Enhanced feminine sexual behavior and infertility in female rats prenatally treated with an antiestrogen

An attempt to elucidate the possible role of prenatal estrogen on the development of feminine sexual behavior and reproductive function was made by treating females with the antiestrogen CI628 prenatally on days 13-19. Control females were prenatally treated with saline or remained untreated. The animals were delivered by caesarian section on day 22 of pregnancy and placed with foster mothers whose newborn pups had been previously removed. Intact peripubertal females in each treatment group were observed for several reproductive measures, including the capacity to become pregnant. Other females were ovariectomized in adulthood and treated with estradiol benzoate (EB) (1, 1.5, 2 or 4 micro g/rat) and 0.5 mg progesterone and tested for receptivity, proceptivity and sexual partner preference. Two weeks after the completion of these tests, the females were injected daily for 7 days with 0.25 mg testosterone and tested for sexual partner preference and mounting behavior. The results obtained showed accelerated vaginal opening, and infertility in the antiestrogen-treated intact females and enhanced receptivity and proceptivity in response to 1 micro g EB in the antiestrogen ovariectomized females. Sexual partner preference and mounting behavior did not differ between groups. These results suggest an involvement of prenatal estrogen on the development of female reproductive function, but not on behavioral differentiation.     

Habenular lesions and feminine sexual behavior of ovariectomized rats: diminished responsiveness to the synergistic effects of estrogen and progesterone.

Bilateral electrolytic lesions in the habenula resulted in disruption of estrogen-progesterone-evoked feminine sexual behaviors of ovariectomized female rats. There were no difference between lesioned and sham-operated animals in tests conducted after the administration of estrogen alone. Animals with lesions were characterized by an increased proportion of mounts not followed by lordosis, a decreased proportion of mounts followed by pronounced lordosis, and a decreased proportion of mounts preceded by soliciting behaviors. Lesions had a negligible effect upon the tendency to hold lordotic postures after the male dismounted. The results suggested that the habenula is involved in modulating responsiveness to the synergistic effects of estrogen and progesterone.     

The influence of male and female best friends on adolescent sexual behavior

Using panel data from a junior high school system in an urban area of Florida, we examine whether adolescents' best same-sex and best opposite-sex friends' sexual intercourse behavior increases the likelihood that respondents who are virgins at round 1 will make the transition to intercourse between rounds of our study. We find no significant influence effects of friends of either sex for black males or females, or white males. In contrast, white females are influenced by the sexual behavior of both their best female friend and best male friend. A virgin white female whose best friends of both sexes were sexually experience at round 1 was almost certain to have sexual intercourse within the two years of our study.     

The effects of family structure on the sexual behavior of adolescents.

The effects of two family structures, single- and two-parent homes, on adolescent sexual behavior were studied. The variables of race, age, and gender were controlled. The analysis compared the age at first intercourse, frequency of intercourse in the last four weeks, and virgin/nonvirgin status of adolescents from black single-parent families, white single-parent families, black two-parent families, and white two-parent families. For males, the two-parent family was related to less sexual activity and older age at first intercourse. For females, the two-parent family was not as important as race in influencing sexual behavior. The white females from two-parent families were more likely to be virgins, but once having had sexual intercourse, tended to have a higher level of sexual activity than did black females from two-parent homes.     

Adolescent sexual behavior.

Pregnancy and sexually transmitted diseases among adolescents is considered a major problem in our society. The purpose of this study is to review the past five years of professional literature on adolescent sexuality to determine the factors which influence this social phenomenon as well as effective interventions. The importance of the family and religion on sexual attitudes and behaviors, how sexual activity is related to other age-related behaviors and delinquency, the relationship between early coital behaviors and the risk of pregnancy and sexually transmitted diseases, and attitudes toward contraception and abstinence are discussed. Also addressed are the possible psychological effects of sexual activity on the development of the adolescent.     

The influence of individual characteristics and severity of harassing behavior on reactions to sexual harassment

Differences in reactions to 18 scenarios depicting potentially sexually harassing situations were studied as a function of harassment severity and individual level factors. The scenarios illustrate a continuum of behavior, with some situations depicting overt sexual harassment and others portraying more innocuous behaviors. The individuals' reactions were strongly influenced by the perceived severity of the incidents. Reactions were influenced to a lesser extent by the individual level factors of gender, attitudes toward women, religiosity, and locus of control. Among these factors, gender had the strongest effect on reaction types. Findings indicate that harassment severity and individual level factors may combine to influence reactions to sexual harassment.The authors would like to thank Barbara Gutek and Gary Powell for their comments on an early draft of this paper.     

Differential influence of stereoisomers of estradiol on sexual behavior of female hamsters

Morphological and behavioral responses to estradiol-17 beta (E2-17 beta) and estradiol-17 alpha (E2-17 alpha) were examined in a series of three experiments. The E2-17 beta augmented uterine growth in hamsters to a greater extent than did E2-17 alpha. Lordosis in ovariectomized adults was elicited by treatment with E2-17 beta but not with E2-17 alpha (each tested in combination with progesterone). When administered neonatally only E2-17 beta disrupted estrous cyclicity in the intact female and induced the ability to mount in ovariectomized, androgen-treated adults. These results suggest the existence of a stereospecific response to estrogenic stimulation in neural tissue comparable with that occurring in the uterus.     

AIDS: late adolescents' knowledge and its influence on sexual behavior

Approximately 300 late adolescents were surveyed to assess their knowledge of AIDS, and to determine if and how their sexual behavior had changed as a result. Findings suggested that late adolescents were quite knowledgeable regarding AIDS and its transmission; however, only about one-third had altered their sexual behavior as a result of fear of the disease. Findings are discussed in terms of the need for AIDS education, and recommendations are presented.