作,已经成为一个重要社会问题。通过对糖尿病的现状及不同治疗模式对糖尿病患者血糖控制的影响等方面加以阐述,以期引起社会关注,加强糖尿病教育,降低糖尿病的发病率,改善糖尿病患者的治疗效果。     

雄性HSF1基因缺陷小鼠的行为改变

为研究HSF1基因缺陷小鼠的行为特征,探索HSF1基因在小鼠行为表现中的作用。选取6~7个月大雄性HSF1基因缺陷小鼠39只及野生型小鼠36只进行情绪性评分、旷场实验、高架十字迷宫实验、简易迷津实验、T-CAT实验、独木桥实验和悬挂实验以观察其情绪性唤醒水平、焦虑水平、探索行为、工作记忆能力和运动能力。结果表明HSF1基因缺陷小鼠的情绪唤醒水平和焦虑水平较低、探索行为减少、T-CAT中转换率较低,提示小鼠的情绪、探索动机和工作记忆受HSF1基因的调控     

糖尿病的治疗现状与糖尿病教育

糖尿病的发病率逐年升高,发展中国家尤为显著,我国作为世界上主要的发展中国家,如何作好糖尿病的预防、治疗和管理工作,已经成为一个重要社会问题.通过对糖尿病的现状及不同治疗模式对糖尿病患者血糖控制的影响等方面加以阐述,以期引起社会关注,加强糖尿病教育,降低糖尿病的发病率,改善糖尿病患者的治疗效果.     

父亲情绪表达与儿童社会适应:气质的调节作用

通过对341名学前儿童进行问卷调查和任务测查,考察了父亲情绪表达、儿童气质与儿童社会适应的关系。结果表明:(1)父亲积极情绪表达对儿童社会能力有正向预测作用;父亲消极情绪表达对儿童社会能力具有负向预测作用,而对外显、内隐行为问题有正向预测作用。(2)儿童的积极情绪性对其外显行为问题与社会能力均有显著正向预测作用;消极情绪性对其社会能力有负向预测作用,而对其外显行为问题有正向预测作用;儿童的努力控制对其外显行为问题有较强地负向预测作用,对其社会能力具有正向预测作用。(3)父亲情绪表达与儿童努力控制、消极情绪性对儿童社会适应有显著交互作用,父亲情绪表达对不同气质特点儿童的社会适应具有不同的预测作用。     

农民工情绪性、弹性和坚韧性特质及其对心理健康的预测作用

采用"中国成年人情绪性量表""中国成年人心理弹性量表""中国成年人坚韧性量表""总体幸福感量表""SCL-10"对559名农民工进行了测试,旨在考察农民工情绪性、坚韧性和弹性特质的负载情况及其对心理健康的预测作用。结果表明,农民工的积极情绪性特质和坚韧性特质的负载量显著高于全国成年人常模,而弹性特质负载量显著低于全国成年人常模;情绪性、坚韧性和弹性特质对于主观幸福感具有显著正向预测作用,而对心理痛苦症状具有显著反向预测作用。     

应激干预对不同行为类型大学生心率血压手指温度的影响

探讨应激干预对心率、血压、手指温度的影响及不同行为类型的差异。被试为河北师范大学本科生72人(A、B型各36人),应激干预为音乐放松、腹式呼吸和静坐休息,实验包括基线期-干预期-应激期-恢复期四个阶段,在观看紧张性影片前进行应激前干预,记录被试的心率、血压、手指温度。结果发现,就缓解应激所产生的交感神经活动增强来说,音乐放松效果较好,腹式呼吸也明显优于自然休息;行为类型（A、B）和应激干预大多表现出来交互作用;个体生理反应的性别差异与生理指标有关,基线值的性别差异较大时,男女生的生理数据不宜混合在一起,基线值相差不大时,可以用相对值（如变化值或变化率）进行统计处理。说明行为类型（A、B）对于应激而言是一种微调变量,在自然休息状态或者低应激水平下作用更明显,应激水平较高时,行为类型的调节作用会显著降低;不同应激干预适用不同行为类型个体     

睡眠时间参数对学前儿童问题行为的影响:消极情绪性的调节作用

本研究以338名学前儿童为被试,采用母亲报告法探究了学前儿童睡眠时间与问题行为之间的关系,以及儿童消极情绪性的调节作用。结果发现：（1）睡眠总时长对儿童内化和外化问题行为的主效应显著,而睡眠总时长与消极情绪性对儿童内化和外化问题行为的交互作用不显著;（2）夜间睡眠比对儿童内化问题行为的主效应显著,对儿童外化问题行为的主效应不显著;夜间睡眠比与消极情绪性对儿童内化问题行为的交互作用显著,即对高消极情绪性的儿童,夜间睡眠比能够显著负向预测其内化问题行为,而对低消极情绪性的儿童,夜间睡眠比对其内化问题行为的预测并不显著;夜间睡眠比与消极情绪性对儿童外化问题行为的交互作用不显著。     

心理行为干预对心血管活动的影响

早在本世纪初．Cannon(1936)等人的研究就已经证明：心理压力和情绪应激可使自主神经系统发生改变,从而导致心率、心输出量、血压等发生明显的变化。情绪应激一方面可以引起自主神经,尤其是交感神经的变化．从而激活交感一肾上髓质系统;另一方面,情绪应激可使下丘脑释放促肾上腺皮质激素释放因子,从而激活垂体一肾上皮质系统。心理实验研究表明,上升的交感一肾上髓质活动或垂体一肾上皮质活动与动脉硬化过程和临床冠心病的许多病理生理状态联系在一起,例如由应激引起的紧张引起交感神经水平升高,这可能是高血压形成的一个重要因素。     

Stress and blood glucose in type II diabetes mellitus

Six adults with non-insulin dependent diabetes mellitus participated in a laboratory procedure to determine the effects of an acute Stressor, mental arithmetic, on blood glucose, cardiovascular, and subjective indices of stress. They then completed 12 days home monitoring of stressful events, subjective stress, and blood glucose. Diet and activity were controlled to evaluate the direct effects of stress on blood glucose in the natural environment. Laboratory results showed significant increases in blood glucose, cardiovascular (HR and SBP), and subjective stress ratings during the mental arithmetic task when compared to a resting condition. Home monitoring data were consistent with the laboratory findings; blood glucose range tended to be greater on high vs low stress days, especially when the difference between high and low stress was greatest. These findings suggest that the laboratory stress induction procedure was externally valid and that in the natural environment, stress has a hyperglycemic effect on blood glucose.     

Effects of combined treatment with vitamins C and E on passive avoidance learning and memory in diabetic rats

Learning and memory deficits occur in diabetes mellitus. Although the pathogenesis of cognitive impairment in diabetes has not been fully elucidated, factors such as metabolic impairments, vascular complications and oxidative stress are thought to play possible roles. Here we investigated the effect of chronic treatment with vitamin C (50 mg/kg, p.o), vitamin E (100 mg/kg, p.o) and both together on passive avoidance learning (PAL) and memory in male Wistar control and diabetic rats. Treatments were begun at the onset of hyperglycemia. Passive avoidance learning was assessed 30 days later. Retention was tested 24 h after training. At the end, animals were weighed and blood samples were drawn for plasma glucose measurement. Diabetes caused impairment in acquisition and retrieval processes of PAL and memory. The combination of vitamin C and E improved learning and memory in controls and reversed learning and memory deficits in diabetic rats. Combined treatment also affected the body weight and plasma glucose level of diabetic treated animals compared to untreated diabetic animals. Hypoglycemic effects and antioxidant properties of the vitamins may be involved in the nootropic effect of such treatment. These results show that combined treatment with vitamins C and E improved PAL and memory of control rats. In addition, combined vitamins administration to rats for 30 days from onset of diabetes alleviated the negative influence of diabetes on learning and memory. Therefore, combined vitamins treatment may provide a new potential alternative for prevention of impaired cognitive functions associated with diabetes and may warrant further clinical study.     

糖尿病与睡眠的相互关系

人一生中有1／3的时间在睡眠中度过,睡眠质量直接关系到一个人的身体健康。睡眠时间过少或过多的人糖尿病患病率大大增加。糖尿病本身的病理、生理特点,严重影响患者的睡眠质量,睡眠质量又可以反过来影响糖尿病患者的血糖水平。有研究显示,糖尿病患者最佳睡眠时间为8小时。同时糖尿病患者中睡眠呼吸暂停综合征（OSAS）患病率高,0SA...     

Dyadic parent-child interaction during early childhood: contributions of parental and child personality traits

Individual differences in personality play a major role for functioning in a multitude of important life domains, including one's interpersonal relationships. The present study examined the effects of parental personality and child temperament traits on dyadic parent-child interaction during early childhood. Participants were a community sample of 145 mothers, 145 fathers, and their 3- to 6-year-old children. Child traits were assessed using standardized laboratory paradigms, parents reported on their own traits, and parent-child interaction was assessed observationally. Parental positive emotionality, negative emotionality, and constraint subtraits were related to parental responsiveness; the number and type of parental bids and the quality of parental responsiveness were also a function of child positive emotionality and effortful control subtraits and, for mothers, child negative emotionality subtraits. Child traits were related to their own interaction behaviors; children higher on positive emotionality subtraits made more social bids, and children higher on effortful control subtraits made more influence attempts and fewer negative bids; child positive emotionality and effortful control subtraits were associated with higher quality child responsiveness. Findings speak to coherence in personality constructs across the life span, with comparable traits measured in adults and early childhood-aged children demonstrating remarkably consistent effects on dyadic interaction behavior.     

Parenting anxiety and stress: does gender play a part at 3 months of age?

In this study, the authors compared 90 pairs of mothers and fathers with respect to aspects of negative emotionality experienced in the early parenting role. Mothers and fathers of 90 healthy 3-month-old infants completed questionnaires pertaining to parenting stress and separation anxiety. Mothers reported significantly higher levels of negative emotionality than did fathers. An interaction effect of parent with child gender on the level of parenting stress was indicated. Mothers of sons reported more stress than did mothers of daughters. The child's gender was not related to the level of separation anxiety expressed by mothers and fathers. The findings suggested that, at 3 months of age, the child's gender plays a role in the parenting experience, but the impact is (a) moderated by the parent's gender and (b) construct-specific (e.g., stress). These findings are in line with a multidetermined model of parenting.     

妊娠期糖尿病管理策略

妊娠期糖尿病(gestational diabetes mellitus,GDM)是指妊娠期发生或首次发现的不同程度的糖代谢异常。未加控制的妊娠期高血糖可对母子产生极大的围产期和远期危害。妊娠后糖代谢发生明显变化妊娠期血糖的管理和控制与非孕期不同。GDM一经确诊,应及时干预,加强母儿监测,控制妊娠期血糖,以降低母儿并发症,改善围生儿结局;产后对母儿严密随访,异常者给予相应处理,以减少或延缓产妇在产后发展为成为2型糖尿病的可能及预防子代发生肥胖、高血压、糖尿病等代谢综合征的发生。     

Type A Behavior and Diabetic Control: Implications of Psychological Reactance for Health Outcomes1

According to laboratory research, Type A coronary-prone individuals are sensitive to threats to their personal control and react to such threats with active and often stressful coping responses. The present investigation tested the prediction that these features of Type A behavior would interfere with blood glucose regulation in insulin-dependent diabetes mellitus patients. Two independent hypotheses were investigated. Because elevated sympathetic arousal, a concomitant of stressful coping, is associated with elevated glucose levels, it was predicted that Type A diabetics experiencing high levels of life stress would display poorest blood glucose control (indexed by Hemoglobin A₁c). The second hypothesis was derived from the observation that Type As are more likely than Type Bs to respond to control threats with reactance in order to restore the perception of control. Given that illness or treatment can reduce personal control, it was predicted that Type A diabetics would be most reactant and, thus, most medically noncompliant. To test these hypotheses, 37 Type 1 diabetics were assessed for Type A behavior, life change, attributional style, desire for control (both within treatment and in general), and specific perceptions of and actions to their diabetes. Type As were more likely than Type Bs to show poor blood glucose control. However, for patients in general, and Type As in particular, blood glucose regulation was not related to life stress. Rather, those Type As who displayed poor glucose control made more extreme self-attributions about the cause of their diabetes, were angrier about it, and felt they should fight it. The implications of these findings for a reactance-Type A model of medical compliance are discussed.     

2型糖尿病一级亲属代谢相关指标分布规律的研究

为了研究2型糖尿病(DM)家系一级亲属的代谢相关指标变化规律,选择55个2型糖尿病家系中糖尿病患者的一级亲属为研究对象,按照糖耐量试验结果分组,比较组间血压、血糖、血脂、C肽、胰岛素等指标。结果显示,2型糖尿病家系一级亲属各组血脂水平的变化差异无显著性,而血糖、胰岛素抵抗等指标差异有显著性。由此得出结论,2型DM家系一级亲属血脂、血糖、血压、胰岛素等指标均有一定程度的异常,且各组间的血糖、血压、胰岛素抵抗等差异显著于血脂水平的变化。     

Perceived stress and diabetes control in adolescents

Studies of diabetes control have traditionally focused on patients' regulation of insulin, diet, and exercise. Although psychosocial stress may also influence blood glucose, researchers have infrequently accounted for the three primary physiological factors when estimating the effects of stress. In addition, few investigators have considered the influence of everyday minor stressors on health outcome. The Tennessee Camp for Diabetic Children provided an opportunity to monitor insulin administration, dietary intake, and exercise levels and to obtain measures of blood glucose and perceived minor stressors. The best index of stress was one in which number and magnitude of negative stressors were combined into a cumulative stress measure. Negative cumulative stress significantly correlated with blood glucose levels after controlling for the effects of insulin, diet, and exercise. In addition, diabetes control tended to be better when adolescents, particularly boys, adjusted well to negative stress. These findings suggest that minor stressors can influence health outcome, but positive and negative stress need to be assessed independently.