Treatment of nocturnal enuresis by conditioning techniques

One hundred and fifteen enuretic children were assigned to five treatment groups. Three groups received Mowrer-type continuous signal (C.S.), Twin-Signal (T.S.) or intermittent Twin Signal (T.S.-I.R.) conditioning treatment, and two groups were given “placebo” or “arousal” control treatments. Over a one-month period, there was no difference between conditioning and control procedures, and it was concluded that further research is needed to determine the basis of treatment response. There was no evidence in support of the escape training hypothesis, and the twin-signal modification to standard bell-and-pad treatment is not recommended. The investigation confirmed the success of conditioning treatment in bringing about the initial arrest of enuresis (i.e. in 81.4 per cent of the cases) but the relapse rate was high. The investigation provided tentative evidence that intermittent conditioning treatment offers one way of reducing the frequency of relapse. The problem of obtaining satisfactory parental co-operation in a badly housed working-class population was apparent, and ways of reducing the demands that treatment imposes on parents are indicated. The results are discussed with regard to theories of conditioning treatment of nocturnal enuresis, and possible improvements in this technique of treatment.     

Behavior modification of aggressive behavior on a nursery school bus: A case study

A case study is presented in which aggressive behavior of two preschool boys on a nursery school bus was modified by the introduction of a negative punishment contingency in which the Ss were told they would be detained on the bus until the second time the bus passed their house (delay of reinforcement) if abusive behavior occurred. The practical implications of the study and the relative merits of choosing negative punishment over positive punishment as therapy with children are discussed.     

Treatment effects of a total behavior modification program with five autistic children

Five autistic children were studied intensively to devise effective treatment procedures with the goal of eventual return to their homes. An experimental-clinical approach was used to design behavior modification programs specifically for each child. All children made varying degrees of progress, but thier learning deficits continued to interfere with learning all new responses, necessitating continuation of a structured home or institutional existence to maintain the treatment gains. Retardation remained a characteristic of all children, retrieval of previously decelerated referral behaviors was problematic at date of discharge, and response acquisition did not appreciably facilitate learning of more complex behavior on the same response hierarchy.     

Relative efficacy of methylphenidate and behavior modification in hyperkinetic children: An interim report

Children reported to be hyperactive in school and with behavior difficulties at home were randomly assigned to methylphenidate, behavior therapy and placebo, or behavior therapy with methylphenidate for an 8-week period. Rating scales were obtained from teachers and parents. Independent blind observers rated childrens' classroom behavior on a weekly basis. A behavior therapy program was implemented in the home and at school. Methylphenidate dosage was individualized. Ratings of behavior deviance were significantly reduced by all treatments. However, a significant advantage for the groups receiving methylphenidate was found over the group receiving behavior therapy and placebo. No significant differences between methylphenidate alone and methylphenidate combined with behavior therapy were obtained. Global ratings of improvement done by teachers favored the combined treatment of behavior therapy and methylphenidate over behavior therapy and placebo. No differences among treatments were found in the mothers' global ratings of improvement. The results indicate that though all three treatments were effective, methylphenidate was significantly superior to behavior therapy alone.This study was supported in part by grant MH 18579, and by grant No. 3-621 from the Long Island Jewish-Hillside Medical Center. The authors wish to thank the behavior therapists, Drs. Jeffrey Felixbrod and Marion Pheterson, as well as Ms. Patricia Ramsey, who was responsible for data analysis.     

红斑性肢痛症合并周围神经损害1例诊治分析

红斑性肢痛症是一种罕见的临床综合征,以肢端皮肤间歇性皮温升高、发红、肿胀及烧灼样痛为特点,病变主要累及四肢末端,尤以下肢多见,多呈对称分布,较少见于面部和耳部.其症状常因运动和遇热而加重,休息和遇冷而减轻.临床上常分为原发性和继发性两大类,其中原发性红斑性肢痛症,多认为与编码Nav1.7亚单位的SCN9A基因突变有关.目前该病发病机制尚不明确,治疗上缺乏确切有效的治疗方案,临床易误诊误治.本文报道了红斑性肢痛症合并周围神经损害1例,以期提高对该病的认识.