Simulating social interaction to address deficits of autistic spectrum disorder in children.

Autistic spectrum disorder (ASD) is diagnosed on the basis of impairment in reciprocal social interaction and language, and rigidity of behavior. This brief paper describes the development of an experimental intervention for preschool children newly diagnosed with ASD. The rationale for this intervention is the hypothesis that failure to attend to social cues in very early life, of itself, may bear a large share of responsibility for core social and communicative deficits. The intervention, therefore, uses eye-tracking to monitor and trigger rewards for attention to facial expression and direction of gaze.     

Pitch perception in children with autistic spectrum disorders

This study investigated the accuracy of musical pitch detection in children with autistic spectrum disorders as compared with typically developing children. Seventeen children on the autistic spectrum (M(age) =9.34, SD(age) =1.12) and 13 typically developing, chronological age-matched children (M(age) =9.13, SD(age) =1.68) took part in the current study. Children were required to listen to four tones, which were paired with four different pictures and asked to learn the combinations. The children were then assessed for their ability to identify the previously learned tones, when they were presented as single tones and when they were embedded in chords and discords. No significant group differences were found. However, after subdividing the clinical group according to their diagnosis of autism or Asperger's syndrome, the results indicated a slightly superior disembedding ability in participants with Asperger's syndrome. The findings are discussed in terms of the weak central coherence concept.     

Unfamiliar face recognition in children with autistic spectrum disorders

We investigated unfamiliar face recognition in low‐functioning children with autistic spectrum disorders (ASD) using a ‘part‐of‐face’ method. This method has not previously been used for unfamiliar faces with this population. The ‘part‐of‐face’ procedure provides measures of both face recognition accuracy and of processing style. We compared the performance of the children with ASD with three control groups: children with developmental delay (DD), typically developing (TD) children matched for verbal cognitive ability and TD children matched for chronological age (CA). Compared to the DD group, the ASD group showed similar processing in recognition accuracy and processing style. Compared to the TD children, the ASD group did not show the same level of accuracy as controls of the same CA, instead showing similar performance to younger TD children. However, as both children with ASD and DD showed the same performance, no ASD‐specific deficit was found. Copyright © 2009 John Wiley & Sons, Ltd.     

Visual perspective taking impairment in children with autistic spectrum disorder

Evidence from typical development and neuroimaging studies suggests that level 2 visual perspective taking - the knowledge that different people may see the same thing differently at the same time - is a mentalising task. Thus, we would expect children with autism, who fail typical mentalising tasks like false belief, to perform poorly on level 2 visual perspective taking as well. However, prior data on this issue are inconclusive. We re-examined this question, testing a group of 23 young autistic children, aged around 8 years with a verbal mental age of around 4 years and three groups of typical children (n = 60) ranging in age from 4 to 8 years on a level 2 visual perspective task and a closely matched mental rotation task. The results demonstrate that autistic children have difficulty with visual perspective taking compared to a task requiring mental rotation, relative to typical children. Furthermore, performance on the level 2 visual perspective taking task correlated with theory of mind performance. These findings resolve discrepancies in previous studies of visual perspective taking in autism, and demonstrate that level 2 visual perspective taking is a mentalising task.     

Learning new faces in typically developing children and children on the autistic spectrum

As faces become familiar, recognition becomes easier but the style of processing also changes. Here, twenty-one typically developing (TD) children and twenty-one children with autism spectrum disorder (ASD) were familiarised with 6 identities over 3 days. Next, they completed a 4-alternative forced-choice matching test in which targets were the 6 familiarised faces and 6 unfamiliar faces. The TD group showed a significant advantage for familiarised faces when matching whole faces and both internal and external facial regions. The ASD group showed similar familiarisation effects for whole and external faces, but not for internal regions. The ASD group was also impaired at matching eyes and mouths of familiarised faces. Results suggest the process of acquiring familiarity with faces differs from ASD and TD children.     

Ambiguous figure perception and theory of mind understanding in children with autistic spectrum disorders

Researchers in early social‐cognition have found that the ability to reverse an ambiguous figure is correlated with success on theory of mind tasks (e.g. Gopnik & Rosati, 2001 ). The present experiment examined children with autistic spectrum disorders (ASD) without mental delay to see whether a similar relationship existed. Ropar, Mitchell, and Ackroyd (2003) demonstrated that children with ASD with mental delay were impaired on theory of mind tasks, but were as likely as mentally delayed controls to generate both interpretations of an ambiguous figure when informed of its ambiguity. The present study replicated this finding on children with ASD without mental delay. However, overall perception of ambiguous figures was different. These children were less likely to spontaneously generate both interpretations of the figure, and more likely to perseverate on a single interpretation than the comparison children. Like Ropar et al., we found no correlation between theory of mind and informed reversals, but spontaneous reversals were correlated with performance on an advanced theory of mind task. These data suggest that reversals of ambiguous figures are linked to higher‐level representational abilities, which might also be involved in social functioning, and impaired in children with ASD.     

Measuring change in psychotherapeutic work with a traumatised child on the autistic spectrum

This paper describes a developmental psychotherapy undertaken with a physically disabled latency boy, with a background of significant developmental deficits and multiple psychological trauma, diagnosed by CAMHS as being on the autistic spectrum. Using an assessment framework following Anna Freud’s conceptualisation of developmental lines, pathology as a deviation from the norm was formulated. Assessments using standard psychological tests were made at the beginning, in the middle, and at the end of his therapy, in order to study the changes in his personality development. Standard assessment findings were also used to portray the fragmentation of the boy’s psyche in a concrete fashion, in order to facilitate his re-integration.     

Classroom treatment of autistic children: II. individualized instruction in a group

This study was designed to assess the feasibility of providing individualized instruction in a classroom of autistic children. In particular, we investigated whether students' unsupervised responding was a variable which would influence the effectiveness of individualized instruction procedures. Initially, one teacher attempted to teach different academic behavior to four autistic children simultaneously. During these sessions the teacher rotated from child to child, providing individualized instructions and reinforcers to each. We found, however, that each child stopped responding whenever the teacher rotated to a different child and, further, no academic progress occurred for any of the children during these sessions. In a multiple baseline design, treatment procedures were then introduced (prompt fading, chaining, and programmed instructional materials) to teach each student to continue working for an extended period of time after each instruction from the teacher. After treatment, sessions of individualized instruction in a group were reintroduced for each child. The results showed that unsupervised responding was an important variable influencing the effectiveness of individualized instruction. Specifically, the data show that (1) unsupervised responding, acquired during treatment, generalized to the group setting; (2) after treatment, each child began to make progress on his assigned tasks; and (3) programming instructional materials in small steps appeared to be necessary in order to ensure the maintenance of unsupervised responding across changes in instructional materials. By the end of this study it was possible for one teacher to simultaneously teach four autistic children — with each child learning at his own rate, on his own task, with minimal supervision from the teacher. It is suggested that the generalizability of these results, to other settings where continuous supervision is difficult, may be an important concern of future research.     

Factors influencing adjustment in the families of autistic children.

This study investigated factors influencing the adjustment of families of 49 autistic children (38 boys, 11 girls) to the stress of raising an autistic child. Analysis indicated that the severity of the child's disorder (stress), mother's social support (resources), and mother's perceived locus of control (perception) were significant factors in family adjustment. In addition, evidence suggested that agency affiliation also was an unexpected, yet important factor.     

The relationship between theory of mind and metaphor: Evidence from children with language impairment and autistic spectrum disorder

Happé (1993) proposed that theory of mind (ToM) understanding was necessary for comprehension of metaphorical expressions. The current study investigated the role of both ToM and language ability in metaphor understanding. Ninety‐four children aged 8–15 years with communication impairments were grouped according to language ability and autistic symptomatology in the first instance, and then according to ToM performance. Their performance on a metaphor task was compared to 34 typically developing age‐matched peers. These analyses showed that only children with language impairment, with or without concurrent autistic features, were impaired on the metaphor task. Furthermore, possession of first‐order ToM skills did not ensure metaphor comprehension. Instead, semantic ability was a stronger predictor of performance on the metaphor task. These results are considered with reference to the view that ToM understanding is necessary for the comprehension of metaphor.     

Evidence for language recoding in autistic, retarded and normal children: a re-examination

In a replication and extension of earlier studies by Hermelin & O'Connor, language recoding abilities in autistic, retarded and normal children matched for mental age and digit span, were compared in a verbal recall task. Random word lists, sentences, and anomalous sentences, eight or 12 items in length (for high and low memory span subgroups) were presented and the number of words recalled from each type of input was scored. All low span children recalled sentences better than random lists with normal children superior to retarded and autistic children and the latter group poorer than the retarded group. Autistic children showed a recency effect with both types of input. There were no group differences amongst high span children and sentences were again better recalled than random lists. In Expt II sentences were better recalled than anomalous sentences, with autistic and retarded children equivalent in performance and poorer than normal children. Although low span autistic children were clearly deficient in recall of sentence material when compared with the two control groups, the effect of conditions showed that they were able to use structure to improve recall. Since high span autistic children did not perform differently from controls it is suggested that results from this kind of study may not be generalizable, and that claims for a specific coding deficit in autistic children need further substantiation.     

II. Genotype-environment interaction in the schizophrenia spectrum: qualitative observations

Previous reports from the Finnish Adoptive Family Study of Schizophrenia have documented significant interplay between genetics (G) and family rearing (E), leading to adoptee outcomes of schizophrenia spectrum disorders. Quantitative evidence for this interplay is significantly enhanced when both high genetic liability and severe environmental dysfunction are present. However, when either genetic liability is low or the rearing environment is healthy, the adoptees appear to be resiliently protected against a pathologic outcome. Nevertheless, exceptions to this pattern do occur. Six qualitative vignettes, together with quantitative measures and categorical diagnoses from the same families, illustrate how multiple methods partially confirm one another and also suggest where further exploration of gene-environment interaction is needed.     

Acquired epileptiform aphasia: a dimensional view of Landau-Kleffner syndrome and the relation to regressive autistic spectrum disorders.

Acquired epileptiform aphasia (AEA) is characterized by deterioration in language in childhood associated with seizures or epileptiform electroencephalographic abnormalities. Despite an extensive literature, discrepancies and contradictions surround its definition and nosological boundaries. This paper reviews current conceptions of AEA and highlights variations in the aphasic disturbance, age of onset, epileptiform EEG abnormalities, temporal course, and long-term outcome. We suggest that AEA, rather than being a discrete entity, is comprised of multiple variants that have in common the features of language regression and epileptiform changes on EEG. Viewed this way, we argue that AEA can be conceptualized on a spectrum with other epileptiform neurocognitive disorders that may share pathophysiological features. The implications of this viewpoint are discussed, with emphasis on parallels between the AEA variants and regressive autistic spectrum disorders.     

A replication of preference displacement research in children with autism spectrum disorder

The purpose of this paper was to replicate previous research on preference displacement with edible and leisure stimuli. In the present study, the experimenters evaluated preference displacement in 25 children with autism spectrum disorder using combined multiple stimulus without replacement preference assessments that consisted of highly preferred edible and leisure stimuli. In addition, the experimenters used a block randomization procedure to evaluate if assessment order influenced displacement outcomes. The experimenters observed patterns of complete displacement by edible stimuli for four participants and complete displacement by leisure stimuli for two participants; assessment order did not influence outcomes. The results and implications are discussed.     

Recent research on the relative efficiency of speaker and listener instruction for children with autism spectrum disorder

The traditional recommendation for sequencing speaker and listener instruction has been to teach listener skills prior to teaching speaker skills. In a review of the research literature prior to 2011, Petursdottir and Carr (2011) concluded that research did not support this recommendation. We reviewed the most recent research on the efficiency of skill acquisition during speaker and listener instruction and found similar results to Petursdottir and Carr. Recommendations for future research and practice are provided.     

The use of structural equation modeling in generative research: Toward the design of a preventive intervention for bereaved children

Describes a generative study of processes which may lead to symptomatology in children who have experienced the death of a parent. Based on existing literature, four putative mediating variables were identified: parental demoralization, family warmth, negative family events, and positive stable family events. Structural equation modeling techniques were used to compare several potential causal models involving these variables. The results were most consistent with a model in which bereavement was not directly related to the child symptomatology, but rather its effects were transmitted through these four mediational mechanisms. The implications of the results of the structural modeling for the design and evaluation of preventive interventions are discussed briefly.     

Neurobehavioral functioning in children with fetal alcohol spectrum disorder.

Neurobehavioral functioning of 50 Canadian children diagnosed with Fetal Alcohol Spectrum Disorder (FASD) was evaluated. The aims of this study were to identify specific areas of weakness in neurobehavioral functioning, to examine whether neurobehavioral functioning was related to various predictor variables, and to determine which measures differentiated between children given a brain score of 2 (possible dysfunction) and 3 (probable dysfunction). Participants displayed difficulties with many aspects of intelligence, memory, executive functioning, and attention. Measures of Full scale and Verbal IQ, as well as memory for faces and numbers differentiated between children with a brain 2 and 3 ranking. An interesting pattern of strengths and weaknesses emerged as well as significant differences related to ethnic background, gender, and age. Aboriginal children and Caucasian children with FASD do not appear to show the same pattern of strengths and weaknesses in neurobehavioral functioning.     

The development of functional and equivalence classes in high-functioning autistic children: the role of naming.

The development of functional and equivalence classes was studied in four high-functioning, preschool-aged autistic children. Initially, all subjects failed to demonstrate match-to-sample relations indicative of stimulus equivalence among two three-member classes of visual stimuli. Then, 2 subjects showed emergence of those relations after they were taught to assign the same name to all members in each class. Next, subjects were taught names for new stimuli outside the match-to-sample format. On subsequent match-to-sample tests, 2 subjects demonstrated untrained conditional relations among the stimuli given a common name. New, unnamed stimuli were then related via match-to-sample training to stimuli from sets of named stimuli. Tests for emergent conditional relations between the new unnamed stimuli and the named stimuli yielded positive results for 1 subject and somewhat mixed results for 3 subjects. Finally, without naming, 2 subjects developed stimulus equivalence among two new three-member classes of visual stimuli. These data suggest that naming may remediate failures to develop untrained conditional relations, some of which are indicative of stimulus equivalence.