Personality Trait Characteristics in Relation to Neuropsychological Dysfunction in Schizophrenia and Depression

Knowledge of the personality trait and psychopathology variables that differentiate neuropsychologically impaired and nonimpaired psychiatric patients has been limited relative to the study of higher cortical functions. This study reports findings from the Milton Clinical Multiaxial Inventory (MCMI) developed by Millon (1982) in a sample of hospitalized schizophrenics and depressives who also received the Luria-Nebraska Neuropsychological Battery. The principal findings indicate that neuropsychological dysfunction may be related to substance abuse, including its underlying personality dimensions, in schizophrenia, but only modest support is indicated for the construct of negative symptoms in schizophrenics with neuropsychological dysfunction. Further, the findings do not support the view that psychosis is a characteristic feature of depressives with impaired neuropsychological performance.     

Peabody Picture Vocabulary Test-Revised and luria-Nebraska Neuropsychological Battery for Children: intercorrelations for normal youngsters

The relationship between scores on the PPVT-R and Luria-Nebraska Neuropsychological Battery for Children was examined utilizing 86 normal children, including 55 females and 31 males from middle-class families. Correlation coefficients were computed between the standard scores obtained on the PPVT-R and the T scores from the summary scales on the Luria-Nebraska. Significant relationships were predicted between the PPVT-R and the Receptive scale on the Luria-Nebraska. Significant but small correlations were found between the PPVT-R and this scale as well as the Intelligence, Visual, Arithmetic, Memory scales on the Luria-Nebraska.     

Emotional disturbances and their interaction with neuropsychological deficits

The interaction and relationships between neuropsychological tests (which are principally oriented to intellectual and cognitive abilities) and tests of personality and emotional status are complex, but nevertheless important in the clinical assessment of brain-damaged persons. Are indications of emotional disturbances to be expected as a direct consequence of brain damage? If so, how can the indications of emotional disturbances be differentiated from results obtained with psychiatrically disturbed (non-brain-damaged) subjects? Some authors have presumed that emotional disturbances, such as depression, acute anxiety, etc., in their own right cause impaired performances on neuropsychological tests, whereas other authors have proposed that brain damage predisposes the individual to demonstrate evidence of emotional disturbances. If emotional disturbances cause impairment on neuropsychological tests, why is it that so many emotionally disturbed persons without brain damage tend to perform normally on neuropsychological tests? This review of relevant publications considers (1) different general approaches to these questions and their implications for neuropsychology, (2) evidence of differential sensitivity to brain damage of neuropsychological and emotional instruments, (3) the sensitivity and specificity of self-assessments and complaints of head-injured subjects, (4) MMPI findings among head-injured subjects and in interaction with neuropsychological measurements, and (5) principles and guidelines that may be of value in clinical application of findings reported in the literature.     

The sensitivity of the Bender-Gestalt Test as a screening instrument for neuropsychological impairment in older adults

We investigated the sensitivity of the Bender (1938) Visual-Motor Gestalt Test (BGT) using the Halstead-Reitan Neuropsychological Battery (HRB) as the criterion for cortical dysfunction. We studied 95 subjects over age 55 who had been diagnosed as having dementia or pseudodementia. Subjects were classified as mild, moderately, or severely impaired on the HRB and as impaired or unimpaired on the BGT. The results indicated that the BGT is less sensitive (36%) than was expected when used on an impaired geriatric population. The data further indicated that false negatives occurred more frequently with the BGT when individuals had mild neuropsychological impairment. Less frequent misclassifications occurred as the severity of impairment on HRB indices increased.     

Influence of Socio-Demographic Factors on SRAVEN Performance

This exploratory study aimed to investigate the influence of specific socio-demographic variables on a computerized test of non-verbal neuropsychological performance. Six hundred and thirty South African first year students were assessed using the University of Pennsylvania Computerized Neuropsychological Test Battery (PennCNP). Fluid intelligence was measured by a computerized version of the Raven's Progressive Matrices (SRAVENS). Analysis of variance indicated that gender, home language, quality of schooling, language of schooling and paternal education influenced performance on the SRAVEN. Stepwise multiple regression evidenced the importance of language, paternal education and high school language on SRAVENS responses. The assumption of non-verbal test scores as being independent of socio-demographic factors needs to be revisited as such independence cannot be maintained in light of such evidence.     

Brain damage,diagnosis, and substance abuse among violent offenders

Neuropsychological functioning, diagnoses, and substance abuse were compared among killers, nonhomicidal assaulters, and nonviolent offender controls. The Reitan and Luria-Nebraska Neuropsychological test batteries, the WAIS-R, CT scans, and EEGs were examined with a trend to more neuropathology found in killers and assaulters than in controls. There were no group differences in ICD-9 diagnosis nor on the MMPI, although considerable personality pathology was noted in all groups. Violent offenders scored higher on the Michigan Alcoholism Screening Test (MAST). The violent offenders were more likely to experience alcohol and drug-related mood dysphoria. The interaction of neuropsychological, personality, and substance abuse variables is discussed.     

A study of neuropsychological impairment among school-indentified learning-disabled students

This investigation examined the proportion of school-identified learning-disabled (LD) students who scored in the impaired range on the Halstead Reitan Neuropsychological Battery for Children (HNBC) over a 20-year period. A difference was noted in findings for periods before and after the passage of federal legislation (Public Law 94-142); specifically, the proportion of LD students who scored in the impaired range on neuropsychological tests was significantly higher prior to than after this law. A similar pattern of impaired performance across the different tests was noted before and after the legislation. The implications of these results for theorists and practitioners are discussed.     

Lack of awareness of neuropsychological deficit in cerebral small vessel disease: The relationship with executive and episodic memory functions

A common cause of neuropsychological impairment in older adults is cerebral small vessel disease (SVD), but little is known as to whether lack of awareness of neuropsychological impairment is a feature of this clinical condition. In this study, we investigated awareness deficits in a well‐phenotyped population of patients with SVD (n= 45; 21 with defined concomitant neuropsychological impairment) and made comparisons with 24 Alzheimer's disease (AD) patients and a further 80 control participants. Awareness of performance on a range of neuropsychological measures was examined based on the Brief Memory and Executive Test Battery (BMET) (Brookes, Hannesdottir, Lawrence, Morris, & Markus, 2012 ), exploring the relationship between awareness and memory and executive function. The results revealed significant awareness deficits in both the SVD and AD groups. When splitting the SVD group into those with or without concomitant neuropsychological impairment, only those with neuropsychological impairment showed reduced awareness. For the SVD group, executive function was significantly correlated with awareness but memory was not. By comparison, memory was significantly correlated with awareness in the AD group, with executive function showing a trend but remaining non‐significant. The results show that lack of awareness of deficit is a clinical feature of SVD and indicate that there are distinct neuropsychological associations with awareness deficit for SVD and AD.     

Luria-nebraska neuropsychological battery: High rates of false positives for geriatirc subjects

This study examined false positive rates obtained for two normal adult age groups, using three different methods for interpreting performances on the Luria-Nebraska Neuropsychological Battery (LNNB). Among normal subjects ages 18 to 30 and ages 65 to 85, false positive rates were found to range from 3.9% to 7.7% for younger subjects and 13.5% to 32.7% for older subjects. Significant differences were found between the proportion of false positives in each age group on each method of interpretation. A lack of agreement was found between the three different methods of interpretation concerningwhich subjects should be classified as impaired. Further analysis was performed by dividing older subjects into two groups, ages 65 to 70 and over 70. False positive rates for subjects over age 70 were found to range from 20.7% to 41.4%. Significant differences were also found between the proportion of false positives in each of these two groups.     

Neuropsychological assessment of learning disabilities: a discriminant analysis

The neuropsychological test scores of 23 learning disabled children were compared with those of a matched population of normal children in the 9-1 to 13-1 age range. All children were administered the Wechsler Intelligence Scale for Children-Revised (WISC-R), a dichotic listening task involving both free and directed recall conditions, a handedness inventory, the Tactile Performance Test and the Category Test from the Halstead-Reitan Neuropsychological Test Battery. A multivariate analysis of variance resulted in a significant separation between groups (p less than .001) using these procedures. A stepwise discriminant function analysis revealed that both of the directed dichotic tasks contributed the most of all 13 measures to the significant group separation. In addition, other cognitive tasks found to discriminate normal from learning disabled children include general verbal processes, concept formation, and tactile memory. These findings suggest that the directed dichotic listening procedure and the WISC-R Verbal IQ measure are reasonably valuable clinical tools in the classification of learning disabilities.     

Interpretation and use of the Luria-Nebraska battery

In a recent article, T. V. Akhutina and L. S. Tsvetkova (1983, Brain and Cognition 2, 129-134) presented an analysis of the Luria-Nebraska Neuropsychological Battery. Along with their generally positive review, they raised questions regarding the importance of the qualitative aspects of patients' performance in the interpretation of the battery. We agree with the authors that any interpretation of the battery which does not consider qualitative performance can limit the power and applicability of the battery. The procedures of item analysis and qualitative analysis are discussed as essential to a comprehensive interpretation of the battery. Also discussed are comments on additional scaling for the battery and the development of a standardized qualitative scoring system.     

Luria-nebraska neuropsychological battery: High rates of false positives for geriatirc subjects

This study examined false positive rates obtained for two normal adult age groups, using three different methods for interpreting performances on the Luria-Nebraska Neuropsychological Battery (LNNB). Among normal subjects ages 18 to 30 and ages 65 to 85, false positive rates were found to range from 3.9% to 7.7% for younger subjects and 13.5% to 32.7% for older subjects. Significant differences were found between the proportion of false positives in each age group on each method of interpretation. A lack of agreement was found between the three different methods of interpretation concerningwhich subjects should be classified as impaired. Further analysis was performed by dividing older subjects into two groups, ages 65 to 70 and over 70. False positive rates for subjects over age 70 were found to range from 20.7% to 41.4%. Significant differences were also found between the proportion of false positives in each of these two groups.     

Poly‐victimization and executive functions in junior college students

This study sought to characterize executive dysfunctions in poly‐victimized students without posttraumatic stress disorder (PTSD) symptoms and the relationship between neuropsychological and behavioral rating measures of executive functions (EFs). Based on self‐report data of exposure to victimization and PTSD symptoms, 259 junior college students aged 18–21 years were classified into four groups: poly‐victimization with PTSD symptoms (PVP), poly‐victimization without PTSD symptoms (PVnP), non‐poly‐victimization (nPV), and non‐victimization (nV). Respondents also completed the Behavior Rating Inventory of Executive Function‐Adult Version (BRIEF‐A). Of the 259 participants, 131 were administered a battery of neuropsychological tests from the Cambridge Neuropsychological Testing Automated Battery (CANTAB). The PVP group and the PVnP group performed worse than the nV group on most BRIEF‐A scales. When compared with the nPV group, the PVP group demonstrated poorer performance on the scales of Inhibit, Shift, Emotional Control, Initiate, and Working Memory, while the PVnP group performed more poorly on the Working Memory scale and the Task Monitor scale. For all BRIEF‐A scales, no significant differences were detected between the PVP group and the PVnP group. This study showed no between‐group differences for most of the neuropsychological tests except for the Stop Signal Task (SST), and no correlations between these two measures of EFs. Overall, we found evidence of an association between deficits in EFs and poly‐victimization. Although our study raises questions about the relationship between these two measures of EFs, it suggests that the use of the BRIEF‐A in conjunction with the CANTAB provides a more complete assessment of the executive dysfunctions.     

Relation of the Repeatable Battery for Assessment of Neuropsychological Status to measures of daily functioning in dementia

In the present study were examined relations of scores on the Repeatable Battery for the Assessment of Neuropsychological Status (Randolph, 1998) with measures of daily functioning in a sample with dementia. Participants (N=66) with various forms of dementia were seen at a dementia diagnostic clinic. All participants were administered the battery as part of a larger battery of neuropsychological measures. The participants' functional status was assessed by their primary caregivers, who completed the Physical Self-maintenance Scale and the Instrumental Activities of Daily Living scale (Lawton & Brody, 1969) as part of a social work interview. Analysis indicated that the Repeatable Battery for Assessment of Neuropsychological Status, particularly the Attention, Visuospatial/Constructional, and Immediate Memory indices, strongly correlated with measures of daily functioning. These results were supported by multiple regression analyses showing the RBANS Attention and Immediate Memory indices as significant predictors of functional abilities. One may conclude the RBANS should be favorably considered in understanding the functional problems of probable dementing patients.     

Reported prevalence of attentional difficulties in a general sample of college students

The present study investigated the self-reported prevalence of attention-deficit hyperactivity disorder (ADHD)symptoms in 770 college students using the Adult Rating Scale and the Wender Utah Rating Scale. Psychometric properties of these scales were explored. The study also investigated the performance of students with ADHD symptoms, relative to students without ADHD symptoms, on a battery of neuropsychological tasks. Results revealed that 7 and 8% of the students reported significant symptoms (i.e., 1.5 SD above the mean) on the Adult Rating Scale and the Wender Utah Rating scale, respectively, and 2.5% reported significant symptoms on both the Adult Rating Scale and the Wender Utah Rating Scale. Using more stringent criteria (two standard deviations), fewer (i.e, 4, 3.8%, and 0.5%) subjects reported significant symptoms associated with ADHD. Between-group differences were found on one of the neuropsychological tasks. The construct validity of the rating scales was supported. Limitations and implications for future research are advanced.Presented at the International Neuropsychological Society's Sixteenth European Conference, Angers, France, June 1994, and the Annual Convention of the American Psychological Association, Los Angeles, CA, August 1994.     

Obsessive compulsive disorder,checking, and non-verbal memory: a neuropsychological investigation

There is considerable evidence in the literature for the presence of non-verbal and praxic memory deficits in OCD. Such deficits may represent the cognitive substrate of doubt-related phenomenon such as checking. Neuropsychological tests of non-verbal memory functioning and memory for actions were administered to patients with OCD (whose predominant symptom was checking) and a group of matched healthy controls. Significant differences were found between the experimental and control groups, suggesting some memory impairment in the OCD group; however, no significant relationship was found linking neuropsychological test indices with checking. Significant relationships were found linking recognition memory problems and immediate memory for actions with general symptom severity.     

Comparison of the Luria-Nebraska Neuropsychological Battery-Children's Revision and the WISC-R with learning disabled children

This investigation concerned the relationship between the Luria-Nebraska Neuropsychological Battery--Children's Revision and the WISC--R for a sample of 32 children identified as learning disabled. The children's mean age was 9 yr., 11 mo.; they were identified as learning disabled on the basis of ability (WISC--R)/achievement discrepancy test scores. The sample was of low average intellectual ability according to the WISC--R and the Luria-Nebraska T-scores. Intercorrelations between scores on the WISC--R and Luria-Nebraska lists were generally nonsignificant, with the exception of language and arithmetic measures on each test. Also, 84% or 27 of the present sample of 32 were correctly identified as learning disabled using a criterion of three or more Luria-Nebraska subscale scores greater than one SD above the mean.     

Differential effects of cognitive behavior modification on seriously emotionally disturbed adolescents exhibiting internalizing or externalizing problems

This study examined the differential effects of a school-based cognitive behavior modification intervention on (a) the interpersonal/social skills and (b) the social competence and school adjustment of two groups of middle school students identified as seriously emotionally disturbed. One groups of students exhibited internalizing emotional problems and the other group exhibited externalizing emotional problems. The objective of the study was to investigate whether the effectiveness of a school-based cognitive behavior modification intervention was significantly related to the type of emotional disturbance a student exhibits (i.e. internalizing or externalizing emotional disturbance). The sample consisted of an experimental and a control group of middle school students identified as seriously emotionally disturbed. The intervention was implemented in 23 biweekly 42-minute sessions. The results indicated that teacher ratings of student social competence and school adjustment were sensitive to treatment effects, although students' social skills self-ratings were not significantly affected by the treatment. A differential treatment effect was established in that externalizing students were significantly more responsive than internalizing students.     

Sex differences in strategy and performance on computerized neuropsychological tests as related to gender identity and age at puberty

Neuropsychological sex differences have since long been under debate. Support for the relation between behavioral differences and biological variables like hormone influence is, however, emerging. Sixteen men and sixteen women, all university students, were tested with computerized neuropsychological tests (APT), the Bem Sexual Role Inventory, and asked about pubertal age. The results were in line with earlier findings of sex differences in neuropsychological tests, men being faster and women more cautious. The assumption that women tend to use left-hemispheric, verbal/serial strategies also in spatial tasks was also partly supported. In women, late onset of puberty was related to better spatial performance, and there were also more intercorrelations between verbal and spatial tests in the female than in the male group, indicating that women use less specific strategies (more g-factor intelligence) in problem solving, or that aptitudes are less compartmentalized in women than in men.     

学习困难儿童的神经心理研究

本研究用中国修订的HR成套神经心理测验(HRB(m)-RC)、韦氏儿童智力量表(WISC-CR)、韦氏记忆量表(WMS-RC)和分类测验测查9—14岁学习困难儿童和正常儿童各50名。研究了学习困难儿童的神经心理特点和神经心理功能与学习成绩的关系,从神经心理学角度来讨论学习困难的教育干预。